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Original Articles

The use of psychotropic drugs for behavioral and psychological symptoms of dementia among residents in long-term care facilities in Japan

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Pages 1248-1255 | Received 23 May 2016, Accepted 01 Aug 2016, Published online: 01 Sep 2016

References

  • American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, fifth edition (DSM-5). Arlington, VA: Author.
  • Arai, A., Katsumata, Y., Konno, K., & Tamashiro, H. (2004). Sociodemographic factors associated with incidence of dementia among senior citizens of a small town in Japan. Care Management Journals, 5(3), 159–165. doi:10.1891/cmaj.2004.5.3.159
  • Arai, Y., Kumamoto, K., Washio, M., Ueda, T., Miura, H., & Kudo, K. (2004). Factors related to feelings of burden among caregivers looking after impaired elderly in Japan under the Long-Term Care insurance system. Psychiatry and Clinical Neurosciences, 58, 396–402. doi:10.1111/j.1440-1819.2004.01274.x
  • Arai, A., Ozaki, T., & Katsumata, Y. (2016). Behavioral and psychological symptoms of dementia in older residents in long-term care facilities in Japan: A cross-sectional study. Aging & Mental Health. Advance online publication. doi:10.1080/13607863.2016.1199013
  • Azermai, M. (2015). Dealing with behavioral and psychological symptoms of dementia: A general overview. Psychology Research and Behavior Management, 8, 181. doi:10.2147/PRBM.S44775
  • Azermai, M., Vander Stichele, R.R.H., Van Bortel, L.M., & Elseviers, M.M. (2014). Barriers to antipsychotic discontinuation in nursing homes: An exploratory study. Aging & Mental Health, 18, 346–353. doi:10.1080/13607863.2013.832732
  • Barnes, T.R.E., & Paton, C. (2011). Antipsychotic polypharmacy in schizophrenia: Benefits and risks. CNS Drugs, 25, 383–399. doi:10.2165/11587810-000000000-00000
  • Brodaty, H., & Arasaratnam, C. (2012). Meta-analysis of nonpharmacological interventions for neuropsychiatric symptoms of dementia. The American Journal of Psychiatry, 169, 946–953. doi:10.1176/appi.ajp.2012.11101529
  • Cerejeira, J., Lagarto, L., & Mukaetova-Ladinska, E.B. (2012). Behavioral and psychological symptoms of dementia. Frontiers in Neurology, 3, 73. doi:10.3389/fneur.2012.00073
  • Cummings, J.L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D.A., & Gornbein, J. (1994). The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology, 44, 2308–2314.
  • de Oliveira, A.M., Radanovic, M., de Mello, P.C.H., Buchain, P.C., Vizzotto, A.D.B., Celestino, D.L., … Forlenza, O.V. (2015). Nonpharmacological interventions to reduce behavioral and psychological symptoms of dementia: A systematic review. BioMed Research International, 2015, 218980. doi:10.1155/2015/218980
  • Draper, B., Brodaty, H., Low, L.F., Saab, D., Lie, D., Richards, V., & Paton, H. (2001). Use of psychotropics in Sydney nursing homes: Associations with depression, psychosis, and behavioral disturbances. International Psychogeriatrics, 13, 107–120.
  • Foebel, A.D., Liperoti, R., Onder, G., Finne-Soveri, H., Henrard, J.C., Lukas, A., … Bernabei, R. (2014). Use of antipsychotic drugs among residents with dementia in European long-term care facilities: Results from the SHELTER study. Journal of the American Medical Directors Association, 15, 911–917. doi:10.1016/j.jamda.2014.07.012
  • Furukawa, K., Tomita, N., Uematsu, D., Okahara, K., Shimada, H., Ikeda, M., … Arai, H. (2015). Randomized double-blind placebo-controlled multicenter trial of Yokukansan for neuropsychiatric symptoms in Alzheimer's disease. Geriatrics & Gerontology International. Advance online publication. doi:10.1111/ggi.12696
  • Imai, Y., Osada, H., Homma, A., Kayama, M., Mikami, Y., Kato, S., … Handa, S. (2011). Two new assessment scales for ADL and behavioral and psychological symptoms of persons of suffering from cognitive impairment. [Abstract only in English]. Japanese Journal of Geriatric Psychiatry, 22(10), 1155–1165.
  • Iwasaki, K., Satoh-Nakagawa, T., Maruyama, M., Monma, Y., Nemoto, M., Tomita, N., … Sasaki, H. (2005). A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients. The Journal of Clinical Psychiatry, 66, 248–252.
  • Jokanovic, N., Tan, E.C.K., Dooley, M.J., Kirkpatrick, C.M., Elliott, R.A., & Bell, J.S. (2016). Why is polypharmacy increasing in aged care facilities? The views of Australian health care professionals. Journal of Evaluation in Clinical Practice. Advance online publication. doi:10.1111/jep.12514
  • Kaufer, D.I., Cummings, J.L., Ketchel, P., Smith, V., MacMillan, A., Shelley, T., … DeKosky, S.T. (2000). Validation of the NPI-Q, a brief clinical form of the neuropsychiatric inventory. Journal of Neuropsychiatry and Clinical Neurosciences, 12, 233–239. doi:10.1176/jnp.12.2.233
  • Kitamura, T., Kitamura, M., Hino, S., Tanaka, N., & Kurata, K. (2012). Gender differences in clinical manifestations and outcomes among hospitalized patients with behavioral and psychological symptoms of dementia. Journal of Clinical Psychiatry, 73, 1548–1554. doi:10.4088/JCP.11m07614
  • Liu, S., Jin, Y., Shi, Z., Huo, Y.R., Guan, Y., Liu, M., … Ji, Y. (2016). The effects of behavioral and psychological symptoms on caregiver burden in frontotemporal dementia, Lewy body dementia, and Alzheimer's disease: Clinical experience in China. Aging & Mental Health. Advance online publication. doi:10.1080/13607863.2016.1146871
  • Mangone, C.A., Sanguinetti, R.M., Baumann, P.D., Gonzalez, R.C., Pereyra, S., Bozzola, F.G., … Sica, R.E. (1993). Influence of feelings of burden on the caregiver's perception of the patient's functional status. Dementia, 4, 287–293.
  • Margallo-Lana, M., Swann, A., O'Brien, J., Fairbairn, A., Reichelt, K., Potkins, D., … Ballard, C. (2001). Prevalence and pharmacological management of behavioural and psychological symptoms amongst dementia sufferers living in care environments. International Journal of Geriatric Psychiatry, 16, 39–44.
  • Matsuda, Y., Kishi, T., Shibayama, H., & Iwata, N. (2013). Yokukansan in the treatment of behavioral and psychological symptoms of dementia: A systematic review and meta-analysis of randomized controlled trials. Human Psychopharmacology, 28(1), 80–86. doi:10.1002/hup.2286
  • Matsumoto, N., Ikeda, M., Fukuhara, R., Hyodo, T., Ishikawa, T., Mori, T., … Hirono, N. (2006). Nihongo ban NPI-D to NPI-Q no datosei to shinraisei no kento. [Validity and reliability of the Japanese version of the Neuropsychiatric Inventory Caregiver Distress Scale (NPI D) and the Neuropsychiatric Inventory Brief Questionnaire Form (NPI-Q)]. Nō To Shinkei = Brain and Nerve, 58, 785–790.
  • Ministry of Health, Labour and Welfare. (2013). The current situation and the future direction of the Long-term Care Insurance System in Japan: With a focus on the housing for the elderly. Retrieved from http://www.mhlw.go.jp/english/policy/care-welfare/care-welfare-elderly/dl/ri_130311-01.pdf
  • Ministry of Health, Labour and Welfare. (1993). Ninchisho koreisha no nichijo seikatsu jiritsudo hantei kijun [Screening judgement of the level of independence in daily life for the elderly with dementia]. (Notice No.135 of the Health and Welfare Bureau for the Elderly). Tokyo: Ministry of Health, Labour and Welfare.
  • Mioshi, E., Foxe, D., Leslie, F., Savage, S., Hsieh, S., Miller, L., … Piguet, O. (2013). The impact of dementia severity on caregiver burden in frontotemporal dementia and Alzheimer disease. Alzheimer Disease and Associated Disorders, 27, 68–73. doi:10.1097/WAD.0b013e318247a0bc
  • Mohamed, S., Rosenheck, R., Lyketsos, C.G., Kaczynski, R., Sultzer, D.L., & Schneider, L.S. (2012). Effect of second-generation antipsychotics on caregiver burden in Alzheimer's disease. Journal of Clinical Psychiatry, 73, 121–128. doi:10.4088/JCP.10m06574
  • Okamoto, H., Iyo, M., Ueda, K., Han, C., Hirasaki, Y., & Namiki, T. (2014). Yokukan-san: A review of the evidence for use of this Kampo herbal formula in dementia and psychiatric conditions. Neuropsychiatric Disease and Treatment, 10, 1727–1742. doi:10.2147/NDT.S65257
  • Okumura, Y., Togo, T., & Fujita, J. (2015). Trends in use of psychotropic medications among patients treated with cholinesterase inhibitors in Japan from 2002 to 2010. International Psychogeriatrics, 27, 407–415. doi:10.1017/S1041610214001975
  • Pitkala, K.H., Laurila, J.V., Strandberg, T.E., & Tilvis, R.S. (2004). Behavioral symptoms and the administration of psychotropic drugs to aged patients with dementia in nursing homes and in acute geriatric wards. International Psychogeriatrics, 16, 61–74.
  • R Core Team. (2015). R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing. Retrieved from https://www.R-project.org/
  • Reisberg, B., Ferris, S.H., Anand, R., Leon, M.J.D., Schneck, M.K., Buttinger, C., & Borenstein, J. (1984). Functional staging of dementia of the Alzheimer type. Annals of the New York Academy of Sciences, 435, 481–483.
  • Ryden, M.B., Feldt, K.S., Oh, H.L., Brand, K., Warne, M., Weber, E., … Gross, C. (1999). Relationships between aggressive behavior in cognitively impaired nursing home residents and use of restraints, psychoactive drugs, and secured units. Archives of Psychiatric Nursing, 13(4), 170–178.
  • Schreiner, A.S. (2001). Aggressive behaviors among demented nursing home residents in Japan. International Journal of Geriatric Psychiatry, 16, 209–215.
  • Selbæk, G., Engedal, K., & Bergh, S. (2013). The prevalence and course of neuropsychiatric symptoms in nursing home patients with dementia: A systematic review. Journal of the American Medical Directors Association, 14, 161–169. doi:10.1016/j.jamda.2012.09.027
  • Selbæk, G., Kirkevold, Ø., & Engedal, K. (2007). The prevalence of psychiatric symptoms and behavioural disturbances and the use of psychotropic drugs in Norwegian nursing homes. International Journal of Geriatric Psychiatry, 22, 843–849. doi:10.1002/gps.1749
  • Snowdon, J., Day, S., & Baker, W. (2005). Why and how antipsychotic drugs are used in 40 Sydney nursing homes. International Journal of Geriatric Psychiatry, 20, 1146–1152. doi:10.1002/gps.1407
  • Snowdon, J., Galanos, D., & Vaswani, D. (2011). Patterns of psychotropic medication use in nursing homes: Surveys in Sydney, allowing comparisons over time and between countries. International Psychogeriatrics, 23, 1520–1525. doi:10.1017/S1041610211000445
  • Sørensen, L., Foldspang, A., Gulmann, N.C., & Munk-Jørgensen, P. (2001). Determinants for the use of psychotropics among nursing home residents. International Journal of Geriatric Psychiatry, 16, 147–154.
  • Taipale, H., Koponen, M., Tanskanen, A., Tolppanen, A.-M., Tiihonen, J., & Hartikainen, S. (2014). High prevalence of psychotropic drug use among persons with and without Alzheimer's disease in Finnish nationwide cohort. European Neuropsychopharmacology, 24, 1729–1737. doi:10.1016/j.euroneuro.2014.10.004
  • te Boekhorst, S., Depla, M.F.I.A., de Lange, J., Pot, A.M., & Eefsting, J.A. (2009). The effects of group living homes on older people with dementia: A comparison with traditional nursing home care. International Journal of Geriatric Psychiatry, 24, 970–978. doi:10.1002/gps.2205
  • Wetzels, R.B., Zuidema, S.U., de Jonghe, J.F.M., Verhey, F.R.J., & Koopmans, R.T.C.M. (2011). Prescribing pattern of psychotropic drugs in nursing home residents with dementia. International Psychogeriatrics, 23, 1249–1259. doi:10.1017/S1041610211000755
  • WHO Collaborating Centre for Drug Statistics Methodology. (2016). The anatomical therapeutic chemical classification system. Retrieved from http://www.whocc.no/atc_ddd_index/
  • Zuidema, S., Koopmans, R., & Verhey, F. (2007). Prevalence and predictors of neuropsychiatric symptoms in cognitively impaired nursing home patients. Journal of Geriatric Psychiatry and Neurology, 20, 41–49. doi:10.1177/0891988706292762

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