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Research Article

Human T-cell leukemia virus type I Tax induces the expression of dendritic cell markers associated with maturation and activation

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Pages 358-371 | Published online: 10 Jul 2009

References

  • Alefantis T, Barmak K, Harhaj E W, Grant C, Wigdahl B. 2003. Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax. J Biol Chem. 278: 21814–21822. [PUBMED], [INFOTRIEVE]
  • Ballard D W, Bohnlein E, Lowenthal J W, Wano Y, Franza B R, Greene W C. 1988. HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. Science. 241: 1652–1655. [PUBMED], [INFOTRIEVE]
  • Barmak K, Harhaj E, Grant C, Alefantis T, Wigdahl B. 2003a. Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegeneration. Virology. 308: 1–12. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Barmak K, Harhaj E W, Wigdahl B. 2003b. Mediators of central nervous system damage during the progression of human T-cell leukemia type I-associated myelopathy/tropical spastic paraparesis. J NeuroVirol. 9: 522–529. [PUBMED], [INFOTRIEVE]
  • Bennett S R, Carbone F R, Karamalis F, Miller J F, Heath W R. 1997. Induction of a CD8+ cytotoxic T lymphocyte response by cross-priming requires cognate CD4+ T cell help. J Exp Med. 186: 65–70. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Brady J N. 1992. Extracellular Tax1 protein stimulates NF-kB and expression of NF-kB-responsive Ig kappa and TNF beta genes in lymphoid cells. AIDS Res Hum Retroviruses. 8: 724–727. [PUBMED], [INFOTRIEVE]
  • Buelens C, Verhasselt V, De, Groote D, Thielemans K, Goldman M, Willems F. 1997. Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin-10. Eur J Immunol. 27: 1848–1852. [PUBMED], [INFOTRIEVE]
  • Canque B, Camus S, Yagello M, Gluckman J C. 1998. IL-4 and CD40 ligation affect differently the differentiation, maturation, and function of human CD34+ cell-derived CD1a+CD14− and CD1a−CD14+ dendritic cell precursors in vitro. J Leukoc Biol. 64: 235–244. [PUBMED], [INFOTRIEVE]
  • Cartier Rovirosa L, Ramirez E, Flores R. 2003. Chronic expression of Tax protein in cerebrospinal fluid cells and spinal fluid (CSF) would be a pathogenic condition of HAM/TSP. 11th International Conference on Human Retrovirology: HTLV and Related Viruses. San Francisco
  • Chefalo P J, Harding C V. 2001. Processing of exogenous antigens for presentation by class I MHC molecules involves post-Golgi peptide exchange influenced by peptide-MHC complex stability and acidic pH. J Immunol. 167: 1274–1282. [PUBMED], [INFOTRIEVE]
  • De, Smedt T, Van, Mechelen M, De, Becker G, Urbain J, Leo O, Moser M. 1997. Effect of interleukin-10 on dendritic cell maturation and function. Eur J Immunol. 27: 1229–1235. [PUBMED], [INFOTRIEVE]
  • Dhib-Jalbut S, Hoffman P M, Yamabe T, Sun D, Xia J, Eisenberg H, Bergey G, Ruscetti F W. 1994. Extracellular human T-cell lymphotropic virus type I Tax protein induces cytokine production in adult human microglial cells. Ann Neurol. 36: 787–790. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Dudziak D, Kieser A, Dirmeier U, Nimmerjahn F, Berchtold S, Steinkasserer A, Marschall G, Hammerschmidt W, Laux G, Bornkamm G W. 2003. Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway. J Virol. 77: 8290–8298. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Durand D B, Bush M R, Morgan J G, Weiss A, Crabtree G R. 1987. A 275 basepair fragment at the 5′ end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor. J Exp Med. 165: 395–407. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Elovaara I, Koenig S, Brewah A Y, Woods R M, Lehky T, Jacobson S. 1993. High human T cell lymphotropic virus type 1 (HTLV-1)-specific precursor cytotoxic T lymphocyte frequencies in patients with HTLV-1-associated neurological disease. J Exp Med. 177: 1567–1573. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Fanales-Belasio E, Moretti S, Nappi F, Barillari G, Micheletti F, Cafaro A, Ensoli B. 2002. Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses. J Immunol. 168: 197–206. [PUBMED], [INFOTRIEVE]
  • Franklin A A, Kubik M F, Uittenbogaard M N, Brauweiler A, Utaisincharoen P, Matthews M A, Dynan W S, Hoeffler J P, Nyborg J K. 1993. Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB). J Biol Chem. 268: 21225–21231. [PUBMED], [INFOTRIEVE]
  • Giovanna Quaranta M, Tritarelli E, Giordani L, Viora M. 2002. HIV-1 Nef induces dendritic cell differentiation: a possible mechanism of uninfected CD4(+) T cell activation. Exp Cell Res. 275: 243–254. [CROSSREF]
  • Grant C, Barmak K, Alefantis T, Yao J, Jacobson S, Wigdahl B. 2002. Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation. J Cell Physiol. 190: 133–159. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Gunzer M, Friedl P, Niggemann B, Brocker E B, Kampgen E, Zanker K S. 2000. Migration of dendritic cells within 3-D collagen lattices is dependent on tissue origin, state of maturation, and matrix structure and is maintained by proinflammatory cytokines. J Leukoc Biol. 67: 622–629. [PUBMED], [INFOTRIEVE]
  • Hinz M, Loser P, Mathas S, Krappmann D, Dorken B, Scheidereit C. 2001. Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells. Blood. 97: 2798–2807. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Hoffman P M, Dhib-Jalbut S, Mikovits J A, Robbins D S, Wolf A L, Bergey G K, Lohrey N C, Weislow O S, Ruscetti F W. 1992. Human T-cell leukemia virus type I infection of monocytes and microglial cells in primary human cultures. Proc Natl Acad Sci U S A. 89: 11784–11788. [PUBMED], [INFOTRIEVE]
  • Husmann L A, Bevan M J. 1988. Cooperation between helper T cells and cytotoxic T lymphocyte precursors. Ann N Y Acad Sci. 532: 158–169. [PUBMED], [INFOTRIEVE]
  • Jacobson S, McFarlin D E, Robinson S, Voskuhl R, Martin R, Brewah A, Newell A J, Koenig S. 1992. HTLV-I-specific cytotoxic T lymphocytes in the cerebrospinal fluid of patients with HTLV-I-associated neurological disease. Ann Neurol. 32: 651–657. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Jacobson S, Shida H, McFarlin D E, Fauci A S, Koenig S. 1990. Circulating CD8+ cytotoxic T lymphocytes specific for HTLV-I pX in patients with HTLV-I associated neurological disease. Nature. 348: 245–258. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Jacobson S, Zaninovic V, Mora C, Rodgers-Johnson P, Sheremata W A, Gibbs C J, Jr, Gajdusek C, McFarlin D E. 1988. Immunological findings in neurological diseases associated with antibodies to HTLV-I: activated lymphocytes in tropical spastic paraparesis. Ann Neurol. 23(Suppl)S196–S200. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Jonuleit H, Knop J, Enk A H. 1996. Cytokines and their effects on maturation, differentiation and migration of dendritic cells. Arch Dermatol Res. 289: 1–8. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Jorgensen T N, Haase C, Michelsen B K. 2002. Treatment of an immortalized APC cell line with both cytokines and LPS ensures effective T-cell activation in vitro. Scand J Immunol. 56: 492–503. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Karttunen J, Sanderson S, Shastri N. 1992. Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens. Proc Natl Acad Sci U S A. 89: 6020–6024. [PUBMED], [INFOTRIEVE]
  • Knight S C, Macatonia S E, Cruickshank K, Rudge P, Patterson S. 1993. Dendritic cells in HIV-1 and HTLV-1 infection. Adv Exp Med Biol. 329: 545–549. [PUBMED], [INFOTRIEVE]
  • Kohrgruber N, Halanek N, Groger M, Winter D, Rappersberger K, Schmitt-Egenolf M, Stingl G, Maurer D. 1999. Survival, maturation, and function of CD11c− and CD11c+ peripheral blood dendritic cells are differentially regulated by cytokines. J Immunol. 163: 3250–3259. [PUBMED], [INFOTRIEVE]
  • Kubota R, Umehara F, Izumo S, Ijichi S, Matsumuro K, Yashiki S, Fujiyoshi T, Sonoda S, Osame M. 1994. HTLV-I proviral DNA amount correlates with infiltrating CD4+ lymphocytes in the spinal cord from patients with HTLV-I-associated myelopathy. J Neuroimmunol. 53: 23–29. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Lenzmeier B A, Giebler H A, Nyborg J K. 1998. Human T-cell leukemia virus type 1 Tax requires direct access to DNA for recruitment of CREB binding protein to the viral promoter. Mol Cell Biol. 18: 721–731. [PUBMED], [INFOTRIEVE]
  • Levin M C, Jacobson S. 1997. HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP): a chronic progressive neurologic disease associated with immunologically mediated damage to the central nervous system. J NeuroVirol. 3: 126–140. [PUBMED], [INFOTRIEVE]
  • Li J, Colovai A I, Cortesini R, Suciu-Foca N. 2000. Cloning and functional characterization of the 5′-regulatory region of the human CD86 gene. Hum Immunol. 61: 486–498. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Lindholm P F, Marriott S J, Gitlin S D, Bohan C A, Brady J N. 1990. Induction of nuclear NF-kappa B DNA binding activity after exposure of lymphoid cells to soluble tax1 protein. New Biol. 2: 1034–1043. [PUBMED], [INFOTRIEVE]
  • Lindholm P F, Reid R L, Brady J N. 1992. Extracellular Tax1 protein stimulates tumor necrosis factor-beta and immunoglobulin kappa light chain expression in lymphoid cells. J Virol. 66: 1294–1302. [PUBMED], [INFOTRIEVE]
  • Macatonia S E, Cruickshank J K, Rudge P, Knight S C. 1992. Dendritic cells from patients with tropical spastic paraparesis are infected with HTLV-1 and stimulate autologous lymphocyte proliferation. AIDS Res Hum Retroviruses. 8: 1699–1706. [PUBMED], [INFOTRIEVE]
  • MacKay V L, Moore E E. 1997; Immortalized dendritic cells, US Patent and Trademark Office. ZymoGenetics, Inc, USA
  • Makino M, Shimokubo S, Wakamatsu S I, Izumo S, Baba M. 1999. The role of human T-lymphotropic virus type 1 (HTLV-1)-infected dendritic cells in the development of HTLV-1-associated myelopathy/tropical spastic paraparesis. J Virol. 73: 4575–4581. [PUBMED], [INFOTRIEVE]
  • Marriott S J, Lindholm P F, Reid R L, Brady J N. 1991. Soluble HTLV-I Tax1 protein stimulates proliferation of human peripheral blood lymphocytes. New Biol. 3: 678–686. [PUBMED], [INFOTRIEVE]
  • Marriott S J, Trinh D, Brady J N. 1992. Activation of interleukin-2 receptor alpha expression by extracellular HTLV-I Tax1 protein: a potential role in HTLV-I pathogenesis. Oncogene. 7: 1749–1755. [PUBMED], [INFOTRIEVE]
  • Morel Y, Truneh A, Sweet R W, Olive D, Costello R T. 2001. The TNF superfamily members LIGHT and CD154 (CD40 ligand) costimulate induction of dendritic cell maturation and elicit specific CTL activity. J Immunol. 167: 2479–2486. [PUBMED], [INFOTRIEVE]
  • Moritoyo T, Izumo S, Moritoyo H, Tanaka Y, Kiyomatsu Y, Nagai M, Usuku K, Sorimachi M, Osame M. 1999. Detection of human T-lymphotropic virus type I p40tax protein in cerebrospinal fluid cells from patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. J NeuroVirol. 5: 241–248. [PUBMED], [INFOTRIEVE]
  • Moritoyo T, Reinhart T A, Moritoyo H, Sato E, Izumo S, Osame M, Haase A T. 1996. Human T-lymphotropic virus type I-associated myelopathy and tax gene expression in CD4+ T lymphocytes. Ann Neurol. 40: 84–90. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Nagai M, Brennan M B, Sakai J A, Mora C A, Jacobson S. 2001. CD8(+) T cells are an in vivo reservoir for human T-cell lymphotropic virus type I. Blood. 98: 1858–1861. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Rescigno M, Granucci F, Citterio S, Foti M, Ricciardi-Castagnoli P. 1999. Coordinated events during bacteria-induced DC maturation. Immunol Today. 20: 200–203. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Schonbeck U, Libby P. 2001. The CD40/CD154 receptor/ligand dyad. Cell Mol Life Sci. 58: 4–43. [PUBMED], [INFOTRIEVE]
  • Shaw J P, Utz P J, Durand D B, Toole J J, Emmel E A, Crabtree G R. 1988. Identification of a putative regulator of early T cell activation genes. Science. 241: 202–205. [PUBMED], [INFOTRIEVE]
  • Tillmann M, Wessner R, Wigdahl B. 1994. Identification of human T-cell lymphotropic virus type I 21-base-pair repeat-specific and glial cell-specific DNA-protein complexes. J Virol. 68: 4597–4608. [PUBMED], [INFOTRIEVE]
  • Tillmann M, Wigdahl B. 1994. Identification of HTLV-I 21 bp repeat-specific DNA-protein complexes. Leukemia. 8(Suppl 1)S83–S87. [PUBMED], [INFOTRIEVE]
  • Tureci O, Bian H, Nestle F O, Raddrizzani L, Rosinski J A, Tassis A, Hilton H, Walstead M, Sahin U, Hammer J. 2003. Cascades of transcriptional induction during dendritic cell maturation revealed by genome-wide expression analysis. FASEB J. 17: 836–847. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Uchiyama T. 1997. Human T cell leukemia virus type I (HTLV-I) and human diseases. Annu Rev Immunol. 15: 15–37. [PUBMED], [INFOTRIEVE]
  • Umehara F, Izumo S, Nakagawa M, Ronquillo A T, Takahashi K, Matsumuro K, Sato E, Osame M. 1993. Immunocytochemical analysis of the cellular infiltrate in the spinal cord lesions in HTLV-I-associated myelopathy. J Neuropathol Exp Neurol. 52: 424–430. [PUBMED], [INFOTRIEVE]
  • Verhasselt V, Buelens C, Willems F, De, Groote D, Haeffner-Cavaillon N, Goldman M. 1997. Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. J Immunol. 158: 2919–2925. [PUBMED], [INFOTRIEVE]
  • Wesemann D R, Dong Y, O'Keefe G M, Nguyen V T, Benveniste E N. 2002. Suppressor of cytokine signaling 1 inhibits cytokine induction of CD40 expression in macrophages. J Immunol. 169: 2354–2360. [PUBMED], [INFOTRIEVE]
  • Wessner R, Tillmann-Bogush M, Wigdahl B. 1995. Characterization of a glial cell-specific DNA-protein complex formed with the human T cell lymphotropic virus type I (HTLV-I) enhancer. J NeuroVirol. 1: 62–77. [PUBMED], [INFOTRIEVE]
  • Wessner R, Wigdahl B. 1997. AP-1 derived from mature monocytes and astrocytes preferentially interacts with the HTLV-I promoter central 21 bp repeat. Leukemia. 11(Suppl 3)21–24. [PUBMED], [INFOTRIEVE]
  • Wessner R, Yao J, Wigdahl B. 1997. Sp family members preferentially interact with the promoter proximal repeat within the HTLV-I enhancer. Leukemia. 11(Suppl 3)10–13. [PUBMED], [INFOTRIEVE]
  • Wigdahl B, Brady J N. 1996. Molecular aspects of HTLV-I: relationship to neurological diseases. J NeuroVirol. 2: 307–322. [PUBMED], [INFOTRIEVE]
  • Williams M A, Trout R, Spector S A. 2002. HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells. J Hematother Stem Cell Res. 11: 829–847. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Winzler C, Rovere P, Rescigno M, Granucci F, Penna G, Adorini L, Zimmermann V S, Davoust J, Ricciardi-Castagnoli P. 1997. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J Exp Med. 185: 317–328. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Yamada M, Watabe K, Saida T, Kim S U. 1991. Increased susceptibility of human fetal astrocytes to human T-lymphotropic virus type I in culture. J Neuropathol Exp Neurol. 50: 97–107. [PUBMED], [INFOTRIEVE]
  • Yao J, Wigdahl B. 2000. Human T cell lymphotropic virus type I genomic expression and impact on intracellular signaling pathways during neurodegenerative disease and leukemia. Front Biosci. 5: D138–D168. [PUBMED], [INFOTRIEVE]
  • Zhao J, Freeman G J, Gray G S, Nadler L M, Glimcher L H. 1996. A cell type-specific enhancer in the human B7.1 gene regulated by NF-kappaB. J Exp Med. 183: 777–789. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Zhao L J, Giam C Z. 1992. Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction. Proc Natl Acad Sci U S A. 89: 7070–7074. [PUBMED], [INFOTRIEVE]

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