REFERENCES
- Adamson D C, Kopnisky K L, Dawson T M, Dawson V L. Mechanisms and structural determinants of HIV-1 coat protein, gp41-induced neurotoxicity. J Neurosci 1999; 19: 64–71, [PUBMED], [INFOTRIEVE]
- Adamson D C, Wildemann B, Sasaki M, Glass J D, McArthur J C, Christov V I, Dawson T M, Dawson V L. Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41. Science 1996; 274: 1917–1921, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Addo M M, Altfeld M, Rathod A, Yu M, Yu X G, Goulder P J, Rosenberg E S, Walker B D. HIV-1 Vpu represents a minor target for cytotoxic T lymphocytes in HIV-1 infection. AIDS 2002; 16: 1071–1073, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Agnarsdottir G, Thorsteinsdottir H, Oskarsson T, Matthiasdottir S, St Haflidadottir B, Andresson O S, Andresdottir V. The long terminal repeat is a determinant of cell tropism of maedi- visna virus. J Gen Virol 2000; 81(Pt 8)1901–1905, [PUBMED], [INFOTRIEVE], [CSA]
- Ait-Khaled M, McLaughlin J E, Johnson M A, Emery V C. Distinct HIV-1 long terminal repeat quasispecies present in nervous tissues compared to that in lung, blood and lymphoid tissues of an AIDS patient. AIDS 1995; 9: 675–683, [PUBMED], [INFOTRIEVE]
- Albright A V, Shieh J T, Itoh T, Lee B, Pleasure D, O'Connor M J, Doms R W, Gonzalez-Scarano F. Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates. J Virol 1999; 73: 205–213, [PUBMED], [INFOTRIEVE], [CSA]
- Altfeld M, Addo M M, Eldridge R L, Yu X G, Thomas S, Khatri A, Strick D, Phillips M N, Cohen G B, Islam S A, Kalams S A, Brander C, Goulder P J, Rosenberg E S, Walker B D. Vpr is preferentially targeted by CTL during HIV-1 infection. J Immunol 2001; 167: 2743–2752
- Altfeld M, Allen T M, Yu X G, Johnston M N, Agrawal D, Korber B T, Montefiori D C, O'Connor D H, Davis B T, Lee P K, Maier E L, Harlow J, Goulder P J, Brander C, Rosenberg E S, Walker B D. HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus. Nature 2002; 420: 434–439, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Andresdottir V, Tang X, Agnarsdottir G, Andresson O S, Georgsson G, Skraban R, Torsteinsdottir S, Rafnar B, Benediktsdottir E, Matthiasdottir S, Arnadottir S, Hognadottir S, Palsson P A, Petursson G. Biological and genetic differences between lung- and brain-derived isolates of maedi-visna virus. Virus Genes 1998; 16: 281–293, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Bagasra O, Lavi E, Bobroski L, Khalili K, Pestaner J P, Tawadros R, Pomerantz R J. Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry. AIDS 1996; 10: 573–585, [PUBMED], [INFOTRIEVE]
- Ball J K, Holmes E C, Whitwell H, Desselberger U. Genomic variation of human immunodeficiency virus type 1 (HIV-1): molecular analyses of HIV-1 in sequential blood samples and various organs obtained at autopsy. J Gen Virol 1994; 75: 67–79, [PUBMED], [INFOTRIEVE]
- Barks J D, Liu X H, Sun R, Silverstein F S. gp120, a human immunodeficiency virus-1 coat protein, augments excitotoxic hippocampal injury in perinatal rats. Neuroscience 1997; 76: 397–409, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Barouch D H, Kunstman J, Kuroda M J, Schmitz J E, Santra S, Peyerl F W, Krivulka G R, Beaudry K, Lifton M A, Gorgone D A, Montefiori D C, Lewis M G, Wolinsky S M, Letvin N L. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature 2002; 415: 335–339, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Beilke M A, Minagawa H, Stone G, Leon-Monzon M, Gibbs C J, Jr. Neutralizing antibody responses in patients with AIDS with neurologic complications. J Lab Clin Med 1991; 118: 585–588, [PUBMED], [INFOTRIEVE]
- Bell J E, Busuttil A, Ironside J W, Rebus S, Donaldson Y K, Simmonds P, Peutherer J F. Human immunodeficiency virus and the brain: investigation of virus load and neuropathologic changes in pre-AIDS subjects. J Infect Dis 1993; 168: 818–824, [PUBMED], [INFOTRIEVE]
- Berger E A, Murphy P M, Farber J M. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu Rev Immunol 1999; 17: 657–700, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Berger J R, Nath A, Greenberg R N, Andersen A H, Greene R A, Bognar A, Avison M J. Cerebrovascular changes in the basal ganglia with HIV dementia. Neurology 2000; 54: 921–926, [PUBMED], [INFOTRIEVE], [CSA]
- Berrada F, Ma D, Michaud J, Doucet G, Giroux L, Kessous-Elbaz A. Neuronal expression of human immunodeficiency virus type 1 Env proteins in transgenic mice: distribution in the central nervous system and pathological alterations. J Virol 1995; 69: 6770–6778, [PUBMED], [INFOTRIEVE], [CSA]
- Blackard J T, Cohen D E, Mayer K H. Human immunodeficiency virus superinfection and recombination: Current state of knowledge and potential clinical consequences. Clin Infect Dis 2002; 34: 1108–1114, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Brack-Werner R, Kleinschmidt A, Ludvigsen A, Mellert W, Neumann M, Herrmann R, Khim M C, Burny A, Muller-Lantzsch N, Stavrou D, et al. Infection of human brain cells by HIV-1: restricted virus production in chronically infected human glial cell lines. AIDS 1992; 6: 273–285, [PUBMED], [INFOTRIEVE]
- Bratanich A C, Liu C, McArthur J C, Fudyk T, Glass J D, Mittoo S, Klassen G A, Power C. Brain-derived HIV-1 tat sequences from AIDS patients with dementia show increased molecular heterogeneity. J NeuroVirol 1998; 4: 387–393, [PUBMED], [INFOTRIEVE], [CSA]
- Brew B J, Dore G. Decreasing incidence of CNS AIDS defining events associated with antiretroviral therapy. Neurology 2000; 55: 1424, [PUBMED], [INFOTRIEVE], [CSA]
- Brew B J, Rosenblum M, Cronin K, Price R W. AIDS dementia complex and HIV-1 brain infection: Clinical-virological correlations. Ann Neurol 1995; 38: 563–570, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Brown A J, Cleland A. Independent evolution of the env and pol genes of HIV-1 during zidovudine therapy. AIDS 1996; 10: 1067–1073, [PUBMED], [INFOTRIEVE]
- Buch S, Pinson D, Hou Y, Adany I, Li Z, Mukherjee S, Jia F, Mackay G, Silverstein P, Kumar A, Narayan O. Neuropathogenesis of chimeric simian human immunodeficiency virus infection in rhesus macaques. J Med Primatol 2000; 29: 96–106, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Bukrinsky M I, Sharova N, Dempsey M P, Stanwick T L, Bukrinskaya A G, Haggerty S, Stevenson M. Active nuclear import of human immunodeficiency virus type 1 preintegration complexes. Proc Natl Acad Sci U S A 1992; 89: 6580–6584, [PUBMED], [INFOTRIEVE], [CSA]
- Burudi E M, Marcondes M C, Watry D D, Zandonatti M, Taffe M A, Fox H S. Regulation of indoleamine 2,3-dioxygenase expression in simian immunodeficiency virus-infected monkey brains. J Virol 2002; 76: 12233–12241, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Cara A, Vargas J, Jr, Keller M, Jones S, Mosoian A, Gurtman A, Cohen A, Parkas V, Wallach F, Chusid E, Gelman I H, Klotman M E. Circular viral DNA and anomalous junction sequence in PBMC of HIV- infected individuals with no detectable plasma HIV RNA. Virology 2002; 292: 1–5, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Carotenuto P, Looij D, Keldermans L, deWolf F, Goudsmit J. Neutralizing antibodies are positively associated with CD4+ T-cell counts and T-cell function in long-term AIDS-free infection. AIDS 1998; 12: 1591–1600, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Carrington M, Dean M, Martin M P, O'Brien S J. Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences. Hum Mol Genet 1999a; 8: 1939–1945, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Carrington M, Nelson G W, Martin M P, Kissner T, Vlahov D, Goedert J J, Kaslow R, Buchbinder S, Hoots K, O'Brien S J. HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage. Science 1999b; 283: 1748–1752, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Cecilia D, Kleeberger C, Munoz A, Giorgi J V, Zolla-Pazner S. A longitudinal study of neutralizing antibodies and disease progression in HIV-1-infected subjects. J Infect Dis 1999; 179: 1365–1374, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Chan S Y, Speck R F, Power C, Gaffen S L, Chesebro B, Goldsmith M A. V3 recombinants indicate a central role for CCR5 as a coreceptor in tissue infection by human immunodeficiency virus type 1. J Virol 1999; 73: 2350–2358, [PUBMED], [INFOTRIEVE], [CSA]
- Chang J, Jozwiak R, Wang B, Ng T, Ge Y C, Bolton W, Dwyer D E, Randle C, Osborn R, Cunningham A L, Saksena N K. Unique HIV type 1 V3 region sequences derived from six different regions of brain: region-specific evolution within host-determined quasispecies. AIDS Res Hum Retroviruses 1998; 14: 25–30, [PUBMED], [INFOTRIEVE], [CSA]
- Chen P, Flory E, Avots A, Jordan B W, Kirchhoff F, Ludwig S, Rapp U R. Transactivation of naturally occurring HIV-1 long terminal repeats by the JNK signaling pathway. The most frequent naturally occurring length polymorphism sequence introduces a novel binding site for AP-1 factors. J Biol Chem 2000; 275: 20382–20390, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Cheng J, Nath A, Knudsen B, Hochman S, Geiger J D, Ma M, Magnuson D S. Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein. Neuroscience 1998; 82: 97–106, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Chiao C, Bader T, Stenger J E, Baldwin W, Brady J, Barrett J C. HIV type 1 Tat inhibits tumor necrosis factor α -induced repression of tumor necrosis factor receptor p55 and amplifies tumor necrosis factor α activity in stably tat-transfected HeLa Cells. AIDS Res Hum Retroviruses 2001; 17: 1125–1132, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Cho M W, Lee M K, Carney M C, Berson J F, Doms R W, Martin M A. Identification of determinants on a dualtropic human immunodeficiency virus type 1 envelope glycoprotein that confer usage of CXCR4. J Virol 1998; 72: 2509–2515, [PUBMED], [INFOTRIEVE], [CSA]
- Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath P D, Wu L, Mackay C R, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J. The β -chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 1996; 85: 1135–1148, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Clayton F, Kotler D P, Kuwada S K, Morgan T, Stepan C, Kuang J, Le J, Fantini J. Gp120-induced Bob/GPR15 activation: a possible cause of human immunodeficiency virus enteropathy. Am J Pathol 2001; 159: 1933–1939, [PUBMED], [INFOTRIEVE]
- Clements J E, Zink M C. Molecular biology and pathogenesis of animal lentivirus infections. Clin Microbiol Rev 1996; 9: 100–117, [PUBMED], [INFOTRIEVE], [CSA]
- Coffin J M. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 1995; 267: 483–489, [PUBMED], [INFOTRIEVE]
- Collman R, Balliet J W, Gregory S A, Friedman H M, Kolson D L, Nathanson N, Srinivasan A. An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J Virol 1992; 66: 7517–7521, [PUBMED], [INFOTRIEVE], [CSA]
- Conant K, Garzino-Demo A, Nath A, McArthur J C, Halliday W, Power C, Gallo R C, Major E O. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proc Natl Acad Sci U S A 1998; 95: 3117–3121, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Corboy J R, Buzy J M, Zink M C, Clements J E. Expression directed from HIV long terminal repeats in the central nervous system of transgenic mice. Science 1992; 258: 1804–1808, [PUBMED], [INFOTRIEVE]
- Corboy J R, Garl P J. HIV-1 LTR DNA sequence variation in brain-derived isolates. J NeuroVirol 1997; 3: 331–341, [PUBMED], [INFOTRIEVE], [CSA]
- Corder E H, Robertson K, Lannfelt L, Bogdanovic N, Eggertsen G, Wilkins J, Hall C. HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy. Nat Med 1998; 4: 1182–1184, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Davis L E, Hjelle B L, Miller V E, Palmer D L, Llewellyn A L, Merlin T L, Young S A, Mills R G, Wachsman W, Wiley C A. Early viral brain invasion in iatrogenic human immunodeficiency virus infection. Neurology 1992; 42: 1736–1739, [PUBMED], [INFOTRIEVE]
- De Luca A, Ciancio B C, Larussa D, Murri R, Cingolani A, Rizzo M G, Giancola M L, Ammassari A, Ortona L. Correlates of independent HIV-1 replication in the CNS and of its control by antiretrovirals. Neurology 2002; 59: 342–347, [PUBMED], [INFOTRIEVE], [CSA]
- Dean M, Carrington M, O'Brien S J. Balanced polymorphism selected by genetic versus infectious human disease. Annu Rev Genomics Hum Genet 2002; 3: 263–292, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- De Fillipis V R, Villarreal L P. Virus Evolution. Fields virology, D M Knipe, P M Howley. Lippincott Williams & Wilkins, Philadelphia 2001; pp 353–370
- Demuth M, Czub S, Sauer U, Koutsilieri E, Haaft P, Heeney J, Stahl-Hennig C, terMeulen V, Sopper S. Relationship between viral load in blood, cerebrospinal fluid, brain tissue and isolated microglia with neurological disease in macaques infected with different strains of SIV. J NeuroVirol 2000; 6: 187–201, [PUBMED], [INFOTRIEVE], [CSA]
- Domingo E, Holland J J. Origin and evolution of viruses. Academic Press., New York 1999
- Doranz B J, Rucker J, Yi Y, Smyth R J, Samson M, Peiper S C, Parmentier M, Collman R G, Doms R W. A dual-tropic primary HIV-1 isolate that uses fusin and the β -chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 1996; 85: 1149–1158, [PUBMED], [INFOTRIEVE]
- Dore G J, Correll P K, Li Y, Kaldor J M, Cooper D A, Brew B J. Changes to AIDS dementia complex in the era of highly active antiretroviral therapy. AIDS 1999; 13: 1249–1253, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Dreyer E B, Kaiser P K, Offermann J T, Lipton S A. HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. Science 1990; 248: 364–367, [PUBMED], [INFOTRIEVE]
- Eggers C, Stuerenburg H J, Schafft T, Zollner B, Feucht H H, Stellbrink H J, vanLunzen J. Rapid clearance of human immunodeficiency virus type 1 from ventricular cerebrospinal fluid during antiretroviral treatment. Ann Neurol 2000; 47: 816–819, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Eigen M. Self-organization of matter and evolution of biological macromolecules. Naturwissenschaften 1971; 58: 465–523, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Eigen M, Biebricher C K. Sequence space and quasispecies distribution. RNA genetics, E Domingo, J J Holland, P Ahlquist. CRC Press, Boca Raton, FL 1988; pp 211–245
- Ellis R J, Gamst A C, Capparelli E, Spector S A, Hsia K, Wolfson T, Abramson I, Grant I, McCutchan J A. Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources. Neurology 2000; 54: 927–936, [PUBMED], [INFOTRIEVE], [CSA]
- Ellis R J, Hsia K, Spector S A, Nelson J A, Heaton R K, Wallace M R, Abramson I, Atkinson J H, Grant I, McCutchan J A. Cerebrospinal fluid human immunodeficiency virus type 1 RNA levels are elevated in neurocognitively impaired individuals with acquired immunodeficiency syndrome. HIV Neurobehavioral Research Center Group. Ann Neurol 1997; 42: 679–688, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Estable M C, Bell B, Hirst M, Sadowski I. Naturally occurring human immunodeficiency virus type 1 long terminal repeats have a frequently observed duplication that binds RBF-2 and represses transcription. J Virol 1998; 72: 6465–6474, [PUBMED], [INFOTRIEVE], [CSA]
- Estable M C, Bell B, Merzouki A, Montaner J S, O'Shaughnessy M V, Sadowski I J. Human immunodeficiency virus type 1 long terminal repeat variants from 42 patients representing all stages of infection display a wide range of sequence polymorphism and transcription activity. J Virol 1996; 70: 4053–4062, [PUBMED], [INFOTRIEVE], [CSA]
- Evans D T, O'Connor D H, Jing P, Dzuris J L, Sidney J, daSilva J, Allen T M, Horton H, Venham J E, Rudersdorf R A, Vogel T, Pauza C D, Bontrop R E, DeMars R, Sette A, Hughes A L, Watkins D I. Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef. Nat Med 1999; 5: 1270–1276, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Fang G, Zhu G, Burger H, Keithly J S, Weiser B. Minimizing DNA recombination during long RT-PCR. J Virol Methods 1998; 76: 139–148, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Fawell S, Seery J, Daikh Y, Moore C, Chen L L, Pepinsky B, Barsoum J. Tat-mediated delivery of heterologous proteins into cells. Proc Natl Acad Sci U S A 1994; 91: 664–668, [PUBMED], [INFOTRIEVE], [CSA]
- Flynn G, Maru S, Loughlin J, Romero I A, Male D. Regulation of chemokine receptor expression in human microglia and astrocytes. J Neuroimmunol 2003; 136: 84–93, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Freed E O, Martin M A. HIVs and their replication. Fields virology, D M Knipe, P M Howley. Lippincott Williams & Wilkins, Philadelphia 2001; pp 1971–2041
- Frost S D, Gunthard H F, Wong J K, Havlir D, Richman D D, LeighBrown A J. Evidence for positive selection driving the evolution of HIV-1 env under potent antiviral therapy. Virology 2001; 284: 250–258, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Gabuzda D, Wang J. Chemokine receptors and mechanisms of cell death in HIV neuropathogenesis. J NeuroVirol 2000; 6(Suppl 1)S24–S32, [PUBMED], [INFOTRIEVE]
- Garcia F, Plana M, Ortiz G M, Bonhoeffer S, Soriano A, Vidal C, Cruceta A, Arnedo M, Gil C, Pantaleo G, Pumarola T, Gallart T, Nixon D F, Miro J M, Gatell J M. The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection. AIDS 2001; 15: F29–F40, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Garden G A. Microglia in human immunodeficiency virus-associated neurodegeneration. Glia 2002; 40: 240–251, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Gaschen B, Taylor J, Yusim K, Foley B, Gao F, Lang D, Novitsky V, Haynes B, Hahn B H, Bhattacharya T, Korber B. Diversity considerations in HIV-1 vaccine selection. Science 2002; 296: 2354–2360, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Gatanaga H, Oka S, Ida S, Wakabayashi T, Shioda T, Iwamoto A. Active HIV-1 redistribution and replication in the brain with HIV encephalitis. Arch Virol 1999; 144: 29–43, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Gemma C, Smith E M, Hughes T K, Jr, Opp M R. Human immunodeficiency virus glycoprotein 160 induces cytokine mRNA expression in the rat central nervous system. Cell Mol Neurobiol 2000; 20: 419–431, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ghezzi S, Noonan D M, Aluigi M G, Vallanti G, Cota M, Benelli R, Morini M, Reeves J D, Vicenzi E, Poli G, Albini A. Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat. Biochem Biophys Res Commun 2000; 270: 992–996, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Gonzalez E, Rovin B H, Sen L, Cooke G, Dhanda R, Mummidi S, Kulkarni H, Bamshad M J, Telles V, Anderson S A, Walter E A, Stephan K T, Deucher M, Mangano A, Bologna R, Ahuja S S, Dolan M J, Ahuja S K. HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels. Proc Natl Acad Sci U S A 2002; 99: 13795–13800, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Gorry P R, Bristol G, Zack J A, Ritola K, Swanstrom R, Birch C J, Bell J E, Bannert N, Crawford K, Wang H, Schols D, De Clercq E, Kunstman K, Wolinsky S M, Gabuzda D. Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity. J Virol 2001; 75: 10073–10089, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Gorry P R, Howard J L, Churchill M J, Anderson J L, Cunningham A, Adrian D, McPhee D A, Purcell D F. Diminished production of human immunodeficiency virus type 1 in astrocytes results from inefficient translation of gag, env, and nef mRNAs despite efficient expression of Tat and Rev. J Virol 1999; 73: 352–361, [PUBMED], [INFOTRIEVE], [CSA]
- Gorry P R, Taylor J, Holm G H, Mehle A, Morgan T, Cayabyab M, Farzan M, Wang H, Bell J E, Kunstman K, Moore J P, Wolinsky S M, Gabuzda D. Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate. J Virol 2002; 76: 6277–6292, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Gottlieb G S, Nickle D C, Jensen M A, Wong K G, Grobler J, Li F, Liu S L, Rademeyer C, Learn G H, Karim S S, Williamson C, Corey L, Margolick J B, Mullins J I. Dual HIV-1 infection associated with rapid disease progression. Lancet 2004; 363: 619–622, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Goulder P J, Altfeld M A, Rosenberg E S, Nguyen T, Tang Y, Eldridge R L, Addo M M, He S, Mukherjee J S, Phillips M N, Bunce M, Kalams S A, Sekaly R P, Walker B D, Brander C. Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection. J Exp Med 2001; 193: 181–194, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Goulder P J, Walker B D. The great escape—AIDS viruses and immune control. Nat Med 1999; 5: 1233–1235, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Grant R S, Naif H, Thuruthyil S J, Nasr N, Littlejohn T, Takikawa O, Kapoor V. Induction of indoleamine 2,3-dioxygenase in primary human macrophages by HIV-1. Redox Rep 2000; 5: 105–107, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Gruol D L, Yu N, Parsons K L, Billaud J N, Elder J H, Phillips T R. Neurotoxic effects of feline immunodeficiency virus, FIV-PPR. J NeuroVirol 1998; 4: 415–425, [PUBMED], [INFOTRIEVE], [CSA]
- Hannibal M C, Markovitz D M, Clark N, Nabel G J. Differential activation of human immunodeficiency virus type 1 and 2 transcription by specific T-cell activation signals. J Virol 1993; 67: 5035–5040, [PUBMED], [INFOTRIEVE], [CSA]
- Hasenkrug K J, Robertson S J, Porti J, McAtee F, Nishio J, Chesebro B. Two separate envelope regions influence induction of brain disease by a polytropic murine retrovirus (FMCF98). J Virol 1996; 70: 4825–4828, [PUBMED], [INFOTRIEVE], [CSA]
- He J, Chen Y, Farzan M, Choe H, Ohagen A, Gartner S, Busciglio J, Yang X, Hofmann W, Newman W, Mackay C R, Sodroski J, Gabuzda D. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 1997; 385: 645–649, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Henderson A J, Connor R I, Calame K L. C/EBP activators are required for HIV-1 replication and proviral induction in monocytic cell lines. Immunity 1996; 5: 91–101, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Henderson A J, Zou X, Calame K L. C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes. J Virol 1995; 69: 5337–5344, [PUBMED], [INFOTRIEVE], [CSA]
- Hiebenthal-Millow K, Kirchhoff F. The most frequent naturally occurring length polymorphism in the HIV-1 LTR has little effect on proviral transcription and viral replication. Virology 2002; 292: 169–175, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Hoffman T L, Stephens E B, Narayan O, Doms R W. HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors. Proc Natl Acad Sci U S A 1998; 95: 11360–11365, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Hogan T H, Krebs F C, Wigdahl B. Regulation of human immunodeficiency virus type 1 gene expression and pathogenesis by CCAAT/enhancer binding proteins in cells of the monocyte/macrophage lineage. J NeuroVirol 2002; 8: 21–26, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Hogan T H, Stauff D L, Krebs F C, Gartner S, Quiterio S J, Wigdahl B. Structural and functional evolution of human immunodeficiency virus type 1 long terminal repeat CCAAT/enhancer binding protein sites and their use as molecular markers for central nervous system disease progression. J NeuroVirol 2003; 9: 55–68, [PUBMED], [INFOTRIEVE], [CSA]
- Holmes C, El-Okl M, Williams A L, Cunningham C, Wilcockson D, Perry V H. Systemic infection, interleukin 1β and cognitive decline in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2003; 74: 788–789, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Huang K J, Alter G M, Wooley D P. The reverse transcriptase sequence of human immunodeficiency virus type 1 is under positive evolutionary selection within the central nervous system. J NeuroVirol 2002; 8: 281–294, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Hudson L, Liu J, Nath A, Jones M, Raghavan R, Narayan O, Male D, Everall I. Detection of the human immunodeficiency virus regulatory protein Tat in CNS tissues. J NeuroVirol 2000; 6: 145–155, [PUBMED], [INFOTRIEVE], [CSA]
- Hughes E S, Bell J E, Simmonds P. Investigation of the dynamics of the spread of human immunodeficiency virus to brain and other tissues by evolutionary analysis of sequences from the p17gag and env genes. J Virol 1997; 71: 1272–1280, [PUBMED], [INFOTRIEVE], [CSA]
- Janssen R S, Nwanyanwu O C, Selik R M, Stehr-Green J K. Epidemiology of human immunodeficiency virus encephalopathy in the United States. Neurology 1992; 42: 1472–1476, [PUBMED], [INFOTRIEVE]
- Jeeninga R E, Hoogenkamp M, Armand-Ugon M, deBaar M, Verhoef K, Berkhout B. Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G. J Virol 2000; 74: 3740–3751, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Johnson R T. Viral infections of the nervous system2nd ed. Lippincott-Raven, Philadelphia 1998
- Johnson R T, Glass J D, McArthur J C, Chesebro B W. Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndrome. Ann Neurol 1996; 39: 392–395, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Johnston J B, Jiang Y, vanMarle G, Mayne M B, Ni W, Holden J, McArthur J C, Power C. Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity. J Virol 2000; 74: 7211–7220, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Johnston J B, Silva C, Hiebert T, Buist R, Dawood M R, Peeling J, Power C. Neurovirulence depends on virus input titer in brain in feline immunodeficiency virus infection: evidence for activation of innate immunity and neuronal injury. J NeuroVirol 2002a; 8: 420–431, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Johnston J B, Silva C, Power C. Envelope gene-mediated neurovirulence in feline immunodeficiency virus infection: induction of matrix metalloproteinases and neuronal injury. J Virol 2002b; 76: 2622–2633, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Johnston J B, Zhang K, Silva C, Shalinsky D R, Conant K, Ni W, Corbett D, Yong V W, Power C. HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors. Ann Neurol 2001; 49: 230–241, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Jones M, Olafson K, DelBigio M R, Peeling J, Nath A. Intraventricular injection of human immunodeficiency virus type 1 (HIV- 1) Tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement. J Neuropathol Exp Neurol 1998; 57: 563–570, [PUBMED], [INFOTRIEVE], [CSA]
- Jordan-Sciutto K L, Wang G, Murphy-Corb M, Wiley C A. Induction of cell-cycle regulators in simian immunodeficiency virus encephalitis. Am J Pathol 2000; 157: 497–507, [PUBMED], [INFOTRIEVE]
- Jost S, Bernard M C, Kaiser L, Yerly S, Hirschel B, Samri A, Autran B, Goh L E, Perrin L. A patient with HIV-1 superinfection. N Engl J Med 2002; 347: 731–736, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Kaiser P K, Offermann J T, Lipton S A. Neuronal injury due to HIV-1 envelope protein is blocked by anti-gp120 antibodies but not by anti-CD4 antibodies. Neurology 1990; 40: 1757–1761, [PUBMED], [INFOTRIEVE]
- Kamps C A, Lin Y C, Wong P K. Oligomerization and transport of the envelope protein of Moloney murine leukemia virus-TB and of ts1, a neurovirulent temperature-sensitive mutant of MoMuLV-TB. Virology 1991; 184: 687–694, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Kanki P J, Hamel D J, Sankale J L, Hsieh C, Thior I, Barin F, Woodcock S A, Gueye-Ndiaye A, Zhang E, Montano M, Siby T, Marlink R, I N D, Essex M E, S M B. Human immunodeficiency virus type 1 subtypes differ in disease progression. J Infect Dis 1999; 179: 68–73, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Kaul M, Garden G A, Lipton S A. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 2001; 410: 988–994, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Keswani S C, Pardo C A, Cherry C L, Hoke A, McArthur J C. HIV-associated sensory neuropathies. AIDS 2002; 16: 2105–2117, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Khanna K V, Yu X F, Ford D H, Ratner L, Hildreth J K, Markham R B. Differences among HIV-1 variants in their ability to elicit secretion of TNF-α. J Immunol 2000; 164: 1408–1415, [PUBMED], [INFOTRIEVE]
- Kinter A, Arthos J, Cicala C, Fauci A S. Chemokines, cytokines and HIV: a complex network of interactions that influence HIV pathogenesis. Immunol Rev 2000; 177: 88–98, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Klein R S, Williams K C, Alvarez–Hernandez X, Westmoreland S, Force T, Lackner A A, Luster A D. Chemokine receptor expression and signaling in macaque and human fetal neurons and astrocytes: implications for the neuropathogenesis of AIDS. J Immunol 1999; 163: 1636–1646, [PUBMED], [INFOTRIEVE]
- Koken S E, vanWamel J L, Goudsmit J, Berkhout B, Geelen J L. Natural variants of the HIV-1 long terminal repeat: analysis of promoters with duplicated DNA regulatory motifs. Virology 1992; 191: 968–972, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Kolson D L, Collman R, Hrin R, Balliet J W, Laughlin M, McGann K A, Debouck C, Gonzalez-Scarano F. Human immunodeficiency virus type 1 Tat activity in human neuronal cells: uptake and trans-activation. J Gen Virol 1994; 75: 1927–1934, [PUBMED], [INFOTRIEVE], [CSA]
- Korber B, Gaschen B, Yusim K, Thakallapally R, Kesmir C, Detours V. Evolutionary and immunological implications of contemporary HIV-1 variation. Br Med Bull 2001; 58: 19–42, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Korber B T, Kunstman K J, Patterson B K, Furtado M, McEvilly M M, Levy R, Wolinsky S M. Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain- derived sequences. J Virol 1994; 68: 7467–7481, [PUBMED], [INFOTRIEVE], [CSA]
- Kreisberg J F, Kwa D, Schramm B, Trautner V, Connor R, Schuitemaker H, Mullins J I, van'tWout A B, Goldsmith M A. Cytopathicity of human immunodeficiency virus type 1 primary isolates depends on coreceptor usage and not patient disease status. J Virol 2001; 75: 8842–8847, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Lafrenie R M, Wahl L M, Epstein J S, Hewlett I K, Yamada K M, Dhawan S. HIV-1-Tat modulates the function of monocytes and alters their interactions with microvessel endothelial cells. A mechanism of HIV pathogenesis. J Immunol 1996; 156: 1638–1645, [PUBMED], [INFOTRIEVE]
- Lane T E, Buchmeier M J, Watry D D, Fox H S. Expression of inflammatory cytokines and inducible nitric oxide synthase in brains of SIV-infected rhesus monkeys: applications to HIV- induced central nervous system disease. Mol Med 1996; 2: 27–37, [PUBMED], [INFOTRIEVE]
- Lanier E R, Sturge G, McClernon D, Brown S, Halman M, Sacktor N, McArthur J, Atkinson J H, Clifford D, Price R W, Simpson D, Torres G, Catalan J, Marder K, Power C, Hall C, Romero C, Brew B. HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir. AIDS 2001; 15: 747–751, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Lavreys L, Baeten J M, Overbaugh J, Panteleeff D D, Chohan B H, Richardson B A, Mandaliya K, Ndinya-Achola J O, Kreiss J K. Virus load during primary human immunodeficiency virus (HIV) type 1 infection is related to the severity of acute HIV illness in Kenyan women. Clin Infect Dis 2002; 35: 77–81, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Lazarini F, Seilhean D, Rosenblum O, Suarez S, Conquy L, Uchihara T, Sazdovitch V, Mokhtari K, Maisonobe T, Boussin F, Katlama C, Bricaire F, Duyckaerts C, Hauw J J. Human immunodeficiency virus type 1 DNA and RNA load in brains of demented and nondemented patients with acquired immunodeficiency syndrome. J NeuroVirol 1997; 3: 299–303, [PUBMED], [INFOTRIEVE], [CSA]
- Lipsitch M, Nowak M A, Ebert D, May R M. The population dynamics of vertically and horizontally transmitted parasites. Proc R Soc Lond B Biol Sci 1995; 260: 321–327
- Lipton S A, Gendelman H E. Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome. N Engl J Med 1995; 332: 934–940, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Little S J. Transmission and prevalence of HIV resistance among treatment-naive subjects. Antivir Ther 2000; 5: 33–40, [PUBMED], [INFOTRIEVE], [CSA]
- Little S J, Holte S, Routy J P, Daar E S, Markowitz M, Collier A C, Koup R A, Mellors J W, Connick E, Conway B, Kilby M, Wang L, Whitcomb J M, Hellmann N S, Richman D D. Antiretroviral-drug resistance among patients recently infected with HIV. N Engl J Med 2002; 347: 385–394, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Liu S L, Schacker T, Musey L, Shriner D, McElrath M J, Corey L, Mullins J I. Divergent patterns of progression to AIDS after infection from the same source: human immunodeficiency virus type 1 evolution and antiviral responses. J Virol 1997; 71: 4284–4295, [PUBMED], [INFOTRIEVE], [CSA]
- Liu Y, Tang X P, McArthur J C, Scott J, Gartner S. Analysis of human immunodeficiency virus type 1 gp160 sequences from a patient with HIV dementia: evidence for monocyte trafficking into brain. J NeuroVirol 2000; 6(Suppl 1)S70–S81, [PUBMED], [INFOTRIEVE]
- Loomis-Price L D, Cox J H, Mascola J R, VanCott T C, Michael N L, Fouts T R, Redfield R R, Robb M L, Wahren B, Sheppard H W, Birx D L. Correlation between humoral responses to human immunodeficiency virus type 1 envelope and disease progression in early-stage infection. J Infect Dis 1998; 178: 1306–1316, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Lucas S B, Hounnou A, Peacock C, Beaumel A, Djomand G, N'Gbichi J M, Yeboue K, Honde M, Diomande M, Giordano C, et al. The mortality and pathology of HIV infection in a west African city. AIDS 1993; 7: 1569–1579, [PUBMED], [INFOTRIEVE]
- Lukashov V V, Kuiken C L, Goudsmit J. Intrahost human immunodeficiency virus type 1 evolution is related to length of the immunocompetent period. J Virol 1995; 69: 6911–6916, [PUBMED], [INFOTRIEVE], [CSA]
- Lynch W P, Robertson S J, Portis J L. Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia. J Virol 1995; 69: 1408–1419, [PUBMED], [INFOTRIEVE], [CSA]
- Lynch W P, Sharpe A H. Differential glycosylation of the Cas-Br-E Env protein is associated with retrovirus-induced spongiform neurodegeneration. J Virol 2000; 74: 1558–1565, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Malim M H, Emerman M. HIV-1 sequence variation: drift, shift, and attenuation. Cell 2001; 104: 469–472, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Marcondes M C, Burudi E M, Huitron-Resendiz S, Sanchez-Alavez M, Watry D, Zandonatti M, Henriksen S J, Fox H S. Highly activated CD8(+) T cells in the brain correlate with early central nervous system dysfunction in simian immunodeficiency virus infection. J Immunol 2001; 167: 5429–5438, [PUBMED], [INFOTRIEVE]
- Markham R B, Wang W C, Weisstein A E, Wang Z, Munoz A, Templeton A, Margolick J, Vlahov D, Quinn T, Farzadegan H, Yu X F. Patterns of HIV-1 evolution in individuals with differing rates of CD4 T cell decline. Proc Natl Acad Sci U S A 1998; 95: 12568–12573, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Martin J, LaBranche C C, Gonzalez-Scarano F. Differential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate. J Virol 2001; 75: 3568–3580, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Martin-Garcia J, Kolson D L, Gonzalez-Scarano F. Chemokine receptors in the brain: their role in HIV infection and pathogenesis. AIDS 2002; 16: 1709–1730, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Mayne M, Bratanich A C, Chen P, Rana F, Nath A, Power C. HIV-1 Tat molecular diversity and induction of TNF-α : Implications for HIV-induced neurological disease. Neuroimmunomodulation 1998; 5: 184–192, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- McArthur J C, Hoover D R, Bacellar H, Miller E N, Cohen B A, Becker J T, Graham N M, McArthur J H, Selnes O A, Jacobson L P, et al. Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study. Neurology 1993; 43: 2245–2252, [PUBMED], [INFOTRIEVE], [CSA]
- McArthur J C, McClernon D R, Cronin M F, Nance-Sproson T E, Saah A J, St Clair M, Lanier E R. Relationship between human immunodeficiency virus-associated dementia and viral load in cerebrospinal fluid and brain. Ann Neurol 1997; 42: 689–698, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- McClernon D R, Lanier R, Gartner S, Feaser P, Pardo C A, St Clair M, Liao Q, McArthur J C. HIV in the brain: RNA levels and patterns of zidovudine resistance. Neurology 2001; 57: 1396–1401, [PUBMED], [INFOTRIEVE], [CSA]
- McMichael A J, Rowland-Jones S L. Cellular immune responses to HIV. Nature 2001; 410: 980–987, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Mellors J W, Munoz A, Giorgi J V, Margolick J B, Tassoni C J, Gupta P, Kingsley L A, Todd J A, Saah A J, Detels R, Phair J P, Rinaldo C R, Jr. Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med 1997; 126: 946–954, [PUBMED], [INFOTRIEVE], [CSA]
- Messam C A, Major E O. Stages of restricted HIV-1 infection in astrocyte cultures derived from human fetal brain tissue. J NeuroVirol 2000; 6(Suppl 1)S90–S94, [PUBMED], [INFOTRIEVE]
- Mollace V, Nottet H S, Clayette P, Turco M C, Muscoli C, Salvemini D, Perno C F. Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants. Trends Neurosci 2001; 24: 411–416, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Morris A, Marsden M, Halcrow K, Hughes E S, Brettle R P, Bell J E, Simmonds P. Mosaic structure of the human immunodeficiency virus type 1 genome infecting lymphoid cells and the brain: evidence for frequent in vivo recombination events in the evolution of regional populations. J Virol 1999; 73: 8720–8731, [PUBMED], [INFOTRIEVE], [CSA]
- Munoz-Fernandez M A, Navarro J, Garcia A, Punzon C, Fernandez-Cruz E, Fresno M. Replication of human immunodeficiency virus-1 in primary human T cells is dependent on the autocrine secretion of tumor necrosis factor through the control of nuclear factor-kappa B activation. J Allergy Clin Immunol 1997; 100: 838–845, [PUBMED], [INFOTRIEVE], [CSA]
- Murray E A, Rausch D M, Lendvay J, Sharer L R, Eiden L E. Cognitive and motor impairments associated with SIV infection in rhesus monkeys. Science 1992; 255: 1246–1249, [PUBMED], [INFOTRIEVE]
- Narayan O, Joag S V, Stephens E B. Selected models of HIV-induced neurological disease. Curr Top Microbiol Immunol 1995; 202: 151–166, [PUBMED], [INFOTRIEVE], [CSA]
- Natarajan V, Bosche M, Metcalf J A, Ward D J, Lane H C, Kovacs J A. HIV-1 replication in patients with undetectable plasma virus receiving HAART. Highly active antiretroviral therapy. Lancet 1999; 353: 119–120, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Nath A. Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia. J Infect Dis 2002; 186(Suppl 2)S193–S198, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Nath A, Conant K, Chen P, Scott C, Major E O. Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon. J Biol Chem 1999; 274: 17098–17102, [PUBMED], [INFOTRIEVE]
- Nath A, Psooy K, Martin C, Knudsen B, Magnuson D S, Haughey N, Geiger J D. Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic. J Virol 1996; 70: 1475–1480, [PUBMED], [INFOTRIEVE], [CSA]
- Neilson J R, John G C, Carr J K, Lewis P, Kreiss J K, Jackson S, Nduati R W, Mbori-Ngacha D, Panteleeff D D, Bodrug S, Giachetti C, Bott M A, Richardson B A, Bwayo J, Ndinya-Achola J, Overbaugh J. Subtypes of human immunodeficiency virus type 1 and disease stage among women in Nairobi, Kenya. J Virol 1999; 73: 4393–4403, [PUBMED], [INFOTRIEVE], [CSA]
- Neuenburg J K, Brodt H R, Herndier B G, Bickel M, Bacchetti P, Price R W, Grant R M, Schlote W. HIV-related neuropathology, 1985 to 1999: rising prevalence of HIV encephalopathy in the era of highly active antiretroviral therapy. J Acquir Immune Defic Syndr 2002; 31: 171–177, [PUBMED], [INFOTRIEVE]
- Neumann M, Felber B K, Kleinschmidt A, Froese B, Erfle V, Pavlakis G N, Brack-Werner R. Restriction of human immunodeficiency virus type 1 production in a human astrocytoma cell line is associated with a cellular block in Rev function. J Virol 1995; 69: 2159–2167, [PUBMED], [INFOTRIEVE], [CSA]
- Nguyen M D, D'Aigle T, Gowing G, Julien J P, Rivest S. Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis. J Neurosci 2004; 24: 1340–1349, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Nottet H S, Persidsky Y, Sasseville V G, Nukuna A N, Bock P, Zhai Q H, Sharer L R, McComb R D, Swindells S, Soderland C, Gendelman H E. Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain. J Immunol 1996; 156: 1284–1295, [PUBMED], [INFOTRIEVE]
- Nowak M A, Sigmund K. Evolutionary dynamics of biological games. Science 2004; 303: 793–799, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Nuovo G J, Gallery F, MacConnell P, Braun A. In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-α RNA in the central nervous system. Am J Pathol 1994; 144: 659–666, [PUBMED], [INFOTRIEVE]
- O'Brien S J, Moore J P. The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS. Immunol Rev 2000; 177: 99–111, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ohagen A, Ghosh S, He J, Huang K, Chen Y, Yuan M, Osathanondh R, Gartner S, Shi B, Shaw G, Gabuzda D. Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: evidence for a role of the envelope. J Virol 1999; 73: 897–906, [PUBMED], [INFOTRIEVE], [CSA]
- Overbaugh J, Bangham C R. Selection forces and constraints on retroviral sequence variation. Science 2001; 292: 1106–1109, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Pang S, Koyanagi Y, Miles S, Wiley C, Vinters H V, Chen I S. High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients. Nature 1990; 343: 85–89, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Patel C A, Mukhtar M, Harley S, Kulkosky J, Pomerantz R J. Lentiviral expression of HIV-1 Vpr induces apoptosis in human neurons. J NeuroVirol 2002; 8: 86–99, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Patel C A, Mukhtar M, Pomerantz R J. Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal Cells. J Virol 2000; 74: 9717–9726, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Patrick M K, Johnston J B, Power C. Lentiviral neuropathogenesis: comparative neuroinvasion, neurotropism, neurovirulence, and host neurosusceptibility. J Virol 2002; 76: 7923–7931, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Pattarini R, Pittaluga A, Raiteri M. The human immunodeficiency virus-1 envelope protein gp120 binds through its V3 sequence to the glycine site of N-methyl-D-aspartate receptors mediating noradrenaline release in the hippocampus. Neuroscience 1998; 87: 147–157, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Pauza C D, Trivedi P, McKechnie T S, Richman D D, Graziano F M. 2-LTR circular viral DNA as a marker for human immunodeficiency virus type 1 infection in vivo. Virology 1994; 205: 470–478, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Peruzzi F, Gordon J, Darbinian N, Amini S. Tat-induced deregulation of neuronal differentiation and survival by nerve growth factor pathway. J NeuroVirol 2002; 8: 91–96, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Peterson K E, Robertson S J, Portis J L, Chesebro B. Differences in cytokine and chemokine responses during neurological disease induced by polytropic murine retroviruses Map to separate regions of the viral envelope gene. J Virol 2001; 75: 2848–2856, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Philippon V, Vellutini C, Gambarelli D, Harkiss G, Arbuthnott G, Metzger D, Roubin R, Filippi P. The basic domain of the lentiviral Tat protein is responsible for damages in mouse brain: Involvement of cytokines. Virology 1994; 205: 519–529, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Pierson T, Hoffman T L, Blankson J, Finzi D, Chadwick K, Margolick J B, Buck C, Siliciano J D, Doms R W, Siliciano R F. Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1. J Virol 2000; 74: 7824–7833, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Pilgrim A K, Pantaleo G, Cohen O J, Fink L M, Zhou J Y, Zhou J T, Bolognesi D P, Fauci A S, Montefiori D C. Neutralizing antibody responses to human immunodeficiency virus type 1 in primary infection and long-term-nonprogressive infection. J Infect Dis 1997; 176: 924–932, [PUBMED], [INFOTRIEVE]
- Poli A, Pistello M, Carli M A, Abramo F, Mancuso G, Nicoletti E, Bendinelli M. Tumor necrosis factor-α and virus expression in the central nervous system of cats infected with feline immunodeficiency virus. J NeuroVirol 1999; 5: 465–473, [PUBMED], [INFOTRIEVE], [CSA]
- Poluektova L Y, Munn D H, Persidsky Y, Gendelman H E. Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis. J Immunol 2002; 168: 3941–3949, [PUBMED], [INFOTRIEVE]
- Poulsen D J, Favara C, Snyder E Y, Portis J, Chesebro B. Increased neurovirulence of polytropic mouse retroviruses delivered by inoculation of brain with infected neural stem cells. Virology 1999; 263: 23–29, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Poulsen D J, Robertson S J, Favara C A, Portis J L, Chesebro B W. Mapping of a neurovirulence determinant within the envelope protein of a polytropic murine retrovirus: induction of central nervous system disease by low levels of virus. Virology 1998; 248: 199–207, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Power C, Buist R, Johnston J B, DelBigio M R, Ni W, Dawood M R, Peeling J. Neurovirulence in feline immunodeficiency virus-infected neonatal cats is viral strain specific and dependent on systemic immune suppression. J Virol 1998a; 72: 9109–9115, [PUBMED], [INFOTRIEVE], [CSA]
- Power C, Gill M J, Johnson R T. Progress in clinical neurosciences: the neuropathogenesis of HIV infection: host-virus interaction and the impact of therapy. Can J Neurol Sci 2002; 29: 19–32, [PUBMED], [INFOTRIEVE], [CSA]
- Power C, Johnson R T. Neuroimmune and neurovirological aspects of human immunodeficiency virus infection. Adv Virus Res 2001; 56: 389–433, [PUBMED], [INFOTRIEVE], [CSA]
- Power C, Kong P A, Crawford T O, Wesselingh S, Glass J D, McArthur J C, Trapp B D. Cerebral white matter changes in acquired immunodeficiency syndrome dementia Aalterations of the blood-brain barrier. Ann Neurol 1993; 34: 339–350, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Power C, McArthur J C, Nath A, Wehrly K, Mayne M, Nishio J, Langelier T, Johnson R T, Chesebro B. Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differs between demented and nondemented AIDS patients. J Virol 1998b; 72: 9045–9053, [PUBMED], [INFOTRIEVE], [CSA]
- Price R W, Paxinos E E, Grant R M, Drews B, Nilsson A, Hoh R, Hellmann N S, Petropoulos C J, Deeks S G. Cerebrospinal fluid response to structured treatment interruption after virological failure. AIDS 2001; 15: 1251–1259, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Quasney M W, Zhang Q, Sargent S, Mynatt M, Glass J, McArthur J. Increased frequency of the tumor necrosis factor-α -308 A allele in adults with human immunodeficiency virus dementia. Ann Neurol 2001; 50: 157–162, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Rambaut A, Posada D, Crandall K A, Holmes E C. The causes and consequences of HIV evolution. Nat Rev Genet 2004; 5: 52–61, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ranki A, Nyberg M, Ovod V, Haltia M, Elovaara I, Raininko R, Haapasalo H, Krohn K. Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia. AIDS 1995; 9: 1001–1008, [PUBMED], [INFOTRIEVE]
- Rappaport J, Joseph J, Croul S, Alexander G, DelValle L, Amini S, Khalili K. Molecular pathway involved in HIV-1-induced CNS pathology: role of viral regulatory protein, Tat. J Leukoc Biol 1999; 65: 458–465, [PUBMED], [INFOTRIEVE], [CSA]
- Reddy R T, Achim C L, Sirko D A, Tehranchi S, Kraus F G, Wong-Staal F, Wiley C A. Sequence analysis of the V3 loop in brain and spleen of patients with HIV encephalitis. AIDS Res Hum Retroviruses 1996; 12: 477–482, [PUBMED], [INFOTRIEVE], [CSA]
- Rey-Cuille M, Berthier J, Bomsel-Demontoy M, Chaduc Y, Montagnier L, Hovanessian A G, Chakrabarti L A. Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease. J Virol 1998; 72: 3872–3886, [PUBMED], [INFOTRIEVE], [CSA]
- Richman D D. HIV chemotherapy. Nature 2001; 410: 995–1001, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Robertson S J, Hasenkrug K J, Chesebro B, Portis J L. Neurologic disease induced by polytropic murine retroviruses: Neurovirulence determined by efficiency of spread to microglial cells. J Virol 1997; 71: 5287–5294, [PUBMED], [INFOTRIEVE], [CSA]
- Ross H A, Rodrigo A G. Immune-mediated positive selection drives human immunodeficiency virus type 1 molecular variation and predicts disease duration. J Virol 2002; 76: 11715–11720, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ross H L, Gartner S, McArthur J C, Corboy J R, McAllister J J, Millhouse S, Wigdahl B. HIV-1 LTR C/EBP binding site sequence configurations preferentially encountered in brain lead to enhanced C/EBP factor binding and increased LTR-specific activity. J NeuroVirol 2001; 7: 235–249, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Ruiz L, Carcelain G, Martinez-Picado J, Frost S, Marfil S, Paredes R, Romeu J, Ferrer E, Morales-Lopetegi K, Autran B, Clotet B. HIV dynamics and T-cell immunity after three structured treatment interruptions in chronic HIV-1 infection. AIDS 2001; 15: F19–F27, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Ryzhova E V, Crino P, Shawver L, Westmoreland S V, Lackner A A, Gonzalez-Scarano F. Simian immunodeficiency virus encephalitis: analysis of envelope sequences from individual brain multinucleated giant cells and tissue samples. Virology 2002; 297: 57–67, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Sacktor N, McDermott M P, Marder K, Schifitto G, Selnes O A, McArthur J C, Stern Y, Albert S, Palumbo D, Kieburtz K, De Marcaida J A, Cohen B, Epstein L. HIV-associated cognitive impairment before and after the advent of combination therapy. J NeuroVirol 2002; 8: 136–142, [PUBMED], [INFOTRIEVE], [CSA]
- Saito Y, Sharer L R, Epstein L G, Michaels J, Mintz M, Louder M, Golding K, Cvetkovich T A, Blumberg B M. Overexpression of Nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissues. Neurology 1994; 44: 474–481, [PUBMED], [INFOTRIEVE], [CSA]
- Salomon H, Wainberg M A, Brenner B, Quan Y, Rouleau D, Cote P, LeBlanc R, Lefebvre E, Spira B, Tsoukas C, Sekaly R P, Conway B, Mayers D, Routy J P. Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use. Investigators of the Quebec Primary Infection Study. AIDS 2000; 14: F17–F23, [PUBMED], [INFOTRIEVE], [CROSSREF]
- Sanchez-Ramon S, MaBellon J, Resino S, Canto-Nogues C, Gurbindo D, Ramos J-T, Munoz-Fernandez M. Low blood CD8+ T-Lymphocytes and high circulating monocytes are predictors of HIV-1-Associated progressive encephalopathy in children. Pediatrics 2003; 111: 168–175, [CROSSREF]
- Sanders V J, Wiley C A, Hamilton R L. The mechanisms of neuronal damage in retroviral infections of the nervous system. Curr Top Microbiol Immunol 2001; 253: 179–201, [PUBMED], [INFOTRIEVE], [CSA]
- Sankale J L, DeLaTour R S, Marlink R G, Scheib R, Mboup S, Essex M E, Kanki P J. Distinct quasi-species in the blood and the brain of an HIV-2-infected individual. Virology 1996; 226: 418–423, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Sasseville V G, Lackner A A. Neuropathogenesis of simian immunodeficiency virus infection in macaque monkeys. J NeuroVirol 1997; 3: 1–9, [PUBMED], [INFOTRIEVE], [CSA]
- Sasseville V G, Smith M M, Mackay C R, Pauley D R, Mansfield K G, Ringler D J, Lackner A A. Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis. Am J Pathol 1996; 149: 1459–1467, [PUBMED], [INFOTRIEVE]
- Schrager L K, D'Souza M P. Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy. JAMA 1998; 280: 67–71, [PUBMED], [INFOTRIEVE], [CROSSREF], [CROSSREF]
- Schramm B, Penn M L, Speck R F, Chan S Y, DeClercq E, Schols D, Connor R I, Goldsmith M A. Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease. J Virol 2000; 74: 184–192, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Schwartz C, Catez P, Rohr O, Lecestre D, Aunis D, Schaeffer E. Functional interactions between C/EBP, Sp1, and COUP-TF regulate human immunodeficiency virus type 1 gene transcription in human brain cells. J Virol 2000; 74: 65–73, [PUBMED], [INFOTRIEVE], [CSA]
- Sei S, Boler A M, Nguyen G T, Stewart S K, Yang Q E, Edgerly M, Wood L V, Brouwers P, Venzon D J. Protective effect of CCR5 Δ 32 heterozygosity is restricted by SDF-1 genotype in children with HIV-1 infection. AIDS 2001; 15: 1343–1352, [PUBMED], [INFOTRIEVE], [CROSSREF], [CROSSREF]
- Shankarappa R, Margolick J B, Gange S J, Rodrigo A G, Upchurch D, Farzadegan H, Gupta P, Rinaldo C R, Learn G H, He X, Huang X L, Mullins J I. Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection. J Virol 1999; 73: 10489–104502, [PUBMED], [INFOTRIEVE], [CSA]
- Shapshak P, Segal D M, Crandall K A, Fujimura R K, Zhang B T, Xin K Q, Okuda K, Petito C K, Eisdorfer C, Goodkin K. Independent evolution of HIV type 1 in different brain regions. AIDS Res Hum Retroviruses 1999; 15: 811–820, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Sharkey M E, Teo I, Greenough T, Sharova N, Luzuriaga K, Sullivan J L, Bucy R P, Kostrikis L G, Haase A, Veryard C, Davaro R E, Cheeseman S H, Daly J S, Bova C, Ellison R T, 3rd, Mady B, Lai K K, Moyle G, Nelson M, Gazzard B, Shaunak S, Stevenson M. Persistence of episomal HIV-1 infection intermediates in patients on highly active antiretroviral therapy. Nat Med 2000; 6: 76–81, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Sheehy N, Desselberger U, Whitwell H, Ball J K. Concurrent evolution of regions of the envelope and polymerase genes of human immunodeficiency virus type 1 during zidovudine (AZT) therapy. J Gen Virol 1996; 77: 1071–1081, [PUBMED], [INFOTRIEVE], [CSA]
- Shi B, DeGirolami U, He J, Wang S, Lorenzo A, Busciglio J, Gabuzda D. Apoptosis induced by HIV-1 infection of the central nervous system. J Clin Invest 1996; 98: 1979–1990, [PUBMED], [INFOTRIEVE], [CSA]
- Shieh J T, Martin J, Baltuch G, Malim M H, Gonzalez-Scarano F. Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains. J Virol 2000; 74: 693–701, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Shrikant P, Benos D J, Tang L P, Benveniste E N. HIV glycoprotein 120 enhances intercellular adhesion molecule-1 gene expression in glial cells. Involvement of Janus kinase/signal transducer and activator of transcription and protein kinase C signaling pathways. J Immunol 1996; 156: 1307–1314, [PUBMED], [INFOTRIEVE]
- Silva C, Zhang K, Tsutsui S, Holden J K, Gill M J, Power C. Growth Hormone prevents human immunodeficiency virus-induced neurodegeneration: inhibition of neuronal p53. Ann Neurol 2003; 54: 605–614, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Smit T K, Wang B, Ng T, Osborne R, Brew B, Saksena N K. Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants. Virology 2001; 279: 509–526, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Smith K M, Crandall K A, Kneissl M L, Navia B A. PCR detection of host and HIV-1 sequences from archival brain tissue. J NeuroVirol 2000; 6: 164–171, [PUBMED], [INFOTRIEVE], [CSA]
- Song B, Cayabyab M, Phan N, Wang L, Axthelm M K, Letvin N L, Sodroski J G. Neutralization sensitivity of a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2N) isolated from an infected rhesus macaque with neurological disease. Virology 2004; 322: 168–181, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Soto C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nat Rev Neurosci 2003; 4: 49–60, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Speck R F, Wehrly K, Platt E J, Atchison R E, Charo I F, Kabat D, Chesebro B, Goldsmith M A. Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop. J Virol 1997; 71: 7136–7139, [PUBMED], [INFOTRIEVE], [CSA]
- Speth C, Schabetsberger T, Mohsenipour I, Stockl G, Wurzner R, Stoiber H, Lass-Florl C, Dierich M P. Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons. J Virol 2002; 76: 3179–3188, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Strelow L I, Janigro D, Nelson J A. The blood-brain barrier and AIDS. Adv Virus Res 2001; 56: 355–388, [PUBMED], [INFOTRIEVE], [CSA]
- Teo I, Veryard C, Barnes H, An S F, Jones M, Lantos P L, Luthert P, Shaunak S. Circular forms of unintegrated human immunodeficiency virus type 1 DNA and high levels of viral protein expression: association with dementia and multinucleated giant cells in the brains of patients with AIDS. J Virol 1997; 71: 2928–2933, [PUBMED], [INFOTRIEVE], [CSA]
- Tornatore C, Chandra R, Berger J R, Major E O. HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology 1994; 44: 481–487, [PUBMED], [INFOTRIEVE], [CSA]
- Tornatore C, Nath A, Amemiya K, Major E O. Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor α and interleukin-1β. J Virol 1991; 65: 6094–6100, [PUBMED], [INFOTRIEVE], [CSA]
- Torres-Munoz J, Stockton P, Tacoronte N, Roberts B, Maronpot R R, Petito C K. Detection of HIV-1 gene sequences in hippocampal neurons isolated from postmortem AIDS brains by laser capture microdissection. J Neuropathol Exp Neurol 2001; 60: 885–892, [PUBMED], [INFOTRIEVE], [CSA]
- Trillo-Pazos G, Bentsman G, Chao W, Sharer L, Morgello S, Volsky D J. HIV-1 infects human neuronal cultures. 4th International Conference on Neurovirology/10th Conference on Neuroscience of HIV Infection. 2002, J NeuroVirol 8 (Suppl 1): 23
- Trkola A, Ketas T, Kewalramani V N, Endorf F, Binley J M, Katinger H, Robinson J, Littman D R, Moore J P. Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage. J Virol 1998; 72: 1876–1885, [PUBMED], [INFOTRIEVE], [CSA]
- van Marle G, Ethier J, Silva C, MacVicar B A, Power C. Human immunodeficiency virus type 1 envelope-mediated neuropathogenesis: targeted gene delivery by a Sindbis virus expression vector. Virology 2003; 309: 61–74, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- van Marle G, Henry S, Todoruk T, Sullivan A, Silva C, Rourke S B, Holden J, McArthur J, Gill M J, Power C. Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10. Virology 2004; 329: 302–318, [PUBMED], [INFOTRIEVE]
- van Marle G, Rourke S B, Zhang K, Silva C, Ethier J, Gill M J, Power C. HIV dementia patients exhibit reduced viral neutralization and increased envelope sequence diversity in blood and brain. AIDS 2002; 16: 1905–1914, [PUBMED], [INFOTRIEVE], [CROSSREF], [CROSSREF]
- van Rij R P, Portegies P, Hallaby T, Lange J M, Visser J, Husman A M, van'tWout A B, Schuitemaker H. Reduced prevalence of the CCR5 Δ 32 heterozygous genotype in human immunodeficiency virus-infected individuals with AIDS dementia complex. J Infect Dis 1999; 180: 854–857, [PUBMED], [INFOTRIEVE], [CROSSREF], [CROSSREF]
- van'tWout A B, Ran L J, Kuiken C L, Kootstra N A, Pals S T, Schuitemaker H. Analysis of the temporal relationship between human immunodeficiency virus type 1 quasispecies in sequential blood samples and various organs obtained at autopsy. J Virol 1998; 72: 488–496, [CSA]
- Venturi G, Catucci M, Romano L, Corsi P, Leoncini F, Valensin P E, Zazzi M. Antiretroviral resistance mutations in human immunodeficiency virus type 1 reverse transcriptase and protease from paired cerebrospinal fluid and plasma samples. J Infect Dis 2000; 181: 740–745, [PUBMED], [INFOTRIEVE], [CROSSREF], [CROSSREF]
- Viscidi R P, Mayur K, Lederman H M, Frankel A D. Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1. Science 1989; 246: 1606–1608, [PUBMED], [INFOTRIEVE]
- vonHerrath M, Oldstone M B, Fox H S. Simian immunodeficiency virus (SIV)-specific CTL in cerebrospinal fluid and brains of SIV-infected rhesus macaques. J Immunol 1995; 154: 5582–5589
- Voulgaropoulou F, Tan B, Soares M, Hahn B, Ratner L. Distinct human immunodeficiency virus strains in the bone marrow are associated with the development of thrombocytopenia. J Virol 1999; 73: 3497–3504, [PUBMED], [INFOTRIEVE], [CSA]
- Walker B D, Goulder P J. AIDS. Escape from the immune system. Nature 2000; 407: 313–314, [PUBMED], [INFOTRIEVE], [CROSSREF], [CROSSREF]
- Wang T H, Donaldson Y K, Brettle R P, Bell J E, Simmonds P. Identification of shared populations of human immunodeficiency virus type 1 infecting microglia and tissue macrophages outside the central nervous system. J Virol 2001; 75: 11686–11699, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Wang W K, Dudek T, Essex M, Lee T H. Hypervariable region 3 residues of HIV type 1 gp120 involved in CCR5 coreceptor utilization: Therapeutic and prophylactic implications. Proc Natl Acad Sci U S A 1999; 96: 4558–4562, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Wesselingh S L, Thompson K A. Immunopathogenesis of HIV-associated dementia. Curr Opin Neurol 2001; 14: 375–379, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Westendorp M O, Shatrov V A, Schulze-Osthoff K, Frank R, Kraft M, Los M, Krammer P H, Droge W, Lehmann V. HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state. EMBO J 1995; 14: 546–554, [PUBMED], [INFOTRIEVE], [CSA]
- Wiley C A. Quantitative neuropathologic assessment of HIV-1 encephalitis. Curr Top Microbiol Immunol 1995; 202: 55–61, [PUBMED], [INFOTRIEVE], [CSA]
- Wiley C A, Soontornniyomkij V, Radhakrishnan L, Masliah E, Mellors J, Hermann S A, Dailey P, Achim C L. Distribution of brain HIV load in AIDS. Brain Pathol 1998; 8: 277–284, [PUBMED], [INFOTRIEVE]
- Wodarz D, Nowak M A. Dynamics of HIV pathogenesis and treatment. Origin and evolution of viruses, E Domingo, J J Holland. Academic Press, New York 1999; pp 197–223
- Wong J K, Ignacio C C, Torriani F, Havlir D, Fitch N J, Richman D D. In vivo compartmentalization of human immunodeficiency virus: evidence from the examination of pol sequences from autopsy tissues. J Virol 1997; 71: 2059–2071, [PUBMED], [INFOTRIEVE], [CSA]
- Xiao H, Neuveut C, Tiffany H L, Benkirane M, Rich E A, Murphy P M, Jeang K T. Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1. Proc Natl Acad Sci U S A 2000; 97: 11466–11471, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Yi Y, Chen W, Frank I, Cutilli J, Singh A, Starr-Spires L, Sulcove J, Kolson D L, Collman R G. An unusual syncytia-inducing human immunodeficiency virus type 1 primary isolate from the central nervous system that is restricted to CXCR4, replicates efficiently in macrophages, and induces neuronal apoptosis. J NeuroVirol 2003; 9: 432–441, [PUBMED], [INFOTRIEVE], [CSA]
- Yong V W, Krekoski C A, Forsyth P A, Bell R, Edwards D R. Matrix metalloproteinases and diseases of the CNS. Trends Neurosci 1998; 21: 75–80, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Zagury D, Lachgar A, Chams V, Fall L S, Bernard J, Zagury J F, Bizzini B, Gringeri A, Santagostino E, Rappaport J, Feldman M, Burny A, Gallo R C. Interferon α and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS. Proc Natl Acad Sci U S A 1998; 95: 3851–3856, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Zhang K, Hawken M, Rana F, Welte F J, Gartner S, Goldsmith M A, Power C. Human immunodeficiency virus type 1 clade A and D neurotropism: molecular evolution, recombination, and coreceptor use. Virology 2001; 283: 19–30, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Zhang K, McQuibban G A, Silva C, Butler G S, Johnston J B, Holden J, Clark-Lewis I, Overall C M, Power C. HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration. Nat Neurosci 2003a; 6: 1064–1071, [PUBMED], [INFOTRIEVE], [CROSSREF], [CROSSREF]
- Zhang K, Rana F, Silva C, Ethier J, Wehrly K, Chesebro B, Power C. Human immunodeficiency virus type 1 envelope-mediated neuronal death: uncoupling of viral replication and neurotoxicity. J Virol 2003b; 77: 6899–6912, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF], [CROSSREF]
- Zheng J, Thylin M R, Ghorpade A, Xiong H, Persidsky Y, Cotter R, Niemann D, Che M, Zeng Y C, Gelbard H A, Shepard R B, Swartz J M, Gendelman H E. Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia. J Neuroimmunol 1999; 98: 185–200, [PUBMED], [INFOTRIEVE], [CROSSREF], [CROSSREF]
- Zink M C, Suryanarayana K, Mankowski J L, Shen A, Piatak M, Jr, Spelman J P, Carter D L, Adams R J, Lifson J D, Clements J E. High viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis. J Virol 1999; 73: 10480–10488, [PUBMED], [INFOTRIEVE], [CSA]