Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization

References

• Aiuti A, Turchetto L, Cota M, Cipponi A, Brambilla A, Arcelloni C, Paroni R, Vicenzi E, Bordignon C, Poli G. Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus. Blood 1999; 94: 62–73, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Bachis A, Major E O, Mocchetti I. Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization. J Neurosci 2003; 23: 5715–5722, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Bachis A, Mocchetti I. The chemokine receptor CXCR4 and not the N-methyl-D-aspartate receptor mediates gp120 neurotoxicity in cerebellar granule cells. J Neurosci Res 2004; 75: 75–82, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Badr G, Borhis G, Treton D, Moog C, Garraud O, Richard Y. HIV type 1 glycoprotein 120 inhibits human B cell chemotaxis to CXC chemokine ligand (CXCL) 12, CC chemokine ligand (CCL)20, and CCL21. J Immunol 2005; 175: 302–310, [INFOTRIEVE], [CSA]
   Google Scholar
• Baribaud F, Edwards T G, Sharron M, Brelot A, Heveker N, Price K, Mortari F, Alizon M, Tsang M, Doms R W. Antigenically distinct conformations of CXCR4. J Virol 2001; 75: 8957–8967, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Bodner A, Toth P T, Oh S B, Lu M, Tran P B, Chin R K, Ren D, Miller R J. CD4 dependence of gp120IIIB-CXCR4 interaction is cell-type specific. J Neuroimmunol 2003; 140: 1–12, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Catani M V, Corasaniti M T, Navarra M, Nistico G, Finazzi-Agro A, Melino G. gp120 induces cell death in human neuroblastoma cells through the CXCR4 and CCR5 chemokine receptors. J Neurochem 2000; 74: 2373–2379, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Chalasani S H, Baribaud F, Coughlan C M, Sunshine M J, Lee V M, Doms R W, Littman D R, Raper J A. The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells. J Neurosci 2003; 23: 4601–4612, [INFOTRIEVE], [CSA]
   Google Scholar
• Cook D G, Fantini J, Spitalnik S L, Gonzalez-Scarano F. Binding of human immunodeficiency virus type I (HIV-1) gp120 to galactosylceramide (GalCer): relationship to the V3 loop. Virology 1994; 201: 206–214, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Ferguson S S. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 2001; 53: 1–24, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Fernandis A Z, Cherla R P, Chernock R D, Ganju R K. CXCR4/CCR5 down-modulation and chemotaxis are regulated by the proteasome pathway. J Biol Chem 2002; 277: 18111–18117, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Fernandis A Z, Cherla R P, Ganju R K. Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45. J Biol Chem 2003; 278: 9536–9543, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Garden G A, Budd S L, Tsai E, Hanson L, Kaul M, D'Emilia D M, Friedlander R M, Yuan J, Masliah E, Lipton S A. Caspase cascades in human immunodeficiency virus-associated neurodegeneration. J Neurosci 2002; 22: 4015–4024, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Goel R, Baldassare J J. beta-Arrestin 1 couples thrombin to the rapid activation of the Akt pathway. Ann N Y Acad Sci 2002; 973: 138–141, [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Goel R, Phillips-Mason P J, Raben D M, Baldassare J J. alpha-Thrombin induces rapid and sustained Akt phosphorylation by beta-arrestin1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression. J Biol Chem 2002; 277: 18640–18648, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Hesselgesser J, Halks-Miller M, DelVecchio V, Peiper S C, Hoxie J, Kolson D L, Taub D, Horuk R. CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons. Curr Biol 1997; 7: 112–121, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Hesselgesser J, Taub D, Baskar P, Greenberg M, Hoxie J, Kolson D L, Horuk R. Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4. Curr Biol 1998; 8: 595–598, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kaul M, Garden G A, Lipton S A. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 2001; 410: 988–994, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Kaul M, Lipton S A. Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proc Natl Acad Sci U S A 1999; 96: 8212–8216, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Khan M Z, Brandimarti R, Musser B J, Resue D M, Fatatis A, Meucci O. The chemokine receptor CXCR4 regulates cell-cycle proteins in neurons. J NeuroVirol 2003; 9: 300–314, [INFOTRIEVE], [CSA]
   Google Scholar
• Khan M Z, Brandimarti R, Patel J P, Huynh N, Wang J, Huang Z, Fatatis A, Meucci O. Apoptotic and antiapoptotic effects of CXCR4: is it a matter of intrinsic efficacy? Implications for HIV neuropathogenesis. AIDS Res Hum Retroviruses 2004; 20: 1063–1071, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Khan M Z, Shimizu S, Patel J P, Nelson A, Le M T, Mullen-Przeworski A, Brandimarti R, Fatatis A, Meucci O. Regulation of neuronal P53 activity by CXCR4. Mol Cell Neurosci 2005; 30: 58–66, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Lazarini F, Casanova P, Tham T N, De Clercq E, Arenzana-Seisdedos F, Baleux F, Dubois-Dalcq M. Differential signalling of the chemokine receptor CXCR4 by stromal cell-derived factor 1 and the HIV glycoprotein in rat neurons and astrocytes. Eur J Neurosci 2000; 12: 117–125, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lazarini F, Tham T N, Casanova P, Arenzana-Seisdedos F, Dubois-Dalcq M. Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system. Glia 2003; 42: 139–148, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lefkowitz R J, Shenoy S K. Transduction of receptor signals by beta-arrestins. Science 2005; 308: 512–517, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Long D, Berson J F, Cook D G, Doms R W. Characterization of human immunodeficiency virus type 1 gp120 binding to liposomes containing galactosylceramide. J Virol 1994; 68: 5890–5898, [INFOTRIEVE], [CSA]
   Google Scholar
• Mattson M P, Haughey N J, Nath A. Cell death in HIV dementia. Cell Death Differ 2005; 12(Suppl 1)893–904, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Meucci O, Fatatis A, Simen A A, Bushell T J, Gray P W, Miller R J. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc Natl Acad Sci U S A 1998; 95: 14500–14505, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Meucci O, Miller R J. gp120-induced neurotoxicity in hippocampal pyramidal neuron cultures: protective action of TGF-beta1. J Neurosci 1996; 16: 4080–4088, [INFOTRIEVE], [CSA]
   Web of Science ®Google Scholar
• Neel N F, Schutyser E, Sai J, Fan G H, Richmond A. Chemokine receptor internalization and intracellular trafficking. Cytokine Growth Factor Rev 2005; 16: 637–658, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Pandey V, Bolsover S R. Immediate and neurotoxic effects of HIV protein gp120 act through CXCR4 receptor. Biochem Biophys Res Commun 2000; 274: 212–215, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Povsic T J, Kohout T A, Lefkowitz R J. Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis. J Biol Chem 2003; 278: 51334–51339, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Revankar C M, Vines C M, Cimino D F, Prossnitz E R. Arrestins block G protein-coupled receptor-mediated apoptosis. J Biol Chem 2004; 279: 24578–24584, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Signoret N, Pelchen-Matthews A, Mack M, Proudfoot A E, Marsh M. Endocytosis and recycling of the HIV coreceptor CCR5. J Cell Biol 2000; 151: 1281–1294, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Tarasova N I, Stauber R H, Michejda C J. Spontaneous and ligand-induced trafficking of CXC-chemokine receptor 4. J Biol Chem 1998; 273: 15883–15886, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tran P B, Miller R J. Chemokine receptors: signposts to brain development and disease. Nat Rev Neurosci 2003; 4: 444–455, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wang J M, Ueda H, Howard O M, Grimm M C, Chertov O, Gong X, Gong W, Resau J H, Broder C C, Evans G, Arthur L O, Ruscetti F W, Oppenheim J J. HIV-1 envelope gp120 inhibits the monocyte response to chemokines through CD4 signal-dependent chemokine receptor down-regulation. J Immunol 1998; 161: 4309–4317, [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Zhang K, McQuibban G A, Silva C, Butler G S, Johnston J B, Holden J, Clark-Lewis I, Overall C M, Power C. HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration. Nat Neurosci 2003a; 6: 1064–1071, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Zhang K, Rana F, Silva C, Ethier J, Wehrly K, Chesebro B, Power C. Human immunodeficiency virus type 1 envelope-mediated neuronal death: uncoupling of viral replication and neurotoxicity. J Virol 2003b; 77: 6899–6912, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Zheng J, Thylin M R, Ghorpade A, Xiong H, Persidsky Y, Cotter R, Niemann D, Che M, Zeng Y C, Gelbard H A, Shepard R B, Swartz J M, Gendelman H E. Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia. J Neuroimmunol 1999; 98: 185–200, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Zhou N, Luo Z, Luo J, Fan X, Cayabyab M, Hiraoka M, Liu D, Han X, Pesavento J, Dong C Z, Wang Y, An J, Kaji H, Sodroski J G, Huang Z. Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines. J Biol Chem 2002; 277: 17476–17485, [INFOTRIEVE], [CSA], [CROSSREF]
   Google Scholar
• Zou Y R, Kottmann A H, Kuroda M, Taniuchi I, Littman D R. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 1998; 393: 595–599, [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar