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Original Paper

Biochemical characterization of terbinafine-resistant Trichophytonrubrum isolates

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Pages 525-529 | Received 08 Sep 2003, Accepted 16 Dec 2003, Published online: 09 Jul 2009

References

  • Ryder NS. Terbinafine: mode of action and properties of the squalene epoxidase inhibition. Br J Dermatol 1992; 126\Suppl. 39: 2–7.
  • Ryder NS, Frank I, Dupont MC. Ergosterol biosynthesis inhibi-tion by the thiocarbamate antifungal agents tolnaftate and tolciclate. Ant imicrob Agents Chemother 1986; 29: 858–860.
  • Ryder NS, Mieth H. Allylamine antifungal drugs. Curr Top Med Mycol 1992; 4: 158–188.
  • Mukherjee PK, Leidich SD, Isham I, Leitner I, Ryder NS, Ghannoum MA. Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine. Ant imicrob Agents Chemother 2003; 47: 82–86.
  • Favre B, Ryder NS. Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic agents. Ant imicrob Agents Chemother 1996; 40: 443–447.
  • Ryder NS. Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent. Antimicrob Agents Chemother 1985; 27: 252–256.
  • Favre B, Didmon M, Ryder NS. Multiple amino acid substitu-tions in lanosterol 14a-demethylase contribute to azole resistance in Candida albicans. Microbiology 1999; 145: 2715–2725.
  • Balkis MM, Leidich SD, Mukheljee PK, Ghannoum MA. Mechanisms of fungal resistance: an overview Drugs 2002; 62: 1025–1040.
  • Sanglard D, Ischer F, Monod M, Bille J. Cloning of Candida albicans genes conferring resistance to azole antifungal agents:characterization of CDR2, a new multidrug ABC trans-porter gene. Microbiology 1997; 143: 405–416.
  • Polak A. Preclinical data and mode of action of amorolfine. Dermatology 1992; 184\Suppl. 1: 3–7.
  • Bradley MC, Leidich S, Isham N, Elewski BE, Ghannoum MA. Antifungal susceptibilities and genetic relatedness of serial Trichophyton rubrum isolates from patients with onychomycosis of the toenail. Mycoses 1999; 42\Suppl. 2: 105–110.
  • Fernandez-Torres B, Carrillo AJ, Martin E, et al. In vitro activities of 10 antifungal drugs against 508 dermatophyte strains. Ant imicrob Agents Chemother 2001; 45: 2524–2528.
  • Jandrositz A, Turnowsky F, Hogenauer G. The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization. Gene 1991; 107: 155–160.
  • Favre B, Ryder NS. Cloning and expression of squalene epoxidase from the pathogenic yeast Candida albicans. Gene 1997; 189: 119–126.
  • Klobucnikova V, Kohut P, Leber R, et al. Terbinafine resistance in a pleiotropic yeast mutant is caused by a single point mutation in the ERG1 gene. Biochem Biophys Res Comm 2003; 309: 666–671.

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