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Hematology

Healthcare costs among hemophilia A patients in the United States treated with rurioctocog alfa pegol (FVIII-PEG) or antihemophilic factor (recombinant), FC fusion protein (rFVIIIFc) using real-world data

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Pages 1278-1286 | Received 30 May 2023, Accepted 29 Sep 2023, Published online: 25 Oct 2023

References

  • Centers for Disease Control and Prevention. Data and Statistics on Hemophilia; 2022. Available from: https://www.cdc.gov/ncbddd/hemophilia/data.html
  • National Organization for Rare Disorders. Hemophilia A. Rare Disease Database; Updated 2021. Available from https://rarediseases.org/rare-diseases/hemophilia-a/
  • Salen P, Babiker HM, Hemophilia A. StatPearls. Treasure Island (FL): StatPearls Publishing LLC; 2022.
  • Soucie JM, Evatt B, Jackson D. Occurrence of hemophilia in the United States. The hemophilia surveillance system project investigators. Am J Hematol. 1998;59(4):288–294. doi: 10.1002/(SICI)1096-8652(199812)59:4<288::AID-AJH4>3.0.CO;2-I.
  • Soucie JM, Miller CH, Dupervil B, et al. Occurrence rates of haemophilia among males in the United States based on surveillance conducted in specialized haemophilia treatment centres. Haemophilia. 2020;26(3):487–493. doi: 10.1111/hae.13998.
  • Srivastava A, Santagostino E, Dougall A, et al. WFH guidelines for the management of hemophilia, 3rd edition. Haemophilia. 2020;26(Suppl 6):1–158. doi: 10.1111/hae.14046.
  • Chen SL. Economic costs of hemophilia and the impact of prophylactic treatment on patient management. Am J Manage Care. 2016;22(5):S126–S133.
  • Aledort L, Mannucci PM, Schramm W, et al. Factor VIII replacement is still the standard of care in haemophilia A. Blood Transfus. 2019;17(6):479–486.
  • Croteau SE, Cheng D, Cohen AJ, et al. Regional variation and cost implications of prescribed extended half-life factor concentrates among U.S. Haemophilia Treatment Centres for patients with moderate and severe haemophilia. Haemophilia. 2019;25(4):668–675. doi: 10.1111/hae.13758.
  • Malec LM, Cheng D, Witmer CM, et al. The impact of extended half-life factor concentrates on prophylaxis for severe hemophilia in the United States. Am J Hematol. 2020;95(8):960–965. doi: 10.1002/ajh.25844.
  • U.S. Food and Drug Administration. Antihemophilic factor (recombinant), PEGylated (Adynovate) prescibing infomation. 2022. Available from: https://www.fda.gov/media/102389/download
  • U.S. Food and Drug Administration. Antihemophilic factor (recombinant), Fc fusion protein (Eloctate) prescibing information. 2022. Available from: https://www.fda.gov/media/88746/download
  • Zhou ZY, Koerper MA, Johnson KA, et al. Burden of illness: direct and indirect costs among persons with hemophilia a in the United States. J Med Econ. 2015;18(6):457–465. doi: 10.3111/13696998.2015.1016228.
  • Croteau SE, Cook K, Sheikh L, et al. Health care resource utilization and costs among adult patients with hemophilia A on factor VIII prophylaxis: an administrative claims analysis. J Manag Care Spec Pharm. 2021;27(3):316–326. doi: 10.18553/jmcp.2021.27.3.316.
  • Shrestha A, Eldar-Lissai A, Hou N, et al. Real-world resource use and costs of haemophilia A-related bleeding. Haemophilia. 2017;23(4):e267–e275. doi: 10.1111/hae.13220.
  • Recht M, He C, Chen E, et al. Resource utilization and treatment costs of patients with severe hemophilia A: real-world data from the ATHNdataset. eJHaem. 2022;3(2):341–352. doi: 10.1002/jha2.412.
  • Thornburg CD, Adamski K, Cook K, et al. Health care costs and resource utilization among commercially insured adult patients with hemophilia A managed with FVIII prophylaxis in the United States. J Manag Care Spec Pharm. 2022;28(4):449–460. doi: 10.18553/jmcp.2021.21368.
  • Carcao MD, Chelle P, Clarke E, et al. Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: is there a difference? J Thromb Haemost. 2019;17(7):1085–1096. doi: 10.1111/jth.14469.
  • Teitel J, Sholzberg M, Iorio A. Extended half-life factor VIII concentrates in adults with hemophilia A: comparative pharmacokinetics of two products. Res Pract Thromb Haemost. 2021;5(2):349–355. doi: 10.1002/rth2.12476.
  • Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45(6):613–619. doi: 10.1016/0895-4356(92)90133-8.
  • U.S. Bureau of Labor Statistics. Consumer price index—all urban consumers, US medical care 2020. 2020. Available from: https://www.bls.gov/cpi/data.htm
  • AMCP. Summit on hemophilia: findings from the AMCP Market Insights Program. 2018. Available from: https://www.amcp.org/Resource-Center/meeting-proceedings-findings/amcp-market-insights-summit-hemophilia