686
Views
28
CrossRef citations to date
0
Altmetric
Original Articles

Barriers to antipsychotic discontinuation in nursing homes: an exploratory study

, , &
Pages 346-353 | Received 19 Apr 2013, Accepted 31 Jul 2013, Published online: 09 Sep 2013

References

  • Azermai, M., Elseviers, M., Petrovic, M., van Bortel, L., & Vander Stichele, R.H. (2011). Assessment of antipsychotic prescribing in Belgian nursing homes. International Psychogeriatric, 23, 1240–1248.
  • Azermai, M., Petrovic, M., Elseviers, M.M., Bourgeois, J., Van Bortel, L.M., & Vander Stichele, R.H. (2012). Systematic appraisal of dementia guidelines for the management of behavioural and psychological symptoms. Ageing Research Reviews, 11(1), 78–86.
  • Azermai, M., Petrovic, M., Engelborghs, S., Elseviers, M.M., Van der Mussele, S., Debruyne, H., … Vander Stichele, R.H. (2013). The effects of abrupt antipsychotic discontinuation in cognitively impaired older persons: A pilot study. Aging & Mental Health, 17(1), 125–132.
  • Ballard, C., Creese, B., Corbett, A., & Aarsland, D. (2011). Atypical antipsychotics for the treatment of behavioral and psychological symptoms in dementia, with a particular focus on longer term outcomes and mortality. Expert Opinion on Drug Safety, 10, 35–43.
  • Ballard, C., Lana, M.M., Theodoulou, M., Douglas, S., McShane, R., Jacoby, R., … Juszczak, E. (2008). A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics (the DART-AD trial). PLoS Medicine, 5, e76.
  • Banerjee S. (2009). The use of antipsychotic medication for people with dementia: Time for action. A report for the Minister of State for Care Services, Department of Health.
  • Briesacher, B.A., Limcangco, M.R., Simoni-Wastila, L., Doshi, J.A., Levens, S.R., Shea, D.G., & Stuart B. (2005). The quality of antipsychotic drug prescribing in nursing homes. Archives of Internal Medicine, 165, 1280–1285.
  • Bronskill, S.E., Anderson, G.M., Sykora, K., Wodchis, W.P., Gill, S., Shulman, K.I., & Rochon P.A. (2004). Neuroleptic drug therapy in older adults newly admitted to nursing homes: Incidence, dose, and specialist contact. Journal of the American Geriatrics Society, 52, 749–755.
  • Brookmeyer, R., Johnson, E., Ziegler-Graham, K., & Arrighi, H.M. (2007). Forecasting the global burden of Alzheimer's disease. Alzheimer's & Dementia, 3, 186–191.
  • Burke, A.D., & Tariot, P.N. (2009). Atypical antipsychotics in the elderly: A review of therapeutic trends and clinical outcomes. Expert Opinion on Pharmacotherapy, 10, 2407–2414.
  • Cody, M., Beck, C., & Svarstad, B.L. (2002). Challenges to the use of nonpharmacologic interventions in nursing homes. Psychiatric Services, 53, 1402–1406.
  • Cohen-Mansfield, J., Lipson, S., Werner, P., Billig, N., Taylor, L., & Woosley, R. (1999). Withdrawal of haloperidol, thioridazine, and lorazepam in the nursing home: A controlled, double-blind study. Archives of Internal Medicine, 159, 1733–1740.
  • Cornege-Blokland, E., Kleijer, B.C., Hertogh, C.M., & van Marum, R.J. (2012). Reasons to prescribe antipsychotics for the behavioral symptoms of dementia: A survey in Dutch nursing homes among physicians, nurses, and family caregivers. Journal of the American Medical Directors Association, 13, 80–86.
  • Declercq, T., Petrovic, M., Azermai, M., Van der Stichele, R., De Sutter, A.I., van Driel, M.L., & Christiaens, T. (2013). Withdrawal versus continuation of antipsychotics for behavioural and psychological symptoms in older people with dementia. Cochrane Database of Systematic Reviews, 3, CD007726. doi:10.1002/14651858.CD007726.pub2
  • Devanand, D.P., & Schultz, S.K. (2011). Consequences of antipsychotic medications for the dementia patient. American Journal of Psychiatry, 168(8), 767–769.
  • European Medicine Agency (EMA). (2004). Public statement on the safety of Olanzapine. Retrieved from http://www.bfarm.de/SharedDocs/1_Downloads/DE/Pharmakovigilanz/am-sicher-akt/emea-zyprexa-st.pdf?__blob=publicationFile
  • Katz, S., & Akpom, C.A. (1976). A measure of primary sociobiological functions. International Journal of Health Services, 6, 493–508.
  • Lyketsos, C.G., Lopez, O., Jones, B., Fitzpatrick, A.L., Breitner, J., & DeKosky, S. (2002). Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: Results from the cardiovascular health study. Journal of the American Medical Association, 288, 1475–1483.
  • Medicines and Healthcare Products Regulatory Agency (MHRA). (2008). Conventional typical antipsychotics: Increased mortality in dementia. Retrieved from http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate/CON087985
  • Medicines and Healthcare products Regulatory Agency (MHRA). (2009). Antipsychotics: Use in elderly people with dementia. Retrieved from http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate/CON088116
  • Powell, R., & Single, H. (1996). Methodology matters - V: Focus groups. International Journal for Quality in Health Care, 8(5), 499–504.
  • Reisberg, B., Borenstein, J., Salob, S.P., Ferris, S.H., Franssen, E., & Georgotas, A. (1987). Behavioral symptoms in Alzheimer's disease: Phenomenology and treatment. Journal of Clinical Psychiatry, 48 (Suppl), 9–15.
  • Ruths, S., Straand, J., Nygaard, H.A., & Aarsland, D. (2008). Stopping antipsychotic drug therapy in demented nursing home patients: A randomized, placebo-controlled study – the Bergen District Nursing Home Study (BEDNURS). International Journal of Geriatric Psychiatry, 23, 889–895.
  • Schneider, L.S., Dagerman, K.S., & Insel, P. (2005). Risk of death with atypical antipsychotic drug treatment for dementia: Meta-analysis of randomized placebo-controlled trials. Journal of the American Medical Association, 294, 1934–1943.
  • Sterke C.S., van Beeck E.F., van der Velde N., Ziere G., Petrovic M., Looman C.W., & van der Cammen T.J. (2012). New insights: Dose-response relationship between psychotropic drugs and falls: A study in nursing home residents with dementia. Journal of Clinical Pharmacology, 52(6), 947–955.
  • US Food and Drug Administration (FDA). (2005). Public health advisory: Deaths with antipsychotics in elderly patients with behavioral disturbances. Retrieved from http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationfor PatientsandProviders/DrugSafetyInformationforHeathcare Professionals/PublicHealthAdvisories/UCM053171
  • US Food and Drug Administration (FDA). (2008). Antipsychotics are not indicated for the treatment of dementia-related psychosis. Retrieved from http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm124830.htm

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.