2,895
Views
10
CrossRef citations to date
0
Altmetric
Infectious Disease

Cost-effectiveness analysis of implementing an antimicrobial stewardship program in critical care units

, , , , , & show all
Pages 652-659 | Received 13 Dec 2016, Accepted 14 Mar 2017, Published online: 13 Apr 2017

References

  • Woodford N, Livermore DM. Infections caused by Gram-positive bacteria: a review of the global challenge. J Infect 2009;59:S4-S16
  • Hecker MT, Aron DC, Patel NP, et al. Unnecessary use of antimicrobials in hospitalized patients: current patterns of misuse with an emphasis on the antianaerobic spectrum of activity. Arch Intern Med 2003;163:972-8
  • Willemsen I, Groenhuijzen A, Bogaers D, et al. Appropriateness of antimicrobial therapy measured by repeatedprevalence surveys, Antimicrob Agents Chemother 2007;51:864-7
  • The bacterial challenge: time to react. A call to narrow the gap between multidrug-resistant bacteria in the EU and the development of new antibacterial agents. Stockholm: European Centre for Disease Prevention and Control; 2009. http://ecdc.europa.eu/en/publications/. Accessed March 2015
  • Dellinger RP, Levy MM, Rhodes A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 2013;39:165-228
  • Paruk F, Richards G, Scribante J, et al. Antibiotic prescription practices and their relationship to outcome in South Africa: findings of the prevalence of infection in South African intensive care units (PISA) study. S Afr Med J 2012;102:613-6
  • Dellit TH, Owens RC, McGowan JE Jr, et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 2007;44:159-77
  • Brusselaers N, Vogelaers D, Blot S. The rising problem of antimicrobial resistance in the intensive care unit. Ann Intensive Care 2011;1:47
  • Grau S, Bou G, Fondevilla E, et al. How to measure and monitor antimicrobial consumption and resistance. Enfermedades Infecc Microbiol Clínica 2013;31:S16-24
  • Davey P, Brown E, Charani E, et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev 2013;4:CD003543
  • Allerberger F, Lechner A, Wechsler-Fördös A, et al. Optimization of antibiotic use in hospitals—antimicrobial stewardship and the EU project ABS international. Chemotherapy 2008;54:260-7
  • Santana-Cabrera L, Lorenzo-Torrent R, Sánchez-Palacios M, et al. [Analysis of stay and mortality in an intensive care unit]. Rev Calid Asist 2014;29:121-3
  • Colmenero M. [El ritual de la falta de camas]. Med Intensiva 2011; 35:139-42
  • Kaki R, Elligsen M, Walker S, et al. Impact of antimicrobial stewardship in critical care: a systematic review. J Antimicrob Chemother 2011;66:1223-30
  • Feazel LM, Malhotra A, Perencevich EN, et al. Effect of antibiotic stewardship programmes on Clostridium difficile incidence: a systematic review and meta-analysis. J Antimicrob Chemother 2014;69:1748-54
  • Bouza E, Rodríguez-Créixems M, Alcalá L, et al. Is Clostridium difficile infection an increasingly common severe disease in adult intensive care units? A 10-year experience. J Crit Care 2015;30:543-9
  • Azkárate I, Sebastián R, Cabarcos E, et al. [Registro observacional y prospectivo de sepsis grave/shock séptico en un hospital terciario de la provincia de Guipúzcoa]. Med Intensiva 2012;36:250-6
  • Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESCIM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250-6
  • Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias (GTEIS-SEMICYUC). [Estudio Nacional de Vigilancia de Infección Nosocomial en UCI (ENVIN-HELICS)]. 2013. Retrieved from http://hws.vhebron.net/envin-helics. Accessed April 2015
  • Ma X, Xie J, Yang Y, et al. Antimicrobial stewardship of Chinese ministry of health reduces multidrug-resistant organism isolates in critically ill patients: a pre-post study from a single center. BMC Infect Dis 2016;16:704
  • López-Pueyo MJ, Barcenilla-Gaite F, Amaya-Villar R, et al. [Multirresistencia antibiótica en unidades de críticos]. Med Intensiva 2011;35:41-53
  • Cosgrove SE. The relationship between antimicrobial resistance and patient outcomes: mortality, length of hospital stay, and health care costs. Clin Infect Dis 2006;42:S82-S9
  • Pop-Vicas A, Opal SM. The clinical impact of multidrug-resistant gram-negative bacilli in the management of septic shock. Virulence 2014;5:206-12
  • Peto Z, Benko R, Matuz M, et al. Results of a local antibiotic management program on antibiotic use in a tertiary intensive care unir in Hungary. Infection 2008;36:560-4
  • López Bastida J, Oliva J, Antoñanzas F, et al. [Propuesta de guía para la evaluación económica aplicada a las tecnologías sanitarias]. Gac Sanit 2010;24:154-70
  • Rebert C. [Estudio epidemiológicode la infección nosocomial en el Servicio de UCI del Hospital Universitario de Canarias]. Thesis doctoral. Universidad de la Laguna; 2005
  • Lindemark F, Haaland A, Kvåle R, et al. Age, risk, and life expectancy in Norwegian intensive care: a registry-based population modelling study. PLoS One 2015;10:e0125907
  • Brinkman S, de Jonge E, Abu-Hanna A, et al. Mortality after hospital discharge in ICU patients. Crit Care Med 2013;41:1229-36
  • Meyer E, Schwab F, Gastmeier P, et al. Surveillance of antimicrobial use and antimicrobial resistance in German intensive care units (SARI): a summary of the data from 2001 through 2004. Infection 2006;34:303-9
  • Micek ST, Ward S, Fraser VJ, et al. A randomized controlled trial of an antibiotic discontinuation policy for clinically suspected ventilator-associated pneumonia. Chest 2004;125:1791-9
  • Scheetz M, Bolon MK, Postelnick M, et al. Cost-effectiveness analysis of an antimicrobial stewardship team on bloodstream infections: a probabilistic analysis. J Antimicrobial Chemother 2009;63:816-25
  • Hong LT, Goolsby TA, Sherman DS, et al. Continuous infusion vs intermittent vancomycin in neurosurgical intensive care unit patien. J Crit Care 2015;30:1153.e1-6
  • Bao H, Lv Y, Wang D, et al. Clinical outcomes of extended versus intermittent administration of piperacillin/tazobactam for the treatment of hospital-acquired pneumonia: a randomized controlled trial. Eur J Clin Microbiol Infect Dis 2017;36:459-66
  • Roberts RR, Hota B, Ahmad I, et al. Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: implications for antibiotic stewardship. Clin Infect Dis 2009;49:1175-84
  • Dik J-WH, Vemer P, Friedrich AW, et al. Financial evaluations of antibiotic stewardship programs-a systematic review. Front Microbiol 2015;6:317
  • Lautenbach E, Weiner MG, Nachamkin I, et al. Imipenem resistance among pseudomonas aeruginosa isolates: risk factors for infection and impact of resistance on clinical and economic outcomes. Infect Control Hosp Epidemiol 2006;27:893-900
  • Karanika S, Paudel S, Grigoras C, et al. Clinical and economic outcomes from the implementation of hospital based antimicrobial stewardship programs: a systematic review and meta-analysis. Antimicrob Agents Chemother. 2016;60:4840-52
  • Asensio Á, Bouza E, Grau S, et al. [Cost of Clostridium difficile associated diarrhea in Spain]. Rev Esp Salud Pública 2013;87:25-33
  • Generalitat Valenciana. [Retribuciones del personal sanitario 2015]. 2016. Retrived from: http://www.san.gva.es/web/dgrhs/retribuciones-personal-iiss. Accessed on May 2016
  • Bantar C, Sartori B, Vesco E, et al. A hospital wide intervention program to optimize the quality of antibiotic use: impact on prescribing practice, antibiotic consumption, cost savings, and bacterial resistance. Clin Infect Dis 2003;37:180-6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.