Clinical trial of treatment with saikokaryukotsuboreito for eugonadal patients with late-inset hypogonadism-related symptoms

References

• Morales A, Lunenfeld B. Investigation, treatment and monitoring of late-onset hypogonadism in males. Official recommendations of ISSAM. International Society for the Study of the Aging Male. Aging Male 2002; 5: 74–86
   PubMedGoogle Scholar
• Morley J E. Androgens and aging. Maturitas 2001; 38: 61–71, discussion 71–63
   PubMed Web of Science ®Google Scholar
• Morales A, Buvat J, Gooren L J, Guay A T, Kaufman J M, Tan H M, Torres L O. Endocrine aspects of sexual dysfunction in men. J Sex Med 2004; 1: 69–81
   PubMed Web of Science ®Google Scholar
• Morley J E, Perry H M, III. Androgen deficiency in aging men. Med Clin North Am 1999; 83: 1279–1289, vii
   PubMed Web of Science ®Google Scholar
• Vermeulen A. Andropause. Maturitas 2000; 34: 5–15
   PubMed Web of Science ®Google Scholar
• Morales A, Heaton J P, Carson C C, III. Andropause: A misnomer for a true clinical entity. J Urol 2000; 163: 705–712
   PubMed Web of Science ®Google Scholar
• Tsujimura A, Matsumiya K, Matsuoka Y, Takahashi T, Koga M, Iwasa A, Takeyama M, Okuyama A. Bioavailable testosterone with age and erectile dysfunction. J Urol 2003; 170: 2345–2347
   PubMed Web of Science ®Google Scholar
• Morley J E. Testosterone replacement and the physiologic aspects of aging in men. Mayo Clin Proc 2000; 75: S83–87
   PubMedGoogle Scholar
• Morley J E. Testosterone replacement in older men and women. J Gend Specif Med 2001; 4: 49–53
   PubMedGoogle Scholar
• Morley J E, Perry H M, III. Androgen treatment of male hypogonadism in older males. J Steroid Biochem Mol Biol 2003; 85: 367–373
   PubMed Web of Science ®Google Scholar
• Comhaire F H. Andropause: Hormone replacement therapy in the ageing male. Eur Urol 2000; 38: 655–662
   PubMed Web of Science ®Google Scholar
• Morales A, Johnston B, Heaton J P, Lundie M. Testosterone supplementation for hypogonadal impotence: Assessment of biochemical measures and therapeutic outcomes. J Urol 1997; 157: 849–854
   PubMed Web of Science ®Google Scholar
• T'Sjoen G, Feyen E, De Kuyper P, Comhaire F, Kaufman J M. Self-referred patients in an aging male clinic: Much more than androgen deficiency alone. Aging Male 2003; 6: 157–165
   PubMedGoogle Scholar
• T'Sjoen G, Goemaere S, De Meyere M, Kaufman J M. Perception of males' aging symptoms, health and well-being in elderly community-dwelling men is not related to circulating androgen levels. Psychoneuroendocrinology 2004; 29: 201–214
   PubMed Web of Science ®Google Scholar
• Tsujimura A, Matsumiya K, Miyagawa Y, Takao T, Fujita K, Takada S, Koga M, Iwasa A, Takeyama M, Okuyama A. Comparative study on evaluation methods for serum testosterone level for PADAM diagnosis. Int J Impot Res 2005; 17: 259–263
   PubMed Web of Science ®Google Scholar
• Miwa Y, Kaneda T, Yokoyama O. Correlation between the Aging Males' Symptoms Scale and sex steroids, gonadotropins, dehydroepiandrosterone sulfate, and growth hormone levels in ambulatory men. J Sex Med 2006; 3: 723–726
   PubMed Web of Science ®Google Scholar
• Chen J T, Shiraki M. Menopausal hot flash and calciotonin gene-related peptide; Effect of Keishi-bukuryo-gan, a kampo medicine, related to plasma calciotonin gene-related peptide level. Maturitas 2003; 45: 199–204
   PubMedGoogle Scholar
• Ushiroyama T, Ikeda A, Sakuma K, Ueki M. Changes in serum tumor necrosis factor (TNF-alpha) with kami-shoyo-san administration in depressed climacteric patients. Am J Chin Med 2004; 32: 621–629
   PubMedGoogle Scholar
• Heinemann L A, Zimmermann T, Vermeulen A, Thiel C. A new ‘aging males' symptoms' (AMS) rating scale. Aging Male 1999; 2: 105–114
   Google Scholar
• Zung W W, Richards C B, Short M J. Self-rating depression scale in an outpatient clinic. Further validation of the SDS. Arch Gen Psychiatry 1965; 13: 508–515
   PubMed Web of Science ®Google Scholar
• Barry M J, Fowler F J, Jr, O'Leary M P, Bruskewitz R C, Holtgrewe H L, Mebust W K, Cockett A T. The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. J Urol 1992; 148: 1549–1557, discussion 1564
   PubMed Web of Science ®Google Scholar
• Kelleher C J, Cardozo L D, Khullar V, Salvatore S. A new questionnaire to assess the quality of life of urinary incontinent women. Br J Obstet Gynaecol 1997; 104: 1374–1379
   PubMedGoogle Scholar
• Yoshida N M, Kumano H, Kuboki T. Does the Aging Males' Symptoms scale assess major depressive disorder? A pilot study. Maturitas 2006; 53: 171–175
   PubMed Web of Science ®Google Scholar
• Sato Y, Tanda H, Kato S, Onishi S, Nakajima H, Nanbu A, Nitta T, Koroku M, Akagashi K, Hanzawa T. Prevalence of major depressive disorder in self-referred patients in a late onset hypogonadism clinic. Int J Impot Res 2007; 19: 407–410
   PubMedGoogle Scholar
• Pittler M H, Ernst E. Kava extract for treating anxiety. Cochrane Database Syst Rev 2003, CD003383
   PubMedGoogle Scholar
• Shevtsov V A, Zholus B I, Shervarly V I, Vol'skij V B, Korovin Y P, Khristich M P, Roslyakova N A, Wikman G. A randomized trial of two different doses of a SHR‐5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine 2003; 10: 95–105
   PubMed Web of Science ®Google Scholar
• Ushiroyama T, Ikeda A, Sakuma K, Ueki M. Chai-hu-gui-zhi-gan-jiang-tang regulates plasma interleukin-6 and soluble interleukin-6 receptor concentrations and improves depressed mood in climacteric women with insomnia. Am J Chin Med 2005; 33: 703–711
   PubMedGoogle Scholar
• Pan B, Kato Y, Sengoku K, Takuma N, Niizeki N, Ishikawa M. Treatment of climacteric symptoms with herbal formulas of traditional Chinese medicine. Gynecol Obstet Invest 2004; 57: 144–148
   PubMedGoogle Scholar
• Park S W, Kim Y K, Lee J G, Kim S H, Kim J M, Yoon J S, Park Y K, Lee Y K, Kim Y H. Antidepressant-like effects of the traditional Chinese medicine kami-shoyo-san in rats. Psychiatry Clin Neurosci 2007; 61: 401–406
   PubMed Web of Science ®Google Scholar
• Saltzman E A, Guay A T, Jacobson J. Improvement in erectile function in men with organic erectile dysfunction by correction of elevated cholesterol levels: A clinical observation. J Urol 2004; 172: 255–258
   PubMed Web of Science ®Google Scholar
• Nomura S, Hattori N, Sakakibara I, Fukuhara S. Effects of Saiko-ka-ryukotsu-borei-to in patients with hyperlipidemia. Phytomedicine 2001; 8: 165–173
   PubMedGoogle Scholar
• Sarai K. Oriental medicine as therapy for resistant depression: Use of some herbal drugs in the Far East (Japan). Prog Neuropsychopharmacol Biol Psychiatry 1992; 16: 171–180
   PubMedGoogle Scholar
• Kanba S, Yamada K, Mizushima H, Asai M. Use of herbal medicine for treating psychiatric disorders in Japan. Psychiatry Clin Neurosci 1998; 52: S331–333
   PubMedGoogle Scholar
• Sasaki K, Suzuki K, Yoshizaki F, Ando T. Effect of saiko-ka-ryukotsu-borei-to on the stress-induced increase of serum corticosterone in mice. Biol Pharm Bull 1995; 18: 563–565
   PubMedGoogle Scholar
• Mizoguchi K, Yuzurihara M, Ishige A, Sasaki H, Tabira T. Saiko-ka-ryukotsu-borei-to, an herbal medicine, prevents chronic stress-induced disruption of glucocorticoid negative feedback in rats. Life Sci 2002; 72: 67–77
   PubMed Web of Science ®Google Scholar
• Mizoguchi K, Yuzurihara M, Ishige A, Aburada M, Tabira T. Saiko-ka-ryukotsu-borei-to, a herbal medicine, ameliorates chronic stress-induced depressive state in rotarod performance. Pharmacol Biochem Behav 2003; 75: 419–425
   PubMed Web of Science ®Google Scholar
• Tenover J S. Effects of testosterone supplementation in the aging male. J Clin Endocrinol Metab 1992; 75: 1092–1098
   PubMed Web of Science ®Google Scholar
• Tsujimura A, Matsumiya K, Takao T, Miyagawa Y, Takada S, Koga M, Iwasa A, Takeyama M, Okuyama A. Treatment with human chorionic gonadotropin for PADAM: A preliminary report. Aging Male 2005; 8: 175–179
   PubMedGoogle Scholar