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Short Communication

Serotonin receptor 2A blocker (risperidone) has no effect on human polyomavirus JC infection of primary human fetal glial cells

, , , , & , PhD
Pages 448-454 | Received 29 Nov 2007, Published online: 10 Jul 2009

References

  • Agostini HT, Deckhut A, Jobes DV, Girones R, Schlunck G, Prost MG, Frias C, Perez-Trallero E, Ryschkewitsch CF, Stoner GL. Genotypes of JC virus in East, Central and Southwest Europe. J Gen Virol 2001; 82: 1221–331
  • Agostini HT, Ryschkewitsch CF, Singer EJ, Stoner GL. JC virus regulatory region rearrangements and genotypes in progressive multifocal leukoencephalopathy: two independent aspects of virus variation. J Gen Virol 1997; 78(Pt 3)659–664
  • Agostini HT, Ryschkewitsch CF, Stoner GL. Genotype profile of human polyomavirus JC excreted in urine of immunocompetent individuals. J Clin Microbiol 1996; 34: 159–164
  • Aksamit AJ. Treatment of non-AIDS progressive multifocal leukoencephalopathy with cytosine arabinoside. J NeuroVirol 2001; 7: 386–390
  • Altschuler EL, Kast RE. The atypical antipsychotic agents ziprasidone [correction of zisprasidone], risperdone and olanzapine as treatment for and prophylaxis against progressive multifocal leukoencephalopathy. Med Hypotheses 2005; 65: 585–586
  • Antinori A, Ammassari A, Giancola ML, Cingolani A, Grisetti S, Murri R, Alba L, Ciancio B, Soldani F, Larussa D, Ippolito G, De Luca A. Epidemiology and prognosis of AIDS-associated progressive multifocal leukoencephalopathy in the HAART era. J NeuroVirol 2001; 7: 323–328
  • Antinori A, Cingolani A, Lorenzini P, Giancola ML, Uccella I, Bossolasco S, Grisetti S, Moretti F, Vigo B, Bongiovanni M, Del Grosso B, Arcidiacono MI, Fibbia GC, Mena M, Finazzi MG, Guaraldi G, Ammassari A, d'Arminio Monforte A, Cinque P, De Luca A. Clinical epidemiology and survival of progressive multifocal leukoencephalopathy in the era of highly active antiretroviral therapy: data from the Italian Registry Investigative Neuro AIDS (IRINA). J NeuroVirol 2003; 9(Suppl 1)47–53
  • Chapagain ML, Nguyen T, Bui T, Verma S, Nerurkar VR 2006. Comparison of real-time PCR and hemagglutination assay for quantitation of human polyomavirus JC. Virol J 3: 3. Please see http://www.virologyj.com/content/3/1/3.
  • Chapagain ML, Verma S, Mercier F, Yanagihara R, Nerurkar VR. Polyomavirus JC infects human brain microvascular endothelial cells independent of serotonin receptor 2A. Virology 2007; 364: 55–63
  • Co JK, Verma S, Gurjav U, Sumibcay L, Nerurkar VR. Interferon- alpha and-beta restrict polyomavirus JC replication in primary human fetal glial cells: implications for progressive multifocal leukoencephalopathy therapy. J Infect Dis 2007; 196: 712–718
  • Colosimo C, Lebon P, Martelli M, Tumminelli F, Mandelli F. Alpha-interferon therapy in a case of probable progressive multifocal leukoencephalopathy. Acta Neurol Belg 1992; 92: 24–29
  • De Luca A, Giancola ML, Ammassari A, Grisetti S, Cingolani A, Larussa D, Alba L, Murri R, Ippolito G, Cauda R, Monforte A, Antinori A. Potent anti-retroviral therapy with or without cidofovir for AIDS-associated progressive multifocal leukoencephalopathy: extended follow-up of an observational study. J NeuroVirol 2001; 7: 364–368
  • De Luca A, Giancola ML, Cingolani A, Ammassari A, Gillini L, Murri R, Antinori A. Clinical and virological monitoring during treatment with intrathecal cytarabine in patients with AIDS-associated progressive multifocal leukoencephalopathy. Clin Infect Dis 1999; 28: 624–628
  • Decker M, Schleifer KJ, Nieger M, Lehmann J. Dopamine/serotonin receptor ligands. Part VIII: The dopamine receptor antagonist LE300—modelled and X-ray structure plus further pharmacological characterization, including serotonin receptor binding, biogenic amine transporter testing and in vivo testings. Eur J Med Chem 2004; 39: 481–489
  • Dubois V, Moret H, Lafon ME, Brodard V, Icart J, Ruffault A, Guist'hau O, Buffet-Janvresse C, Abbed K, Dussaix E, Ingrand D. JC virus genotypes in France: molecular epidemiology and potential significance for progressive multifocal leukoencephalopathy. J Infect Dis 2001; 183: 213–217
  • Elphick GF, Querbes W, Jordan JA, Gee GV, Eash S, Manley K, Dugan A, Stanifer M, Bhatnagar A, Kroeze WK, Roth BL, Atwood WJ. The human polyomavirus, JCV, uses serotonin receptors to infect cells. Science 2004; 306: 1380–1383
  • Enting RH, Portegies P. Cytarabine and highly active antiretroviral therapy in HIV-related progressive multifocal leukoencephalopathy. J Neurol 2000; 247: 134–138
  • Focosi D, Fazzi R, Montanaro D, Emdin M, Petrini M. Progressive multifocal leukoencephalopathy in a haploidentical stem cell transplant recipient: a clinical, neuroradiological and virological response after treatment with risperidone. Antiviral Res 2007; 74: 156–158
  • Focosi D, Kast RE, Maggi F, Ceccherini-Nelli L, Petrini M. Risperidone-induced reduction in JC viruria as a surrogate marker for efficacy against progressive multifocal leukoencephalopathy and hemorrhagic cystitis. J Clin Virol 2007b; 39: 63–64
  • Geschwind MD, Skolasky RI, Royal WS, McArthur JC. The relative contributions of HAART and alpha-interferon for therapy of progressive multifocal leukoencephalopathy in AIDS. J NeuroVirol 2001; 7: 353–357
  • Huang SS, Skolasky RL, Dal Pan GJ, Royal W., 3rd, McArthur JC. Survival prolongation in HIV-associated progressive multifocal leukoencephalopathy treated with alpha-interferon: an observational study. J NeuroVirol 1998; 4: 324–332
  • Lima MA, Katz-Brull R, Lenkinski RE, Nunez R, Feinrider D, Koralnik IJ. Remission of progressive multifocal leukoencephalopathy and primary central nervous system lymphoma in an HIV-infected patient. Eur J Neurol 2007; 14: 598–602
  • Marra CM, Rajicic N, Barker DE, Cohen BA, Clifford D, Donovan Post MJ, Ruiz A, Bowen BC, Huang ML, Queen-Baker J, Andersen J, Kelly S, Shriver S. A pilot study of cidofovir for progressive multifocal leukoencephalopathy in AIDS. AIDS 2002; 16: 1791–1797
  • Maxishima M, Shiga T, Shutoh F, Hamada S, Maeshima T, Okado N. Serotonin 2A receptor-like immunoreactivity is detected in astrocytes but not in oligodendrocytes of rat spinal cord. Brain Res 2001; 889: 270–273
  • Morisset S, Sahm UG, Traiffort E, Tardivel-Lacombe J, Arrang JM, Schwartz JC. Atypical neuroleptics enhance histamine turnover in brain via 5-Hydroxytryptamine2A receptor blockade. J Pharmacol Exp Ther 1999; 288: 590–596
  • Nath A, Venkataramana A, Reich DS, Cortese I, Major EO. Progression of progressive multifocal leukoencephalopathy despite treatment with beta-interferon. Neurology 2006; 66: 149–150
  • O'Hara BA, Atwood WJ. Interferon beta1-a and selective anti-5HT(2a) receptor antagonists inhibit infection of human glial cells by JC virus. Virus Res 2008; 132: 97–103
  • Owczarczyk K, Hilker R, Brunn A, Hallek M, Rubbert A. Progressive multifocal leucoencephalopathy in a patient with sarcoidosis—successful treatment with cidofovir and mirtazapine. Rheumatology (Oxford) 2007; 46: 888–890
  • Padgett BL, Rogers CM, Walker DL. JC virus, a human polyomavirus associated with progressive multifocal leukoencephalopathy: additional biological characteristics and antigenic relationships. Infect Immun 1977; 15: 656–662
  • Padgett BL, Walker DL, ZuRhein GM, Eckroade RJ, Dessel BH. Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1971; 1: 1257–1260
  • Santagata S, Kinney HC. Mechanism of JCV entry into oligodendrocytes. Science 2005; 309: 381–382
  • Shah KV, Daniel RW, Strickler HD, Goedert JJ. Investigation of human urine for genomic sequences of the primate polyomaviruses simian virus 40, BK virus, and JC virus. J Infect Dis 1997; 176: 1618–1621
  • Verma S, Cikurel K, Koralnik IJ, Morgello S, Cunningham-Rundles C, Weinstein ZR, Bergmann C, Simpson DM. Mirtazapine in progressive multifocal leukoencephalopathy associated with polycythemia vera. J Infect Dis 2007; 196: 709–711
  • Vulliemoz S, Lurati-Ruiz F, Borruat FX, Delavelle J, Koralnik IJ, Kuntzer T, Bogousslavsky J, Picard F, Landis T, Du Pasquier RA. Favourable outcome of progressive multifocal leucoencephalopathy in two patients with dermatomyositis. J Neurol Neurosurg Psychiatry 2006; 77: 1079–1082
  • Wyen C, Hoffmann C, Schmeisser N, Wohrmann A, Qurishi N, Rockstroh J, Esser S, Rieke A, Ross B, Lorenzen T, Schmitz K, Stenzel W, Salzberger B, Fatkenheuer G. Progressive multifocal leukencephalopathy in patients on highly active antiretroviral therapy: survival and risk factors of death. J Acquir Immune Defic Syndr 2004; 37: 1263–1268

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