Engineering the Japanese encephalitis virus RNA genome for the expression of foreign genes of various sizes: Implications for packaging capacity and RNA replication efficiency

References

• Agapov E V, Frolov I, Linderbach B D, Pragai B M, Schlesinger S, Rice C M. Noncytopathic Sindbis virus RNA replicons for heterologous gene expression. Proc Natl Acad Sci U S A 1998; 95: 12989–12994
   PubMed Web of Science ®Google Scholar
• Alvarez D E, Lodeiro M F, Luduena S J, Pietrasanta L I, Gamarnik A V. Long-range RNA-RNA interactions circularize the dengue virus genome. J Virol 2005; 79: 6631–6643
   PubMed Web of Science ®Google Scholar
• Bonaldo M C, Garratt R C, Caufour P S, Freire M S, Rodrigues M M, Nussenzweig R S, Galler R. Surface expression of an immunodominant malaria protein B cell epitope by yellow fever virus. J Mol Biol 2002; 315: 873–885
   PubMed Web of Science ®Google Scholar
• Bonaldo M C, Garratt R C, Marchevsky R S, Coutinho E S, Jabor A V, Almeida L F, Yamamura A M, Duarte A S, Oliveira P J, Lizeu J O, Camacho L A, Freire M S, Galler R. Attenuation of recombinant yellow fever 17D viruses expressing foreign protein epitopes at the surface. J Virol 2005; 79: 8602–8613
   PubMed Web of Science ®Google Scholar
• Bredenbeek P J, Kooi E A, Lindenbach B, Huijkman N, Rice C M, Spaan W J. A stable full-length yellow fever virus cDNA clone and the role of conserved RNA elements in flavivirus replication. J Gen Virol 2003; 84: 1261–1268
   PubMed Web of Science ®Google Scholar
• Bredenbeek P J, Molenkamp R, Spaan W J, Deubel V, Marianneau P, Salvato M S, Moshkoff D, Zapata J, Tikhonov I, Patterson J, Carrion R, Ticer A, Brasky K, Lukashevich I S. A recombinant yellow fever 17D vaccine expressing Lassa virus glycoproteins. Virology 2006; 345: 299–304
   PubMed Web of Science ®Google Scholar
• Corver J, Lenches E, Smith K, Robison R A, Sando T, Strauss E G, Strauss J H. Fine mapping of a cis-acting sequence element in yellow fever virus RNA that is required for RNA replication and cyclization. J Virol 2003; 77: 2265–2270
   PubMed Web of Science ®Google Scholar
• Fayzulin R, Scholle F, Petrakova O, Frolov I, Mason P W. Evaluation of replicative capacity and genetic stability of West Nile virus replicons using highly efficient packaging cell lines. Virology 2006; 351: 196–209
   Google Scholar
• Flotte T R, Afione S A, Solow R, Drumm M L, Markakis D, Guggino W B, Zeitlin P L, Carter B J. Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter. J Biol Chem 1993; 268: 3781–3790
   PubMed Web of Science ®Google Scholar
• Gehrke R, Ecker M, Aberle S W, Allison S L, Heinz F X, Mandl C W. Incorporation of tick-borne encephalitis virus replicons into virus-like particles by a packaging cell line. J Virol 2003; 77: 8924–8933
   PubMed Web of Science ®Google Scholar
• Gehrke R, Heinz F X, Davis N L, Mandl C W. Heterologous gene expression by infectious and replicon vectors derived from tick-borne encephalitis virus and direct comparison of this flavivirus system with an alphavirus replicon. J Gen Virol 2005; 86: 1045–1053
   Google Scholar
• Hahn C S, Hahn Y S, Rice C M, Lee E, Dalgarno L, Strauss E G, Strauss J H. Conserved elements in the 3′ untranslated region of flavivirus RNAs and potential cyclization sequences. J Mol Biol 1987; 198: 33–41
   PubMed Web of Science ®Google Scholar
• Harvey T J, Liu W J, Wang X J, Linedale R, Jacobs M, Davidson A, Le T T, Anraku I, Suhrbier A, Shi P Y, Khromykh A A. Tetracycline-inducible packaging cell line for production of flavivirus replicon particles. J Virol 2004; 78: 531–538
   PubMed Web of Science ®Google Scholar
• Hennessy S, Liu Z, Tsai T F, Strom B L, Wan C M, Liu H L, Wu T X, Yu H J, Liu Q M, Karabatsos N, Bilker W B, Halstead S B. Effectiveness of live-attenuated Japanese encephalitis vaccine (SA14-14-2): a case control study. Lancet 1996; 347: 1583–1586
   PubMed Web of Science ®Google Scholar
• Jones C T, Patkar C G, Kuhn R J. Construction and applications of yellow fever virus replicons. Virology 2005; 331: 247–259
   PubMed Web of Science ®Google Scholar
• Kaufman R J. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 1999; 13: 1211–1233
   PubMed Web of Science ®Google Scholar
• Khromykh A A, Meka H, Guyatt K J, Westaway E G. Essential role of cyclization sequences in flavivirus RNA replication. J Virol 2001; 75: 6719–6728
   PubMed Web of Science ®Google Scholar
• Khromykh A A, Varnavski A N, Westaway E G. Encapsidation of the flavivirus Kunjin replicon RNA by using a complementation system providing Kunjin virus structural proteins in trans. J Virol 1998; 72: 5967–5977
   PubMed Web of Science ®Google Scholar
• Khromykh A A, Westaway E G. Subgenomic replicons of the flavivirus Kunjin: construction and applications. J Virol 1997; 71: 1497–1505
   PubMed Web of Science ®Google Scholar
• Lai C J, Monath T P. Chimeric flaviviruses: novel vaccines against dengue fever, tick-borne encephalitis, and Japanese encephalitis. Adv Virus Res 2003; 61: 469–509
   PubMedGoogle Scholar
• Lindenbach B D, Rice C M. Flaviviridae: The viruses and their replication. Fields virology, 4th ed., D M Knipe, P M Howley, D E Griffin, R A Lamb, M A Martin, B Roizman, S E Straus. Lippincott Williams & Wilkins Publishers, Philadelphia 2001; 991–1041
   Google Scholar
• Lo M K, Tilgner M, Bernard K A, Shi P Y. Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3′ untranslated region of West Nile virus by use of a reporting replicon that differentiates between viral translation and RNA replication. J Virol 2003; 77: 10004–10014
   PubMed Web of Science ®Google Scholar
• Markoff L. 5′- and 3′-noncoding regions in flavivirus RNA. Adv Virus Res 2003; 59: 177–228
   PubMed Web of Science ®Google Scholar
• Mason P W, Shustov A V, Frolov I. Production and characterization of vaccines based on flaviviruses defective in replication. Virology 2006; 351: 432–443
   PubMed Web of Science ®Google Scholar
• Molenkamp R, Kooi E A, Lucassen M A, Greve S, Thijssen J C, Spaan W J, Bredenbeek P J. Yellow fever virus replicons as an expression system for hepatitis C virus structural proteins. J Virol 2003; 77: 1644–1648
   PubMed Web of Science ®Google Scholar
• Monath T P. Yellow fever vaccine, 4th ed. WB Saunders, Philadelphia 2003
   Google Scholar
• Pahl H L. Signal transduction from the endoplasmic reticulum to the cell nucleus. Physiol Rev 1999; 79: 683–701
   PubMed Web of Science ®Google Scholar
• Pang X, Zhang M, Dayton A I. Development of dengue virus replicons expressing HIV-1 gp120 and other heterologous genes: a potential future tool for dual vaccination against dengue virus and HIV. BMC Microbiol 2001; 1: 28–36
   Google Scholar
• Pierson T C, Diamond M S, Ahmed A A, Valentine L E, Davis C W, Samuel M A, Hanna S L, Puffer B A, Doms R W. An infectious West Nile virus that expresses a GFP reporter gene. Virology 2005; 334: 28–40
   PubMed Web of Science ®Google Scholar
• Scholle F, Girard Y A, Zhao Q, Higgs S, Mason P W. trans-Packaged West Nile virus-like particles: infectious properties in vitro and in infected mosquito vectors. J Virol 2004; 78: 11605–11614
   PubMed Web of Science ®Google Scholar
• Shi P Y, Tilgner M, Lo M K. Construction and characterization of subgenomic replicons of New York strain of West Nile virus. Virology 2002; 296: 219–233
   PubMed Web of Science ®Google Scholar
• Solomon T. Recent advances in Japanese encephalitis. J NeuroVirol 2003; 9: 274–283
   PubMed Web of Science ®Google Scholar
• Su H L, Liao C L, Lin Y L. Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response. J Virol 2002; 76: 4162–4171
   PubMed Web of Science ®Google Scholar
• Varnavski A N, Khromykh A A. Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterologous genes. Virology 1999; 255: 366–375
   PubMed Web of Science ®Google Scholar
• Wang J J, Liao C L, Chiou Y W, Chiou C T, Huang Y L, Chen L K. Ultrastructure and localization of E proteins in cultured neuron cells infected with Japanese encephalitis virus. Virology 1997; 238: 30–39
   Google Scholar
• Winer J, Jung C K, Shackel I, Williams P M. Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 1999; 270: 41–49
   PubMed Web of Science ®Google Scholar
• Xin Y Y, Ming Z G, Peng G Y, Jian A, Min L H. Safety of a live-attenuated Japanese encephalitis virus vaccine (SA14-14-2) for children. Am J Trop Med Hyg 1988; 39: 214–217
   PubMed Web of Science ®Google Scholar
• You S, Falgout B, Markoff L, Padmanabhan R. In vitro RNA synthesis from exogenous dengue viral RNA templates requires long range interactions between 5′- and 3′-terminal regions that influence RNA structure. J Biol Chem 2001; 276: 15581–15591
   PubMedGoogle Scholar
• Yun S I, Kim S Y, Rice C M, Lee Y M. Development and application of a reverse genetics system for Japanese encephalitis virus. J Virol 2003; 77: 6450–6465
   PubMed Web of Science ®Google Scholar