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Research Article

Examining heterogeneity in depression symptoms and associations with cognition and everyday function in MCI

, ORCID Icon, , , & ORCID Icon
Pages 185-194 | Received 15 Mar 2022, Accepted 11 Jul 2022, Published online: 21 Jul 2022

References

  • Avlund, K., Rantanen, T., & Schroll, M. (2007). Factors underlying tiredness in older adults. Aging Clinical and Experimental Research, 19(1), 16–25. https://doi.org/10.1007/BF03325206
  • Bakk, Z., & Vermunt, J. K. (2016). Robustness of stepwise latent class modeling with continuous distal outcomes. Structural Equation Modeling: A Multidisciplinary Journal, 23(1), 20–31. https://doi.org/10.1080/10705511.2014.955104
  • Barbour, K. A., & Blumenthal, J. A. (2005). Exercise training and depression in older adults. Neurobiology of Aging, 26(1), 119–123. https://doi.org/10.1016/j.neurobiolaging.2005.09.007
  • Baune, B. T., Suslow, T., Arolt, V., & Berger, K. (2007). The relationship between psychological dimensions of depressive symptoms and cognitive functioning in the elderly – The MEMO-Study. Journal of Psychiatric Research, 41(3–4), 247–254. https://doi.org/10.1016/j.jpsychires.2006.06.004
  • Benjamini, Y. & Hochberg, Y. (1995). Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society: Series B (Methodological), 57(1), 289–300. https://doi.org/10.1111/j.2517-6161.1995.tb02031.x
  • Bennett, S., & Thomas, A. J. (2014). Depression and dementia: Cause, consequence or coincidence? Maturitas, 79(2), 184–190. https://doi.org/10.1016/j.maturitas.2014.05.009
  • Bentler, P. M. (1990). Comparative fit indexes in structural models. Psychological Bulletin, 107(2), 238–246. https://doi.org/10.1037/0033-2909.107.2.238
  • Bernstein, J. P., Calamia, M. & Keller, J. N. (2018). Multiple self-reported sleep measures are differentially associated with cognitive performance in community-dwelling nondemented elderly. Neuropsychology, 32(2), 220–229. https://doi.org/10.1037/neu0000407
  • Brailean, A., Aartsen, M. J., Muniz-Terrera, G., Prince, M., Prina, A. M., Comijs, H. C., Huisman, M., & Beekman, A. (2017). Longitudinal associations between late-life depression dimensions and cognitive functioning: A cross-domain latent growth curve analysis. Psychological Medicine, 47(4), 690–702. https://doi.org/10.1017/S003329171600297X
  • Brommelhoff, J. A., Gatz, M., Johansson, B., McArdle, J. J., Fratiglioni, L., & Pedersen, N. L. (2009). Depression as a risk factor or prodromal feature for dementia? Findings in a population-based sample of Swedish twins. Psychology and Aging, 24(2), 373–384. https://doi.org/10.1037/a0015713
  • Butters, M. A., Becker, J. T., Nebes, R. D., Zmuda, M. D., Mulsant, B. H., Pollock, B. G., & Reynolds, C. F., III. (2000). Changes in cognitive functioning following treatment of late-life depression. American Journal of Psychiatry, 157(12), 1949–1954. https://doi.org/10.1176/appi.ajp.157.12.1949
  • Butters, M. A., Young, J. B., Lopez, O., Aizenstein, H. J., Mulsant, B. H., Reynolds, C. F., III, DeKosky, S. T., & Becker, J. T. (2022). Pathways linking late-life depression to persistent cognitive impairment and dementia. Dialogues in Clinical Neuroscience, 10(3), 345–357. https://doi.org/10.31887/DCNS.2008.10.3/mabutters
  • Byers, A. L., & Yaffe, K. (2011). Depression and risk of developing dementia. Nature Reviews Neurology, 7(6), 323–331. https://doi.org/10.1038/nrneurol.2011.60
  • Cuthbert, B. N., & Insel, T. R. (2013). Toward the future of psychiatric diagnosis: The seven pillars of RDoC. BMC Medicine, 11(1), 1–8. https://doi.org/10.1186/1741-7015-11-126
  • Dehn, L. B., Driessen, M., & Beblo, T. (2020). Patients with major depression show greater memory improvement if motivation is increased: An exploratory study under real-life-like conditions. Journal of Clinical and Experimental Neuropsychology, 42(3), 307–318. https://doi.org/10.1080/13803395.2020.1711874
  • Dotson, V. M., Szymkowicz, S. M., Kirton, J. W., McLaren, M. E., Green, M. L., & Rohani, J. Y. (2014). Unique and interactive effect of anxiety and depressive symptoms on cognitive and brain function in young and older adults. Journal of Depression & Anxiety, S1(1), 3. https://doi.org/10.4172/2167-1044.S1-003
  • Dotson, V. M., Taiwo, Z., Minto, L. R., Bogoian, H. R., & Gradone, A. M. (2021). Orbitofrontal and cingulate thickness asymmetry associated with depressive symptom dimensions. Cognitive, Affective, & Behavioral Neuroscience, 21(6), 1297–1305. https://doi.org/10.3758/s13415-021-00923-8
  • Etters, L., Goodall, D., & Harrison, B. E. (2008). Caregiver burden among dementia patient caregivers: A review of the literature. Journal of the American Academy of Nurse Practitioners, 20(8), 423–428. https://doi.org/10.1111/j.1745-7599.2008.00342.x
  • Farias, S. T., Chou, E., Harvey, D. J., Mungas, D., Reed, B., DeCarli, C., Park, L. Q., & Beckett, L. (2013). Longitudinal trajectories of everyday function by diagnostic status. Psychology and Aging, 28(4), 1070–1075. https://doi.org/10.1037/a0034069
  • Floyd, F. J. & Widaman, K. F. (1995). Factor analysis in the development and refinement of clinical assessment instruments. Psychological Assessment, 7(3), 286–299. https://doi.org/10.1037/1040-3590.7.3.286
  • Gallo, J. J., Anthony, J. C., & Muthén, B. O. (1994). Age differences in the symptoms of depression: A latent trait analysis. Journal of Gerontology, 49(6), P251–P264. https://doi.org/10.1093/geronj/49.6.P251
  • Gold, D. A. (2012). An examination of instrumental activities of daily living assessment in older adults and mild cognitive impairment. Journal of Clinical and Experimental Neuropsychology, 34(1), 11–34. https://doi.org/10.1080/13803395.2011.614598
  • Hall, C, A, and Reynolds-III, C, F. (2014). Late-life depression in the primary care setting: Challenges, collaborative care, and prevention. Maturitas, 79(2), 147–152. https://doi.org/10.1016/j.maturitas.2014.05.026
  • Hayden, K. M., Jones, R. N., Zimmer, C., Plassman, B. L., Browndyke, J. N., Pieper, C., Warren, L. H., & Welsh-Bohmer, K. A. (2011). Factor structure of the National Alzheimer’s Coordinating Centers uniform dataset neuro- psychological battery: An evaluation of invariance between and within groups over time. Alzheimer Disease and Associated Disorders, 25(2), 128–137. https://doi.org/10.1097/WAD.0b013e3181ffa76d
  • Hegeman, J. M., De Waal, M. W. M., Comijs, H. C., Kok, R. M., & Van der Mast, R. C. (2015). Depression in later life: A more somatic presentation? Journal of Affective Disorders, 170, 196–202. https://doi.org/10.1016/j.jad.2014.08.032
  • Houde, M., Bergman, H., Whitehead, V. & Chertkow, H. (2008). A predictive depression pattern in mild cognitive impairment. International Journal of Geriatric Psychiatry: A journal of the psychiatry of late life and allied sciences, 23(10), 1028–1033. https://doi.org/10.1002/gps.2028
  • Hu, L, & Bentler, P, M. (1999). Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives. Structural Equation Modeling: A Multidisciplinary Journal, 6(1), 1–55. https://doi.org/10.1080/10705519909540118
  • Hybels, C. F., Blazer, D. G., Pieper, C. F., Landerman, L. R., & Steffens, D. C. (2009). Profiles of depressive symptoms in older adults diagnosed with major depression: Latent cluster analysis. The American Journal of Geriatric Psychiatry, 17(5), 387–396. https://doi.org/10.1097/JGP.0b013e31819431ff
  • Hybels, C. F., Blazer, D. G., Landerman, L. R., & Steffens, D. C. (2011). Heterogeneity in symptom profiles among older adults diagnosed with major depression. International Psychogeriatrics, 23(6), 906–922. https://doi.org/10.1017/S1041610210002346
  • Invernizzi, S., Loureiro, I. S., Arachchige, K. G. K., & Lefebvre, L. (2021). Late-life depression, cognitive impairment, and relationship with Alzheimer’s disease. Dementia and Geriatric Cognitive Disorders, 50(5), 1–11. https://doi.org/10.1159/000519453
  • Johnson, L. A., Mauer, C., Jahn, D., Song, M., Wyshywaniuk, L., Hall, J. R., … O’Bryant, S. E. (2013). Cognitive differences among depressed and non‐depressed MCI participants: A project FRONTIER study. International Journal of Geriatric Psychiatry, 28(4), 377–382. https://doi.org/10.1002/gps.3835
  • Jorm, A. F. (2001). History of depression as a risk factor for dementia: An updated review. Australian & New Zealand Journal of Psychiatry, 35(6), 776–781. https://doi.org/10.1046/j.1440-1614.2001.00967.x
  • Köhler, S., van Boxtel, M. P., van Os, J., Thomas, A. J., O’Brien, J. T., Jolles, J., Verhey, F. R., & Allardyce, J. (2010). Depressive symptoms and cognitive decline in community-dwelling older adults. Journal of the American Geriatrics Society, 58(5), 873–879. https://doi.org/10.1111/j.1532-5415.2010.02807.x
  • Korten, N. C., Penninx, B. W., Kok, R. M., Stek, M. L., Oude Voshaar, R. C., Deeg, D. J. & Comijs, H. C. (2014). Heterogeneity of late-life depression: relationship with cognitive functioning. International psychogeriatrics, 26(6), 953–963. https://doi.org/10.1017/S1041610214000155
  • Lourida, I., Soni, M., Thompson-Coon, J., Purandare, N., Lang, I. A., Ukoumunne, O. C., & Llewellyn, D. J. (2013). Mediterranean diet, cognitive function, and dementia: A systematic review. Epidemiology, 24(4), 479–489. https://doi.org/10.1097/EDE.0b013e3182944410
  • Lubke, G. & Muthén, B. O. (2007). Performance of factor mixture models as a function of model size, covariate effects, and class-specific parameters. Structural Equation Modeling: A Multidisciplinary Journal, 14(1), 26–47. https://doi.org/10.1080/10705510709336735
  • MacCallum, R. C., Browne, M. W. & Sugawara, H. M. (1996). Power analysis and determination of sample size for covariance structure modeling. Psychological Methods, 1(2), 130–149. https://doi.org/10.1037/1082-989X.1.2.130
  • Mackin, R. S., Insel, P., Aisen, P. S., Geda, Y. E., & Weiner, M. W., & Alzheimer’s Disease Neuroimaging Initiative. (2012). Longitudinal stability of subsyndromal symptoms of depression in individuals with mild cognitive impairment: Relationship to conversion to dementia after 3 years. International Journal of Geriatric Psychiatry, 27(4), 355–363. https://doi.org/10.1002/gps.2713
  • Martyr, A., Nelis, S. M., & Clare, L. (2014). Predictors of perceived functional ability in early‐stage dementia: Self‐ratings, informant ratings and discrepancy scores. International Journal of Geriatric Psychiatry, 29(8), 852–862. https://doi.org/10.1002/gps.4071
  • McIntyre, R. S., Woldeyohannes, H. O., Soczynska, J. K., Maruschak, N. A., Wium-Andersen, I. K., Vinberg, M., Cha, D. S., Lee, Y., Xiao, H. X., Gallaugher, L. A., Dale, R. M., Alsuwaidan, M. T., Mansur, R. B., Muzina, D. J., Carvalho, A. F., Jerrell, J. M., & Kennedy, S. H. (2016). Anhedonia and cognitive function in adults with MDD: Results from the international mood disorders collaborative project. CNS Spectrums, 21(5), 362–366. https://doi.org/10.1017/S1092852915000747
  • Mehta, K. M., Yaffe, K., & Covinsky, K. E. (2002). Cognitive impairment, depressive symptoms, and functional decline in older people. Journal of the American Geriatrics Society, 50(6), 1045–1050. https://doi.org/10.1046/j.1532-5415.2002.50259.x
  • Mitchell, J., Mathews, H. F., & Yesavage, J. A. (1993). A multidimensional examination of depression among the elderly. Research on Aging, 15(2), 198–219. https://doi.org/10.1177/0164027593152004
  • Mun, E. Y., von Eye, A., Bates, M. E., & Vaschillo, E. G. (2008). Finding groups using model-based cluster analysis: Heterogeneous emotional self-regulatory processes and heavy alcohol use risk. Developmental Psychology, 44(2), 481–495. https://doi.org/10.1037/0012-1649.44.2.481
  • Muthén, L. K. & Muthén, B. O. (2017). Mplus user’s guide. (4th ed.). Los Angeles, CA: Muthén & Muthén.
  • Nguyen, H. T., & Zonderman, A. B. (2006). Relationship between age and aspects of depression: Consistency and reliability across two longitudinal studies. Psychology and Aging, 21(1), 119–126. https://doi.org/10.1037/0882-7974.21.1.119
  • O’Bryant, S. E., Hall, J. R., Cukrowicz, K. C., Edwards, M., Johnson, L. A., Lefforge, D., Jenkins, M., & Dentino, A. (2011). The differential impact of depressive symptom clusters on cognition in a rural multi-ethnic cohort: A Project FRONTIER study. International Journal of Geriatric Psychiatry, 26(2), 199–205. https://doi.org/10.1002/gps.2514
  • Panza, F., Frisardi, V., Capurso, C., D’Introno, A., Colacicco, A. M., Imbimbo, B. P., Santamato, A., Vendemiale, G., Seripa, D., Pilotto, A., Capurso, A., & Solfrizzi, V. (2010). Late-life depression, mild cognitive impairment, and dementia: Possible continuum? The American Journal of Geriatric Psychiatry, 18(2), 98–116. https://doi.org/10.1097/JGP.0b013e3181b0fa13
  • Penninkilampi, R., Casey, A. N., Singh, M. F., & Brodaty, H. (2018). The association between social engagement, loneliness, and risk of dementia: A systematic review and meta- analysis. Journal of Alzheimer’s Disease, 66(4), 1619–1633. https://doi.org/10.3233/JAD-180439
  • Pfeffer, R. I., Kurosaki, T. T., Harrah, C. H., Jr, Chance, J. M., & Filos, S. (1982). Measurement of functional activities in older adults in the community. Journal of Gerontology, 37(3), 323–329. https://doi.org/10.1093/geronj/37.3.323
  • Roberts, R., & Knopman, D. S. (2013). Classification and epidemiology of MCI. Clinics in Geriatric Medicine, 29(4), 753–772. https://doi.org/10.1016/j.cger.2013.07.003
  • Sarkisian, C. A., Hays, R. D., & Mangione, C. M. (2002). Do older adults expect to age successfully? The association between expectations regarding aging and beliefs regarding healthcare seeking among older adults. Journal of the American Geriatrics Society, 50(11), 1837–1843. https://doi.org/10.1046/j.1532-5415.2002.50513.x
  • Sexton, C. E., McDermott, L., Kalu, U. G., Herrmann, L. L., Bradley, K. M., Allan, C. L., Le Masurier, M., Mackay, C. E., & Ebmeier, K. P. (2012). Exploring the pattern and neural correlates of neuropsychological impairment in late-life depression. Psychological Medicine, 42(6), 1195–1202. https://doi.org/10.1017/S0033291711002352
  • Sharifian, N., Gu, Y., Manly, J. J., Schupf, N., Mayeux, R., Brickman, A. M., & Zahodne, L. B. (2020). Linking depressive symptoms and cognitive functioning: The mediating role of leisure activity. Neuropsychology, 34(1), 107–115. https://doi.org/10.1037/neu0000595
  • Sheikh, J. I., & Yesavage, J. A. (1986). Geriatric depression scale (GDS): Recent evidence and development of a shorter version. Clinical Gerontologist: The Journal of Aging and Mental Health, 5(1–2), 165–173. https://doi.org/10.1300/J018v05n01_09
  • Snyder, H. R. (2013). Major depressive disorder is associated with broad impairments on neuropsychological measures of executive function: A meta-analysis and review. Psychological Bulletin, 139(1), 81–132. https://doi.org/10.1037/a0028727
  • Sofi, F., Valecchi, D., Bacci, D., Abbate, R., Gensini, G. F., Casini, A., & Macchi, C. (2011). Physical activity and risk of cognitive decline: A meta-analysis of prospective studies. Journal of Internal Medicine, 269(1), 107–117. https://doi.org/10.1111/j.1365-2796.2010.02281.x
  • Soleimani, L., Ravona-Springer, R., Lin, H. M., Liu, X., Sano, M., Heymann, A., & Beeri, M. S. (2021). Specific dimensions of depression have different associations with cognitive decline in older adults with type 2 diabetes. Diabetes Care, 44(3), 655–662. https://doi.org/10.2337/dc20-2031
  • Tillmann, J., Uljarevic, M., Crawley, D., Dumas, G., Loth, E., Murphy, D., Buitelaar, J., & Charman, T., & AIMS-2-TRIALS LEAP group. (2020). Dissecting the phenotypic heterogeneity in sensory features in autism spectrum disorder: A factor mixture modelling approach. Molecular Autism, 11(1), 67. https://doi.org/10.1186/s13229-020-00367-w
  • Turner, A. D., Capuano, A. W., Wilson, R. S., & Barnes, L. L. (2015). Depressive symptoms and cognitive decline in older African Americans: Two scales and their factors. The American Journal of Geriatric Psychiatry, 23(6), 568–578. https://doi.org/10.1016/j.jagp.2014.08.003
  • Weintraub, S., Salmon, D., Mercaldo, N., Ferris, S., Graff-Radford, N. R., Chui, H., Cummings, J., DeCarli, C., Foster, N. L., Galasko, D., Peskind, E., Dietrich, W., Beekly, D. L., Kukull, W. A., & Morris, J. C. (2009). The Alzheimer’s Disease Centers’ Uniform Data Set (UDS): The neuropsychologic test battery. Alzheimer Disease and Associated Disorders, 23(2), 91–101. https://doi.org/10.1097/WAD.0b013e318191c7dd
  • Weintraub, S., Besser, L., Dodge, H. H., Teylan, M., Ferris, S., Goldstein, F. C., Giordani, B., Kramer, J., Loewenstein, D., Marson, D., Mungas, D., Salmon, D., Welsh-Bohmer, K., Zhou, X.-H., Shirk, S. D., Atri, A., Kukull, W. A., Phelps, C., & Morris, J. C. (2018). Version 3 of the Alzheimer Disease Centers’ neuropsychological test battery in the Uniform data set (UDS). Alzheimer Disease and Associated Disorders, 32(1), 10. https://doi.org/10.1097/WAD.0000000000000223
  • Weisenbach, S. L., Boore, L. A., & Kales, H. C. (2012). Depression and cognitive impairment in older adults. Current Psychiatry Reports, 14(4), 280–288. https://doi.org/10.1007/s11920-012-0278-7
  • Wimo, A., Guerchet, M., Ali, G. C., Wu, Y. T., Prina, A. M., Winblad, B., … Prince, M. (2017). The worldwide costs of dementia 2015 and comparisons with 2010. Alzheimer’s & Dementia, 13(1), 1–7. https://doi.org/10.1016/j.jalz.2016.07.150
  • Woody, M. L., & Gibb, B. E. (2015). Integrating NIMH research domain criteria (RDoC) into depression research. Current Opinion in Psychology, 4, 6–12. https://doi.org/10.1016/j.copsyc.2015.01.004
  • Zahodne, L. B., Stem, Y., & Manly, J. J. (2014). Depressive symptoms precede memory decline, but not vice versa, in non-demented older adults. Journal of the American Geriatrics Society, 62(1), 130–134. https://doi.org/10.1111/jgs.12600

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