Effects of probiotic supplementation on cognitive function in elderly: A systematic review and Meta-analysis

References

• Agahi, A., Hamidi, G. A., Daneshvar, R., Hamdieh, M., Soheili, M., Alinaghipour, A., Taba, S. M. E., & Salami, M. (2019). Corrigendum: does severity of Alzheimer’s disease contribute to its responsiveness to modifying gut microbiota? A double blind clinical trial. Frontiers in Neurology, 10, 31. doi: 10.3389/fneur.2019.000
   PubMed Web of Science ®Google Scholar
• Akbari, E., Asemi, Z., Daneshvar Kakhaki, R., Bahmani, F., Kouchaki, E., Tamtaji, O. R., … Salami, M. (2016). Effect of probiotic supplementation on cognitive function and metabolic status in Alzheimer’s disease: A randomized, double-blind and controlled trial. Frontiers in Aging Neuroscience., 8, 256. https://doi.org/10.3389/fnagi.2016.00256
   PubMed Web of Science ®Google Scholar
• As’Habi, A., Nazari, M., Hajianfar, H., Arab, A., & Faghfoori, Z. (2020). A systematic review and meta-analysis of probiotic consumption and metabolic status of athletes. International Journal of Food Properties, 23(1), 941–954. https://doi.org/10.1080/10942912.2020.1772286
   Web of Science ®Google Scholar
• Benton, D., Williams, C., & Brown, A. (2007). Impact of consuming a milk drink containing a probiotic on mood and cognition. European Journal of Clinical Nutrition, 61(3), 355–361. https://doi.org/10.1038/sj.ejcn.1602546
   PubMed Web of Science ®Google Scholar
• Bhattacharjee, S., & Lukiw, W. J. (2013). Alzheimer’s disease and the microbiome. Frontiers in Cellular Neuroscience, 7, 153. https://doi.org/10.3389/fncel.2013.00153
   PubMed Web of Science ®Google Scholar
• Bonfili, L., Cecarini, V., Cuccioloni, M., Angeletti, M., Berardi, S., Scarpona, S., Rossi, G., & Eleuteri, A. M. (2018). SLAB51 probiotic formulation activates SIRT1 pathway promoting antioxidant and neuroprotective effects in an AD mouse model. Molecular Neurobiology, 55(10), 7987–8000. https://doi.org/10.1007/s12035-018-0973-4
   PubMed Web of Science ®Google Scholar
• Buford, T. W. (2017). (Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease. Microbiome, 5(1), 80. https://doi.org/10.1186/s40168-017-0296-0
   PubMed Web of Science ®Google Scholar
• Carabotti, M., Scirocco, A., Maselli, M. A., & Severi, C. (2015). The gut-brain axis: Interactions between enteric microbiota, central and enteric nervous systems. Annals of Gastroenterology, 28(2), 203–209.
   PubMed Web of Science ®Google Scholar
• Catanzaro, R., Anzalone, M., Calabrese, F., Milazzo, M., Capuana, M., Italia, A., Occhipinti, S., & Marotta, F. (2015). The gut microbiota and its correlations with the central nervous system disorders. Panminerva Medica, 57(3), 127–143.
   PubMed Web of Science ®Google Scholar
• Chung, Y.-C., Jin, H.-M., Cui, Y., Kim, D. S., Jung, J. M., Park, J.-I., Jung, E.-S., Choi, E.-K., & Chae, S.-W. (2014). Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults. Journal of Functional Foods, 10, 465–474. https://doi.org/10.1016/j.jff.2014.07.007
   Web of Science ®Google Scholar
• de Faria Barros, A., Borges, N. A., Nakao, L. S., Dolenga, C. J., do Carmo, F. L., de Carvalho Ferreira, D., Stenvinkel, P., Bergman, P., Lindholm, B., & Mafra, D. (2018). Effects of probiotic supplementation on inflammatory biomarkers and uremic toxins in non-dialysis chronic kidney patients: A double-blind, randomized, placebo-controlled trial. Journal of Functional Foods, 46, 378–383. https://doi.org/10.1016/j.jff.2018.05.018
   Web of Science ®Google Scholar
• Den, H., Dong, X., Chen, M., & Zou, Z. (2020). Efficacy of probiotics on cognition, and biomarkers of inflammation and oxidative stress in adults with Alzheimer’s disease or mild cognitive impairment - a meta-analysis of randomized controlled trials. Aging, 12(4), 4010–4039. https://doi.org/10.18632/aging.102810
   PubMedGoogle Scholar
• Eshraghi, R. S., Davies, C., Iyengar, R., Perez, L., Mittal, R., & Eshraghi, A. A. (2021). Gut-Induced inflammation during development may compromise the blood-brain barrier and predispose to autism spectrum disorder. Journal of Clinical Medicine, 10(1), 27. https://doi.org/10.3390/jcm10010027
   Web of Science ®Google Scholar
• Ferri, C. P., Prince, M., Brayne, C., Brodaty, H., Fratiglioni, L., Ganguli, M., Hall, K., Hasegawa, K., Hendrie, H., Huang, Y., Jorm, A., Mathers, C., Menezes, P. R., Rimmer, E., & Scazufca, M. (2005). Global prevalence of dementia: A Delphi consensus study. Lancet (London, England), 366(9503), 2112–2117. https://doi.org/10.1016/S0140-6736(05)67889-0
   PubMed Web of Science ®Google Scholar
• Grenham, S., Clarke, G., Cryan, J. F., & Dinan, T. G. (2011). Brain-gut-microbe communication in health and disease. Frontiers in Physiology, 2, 94–94. https://doi.org/10.3389/fphys.2011.00094
   PubMed Web of Science ®Google Scholar
• Heshmati, J., Farsi, F., Shokri, F., Rezaeinejad, M., Almasi-Hashiani, A., Vesali, S., & Sepidarkish, M. (2018). A systematic review and meta-analysis of the probiotics and synbiotics effects on oxidative stress. Journal of Functional Foods, 46, 66–84. https://doi.org/10.1016/j.jff.2018.04.049
   Web of Science ®Google Scholar
• Higgins, J. P. T., Altman, D. G., Gøtzsche, P. C., Jüni, P., Moher, D., Oxman, A. D., Savovic, J., Schulz, K. F., Weeks, L., & Sterne, J. A. C. (2011). The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ (Clinical Research ed.), 343, d5928. https://doi.org/10.1136/bmj.d5928
   PubMed Web of Science ®Google Scholar
• Higgins, J. P., & Green, S. (2011). Cochrane handbook for systematic reviews of interventions (Vol. 4). John Wiley & Sons.
   Google Scholar
• Hu, X., Wang, T., & Jin, F. (2016). Alzheimer’s disease and gut microbiota. Science China. Life Sciences, 59(10), 1006–1023. https://doi.org/10.1007/s11427-016-5083-9
   PubMed Web of Science ®Google Scholar
• Hwang, Y. H., Park, S., Paik, J. W., Chae, S. W., Kim, D. H., Jeong, D. G., … Chung, Y. C. (2019). Efficacy and safety of lactobacillus plantarum C29-fermented soybean (DW2009) in individuals with mild cognitive impairment: A 12-week, multi-center, randomized, double-blind, placebo-controlled clinical trial. Nutrients, 11(2), 1–14. https://doi.org/10.3390/nu11020305
   Google Scholar
• Inoue, T., Kobayashi, Y., Mori, N., Sakagawa, M., Xiao, J.-Z., Moritani, T., Sakane, N., & Nagai, N. (2018). Effect of combined bifidobacteria supplementation and resistance training on cognitive function, body composition and bowel habits of healthy elderly subjects. Beneficial Microbes, 9(6), 843–853. https://doi.org/10.3920/BM2017.0193
   PubMed Web of Science ®Google Scholar
• Ishimwe, N., Daliri, E. B., Lee, B. H., Fang, F., & Du, G. (2015). The perspective on cholesterol-lowering mechanisms of probiotics . Molecular Nutrition & Food Research, 59(1), 94–105. https://doi.org/10.1002/mnfr.201400548
   PubMed Web of Science ®Google Scholar
• Kim, C. S., Cha, L., Sim, M., Jung, S., Chun, W. Y., Baik, H. W., & Shin, D. M. (2021). Probiotic supplementation improves cognitive function and mood with changes in gut microbiota in community-dwelling elderly: A randomized, double-blind, placebo-controlled, multicenter trial. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 76(1), 32–40. https://doi.org/10.1093/gerona/glaa090
   Google Scholar
• Kobayashi, Y., Kuhara, T., Oki, M., & Xiao, J.-Z. (2019). Effects of Bifidobacterium breve A1 on the cognitive function of older adults with memory complaints: A randomised, double-blind, placebo-controlled trial. Beneficial Microbes, 10(5), 510–511. https://doi.org/10.3920/BM2018.0170
   Web of Science ®Google Scholar
• Kowalski, K., & Mulak, A. (2019). Brain-Gut-microbiota axis in Alzheimer’s disease. Journal of Neurogastroenterology and Motility, 25(1), 48–60. https://doi.org/10.5056/jnm18087
   PubMed Web of Science ®Google Scholar
• Louzada, E. R., & Ribeiro, S. M. L. (2020). Synbiotic supplementation, systemic inflammation, and symptoms of brain disorders in elders: A secondary study from a randomized clinical trial. Nutritional Neuroscience, 23(2), 93–100. https://doi.org/10.1080/1028415X.2018.1477349
   PubMed Web of Science ®Google Scholar
• Lutz, W., Sanderson, W., & Scherbov, S. (2008). The coming acceleration of global population ageing. Nature, 451(7179), 716–719. https://doi.org/10.1038/nature06516
   PubMed Web of Science ®Google Scholar
• Lynch, S. V., & Pedersen, O. (2016). The human intestinal microbiome in health and disease. The New England Journal of Medicine, 375(24), 2369–2379. https://doi.org/10.1056/NEJMra1600266
   PubMed Web of Science ®Google Scholar
• Maia, L. P., Levi, Y. L. d A. S., do Prado, R. L., Santinoni, C. d S., & Marsicano, J. A. (2019). Effects of probiotic therapy on serum inflammatory markers: A systematic review and meta-analysis. Journal of Functional Foods, 54, 466–478. https://doi.org/10.1016/j.jff.2019.01.051
   Web of Science ®Google Scholar
• Moher, D., Altman, D. G., Liberati, A., & Tetzlaff, J. (2011). PRISMA statement. Epidemiology (Cambridge, Mass.), 22(1), 128; author reply 128. https://doi.org/10.1097/EDE.0b013e3181fe7825
   PubMed Web of Science ®Google Scholar
• United Nations. (2017). World population prospects: The 2017 revision, key findings and advance tables. Department of Economics and Social Affairs PD (Eds). United Nations.
   Google Scholar
• Nimgampalle, M., & Kuna, Y. (2017). Anti-Alzheimer properties of probiotic, lactobacillus plantarum MTCC 1325 in Alzheimer’s disease induced albino rats. Journal of Clinical and Diagnostic Research : JCDR, 11(8), KC01–kc05. https://doi.org/10.7860/jcdr/2017/26106.10428
   PubMed Web of Science ®Google Scholar
• Quigley, E. M. M. (2017). Microbiota-Brain-Gut axis and neurodegenerative diseases. Curr Neurol Neurosci Rep, 17(12), 94https://doi.org/10.1007/s11910-017-0802-6
   PubMed Web of Science ®Google Scholar
• Reitz, C., Tang, M.-X., Schupf, N., Manly, J. J., Mayeux, R., & Luchsinger, J. A. (2010). A summary risk score for the prediction of Alzheimer disease in elderly persons. Arch Neurol, 67(7), 835–841. https://doi.org/10.1001/archneurol.2010.136
   PubMedGoogle Scholar
• Rendeiro, C., Guerreiro, J. D., Williams, C. M., & Spencer, J. P. (2012). Flavonoids as modulators of memory and learning: Molecular interactions resulting in behavioural effects. The Proceedings of the Nutrition Society, 71(2), 246–262. https://doi.org/10.1017/S0029665112000146
   PubMed Web of Science ®Google Scholar
• Rendeiro, C., Vauzour, D., Rattray, M., Waffo-Téguo, P., Mérillon, J. M., Butler, L. T., Williams, C. M., & Spencer, J. P. E. (2013). Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor. PLoS One., 8(5), e63535. https://doi.org/10.1371/journal.pone.0063535
   PubMed Web of Science ®Google Scholar
• Serra, D., Almeida, L. M., & Dinis, T. C. (2019). The impact of chronic intestinal inflammation on brain disorders: The microbiota-gut-brain axis. Molecular Neurobiology, 56(10), 6941–6951. https://doi.org/10.1007/s12035-019-1572-8
   PubMed Web of Science ®Google Scholar
• Tamtaji, O. R., Heidari-Soureshjani, R., Mirhosseini, N., Kouchaki, E., Bahmani, F., Aghadavod, E., Tajabadi-Ebrahimi, M., & Asemi, Z. (2019). Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer’s disease: A randomized, double-blind, controlled trial. Clinical Nutrition, 38(6), 2569–2575. https://doi.org/10.1016/j.clnu.2018.11.034
   PubMed Web of Science ®Google Scholar
• Tyler, W. J., Alonso, M., Bramham, C. R., & Pozzo-Miller, L. D. (2002). From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learning & Memory (Cold Spring Harbor, N.Y.), 9(5), 224–237. https://doi.org/10.1101/lm.51202
   PubMed Web of Science ®Google Scholar
• Wang, S-h., Huang, Y., Yuan, Y., Xia, W-q., Wang, P., & Huang, R. (2014). LDL receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapses. Lipids in Health and Disease, 13(1), 175–111. https://doi.org/10.1186/1476-511X-13-175
   PubMedGoogle Scholar
• Wang, H., Lee, I. S., Braun, C., & Enck, P. (2016). Effect of probiotics on central nervous system functions in animals and humans: A systematic review. Journal of Neurogastroenterology and Motility, 22(4), 589–605. https://doi.org/10.5056/jnm16018
   PubMed Web of Science ®Google Scholar
• Yang, D., Zhao, D., Ali Shah, S. Z., Wu, W., Lai, M., Zhang, X., Li, J., Guan, Z., Zhao, H., Li, W., Gao, H., Zhou, X., & Yang, L. (2019). The role of the gut microbiota in the pathogenesis of Parkinson’s disease. Frontiers in Neurology, 10, 1155. https://doi.org/10.3389/fneur.2019.01155
   PubMedGoogle Scholar