Prevalence and impact of antipsychotic discontinuation among commercially-insured patients with bipolar disorder

References

• Hirschfeld RM, Bowden CL, Gitlin MJ, et al. Treatment of patients with bipolar disorder. APA Practice Guidelines 2002. 2010.
   Google Scholar
• Miller S, Dell’Osso B, Ketter TA. The prevalence and burden of bipolar depression. J Affect Disord. 2014;169 Suppl 1:S3–S11. doi: 10.1016/S0165-0327(14)70003-5.
   PubMed Web of Science ®Google Scholar
• Sylvia LG, Montana RE, Deckersbach T, et al. Poor quality of life and functioning in bipolar disorder. Int J Bipolar Disord. 2017;5(1):10. doi: 10.1186/s40345-017-0078-4.
   PubMedGoogle Scholar
• Dilsaver SC. An estimate of the minimum economic burden of bipolar I and II disorders in the United States: 2009. J Affect Disord. 2011;129(1–3):79–83. doi: 10.1016/j.jad.2010.08.030.
   PubMed Web of Science ®Google Scholar
• Bessonova L, Ogden K, Doane MJ, et al. The economic burden of bipolar disorder in the United States: a systematic literature review. Clinicoecon Outcomes Res. 2020;12:481–497. doi: 10.2147/CEOR.S259338.
   PubMed Web of Science ®Google Scholar
• Harvard Medical School. National Comorbidity Survey (NCS). [cited 2017 Aug 21]. Available from: https://www.hcp.med.harvard.edu/ncs/index.php.
   Google Scholar
• Azorin JM, Perret LC, Fakra E, et al. Alcohol use and bipolar disorders: risk factors associated with their co-occurrence and sequence of onsets. Drug Alcohol Depend. 2017;179:205–212. doi: 10.1016/j.drugalcdep.2017.07.005.
   PubMed Web of Science ®Google Scholar
• McIntyre RS, Berk M, Brietzke E, et al. Bipolar disorders. Lancet. 2020;396(10265):1841–1856. doi: 10.1016/S0140-6736(20)31544-0.
   PubMed Web of Science ®Google Scholar
• McIntyre RS, Danilewitz M, Liauw SS, et al. Bipolar disorder and metabolic syndrome: an international perspective. J Affect Disord. 2010;126(3):366–387. doi: 10.1016/j.jad.2010.04.012.
   PubMed Web of Science ®Google Scholar
• Jauhar S, Young AH. Controversies in bipolar disorder; role of second-generation antipsychotic for maintenance therapy. Int J Bipolar Disord. 2019;7(1):10. doi: 10.1186/s40345-019-0145-0.
   PubMedGoogle Scholar
• Gitlin M, Frye MA. Maintenance therapies in bipolar disorders. Bipolar Disord. 2012;14:51–65. doi: 10.1111/j.1399-5618.2012.00992.x.
   PubMed Web of Science ®Google Scholar
• Bauer M, Glenn T, Alda M, et al. Trajectories of adherence to mood stabilizers in patients with bipolar disorder. Int J Bipolar Disord. 2019;7(1):19. doi: 10.1186/s40345-019-0154-z.
   PubMed Web of Science ®Google Scholar
• Chakrabarti S. Treatment-adherence in bipolar disorder: a patient-centred approach. WJP. 2016;6(4):399–409. doi: 10.5498/wjp.v6.i4.399.
   Google Scholar
• Lingam R, Scott J. Treatment non-adherence in affective disorders. Acta Psychiatr Scand. 2002;105(3):164–172. doi: 10.1034/j.1600-0447.2002.1r084.x.
   PubMed Web of Science ®Google Scholar
• Jawad I, Watson S, Haddad PM, et al. Medication nonadherence in bipolar disorder: a narrative review. Ther Adv Psychopharmacol. 2018;8(12):349–363. doi: 10.1177/2045125318804364.
   PubMed Web of Science ®Google Scholar
• Garcia S, Martinez-Cengotitabengoa M, Lopez-Zurbano S, et al. Adherence to antipsychotic medication in bipolar disorder and schizophrenic patients: a systematic review. J Clin Psychopharmacol. 2016;36(4):355–371. doi: 10.1097/JCP.0000000000000523.
   PubMed Web of Science ®Google Scholar
• Gianfrancesco FD, Sajatovic M, Rajagopalan K, et al. Antipsychotic treatment adherence and associated mental health care use among individuals with bipolar disorder. Clin Ther. 2008;30(7):1358–1374. doi: 10.1016/s0149-2918(08)80062-8.
   PubMed Web of Science ®Google Scholar
• Broder MS, Greene M, Chang E, et al. Atypical antipsychotic adherence is associated with lower inpatient utilization and cost in bipolar I disorder. J Med Econ. 2019;22(1):63–70. doi: 10.1080/13696998.2018.1543188.
   PubMed Web of Science ®Google Scholar
• Mago R, Borra D, Mahajan R. Role of adverse effects in medication nonadherence in bipolar disorder. Harv Rev Psychiatry. 2014;22(6):363–366. doi: 10.1097/HRP.0000000000000017.
   PubMed Web of Science ®Google Scholar
• Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45(6):613–619. doi: 10.1016/0895-4356(92)90133-8.
   PubMed Web of Science ®Google Scholar
• Muench J, Hamer AM. Adverse effects of antipsychotic medications. Am Fam Physician. 2010;81(5):617–622.
   PubMed Web of Science ®Google Scholar
• Patel KR, Cherian J, Gohil K, et al. Schizophrenia: overview and treatment options. P T. 2014;39(9):638–645.
   PubMedGoogle Scholar
• Weiss C, Weiller E, Baker RA, et al. The effects of brexpiprazole and aripiprazole on body weight as monotherapy in patients with schizophrenia and as adjunctive treatment in patients with major depressive disorder: an analysis of short-term and long-term studies. Int Clin Psychopharmacol. 2018;33(5):255–260. doi: 10.1097/YIC.0000000000000226.
   PubMed Web of Science ®Google Scholar
• Campbell RH, Diduch M, Gardner KN, et al. Review of cariprazine in management of psychiatric illness. Ment Health Clin. 2017;7(5):221–229. doi: 10.9740/mhc.2017.09.221.
   PubMedGoogle Scholar
• Khandker R, Chekani F, Limone B, et al. Cardiometabolic outcomes among schizophrenia patients using antipsychotics: the impact of high weight gain risk vs low weight gain risk treatment. BMC Psychiatry. 2022;22(1):133. doi: 10.1186/s12888-022-03746-0.
   PubMed Web of Science ®Google Scholar
• Semahegn A, Torpey K, Manu A, et al. Psychotropic medication non-adherence and its associated factors among patients with major psychiatric disorders: a systematic review and meta-analysis. Syst Rev. 2020;9(1):1–18. doi: 10.1186/s13643-020-1274-3.
   PubMed Web of Science ®Google Scholar
• Gentile S. Discontinuation rates during long-term, second-generation antipsychotic long-acting injection treatment: a systematic review. Psychiatry Clin Neurosci. 2019;73(5):216–230. doi: 10.1111/pcn.12824.
   PubMed Web of Science ®Google Scholar
• Gerding LB, Labbate LA, Measom MO, et al. Alcohol dependence and hospitalization in schizophrenia. Schizophr Res. 1999;38(1):71–75. doi: 10.1016/s0920-9964(98)00177-7.
   PubMed Web of Science ®Google Scholar
• Grenard JL, Munjas BA, Adams JL, et al. Depression and medication adherence in the treatment of chronic diseases in the United States: a meta-analysis. J Gen Intern Med. 2011;26(10):1175–1182. doi: 10.1007/s11606-011-1704-y.
   PubMed Web of Science ®Google Scholar
• Torrent C, Amann B, Sánchez-Moreno J, et al. Weight gain in bipolar disorder: pharmacological treatment as a contributing factor. Acta Psychiatr Scand. 2008;118(1):4–18. doi: 10.1111/j.1600-0447.2008.01204.x.
   PubMed Web of Science ®Google Scholar