The effect of short-term estradiol therapy on clotting and inflammatory markers in older men receiving hormonal suppression therapy for prostate cancer

References

• Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in post-menopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA 1998; 280: 605–613
   PubMed Web of Science ®Google Scholar
• The Women's Health Initiative Study Group. Design of the Women's Health Initiative clinical trial and observational study. Control clin Trials 1998; 19: 61–109
   PubMedGoogle Scholar
• MacDonald P C, Madden J D, Brenner P F, Wilson J D, Siiteri P K. Origin of estrogen in normal men and in women with testicular feminization. J Clin Endocrinol Metab 1979; 49: 905–916
   PubMed Web of Science ®Google Scholar
• The Coronary Drug Project Research Group. The Coronary Drug Project. Findings leading to discontinuation of the 2.5-mg day estrogen group. JAMA 1973; 226: 652–657
   PubMedGoogle Scholar
• Byar D P, Corle D. Hormone therapy for prostate cancer: results of the Veterans Administration Cooperative Urological Research Group Studies. NCI Monogram 1988; 7: 165
   PubMedGoogle Scholar
• Arnlöv J, Pencina M J, Amin S, Nam B H, Benjamin E J, Murabito J M, Wang T J, Knapp P E, D'Agostino R B, Sr, Bhasin S, Vasan R S. Endogenous sex hormones and cardiovascular disease incidence in men. Ann Intern Med 2006; 145: 176–184
   PubMed Web of Science ®Google Scholar
• Giri S, Thompson P D, Taxel P, et al. Oral estrogen improves serum lipids, homocysteine and fibrinolysis in elderly men. Atherosclerosis 1998; 137: 359–366
   PubMed Web of Science ®Google Scholar
• Taxel P, Fall P M, Albertsen P C, Dowsett R D, Trahiotis M, Zimmerman J, Ohannessian C, Raisz L G. The effect of micronized estradiol on bone turnover and calciotropic hormones in older men receiving hormonal suppression therapy for prostate cancer. J Clin Endocrinol Metab 2002; 87: 4907–4913
   PubMedGoogle Scholar
• Salobir B G, Keber I, Vrabic L. A randomized placebo-controlled trial of the effects of continuous combined hormone replacement therapy on coagulation and fibrinolytic systems in healthy postmenopausal women. Fertil Steril 2002; 78: 1178–1183
   PubMedGoogle Scholar
• Stork S, van der Schouw Y T, Grobbee D E, Bots M L. Estrogen, inflammation and cardiovascular risk in women: a critical appraisal. Trends in Endocrinol and Metab 2004; 15(2)66–72
   PubMedGoogle Scholar
• Wald D S, Law M, Morris J K. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002; 325: 1202
   PubMed Web of Science ®Google Scholar
• Dimitrova K R, DeGroot K, Myers A K, Kim Y D. Estrogen and homocysteine. Cardiovasc Res 2002; 53: 577–588
   PubMed Web of Science ®Google Scholar
• Yildirir A, Aybar F, Tokgozoglu L, Yarali H, Kabakci G, Bukulmez O, Sinici I, Oto A. Effects of hormone replacement therapy on plasma homocysteine and C-reactive protein levels. Gynecol Obstet Invest 2002; 53: 54–58
   PubMed Web of Science ®Google Scholar
• Walsh B W, Paul S, Wild R A, Dean R A, Tracy R P, Cox D A, Anderson P W. The effects of hormone replacement therapy and raloxifene on C-reactive protein and homocysteine in healthy postmenopausal women: a randomized, controlled study. J Clin Endocrinol Metab 2000; 85: 214–218
   PubMed Web of Science ®Google Scholar
• Hak A E, Bak A A, Lindemans J, Planellas J, Coelingh Bennink H, Hofman A, Grobbee D, Witteman J C. The effect of hormone replacement therapy on serum homocysteine levels in perimenopausal women: a randomized controlled trial. Atherosclerosis 2001; 158: 437–443
   PubMed Web of Science ®Google Scholar
• Madsen J S, Kristensen S R, Klitgaard N A, Bladbjerg E M, Abrahamsen B, Stilgren L, Jespersen J. Effect of long-term hormone replacement therapy on plasma homocysteine in postmenopausal women: a randomized controlled study. Am J Obstet Gynecol 2002; 187: 33–39
   PubMed Web of Science ®Google Scholar
• Giltay E J, Verhoef P, Gooren L J, Geleijnse J M, Schouten E G, Stehouwer C DA. Oral and transdermal estrogens both lower plasma total homocysteine in male-to-female transsexuals. Atherosclerosis 2003; 168(1)139–146
   PubMedGoogle Scholar
• Giltay E J, Hoogeveen E K, Elbers J MH, Gooren L JG, Asscheman H, Stehouwer C DA. Effects of sex steroids on plasma total homocysteine levels: a study in transsexual males and females. J Clin Endocrinol Metab 1998; 83: 550–553
   PubMedGoogle Scholar
• Pai J K, Pischon T, Ma J, Manson J E, Hankinson S E, Joshipura K, Curhan G C, Rifai N, Cannuscio C C, Stampfer M J, Rimm E B. Inflammatory markers and the risk of coronary heart disease in men and women. N Eng J Med 2004; 351: 2599–2610
   PubMed Web of Science ®Google Scholar
• Ng M K, Liu P Y, Williams A J, Nakhla S, Ly L P, Handelsman D J, Celermajer D S. Prospective study of effect of androgens on serum inflammatory markers in men. Arterioscler Thromb Vasc Biol 2002; 22: 1136–1141
   PubMed Web of Science ®Google Scholar
• Cushman M, Legault C, Barrett-Connor E, Stefanick M L, Kessler C, Judd H L, Sakkinen P A, Tracy R P. Effect of postmenopausal hormones on inflammation-sensitive proteins: the Postmenopausal Estrogen/Progestin Interventions (PEPI) Study. Circulation 1999; 100: 717–722
   PubMed Web of Science ®Google Scholar
• Prestwood K M, Unson C, Kulldorff M, Cushman M. The effect of different doses of micronized 17beta-estradiol on C-reactive protein, interleukin-6, and lipids in older women. J Gerontol A Biol Sci Med Sci 2004; 59(8)827–832
   PubMedGoogle Scholar
• Teede H J, McGarth B P, Smolich J J, Malan E, Kotsopoulos D, Liang Y, Peverill R E. Postmenopausal hormone replacement therapy increases coagulation activity and fibrinolysis. Arterioscler Thromb Vasc Biol 2000; 20: 1404–1409
   PubMed Web of Science ®Google Scholar
• Kroon U B, Silfverstolpe G, Tengborn L. The effects of transdermal estradiol and oral conjugated estrogens on haemostasis variables. Thromb haemost 1994; 71: 420–423
   PubMedGoogle Scholar
• Koh K K, Mincemoyer R, Minh N B, Csako G, Pucino F, Guetta V, Waclawiw M, Cannon R. Effects of hormone replacement therapy on fibrinolysis in postmenopausal women. N Engl J Endocrinol 1997; 336: 683–690
   Google Scholar
• Wilson R, Jenkins C, Miller H, Carr S. The effect of oestrogen on cytokine and antioxidant levels in male to female transsexual patients. Maturitas 2006; 55(1)14–18
   PubMedGoogle Scholar
• Straub R, Hense H, Andus J, Schölmerich J, Riegger G, Schunkert H. Effect of oestrogen replacement on bone metabolism and cytokines in surgical menopause. J Clin Endocrinol Metab 2000; 85: 1340–1344
   PubMed Web of Science ®Google Scholar
• Scheidt-Nave C, Bismar H, Leidig-Bruckner G, Woitge H, Seibel M, Ziegler R, Pfeilschifter J. Serum interleukin-6 is a major predictor of bone loss in women specific to the first decade past menopause. J Clin Endocrinol Metab 2001; 86: 2031–2042
   Google Scholar