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Research Article

JC virus T' proteins encoded by alternatively spliced early mRNAs enhance T antigen-mediated viral DNA replication in human cells

Pages 250-264 | Published online: 10 Jul 2009

References

  • Aebi M, Hornig H, Padgett RA, Reiser J, Weissmann C (1986). Sequence requirements for splicing of higher eu-karyotic nuclear pre-mRNA. Cell 47: 555–565.
  • Bikel I, Mamon H, Brown EL, Boltax J, Agha M, Livingston DM (1986). The t-unique coding domain is important to the transformation maintenance function of the simian virus 40 small t antigen. Mol Cell Biol 6: 1172–1178.
  • Bollag B, Chuke W-F, Frisque RJ (1989). Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: identification of sequences important for efficient transformation. I Virol 63: 863–872.
  • Bollag B, Prins C, Snyder EL, Frisque RJ (2000). Purified JC virus T and T' proteins differentially interact with the retinoblastoma family of tumor suppressor proteins. Virology 274: 165–178.
  • Brodsky JL, Pipas JM (1998). Polyomavirus T anti-gens: molecular chaperones for multiprotein complexes. I Virol 72: 5329–5334.
  • Campbell KS, Mullane KP, Aksoy IA, Stubdal H, Zalvide J, Pipas JM, Silver PA, Roberts TM, Schafthausen BS, DeCaprio JA (1997). DnaJ/hsp40 chaperone domain of 5V40 large T antigen promotes effi-cient viral DNA replication. Gene Dev 11: 1098–1110.
  • Cegielska A, Moarefi I, Fanning E, Virshup DM (1994a). T-antigen kinase inhibits simian virus 40 DNA replication by phosphorylation of intact T antigen on serines 120 and 123. J. Virol 68: 269–275.
  • Cegielska A, Shaffer S, Derua R, Goris J, Virshup DM (1994b). Different oligomeric forms of protein phos-phatase 2A activate and inhibit simian virus 40 DNA replication. Mol Cell Biol 4: 4616–4623.
  • Chuke W-F, Walker DL, Peitzman LB, Frisque RJ (1986). Construction and characterization of hybrid poly-omavirus genomes. I Virol 60: 960–971.
  • Dornreiter I, Höss A, Arthur AK, Fanning E (1990). SV40 T antigen binds directly to the large subunit of purified DNA polymer ase alpha. EMBO J9: 3329–3336.
  • Elliot DJ (2000). Splicing and the single cell. Histol Histopathol 15: 239–249.
  • Fanning E (1992). Simian virus-40 large T-antigen-the puzzle, the pieces, and the emerging picture. I Virol 66: 1289–1293.
  • Frisque RJ (1983). Regulatory sequences and virus-cell interactions of JC virus. In: Polyomaviruses and hu-man neurological disease. Sever JL, Madden DL (ed). New York: Alan R. Liss, Inc, pp 41–59.
  • Frisque RJ (1999). JC and BK viruses (Papovaviridae). In: Encyclopedia of Virology. Granoff A, Webster RG, (eds). Academic Press: London, pp 876–883.
  • Frisque RJ, Bream GL, Cannella MT (1984). Human poly-omavirus JC virus genome. I Virol 51: 458–469.
  • Frisque RJ, White FA III (1992). The molecular biology of JC virus, causative agent of progressive multifocal leukoen-cephalopathy. In: Molecular neurovirology. Roos RP (ed). Totowa, NJ: Humana Press, pp 25–158.
  • Haggerty S, Walker DL, Frisque RJ (1989). JC virus-simian virus 40 genomes containing heterologous regulatory signals and chimeric early regions: identification of re-gions restricting transformation by JC virus. I Virol 63: 2180–2190.
  • Hirt B (1967). Selective extraction of polyoma DNA from infected mouse cell cultures. I Mol Biol 26: 365–369.
  • Krawczak M, Reiss J, Cooper DN (1992). The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: causes and conse-quences. Hum Genet 90: 41–54.
  • Lopez AJ (1998). Alternative splicing of pre-mRNA: devel-opmental consequences and mechanisms of regulation. Annu Rev Genet 32: 279–305.
  • Lynch KJ, Frisque RJ (1990). Identification of critical ele-ments within the JC virus DNA replication origin. I Virol 64: 5812–5822.
  • Lynch KJ, Haggerty S, Frisque RJ (1994). DNA replication of chimeric JC virus-simian virus 40 genomes. Virology 204: 819–822.
  • Molin M, Akusjärvi G (2000). Overexpression of essential splicing factor ASF/5F2 blocks the temporal shift in ade-novirus pre-mRNA splicing and reduces virus progeny formation. I Virol 74: 9002–9009.
  • Mount SM (1982). A catalogue of splice junction sequences. Nucleic Acids Res 10: 459–472.
  • Noble JCS, Pan ZQ, Prives C, Manley JL (1987). Splicing of 5V40 early pre-mRNA to large T and small t mRNAs utilizes different patterns of lariat branch sites. Cell 50: 227–236.
  • Padgett RA, Konarska MM, Aebi M, Hornig H, Weissman C, Sharp PA (1985). Nonconsensus branch-site sequences in the in vitro splicing of transcripts of mutant rabbit beta-globin genes. Proc Nail Acad Sci USA 82: 8349–8353.
  • Pipas JM (1992). Common and unique features of T-antigens encoded by the polyomavirus group. I Virol 66: 3979–3985.
  • Prives C (1990). The replication functions of 5V40 T anti-gen are regulated by phosphorylation. Cell 61: 735–738.
  • Reed R, Maniatis T (1985). Intron sequences involved in lariat formation during pre-mRNA splicing. Cell 41: 95–105.
  • Ruskin B, Greene JM, Green MR (1985). Cryptic branch point activation allows accurate in vitro splicing of hu-man beta-globin intron. Cell 41: 833–844.
  • Scheidtmann KH, Mumby MC, Rundell K, Walter G (1991a). Dephosphorylation of simian virus-40 large-T antigen and p53 protein by protein phosphatase-2A-inhibition by small-T antigen. Mol Cell Biol 11: 1996–2003.
  • Scheidtmann KH, Virshup DM, Kelly TJ (1991b). Pro-tein phosphatase-2A dephosphorylates simian virus-40 large T-antigen specifically at residues involved in regulation of DNA-binding activity. I Virol 65: 2098–2101.
  • Sheng Q, Denis D, Ratriofsky M, Roberts TM, DeCaprio JA, Schaffhausen B (1997). The DnaJ domain of poly-omavirus large T is required to regulate RB family tumor suppressor function. I Virol 71: 9410–9416.
  • Smale ST, Tjian R (1986). T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication. Mol Cell Biol 6: 4077–4087.
  • Sock E, Enderich J, Wegner M (1999). The J domain of papovaviral large tumor antigen is required for syn-ergistic interaction with the POU-domain protein Tst-1/Oct6/SCIP. Mol Cell Biol 19: 2455–2464.
  • Sock E, Wegner M, Fortunato EA, Grummt F (1993). Large T-antigen and sequences within the regulatory region of JC virus both contribute to the features of JC virus DNA replication. Virology 197: 537–548.
  • Sompayrac LM, Danna KJ (1981). Efficient infection of monkey cells with DNA of simian virus 40. Proc Nat] Acad Sci USA 78: 7575–7578.
  • Stillman B (1994). Smart machines at the replication fork. Cell 78: 725–728.
  • Stoj dl DF, Bell JC (1999). SR protein kinases: the splice of life. Biochem Cell Biol 77: 293–298.
  • Sullivan CS, Cantalupo P, Pipas JM (2000a). The molecu-lar chaperone activity of simian virus 40 large T anti-gen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism. Mol Cell Biol 20: 6233–6243.
  • Sullivan CS, Tremblay JD, Fewell SW, Lewis JA, Brodsky JL, Pipas JM (2000b). Species-specific elements in the large T-antigen J domain are required for cellular trans-formation and DNA replication by simian virus 40. Mol Cell Biol 20: 5749–5757.
  • Swenson JJ, Frisque RJ (1995). Biochemical characteriza-tion and localization of JC virus large T antigen phos-phorylation domains. Virology 212: 295–308.
  • Swenson JJ, Trowbridge PW, Frisque RJ (1996). Replica-tion activity of JC virus large T antigen phosphoryla-tion and zinc finger domain mutants. I Neurovirol 2: 78–86.
  • Tevethia SS, Epler M, Georgoff I, Teresky A, Marlow M, Levine AJ (1992). Antibody response to human papo-vavirus JC (JCV) and simian virus-40 (5V40) T-antigens in 5V40 T antigen-transgenic mice. Virology 190: 459–464.
  • Trowbridge PW, Frisque RJ (1993). Analysis of G418-selected Rat2 cells containing prototype, variant, mu-tant, and chimeric JC-virus and SV40 genomes. Virology 196: 458–474.
  • Trowbridge PW, Frisque RJ (1995). Identification of three new JC virus proteins generated by alternative splicing of the early viral mRNA. J NeuroVirol 1: 195–206.
  • Wegner M, Drolet DW, Rosenfeld MG (1993). Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoen-cephalopathy. Proc Nat] Acad Sci USA 90: 4743–4747.
  • Weisshart K, Taneja P, Jenne A, Herbig U, Simmons DT, Fanning E (1999). Two regions of simian virus 40 T anti-gen determine cooperativity of double-hexamer assem-bly on the viral origin of DNA replication and promote hexamer interactions during bidirectional origin DNA unwinding. I Virol 73: 2201–2211.

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