The impact of age, BMI and sex hormone on aging males’ symptoms and the international index of erectile function scores

References

• NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA. 1993;270:83–90.
   PubMed Web of Science ®Google Scholar
• Kong XB, Guan HT, Li HG, et al. The ageing males' symptoms scale for Chinese men: reliability,validation and applicability of the Chinese version. Andrology. 2014;2:856–861.
   PubMed Web of Science ®Google Scholar
• Tang WH, Zhuang XJ, Shu RM, et al. The prevalence of erectile dysfunction among subjects with late-onset hypogonadism: a population-based study in China. Int J Clin Exp Med. 2015;8:13901–13910.
   PubMed Web of Science ®Google Scholar
• Corona G, Rastrelli G, Forti G, et al. Update in testosterone therapy for men. J Sex Med. 2011;8:639–654. quiz 655.
   PubMed Web of Science ®Google Scholar
• Ahn HS, Park CM, Lee SW. The clinical relevance of sex hormone levels and sexual activity in the ageing male. BJU Int. 2002;89:526–530.
   PubMed Web of Science ®Google Scholar
• Gray A, Feldman HA, McKinlay JB, et al. Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts Male Aging Study. J Clin Endocrinol Metab. 1991;73:1016–1025.
   PubMed Web of Science ®Google Scholar
• Ponholzer A, Plas E, Schatzl G, et al. Relationship between testosterone serum levels and lifestyle in aging men. Aging Male. 2005;8:190–193.
   PubMedGoogle Scholar
• Müezzinoğu T, Gümüş B, Temeltaş G, et al. A relationship of sex hormone levels and erectile dysfunction: which tests should be done routinely? Yonsei Med J. 2007;48:1015–1019.
   PubMed Web of Science ®Google Scholar
• Heinemann LAJ, Zimmermann T, Vermuelen A, et al. new aging males’ symptoms (AMS) rating scale. Aging Male. 1999;2:105–114.
   Google Scholar
• Rosen RC, Cappelleri JC, Smith MD, et al. Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res. 1999;11:319–326.
   PubMed Web of Science ®Google Scholar
• Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab. 1999;84:3666–3672.
   PubMed Web of Science ®Google Scholar
• Li JH, Yu XH, Zheng JB, et al. The reproductive health indices and sex hormone levels in middle-aged and elderly Chinese men. Aging Male. 2016; 19:143–147.
   PubMed Web of Science ®Google Scholar
• Ichioka K, Nishiyama H, Yoshimura K, et al. Aging Males' Symptoms scale in Japanese men attending a multiphasic health screening clinic. Urology. 2006;67:589–593.
   PubMed Web of Science ®Google Scholar
• Liu Z, Liu J, Shi X, et al. Comparing calculated free testosterone with total testosterone for screening and diagnosing late-onset hypogonadism in aged males: a cross-sectional study. J Clin Lab Anal. 2016. Forthcoming. doi: 10.1002/jcla.22073.
   Web of Science ®Google Scholar
• Antonio L, Wu FC, O'Neill TW, et al. Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone. J Clin Endocrinol Metab. 2016;101:2647–2657.
   PubMed Web of Science ®Google Scholar
• Karabakan M, Keskin E, Akdemir S, et al. Effect of tadalafil 5 mg daily treatment on the ejaculatory times, lower urinary tract symptoms and erectile function in patients with erectile dysfunction. Int Braz J Urol. 2017;43:317–324.
   PubMed Web of Science ®Google Scholar
• Pexman-Fieth C, Behre HM, Morales A, et al. A 6-month observational study of energy, sexual desire, and body proportions in hypogonadal men treated with a testosterone 1% gel. Aging Male. 2014; 17:1–11.
   PubMed Web of Science ®Google Scholar
• Jain P, Rademaker AW, McVary KT. Testosterone supplementation for erectile dysfunction: results of a meta-analysis. J Urol. 2000;164:371–375.
   PubMed Web of Science ®Google Scholar
• Chen W, Liu ZY, Wang LH, et al. Are the Aging Male's Symptoms (AMS) scale and the Androgen Deficiency in the Aging Male (ADAM) questionnaire suitable for the screening of late-onset hypogonadism in aging Chinese men? Aging Male. 2013;16:92–96.
   PubMed Web of Science ®Google Scholar
• Kratzik CW, Schatzl G, Lunglmayr G, et al. The impact of age, body mass index and testosterone on erectile dysfunction. J Urol. 2005;174:240–243.
   PubMed Web of Science ®Google Scholar
• Tajar A, Forti G, O'Neill TW, et al. Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study. J Clin Endocrinol Metab. 2010;95:1810–1818.
   PubMed Web of Science ®Google Scholar
• Mercer CH, Tanton C, Prah P, et al. Changes in sexual attitudes and lifestyles in Britain through the life course and over time: findings from the National Surveys of Sexual Attitudes and Lifestyles (Natsal). Lancet. 2013;382:1781–1794.
   PubMed Web of Science ®Google Scholar
• Dean J, Shechter A, Vertkin A, et al. Sexual Health and Overall Wellness (SHOW) survey in men and women in selected European and Middle Eastern countries. J Int Med Res. 2013;41:482–492.
   PubMed Web of Science ®Google Scholar
• García-Cruz E, Leibar-Tamayo A, Romero-Otero J, et al. Marked testosterone deficiency-related symptoms may be associated to higher metabolic risk in men with low testosterone levels. J Sex Med. 2014;11:2292–2301.
   PubMed Web of Science ®Google Scholar
• Hamanoue N, Tanabe M, Tanaka T, et al. A higher score on the Aging Males’ Symptoms scale is associated with insulin resistance in middle-aged men. Endocr J. 2017;64:521–530.
   PubMed Web of Science ®Google Scholar
• Derby CA, Mohr BA, Goldstein I, et al. Modifiable risk factors and erectile dysfunction: can lifestyle changes modify risk? Urology. 2000;56:302.
   PubMed Web of Science ®Google Scholar
• Yassin AA, Nettleship JE, Salman M, et al. Waist circumference is superior to weight and BMI in predicting sexual symptoms, voiding symptoms and psychosomatic symptoms in men with hypogonadism and erectile dysfunction. Andrologia. 2017;49:e12634.
   PubMed Web of Science ®Google Scholar
• Almehmadi Y, Yassin DJ, Yassin AA. Erectile dysfunction is a prognostic indicator of comorbidities in men with late onset hypogonadism. Aging Male. 2015;18:186–194.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Tolrà J, Torremadé Barreda J, del Rio L, et al. Effects of testosterone treatment on body composition in males with testosterone deficiency syndrome. Aging Male. 2013;16:184–190.
   PubMed Web of Science ®Google Scholar
• Corona G, Rastrelli G, Morgentaler A, et al. Meta-analysis of results of testosterone therapy on sexual function based on International Index of Erectile Function Scores. Eur Urol. 2017. Forthcoming. doi:10.1016/j.eururo.2017.03.032
   Google Scholar
• Pastuszak AW, Moon YM, Scovell J, et al. Poor sleep quality predicts hypogonadal symptoms and sexual dysfunction in male nonstandard shift workers. Urology. 2017;102:121–125.
   PubMed Web of Science ®Google Scholar
• Min SK, Choi K, Kim SK, et al. Phosphorus as predictive factor for erectile dysfunction in middle aged men: a cross sectional study in Korea. Investig Clin Urol. 2016;57:442–448.
   PubMed Web of Science ®Google Scholar