Manipulating immunity against Aspergillus fumigatus

References

• Latge JP. Aspergillus fumigatus and aspergillosis. Clin Microbiol Rev 1999; 12: 310–350
   PubMed Web of Science ®Google Scholar
• Marr KA, Patterson T, Denning D. Aspergillosis. Pathogenesis, clinical manifestations, and therapy. Infect Dis Clin North Am 2002; 16: 875–894
   PubMed Web of Science ®Google Scholar
• Garlanda C, Hirsch E, Bozza S, et al. Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response. Nature 2002; 420: 182–186
   PubMed Web of Science ®Google Scholar
• McCormack FX, Whitsett JA. The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung. J Clin Invest 2002; 109: 707–712
   PubMed Web of Science ®Google Scholar
• Madan T, Kaur S, Saxena S, et al. Role of collectins in innate immunity against aspergillosis. Med Mycol 2005; 43: 155–163
   Web of Science ®Google Scholar
• Phadke AP, Mehrad B. Cytokines in host defense against Aspergillus: recent advances. Med Mycol 2005; 43: 173–186
   Web of Science ®Google Scholar
• Cenci E, Mencacci A, Casagrande A, et al. Impaired antifungal effector activity but not inflammatory cell recruitment in interleukin-6-deficient mice with invasive pulmonary aspergillosis. J Infect Dis 2001; 184: 610–617
   PubMed Web of Science ®Google Scholar
• Mencacci A, Cenci E, Bacci A, et al. Cytokines in candidiasis and aspergillosis. Curr Pharm Biotechnol 2000; 1: 235–251
   PubMedGoogle Scholar
• Walsh TJ, Roilides E, Cortez K, et al. Control, immunoregulation, and expression of innate pulmonary host defenses against Aspergillus fumigatus. Med Mycol 2005; 43: 165–172
   Web of Science ®Google Scholar
• Sabroe I, Read RC, Whyte MK, et al. Toll-like receptors in health and disease: complex questions remain. J Immunol 2003; 171: 1630–1635
   PubMed Web of Science ®Google Scholar
• Bellocchio S, Montagnoli C, Bozza S, et al. The contribution of the toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo. J Immunol 2004; 172: 3059–3069
   PubMed Web of Science ®Google Scholar
• Roeder A, Kirschning CJ, Rupec RA, Schaller M, Korting HC. Toll-like receptors and innate antifungal responses. Trends Microbiol 2004; 12: 44–49
   PubMed Web of Science ®Google Scholar
• Netea MG, Warris A, Van der Meer JW, et al. Aspergillus fumigatus evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transduction. J Infect Dis 2003; 188: 320–326
   PubMed Web of Science ®Google Scholar
• Wang JE, Warris A, Ellingsen EA, et al. Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infect Immun 2001; 69: 2402–2406
   PubMed Web of Science ®Google Scholar
• Mambula SS, Sau K, Henneke P, Golenbock DT, Levitz SM. Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus. J Biol Chem 2002; 277: 39320–39326
   PubMed Web of Science ®Google Scholar
• Bellocchio S, Moretti S, Perruccio K, et al. TLRs govern neutrophil activity in aspergillosis. J Immunol 2004; 173: 7406–7415
   PubMed Web of Science ®Google Scholar
• Grazziutti M, Przepiorka D, Rex JH, et al. Dendritic cell-mediated stimulation of the in vitro lymphocyte response to Aspergillus. Bone Marrow Transplant 2001; 27: 647–652
   PubMed Web of Science ®Google Scholar
• Bozza S, Gaziano R, Spreca A, et al. Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus. J Immunol 2002; 168: 1362–1371
   PubMed Web of Science ®Google Scholar
• Bozza S, Perruccio K, Montagnoli C, et al. A dendritic cell vaccine against invasive aspergillosis in allogeneic hematopoietic transplantation. Blood 2003; 102: 3807–3814
   PubMed Web of Science ®Google Scholar
• Bozza S, Montagnoli C, Gaziano R, et al. Dendritic cell-based vaccination against opportunistic fungi. Vaccine 2004; 22: 857–864
   PubMed Web of Science ®Google Scholar
• Serrano-Gomez D, Dominguez-Soto A, Ancochea J, et al. Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin mediates binding and internalization of Aspergillus fumigatus conidia by dendritic cells and macrophages. J Immunol 2004; 173: 5635–5643
   PubMed Web of Science ®Google Scholar
• Romani L. Immunity to fungal infections. Nat Rev Immunol 2004; 4: 1–23
   PubMed Web of Science ®Google Scholar
• Bozza S, Gaziano R, Lipford GB, et al. Vaccination of mice against invasive aspergillosis with recombinant Aspergillus proteins and CpG oligodeoxynucleotides as adjuvants. Microbes Infect 2002; 4: 1281–1290
   PubMed Web of Science ®Google Scholar
• Reddy V, Iturraspe JA, Tzolas AC, et al. Low dendritic cell count after allogeneic hematopoietic stem cell transplantation predicts relapse, death, and acute graft-versus-host disease. Blood 2004; 103: 4330–4335
   PubMed Web of Science ®Google Scholar
• Fagnoni FF, Oliviero B, Giorgiani G, et al. Reconstitution dynamics of plasmacytoid and myeloid dendritic cell precursors after allogeneic myeloablative hematopoietic stem cell transplantation. Blood 2004; 104: 281–289
   PubMed Web of Science ®Google Scholar
• Perruccio K, Bozza S, Montagnoli C, et al. Prospects for dendritic cell vaccination against fungal infections in hematopoietic transplantation. Blood Cells Mol Dis 2004; 33: 248–255
   PubMed Web of Science ®Google Scholar
• Marr KA, Carter RA, Boeckh M, Martin P, Corey L. Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors. Blood 2002; 100: 4358–4366
   PubMed Web of Science ®Google Scholar
• Denning DW, Follansbee SE, Scolaro M, et al. Pulmonary aspergillosis in the acquired immunodeficiency syndrome. N Engl J Med 1991; 324: 654–662
   PubMed Web of Science ®Google Scholar
• Roilides E, Katsifa H, Walsh TJ. Pulmonary host defences against Aspergillus fumigatus. Res Immunol 1998; 149: 454–465
   PubMedGoogle Scholar
• Hebart H, Bollinger C, Fisch P, et al. Analysis of T-cell responses to Aspergillus fumigatus antigens in healthy individuals and patients with hematologic malignancies. Blood 2002; 100: 4521–4528
   PubMed Web of Science ®Google Scholar
• Cenci E, Mencacci A, Fe d'Ostiani C, et al. Cytokine- and T helper-dependent lung mucosal immunity in mice with invasive pulmonary aspergillosis. J Infect Dis 1998; 178: 1750–1760
   PubMed Web of Science ®Google Scholar
• Cenci E, Mencacci A, Bacci A, et al. T cell vaccination in mice with invasive pulmonary aspergillosis. J Immunol 2000; 165: 381–388
   PubMed Web of Science ®Google Scholar
• Kurup VP. Immunology of allergic bronchopulmonary aspergillosis. Indian J Chest Dis Allied Sci 2000; 42: 225–237
   PubMedGoogle Scholar
• Akbari O, DeKruyff RH, Umetsu DT. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat Immunol 2001; 2: 725–731
   PubMed Web of Science ®Google Scholar
• Mills KH. Regulatory T cells: friend or foe in immunity to infection?. Nat Rev Immunol 2004; 4: 841–855
   PubMed Web of Science ®Google Scholar
• O'Garra A, Vieira P. Regulatory T cells and mechanisms of immune system control. Nat Med 2004; 10: 801–805
   PubMed Web of Science ®Google Scholar
• Belkaid Y, Rouse BT. Natural regulatory T cells in infectious disease. Nat Immunol 2005; 6: 353–360
   PubMed Web of Science ®Google Scholar
• Ostroukhova M, Seguin-Devaux C, Oriss TB, et al. Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3. J Clin Invest 2004; 114: 28–38
   PubMed Web of Science ®Google Scholar
• Sakaguchi S. Naturally arising Foxp3-expressing CD25 + CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005; 6: 345–352
   PubMed Web of Science ®Google Scholar
• von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immunol 2005; 6: 338–344
   PubMed Web of Science ®Google Scholar
• Alyanakian MA, You S, Damotte D, et al. Diversity of regulatory CD4 + T cells controlling distinct organ-specific autoimmune diseases. Proc Natl Acad Sci USA 2003; 100: 15806–15811
   PubMed Web of Science ®Google Scholar
• Ermann J, Hoffmann P, Edinger M, et al. Only the CD62L+ subpopulation of CD4 + CD25+ regulatory T cells protects from lethal acute GVHD. Blood 2005; 105: 2220–2226
   PubMed Web of Science ®Google Scholar
• Maloy KJ, Salaun L, Cahill R, et al. CD4 + CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med 2003; 197: 111–119
   PubMed Web of Science ®Google Scholar
• Fallarino F, Grohmann U, Hwang KW, et al. Modulation of tryptophan catabolism by regulatory T cells. Nat Immunol 2003; 4: 1206–1212
   PubMed Web of Science ®Google Scholar
• Bozza S, Fallarino F, Pitzurra L, et al. A crucial role for tryptophan catabolism at the host/Candida albicans interface. J Immunol 2005; 174: 2910–2918
   PubMed Web of Science ®Google Scholar
• Roilides E, Dimitriadou A, Kadiltsoglou I, et al. IL-10 exerts suppressive and enhancing effects on antifungal activity of mononuclear phagocytes against Aspergillus fumigatus. J Immunol 1997; 158: 322–329
   PubMed Web of Science ®Google Scholar
• Montagnoli C, Fallarino F, Gaziano R, et al. Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism. J Immunol 2006; 176: 1712–1723
   PubMed Web of Science ®Google Scholar
• Banerjee B, Kelly KJ, Fink JN, et al. Modulation of airway inflammation by immunostimulatory CpG oligodeoxynucleotides in a murine model of allergic aspergillosis. Infect Immun 2004; 72: 6087–6094
   PubMed Web of Science ®Google Scholar
• Hayashi T, Beck L, Rossetto C, et al. Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J Clin Invest 2004; 114: 270–279
   PubMed Web of Science ®Google Scholar
• von Bubnoff D, Fimmers R, Bogdanow M, et al. Asymptomatic atopy is associated with increased indoleamine 2,3-dioxygenase activity and interleukin-10 production during seasonal allergen exposure. Clin Exp Allergy 2004; 34: 1056–1063
   PubMed Web of Science ®Google Scholar
• Roilides E, Sein T, Roden M, Schaufele RL, Walsh TJ. Elevated serum concentrations of interleukin-10 in nonneutropenic patients with invasive aspergillosis. J Infect Dis 2001; 183: 518–520
   PubMed Web of Science ®Google Scholar
• Segal BH, Kwon-Chung J, Walsh TJ, et al. Immunotherapy for fungal infections. Clin Infect Dis 2006; 42: 507–515
   PubMed Web of Science ®Google Scholar