2
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Diazepam inhibits HIV-1 Tat-induced migration of human microglia

Pages 481-486 | Published online: 10 Jul 2009

References

  • Albini A, Benelli R, Giunciuglio D, Cal T, Mariani G, Ferrini S, Noonan DM (1998a). Identification of a novel domain of HIV Tat involved in monocyte chemotaxis. I Biol Chem 273: 15895–15900.
  • Albini A, Ferrini S, Benelli R, Sforzini S, Giunciuglio D, Aluigi MG, Proudfoot AE, Alouani S, Wells TN, Mariani G, Rabin RL, Farber JM, Noonan DM (1998b). HIV-1 Tat protein mimicry of chemokines. Proc Nat] Acad Sci USA 95: 13153–13158.
  • Bessler H, Weizman R, Gavish M, Notti I, DjaldettiM (1992). Immunomodulatory effect of peripheralbenzodiazepine receptor ligands on human mononuclear cells. I Neu-roimmunol 38: 19–25.
  • Bonwetsch R, Croul S, Richardson MW, Lorenzana C, Valle LD, Sverstiuk AE, Amini S, Morgello S, Khalili K, Rappaport J (1999). Role of HIV-1 Tat and CC chemokine MIP-1alpha in the pathogenesis of HIV associated cen-tral nervous system disorders. J NeuroVirol 5: 685–694.
  • Braestrup C, Squires RF (1977). Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding. Proc Nat] Acad Sci USA 74: 3805–3809.
  • Canat X, Carayon P, Bouaboula M, CahardD, Shire D, Roque C, Le Fur G, Casellas P (1993). Distribution profile and properties of peripheral-type benzodiazepine receptors on human hemopoietic cells. Life Sci 52: 107–118.
  • Chao CC, Gekker G, Hu S, Peterson PK (1994). Human mi-croglial cell defense against toxoplasma gondii. The role of cytokines. Jimmunol 152: 1246–1252.
  • Chao CC, Hu S, Shark KB, Sheng WS, Gekker G, Peterson PK (1997). Activation of mu opioid receptors inhibits microglial cell chemotaxis. J Pharmacol Exp Ther 281: 998–1004.
  • Drugan RC (1994). Are the nonmitochondrial peripheral benzodiazepine receptors on leukocytes a novel inter-mediary of brain, behavior, and immunity? Lab Invest 70: 1–5.
  • Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, Morgan RA, Wingfield P, Gallo RC (1993). Release, uptake, and effects of extracellular human immunodefi-ciency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 67: 277–287.
  • Grynkiewicz G, Poenie M, Tsien RY (1985). A new gener-ation of Ca2+ indicators with greatly improved fluores-cence properties. J Biol Chem 260: 3440–3450.
  • Hegg CC, Hu S, Peterson PK, Thayer SA (2000). Beta-chemokines and human immunodeficiency virus type-1 proteins evoke intracellular calcium increases in human microglia. Neuroscience 98: 191–199.
  • Jones M, Olafson K, Del Bigio MR, Peeling J, Nath A (1998). Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement. I Neu-ropathol Exp Neurol 57: 563–570.
  • Lafrenie RM, Wahl LM, Epstein JS, Hewlett IK, Yamada KM, Dhawan S (1996). HIV-1-tat protein promotes chemo-taxis and invasive behavior by monocytes. I Immunol 157: 974–977.
  • Le Fur G, Perrier ML, Vaucher N, Imbault F, Flamier A, Be-navides J, Uz an A, Renault C, Dubroeucq MC, Gueremy C (1983). Peripheral benzodiazepine binding sites: Ef-fect of PK 11195, 1-(2-chloropheny1)-n-methyl-n-(1-methylpropy1)-3-isoquinolinecarboxamide. I. In vitro studies. Life Sci 32: 1839–1847.
  • Lokensgard JR, Gekker G, Hu S, Arthur AF, Chao CC, Peterson PK (1997). Diazepam-mediated inhibition of human immunodeficiency virus type 1 expression in human brain cells. Antimicrob Agents Chem other 41: 2566–2569.
  • Matsumoto T, Ogata M, Koga K, Shigematsu A (1994). Ef-fect of peripheral benzodiazepine receptor ligands on lipopolysaccharide-induced tumor necrosis factor ac-tivity in thioglycolate-treated mice. Antimicrob Agents Chemother 38: 812–816.
  • Mohler H, Okada T (1977). Benzodiazepine receptor: Demonstration in the central nervous system. Science 198: 849–851.
  • Squires RF, Braestrup C (1977). Benzodiazepine receptors in rat brain. Nature 266: 732–734.
  • Thayer SA, Sturek M, Miller RJ (1988). Measurement of neuronal Ca2+ transients using simultaneous microflu-orimetry and electrophysiology. Pflugers Arch—Eur I Phys 412: 216–223.
  • Weiss JM, Nath A, Major EO, Berman JW (1999). HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the hu-man blood-brain barrier and up-regulates CCR5 ex-pression on human monocytes. I Immunol 163: 2953–2959.
  • Werth JL, Thayer SA (1994). Mitochondria buffer physio-logical calcium loads in culture drat dorsal root ganglion neurons. J Neurosci 14: 348–356.
  • Westendorp MO, Frank R, Ochsenbauer C, Sticker K, Dhein J, Walczak H, Debatin KM, Krammer PH (1995). Sensitization of T cells to CD95-mediated apop-tosis by HIV-1 Tat and gp120. Nature 375: 497–500.
  • Yao J, Harvath L, Gilbert DL, Colton CA (1990). Chemotaxis by a CNS macrophage, the microglia. J Neurosci Res 27: 36–42.
  • Zavala F, Haumont J, Lenfant M (1984). Interaction of ben-z o diazepines with mouse macrophages. EurJPharmacol 106: 561–566.
  • Zavala F, Taupin V, Descamps-Latscha B (1990). In vivo treatment with benzodiazepines inhibits murine phago-cyte oxidative metabolism and production of inter-leukin 1, tumor necrosis factor and interleukin-6. JPhar-macol Exp Ther 255: 442–450.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.