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Research Article

Bovine Spongiform Encephalopathy: Comparison between the 'Prion' Hypothesis and the Autoimmune Theory

Pages 265-273 | Published online: 13 Jul 2009

  • Kimberlin RH. Bovine spongiform encephalopathy: an appraisal of the current epidemic in the United Kingdom. Intervirology 1993; 35:208-18.
  • Anderson RM, Donnelly CA, Ferguson NM, et al. Transmission dynamics and epidemiology of BSE in British cattle. Nature 1996; 382:779-88.
  • Crawford MA, Budowski P, Drury P, et al. The nutritional contribution to bovine spongiform encephalopathy. Nutrition & Health 1991, 7: 61-8.
  • Purdey M. Are organophosphate pesticides involved in the causation of bovine spongiform encephalopathy? Hypothesis based upon a literature review and limited trials on BSE cattle. J Nutr Meal 1994; 4:43-82.
  • Jeffrey M, Scott JR, Williams A, et al. Ultrastructural features of spongiform encephalopathy transmitted to mice from three species of bovidae. Acta Neuropathologica 1992; 84:559-69.
  • Prusiner S, Fuzi M, Scott M, et al. Immunologic and molecular biologic studies of prion proteins in bovine spongiform encephalopathy. J Infect Dis 1993; 167:602-13.
  • Prusiner S. Biology and genetics of prion diseases. Ann Rev Microbiol 1994; 48:655-86.
  • Weissmann C. Molecular biology of transmissible spongiform encephalopathies. FEBS Letters 1996; 389:3-11.
  • Lasmezas C, Deslys J., Robain O, et al. Transmission of the BSE agent to mice in the absence of detectable prion protein. Science 1997. 275: 402-5.
  • Prusiner S. Scrapie prions. Ann Rev Microbiol 1989; 43:345-74.
  • Taylor D, McConnell I, Fraser It, et al. Scrapie infection can be established readily through skin scarification in immunocompetent but not in immunodeficient mice. J Gen Virol 1996, 77: 1595-9.
  • Ebringer A. The link between genes and disease. New Scientist 1978, 79: 865-7.
  • Cunningham M, Antone S, Guliza J, et al. Cytotoxic and viral neutralising antibodies crossreact with streptococcal M protein, enteroviruses and human cardiacmyosin. Proc Nat Acad Sci 1991; 89:1320-4.
  • Fielder M, Wilson C, Ebringer A, et al. The specificity of the anti-Proteus antibody in response tissue-typed rheumatoid arthritis (RA) patients from Brest. Rheumatol Int 1995; 15:79-82.
  • Ebringer A. Ankylosing spondylitis is caused by Klebsiella. Rheum Dis Clin NAmer 1992; 18:105-21.
  • Stastny P. Association of the B-cell alloantigen Drw4 with rheumatoid arthritis. N Engl J Med 1978; 289:869-71.
  • Gregersen P, Silver J, Winchester R. The shared epitope hypothesis: An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 1987; 30:1205-13.
  • Wilson C, Ebringer A, Ahmadi K, et al. Shared amino acid sequences between major histocompatibility complex class II glycoproteins, type XI collagen and Proteus mirabilis in rheumatoid arthritis. Ann Rheum Dis 1995; 54:216-20.
  • Subair It, Ebringer A, Wilson S, et al. Elevation in anti-Proteus antibodies in patients with rheumatoid arthritis from Bermuda and England. J Rheumatol 1995; 22:825-8.
  • Bywaters E. Historical perspectives in the aetiology of ankylosing spondylitis. Br J Rheumatol 1983; 22:1-4.
  • Khan M. Genetics of HLA-B27. Br J Rheumatol 1988; 27:6-11.
  • Schwimmbeck P, Yu D, Oldstone M. Autoantibodies to HLA-B27 in patients with ankylosing spondylitis and Reiter's syndrome. Molecular mimicry with Klebsiella pneumoniae as potential mechanism of autoimmune disease. J Exp Med 1987; 166:173-81.
  • Husby G, Tsuchiya N, Schwimmbeck P, et al. Crossreactive epitope with Klebsiella pneumoniae nitrogenase in articular tissue of HLA-B27 positive reactive patients with ankylosing spondylitis. Arthritis Rheum 1989; 32:437-45.
  • Fielder M, Pirt J, Tarpey, et al. Molecular mimicry and ankylosing spondylitis: possible role of a novel sequence in pullulanase of Klebsiella pneumoniae. FEBS Letters 1995; 369:243-8.
  • Finegold SM, Sutter VL, Sugihara P, et al. Fecal microbial flora in Seventh Day Adventist populations and control subjects. Am J Clin Nut 1977; 30:1787-92.
  • Ebringer A, Wilson C. The use of a low starch diet in the treatment of patients suffering from ankylosing spondylitis. Clin Rheum 1996; 15:62-6.
  • Adelmann M, Wood J, Benzel I, et al. The N-terminal of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat. J Neuroimm 1995; 63:17-27.
  • Swanborg RH. Experimental autoimmune encephalomyelitis in rodents as a model for human demyelinating disease. Clin Immunol Immunoneur 1995; 77:4-13.
  • Eylar E, Caccam J, Westall FC, et al. Experimental allergic encephalomyelitis synthesis of disease-in-ducing site of the basic protein. Science 1970; 168:1220-3.
  • Prineas J, Raine CS, Wisniewski It. An ultrastructural study of experimental demyelination and remyelination. III. Chronic experimental allergic encephalomyelitis in the central nervous system. Lab Invest 1969; 21:472--83.
  • Raine CS, Snyder DH, Valsamis MP, et al. Chronic experimental allergic encephalomyelitis in inbred guinea pigs. An ultrastructural study. Lab Invest 1974; 31:369-80.
  • Richard P, Ostre C, Auxoux-Cheve M. Neurophysiological follow-up in two children with Creutzfeldt-Jakob disease after human growth hormone treatment. Electroencephalogr Clin Neurophysiol 1994; 91:100-7.
  • Ellis CJ, Katifi It, Weller O. A further British case of growth hormone induced Creutzfeldt-Jakob disease. J Neurol Neurosurg Psychiatry 1992; 55:1200-2.
  • Ebringer A, Pirt J, Wilson C, et al. Bovine spongiform encephalopathy (BSE): could be an autoimmune disease produced by bacteria showing 'molecular mimicry' with bovine/ovine brain antigens. Immunology Letters 1997; 56:312-13.
  • Ebringer A, Pirt J, Wilson C, et al. Bovine spongiform encephalopathy (BSE) is it an autoimmune disease due to bacteria showing molecular mimicry with brain antigens. Environmental Health Perspect 1997; 105:1172-4.
  • Ebringer A, Pirt J, Wilson C. Is BSE an autoimmune disease? Immunology News 1997; 4:149-50.
  • Popper K. Objective Knowledge--An Evolutionary ApproachOxford: Clarendon, 1972.

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