Association of bioavailable estradiol levels and testosterone levels with serum albumin levels in elderly men

References

• Carani C, Qin K, Simoni M, Faustini-Futini M, Serpente S, Boyd J, Korach K S, Simpson E R. Effect of testosterone and estradiol in a man with aromatase deficiency. N Engl J Med 1997; 337: 91–95
   PubMed Web of Science ®Google Scholar
• Faustini-Futini M, Rochira V, Carani C. Oestrogen deficiency in men: where are we today?. Eur J Endocrinol 1999; 140: 111–129
   PubMed Web of Science ®Google Scholar
• Grumbach M M, Auchus R J. Estrogen: consequences and implications of human mutations in synthesis and action. J Clin Endocrinol Metab 1999; 84: 4677–4694
   PubMed Web of Science ®Google Scholar
• Rochira V, Balestrieri A, Faustini-Futini M, Borgato S, Beck-Peccoz P, Carani C. Pitutary function in a man with congenital aromatase deficiency: effect of different doses of transdermal E2 on basal and stimulated pituitary hormones. J Clin Endocrinol Metab 2002; 87: 2857–2862
   PubMed Web of Science ®Google Scholar
• Swaab D F. The complex effects of sex hormones on the brain it all depends on the species, sex, age and cell type. XX vs XY 2003; 1: 3–4
   Google Scholar
• Couse J F, Korach K S. Estrogen receptor null mice: what have we learned and where will they lead us?. Endocr Rev 1999; 20: 358–417
   PubMed Web of Science ®Google Scholar
• Luconi M, Muratori M, Forti G, Baldi E. Identification and characterization of a novel functional estrogen receptor on human sperm membrane which interferes with progesterone effects. J Clin Endocrinol Metab 1999; 84: 1670–1678
   PubMed Web of Science ®Google Scholar
• Raman J D, Schlegel P N. Aromatase inhibitor for male infertility. J Urol 2002; 167: 624–629
   PubMed Web of Science ®Google Scholar
• Gray A, Berlin J, McKinlay J, Longcops C. An examination of research design effects on the association of testosterone and male aging: results of a meta-analysis. J Clin Epidemiol 1991; 44: 671–684
   PubMed Web of Science ®Google Scholar
• Vermeulen A. Androgens in the aging male. J Clin Endocrinol Metab 1991; 73: 221–224
   PubMed Web of Science ®Google Scholar
• Vermeulen A, Kaufman J M, Giagulli V A. Influence of some biological indices on sex hormone binding globulin an androgen levels in aging and obese males. J Clin Endocrinol Metab 1996; 81: 1821–1827
   PubMed Web of Science ®Google Scholar
• Vermeulen A. Androgen replacement therapy in the aging male. A critical evaluation. J Clin Endocrinol Metab 2001; 86: 2380–2390
   PubMed Web of Science ®Google Scholar
• Sternbach H. Age-associated testosterone decline in men: clinical issues for psychiatry. Am J Psychiatry 1998; 155: 1310–1318
   PubMed Web of Science ®Google Scholar
• Barrett-Connor E, Von Muhlen D G, Kritz-Silverstein D. Bioavailable testosterone and depressed mood in older men: the Rancho Bernardo Study. J Clin Endocrinol Metab 1999; 84: 573–577
   PubMed Web of Science ®Google Scholar
• Riggs B L, Melton L J, III. Involutional osteoporosis. N Engl J Med 1898; 314: 1676–1686
   Web of Science ®Google Scholar
• Gullberg B, Johnell O, Kanis J A. World-wide projections for hip fracture. Osteoporos Int 1997; 7: 407–413
   PubMed Web of Science ®Google Scholar
• Stock H, Schneider A, Strauss E. Osteoporosis: a disease in men. Clin Orthop 2004; 425: 143–151
   Web of Science ®Google Scholar
• O'Connor S, Baker H WG, Dulmanis A, Hudson B. The measurement of sex steroid binding globulin by differential ammonium sulphate precipitation. J Steroid Biochem 1973; 4: 331–339
   PubMedGoogle Scholar
• Tremblay R R, Dube J Y. Plasma concentrations of free and non-TeBG bound testosterone in women on oral contraceptives. Contraception 1974; 10: 599–605
   PubMed Web of Science ®Google Scholar
• Sodergard R, Backstrom T, Shanbhag V, Carstensen H. Calculation of free and bound fractions of testosterone and estradiol-17beta to human plasma proteins at body temperature. J Steroid Biochem 1982; 16: 801–810
   PubMedGoogle Scholar
• Manni A, Pardridge W M, Cefalu W, Nisula B C, Bardin C W, Santner S J, Santen R J. Bioavailability of albumin-bound testosterone. J Clin Endocrinol Metab 1985; 61: 705–710
   PubMed Web of Science ®Google Scholar
• Drinka P J, Olson J, Bauwens S, Voeks S, Carlson I, Wilson M. Lack of association between free testosterone and bone density in elderly men. Calcif Tissue Int 1993; 52: 67–69
   PubMed Web of Science ®Google Scholar
• Slemenda C W, Longcope C, Zhou L, Hui S L, Peacock M, Johnston C C. Sex steroids and bone mass in older men. Positive associations with serum estrogens and negative associations with androgens. J Clin Invest 1997; 100: 1755–1759
   PubMed Web of Science ®Google Scholar
• Moll G W, Jr, Rosenfield R L, Helke J H. Estradiol-testosterone binding interactions and free plasma estradiol under physiological conditions. J Clin Endocrinol Metab 1981; 52: 868–874
   PubMed Web of Science ®Google Scholar
• Bhasin S, Storer W, Berman M, Callegari C, Clevenger B, Phillips J, Lee W P, Bunnell T J, Casaburi R. The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. N Engl J Med 1996; 335: 1–7
   PubMed Web of Science ®Google Scholar
• Vermeulen A. Reflections concerning biochemical parameters of androgenicity. The Aging Male 2004; 7: 280–289
   PubMedGoogle Scholar
• Nelson J C, Tomei R. Direct determination of free thyroxin in undiluted serum by equilibrium dialysis/radioimmunoassay. Clin Chem 1988; 34: 1737–1788
   PubMed Web of Science ®Google Scholar
• Warner B A, Dufau M L, Santen R J. Effects of aging and illness on the pituitary testicular axis in men: qualitative as well as quantitative changes in luteinizing hormone. J Clin Endocrinol Metab 1985; 60: 263–268
   PubMed Web of Science ®Google Scholar
• Korenman S G, Morley J E, Mooradian A D, Davis S S, Kaiser F E, Silver A G, Viosca S P, Garza D. Secondary hypogonadism in older men: its relation to impotence. J Clin Endocrinol Metab 1990; 71: 963–969
   PubMed Web of Science ®Google Scholar
• Davidson J M, Chen J J, Crapo L, Gray G D, Greenleaf W J, Catania J A. Hormonal changes and sexual function in aging men. J Clin Endocrinol Metab 1983; 57: 71–77
   PubMed Web of Science ®Google Scholar
• Labrie F, Belanger A, Cusan L, Candas B. Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology. J Clin Endocrinol Metab 1997; 82: 2403–2409
   PubMed Web of Science ®Google Scholar
• Baker H W, Burger H G, de Kretser D M, Hudson B, O'Connor S, Wang C, Mirovics A, Court J, Dunlop M, Rennis G D. Changes in the pituitary-testicular system with age. Clin Endocrinol 1976; 5: 349–372
   PubMed Web of Science ®Google Scholar
• Khosla S, Melton L J, III, Atkinson E J, O'Fallon W M, Klee G G, Riggs B L. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab 1998; 83: 2266–2274
   PubMed Web of Science ®Google Scholar
• van den Beld A W, de Jong F H, Grobbee D E, Pols H AP, Lamberts S WJ. Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men. J Clin Endocrinol Metab 2000; 85: 3276–3282
   PubMed Web of Science ®Google Scholar
• McKane W R, Khosla S, Risteli J, Robins S P, Muhs J, Riggs B L. Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and bone turnover abnormalities in elderly women. Proc Assoc Am Physicians 1997; 109: 174–180
   PubMedGoogle Scholar
• Meier D E, Orwoll E S, Keenan E J, Fagerstrom R M. Marked decline in trabecular bone mineral content in healthy men with age: lack of association with sex steroid levels. J Am Geriatr Soc 1987; 35: 189–197
   PubMed Web of Science ®Google Scholar
• Murphy S, Khaw K-T, Cassidy A, Compston J E. Sex steroids and bone mineral density in elderly men. Bone Miner 1992; 20: 133–140
   Google Scholar
• Pardridge W M. Serum bioavailability of sex steroid hormones. J Clin Endocrinol Metab 1986; 15: 259–278
   Web of Science ®Google Scholar