Novel learning ratio from the NAB list learning test distinguishes between clinical groups: clinical validation and sex-related differences

References 

• ADNI3. (2016). Alzheimer’s Disease Neuroimaging Initiative: ADNI3 Procedures Manual. Retrieved July 2021 from https://adni.loni.usc.edu/wp-content/uploads/2012/10/ADNI3-Procedures-Manual_v3.0_20170627.pdf
   Google Scholar
• Benedict, R. (1997). Brief Visuospatial Memory Test-Revised. Psychological Assessment Resources.
   Google Scholar
• Benton, A., Hamsher, D., & Sivan, A. (1994). Multilingual Aphasia Examination. Psychological Assessment Resources, Inc.
   Google Scholar
• Brandt, J., & Benedict, R. (1997). Hopkins verbal learning test-revised. Psychological Assessment Resources, Inc.
   Google Scholar
• Brunet, H. E., Caldwell, J. Z. K., Brandt, J., & Miller, J. B. (2020). Influence of sex differences in interpreting learning and memory within a clinical sample of older adults. Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition, 27(1), 18–39. https://doi.org/10.1080/13825585.2019.1566433
   PubMed Web of Science ®Google Scholar
• de Frias, C. M., Nilsson, L. G., & Herlitz, A. (2006). Sex differences in cognition are stable over a 10-year period in adulthood and old age. Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition, 13(3–4), 574–587. https://doi.org/10.1080/13825580600678418
   PubMed Web of Science ®Google Scholar
• Estevez-Gonzalez, A., Kulisevsky, J., Boltes, A., Otermin, P., & Garcia-Sanchez, C. (2003). Rey verbal learning test is a useful tool for differential diagnosis in the preclinical phase of Alzheimer’s disease: Comparison with mild cognitive impairment and normal aging. International Journal of Geriatric Psychiatry, 18(11), 1021–1028. https://doi.org/10.1002/gps.1010
   PubMed Web of Science ®Google Scholar
• Fox, M., Berzuini, C., & Knapp, L. A. (2013). Cumulative estrogen exposure, number of menstrual cycles, and Alzheimer’s risk in a cohort of British women. Psychoneuroendocrinology, 38(12), 2973–2982. https://doi.org/10.1016/j.psyneuen.2013.08.005
   PubMed Web of Science ®Google Scholar
• Gavett, B. E., Poon, S. J., Ozonoff, A., Jefferson, A. L., Nair, A. K., Green, R. C., & Stern, R. A. (2009). Diagnostic utility of the NAB List Learning test in Alzheimer’s disease and amnestic mild cognitive impairment. Journal of the International Neuropsychological Society: JINS, 15(1), 121–129. https://doi.org/10.1017/S1355617708090176
   PubMed Web of Science ®Google Scholar
• Gifford, K. A., Phillips, J. S., Samuels, L. R., Lane, E. M., Bell, S. P., Liu, D., Alzheimer’s disease neuroimaging, I., & Hohman, T. J. (2015). Associations between verbal learning slope and neuroimaging markers across the cognitive aging spectrum. Journal of the International Neuropsychological Society: JINS, 21(6), 455–467. https://doi.org/10.1017/S1355617715000430
   PubMed Web of Science ®Google Scholar
• Gilsanz, P., Lee, C., Corrada, M. M., Kawas, C. H., Quesenberry, C. P., Jr, & Whitmer, R. A. (2019). Reproductive period and risk of dementia in a diverse cohort of health care members. Neurology, 92(17), e2005–e2014. https://doi.org/10.1212/WNL.0000000000007326
   PubMed Web of Science ®Google Scholar
• Hammers, D. B. (2023a). The relationship between learning slopes and alzheimer’s disease biomarkers in cognitively intact participants with and without subjective memory complaints. Journal of Clinical and Experimental Neuropsychology.
   Web of Science ®Google Scholar
• Hammers, D. B. 2023b. Alzheimer’s & Dementia. The Journal of the Alzheimer’s Association Learning Slopes in Early Learning Slopes in EarlyOnset Alzheimer’s Disease
   Google Scholar
• Hammers, D. B., Gradwohl, B. D., Kucera, A., Abildskov, T. J., Wilde, E. A., & Spencer, R. J. (2021). Preliminary validation of the learning ratio for the HVLT-R and BVMT-R in older adults. Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology, 34(3), 170–181. https://doi.org/10.1097/wnn.0000000000000277
   PubMed Web of Science ®Google Scholar
• Hammers, D. B., Spencer, R. J., & Apostolova, L. G. (2022a). Validation of and demographically adjusted normative data for the learning ratio derived from the RAVLT in robustly intact older adults. Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists, 37(5), 981–993. https://doi.org/10.1093/arclin/acac002
   PubMed Web of Science ®Google Scholar
• Hammers, D. B., Suhrie, K., Dixon, A., Gradwohl, B. D., Archibald, Z. G., King, J. B., Spencer, R. J., Duff, K., & Hoffman, J. M. (2022b). Relationship between a novel learning slope metric and Alzheimer’s disease biomarkers. Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition, 29(5), 799–819. https://doi.org/10.1080/13825585.2021.1919984
   PubMed Web of Science ®Google Scholar
• Hammers, D. B., Suhrie, K., Dixon, A., Gradwohl, B. D., Duff, K., & Spencer, R. J. (2022). Validation of HVLT-R, BVMT-R, and RBANS Learning Slope Scores along the Alzheimer’s Continuum. Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists, 37(1), 78–90. https://doi.org/10.1093/arclin/acab023
   PubMed Web of Science ®Google Scholar
• Hammers, D. B., Suhrie, K. R., Porter, S. M., Dixon, A. M., & Duff, K. (2022). Validation of one-year reliable change in the RBANS for community-dwelling older adults with amnestic mild cognitive impairment. The Clinical Neuropsychologist, 36(6), 1304–1327. https://doi.org/10.1080/13854046.2020.1807058
   PubMed Web of Science ®Google Scholar
• Hirnstein, M., Stuebs, J., Moe, A., & Hausmann, M. (2023). Sex/gender differences in verbal fluency and verbal-episodic memory: A meta-analysis. Perspectives on Psychological Science: a Journal of the Association for Psychological Science, 18(1), 67–90. https://doi.org/10.1177/17456916221082116
   PubMedGoogle Scholar
• Hosmer, D., Lemeshow, S., & Sturdivant, R. (2013). Applied Logistic Regression (Third) ed.). John Wiley & Sons, INC.
   Google Scholar
• James, G. A., Kearney-Ramos, T. E., Young, J. A., Kilts, C. D., Gess, J. L., & Fausett, J. S. (2016). Functional Independence in resting-state connectivity facilitates higher-order cognition. Brain and Cognition, 105, 78–87. https://doi.org/10.1016/j.bandc.2016.03.008
   PubMed Web of Science ®Google Scholar
• Lague-Beauvais, M., Brunet, J., Gagnon, L., Lesage, F., & Bherer, L. (2013). A fNIRS investigation of switching and inhibition during the modified Stroop task in younger and older adults. Neuroimage, 64, 485–495. https://doi.org/10.1016/j.neuroimage.2012.09.042
   PubMed Web of Science ®Google Scholar
• Lesher, E. L., & Berryhill, J. S. (1994). Validation of the geriatric depression scale-short form among inpatients. Journal of Clinical Psychology, 50(2), 256–260. https://doi.org/10.1002/1097-4679(199403)50:2<256::AID-JCLP2270500218>3.0.CO;2-E
   PubMed Web of Science ®Google Scholar
• Malpetti, M., Ballarini, T., Presotto, L., Garibotto, V., Tettamanti, M., & Perani, D. (2017). Gender differences in healthy aging and Alzheimer’s Dementia: A 18 F-FDG-PET study of brain and cognitive reserve. Human Brain Mapping, 38(8), 4212–4227. https://doi.org/10.1002/hbm.23659
   PubMed Web of Science ®Google Scholar
• Mast, B. T., & Allaire, J. C. (2006). Verbal learning and everyday functioning in dementia: An application of latent variable growth curve modeling. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 61(3), 167–173. https://doi.org/10.1093/geronb/61.3.p167
   PubMed Web of Science ®Google Scholar
• Maxwell, K. M. & McGuinness, B. (2018). 120Demographics and diagnoses of new patients seen at memory clinic: How appropriate are referrals? Age and Ageing, 47(suppl_5), v1–v12. https://doi.org/10.1093/ageing/afy141.14
   Google Scholar
• McCarrey, A. C., An, Y., Kitner-Triolo, M. H., Ferrucci, L., & Resnick, S. M. (2016). Sex differences in cognitive trajectories in clinically normal older adults. Psychology and Aging, 31(2), 166–175. https://doi.org/10.1037/pag0000070
   PubMed Web of Science ®Google Scholar
• Moradi, E., Hallikainen, I., Hanninen, T., & Tohka, J. (2017). Rey’s Auditory Verbal Learning Test scores can be predicted from whole brain MRI in Alzheimer’s disease. NeuroImage: Clinical, 13, 415–427. https://doi.org/10.1016/j.nicl.2016.12.011
   PubMed Web of Science ®Google Scholar
• Moulin, C. J., James, N., Freeman, J. E., & Jones, R. W. (2004). Deficient acquisition and consolidation: Intertrial free recall performance in Alzheimer’s disease and mild cognitive impairment. Journal of Clinical and Experimental Neuropsychology, 26(1), 1–10. https://doi.org/10.1076/jcen.26.1.1.23940
   PubMed Web of Science ®Google Scholar
• Mueller, A. E., Segal, D. L., Gavett, B., Marty, M. A., Yochim, B., June, A., & Coolidge, F. L. (2015). Geriatric Anxiety Scale: Item response theory analysis, differential item functioning, and creation of a ten-item short form (GAS-10). International Psychogeriatrics, 27(7), 1099–1111. https://doi.org/10.1016/j.psyneuen.2013.08.005
   PubMed Web of Science ®Google Scholar
• Muller, L. D., Guhn, A., Zeller, J. B., Biehl, S. C., Dresler, T., Hahn, T., Fallgatter, A. J., Polak, T., Deckert, J., & Herrmann, M. J. (2014). Neural correlates of a standardized version of the trail making test in young and elderly adults: A functional near-infrared spectroscopy study. Neuropsychologia, 56, 271–279. https://doi.org/10.1016/j.neuropsychologia.2014.01.019
   PubMed Web of Science ®Google Scholar
• Petersen, R. C. (2004). Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine, 256(3), 183–194. https://doi.org/10.1111/j.1365-2796.2004.01388.x
   PubMed Web of Science ®Google Scholar
• Rabin, L. A., Pare, N., Saykin, A. J., Brown, M. J., Wishart, H. A., Flashman, L. A., & Santulli, R. B. (2009). Differential memory test sensitivity for diagnosing amnestic mild cognitive impairment and predicting conversion to alzheimer’s disease. Aging, Neuropsychology, and Cognition, 16(3), 357–376. https://doi.org/10.1080/13825580902825220
   PubMed Web of Science ®Google Scholar
• Randolph, C. (2012). Repeatable battery for the assessment of neuropsychological status. The Psychological Corporation.
   Google Scholar
• Reitan, R. (1992). Trail making test: manual for administration and scoring.
   Google Scholar
• Reynolds, C. K. R. (2017). Reynolds Interference Task. Psychological Assessment Resources, Inc.
   Google Scholar
• Royall, D. R., Cordes, J. A., & Polk, M. (1998). CLOX: An executive clock drawing task. Journal of Neurology, Neurosurgery & Psychiatry, 64(5), 588–594. https://doi.org/10.1136/jnnp.64.5.588
   PubMed Web of Science ®Google Scholar
• Rye, I., Vik, A., Kocinski, M., Lundervold, A. S., & Lundervold, A. J. (2022). Predicting conversion to Alzheimer’s disease in individuals with Mild Cognitive Impairment using clinically transferable features. Scientific Reports, 12(1), 15566. https://doi.org/10.1038/s41598-022-18805-5
   PubMed Web of Science ®Google Scholar
• Sattler, J. R. J. (2009). Assessment with the WAIS-IV.
   Google Scholar
• Schmidt, M. (1996). The Rey Auditory Verbal Learning Test. Western Psychological Services.
   Google Scholar
• Small, G. W. (2006). Diagnostic issues in dementia: Neuroimaging as a surrogate marker of disease. Journal of Geriatric Psychiatry and Neurology, 19(3), 180–185. https://doi.org/10.1177/0891988706291089
   PubMed Web of Science ®Google Scholar
• song, Y., & Hakoda, Y. (2015). An fMRI study of the functional mechanisms of Stroop/reverse-Stroop effects. Behavioural Brain Research, 290, 187–196. https://doi.org/10.1016/j.bbr.2015.04.047
   PubMed Web of Science ®Google Scholar
• Spencer, R. J., Gradwohl, B. D., Williams, T. F., Kordovski, V. M., & Hammers, D. B. (2020). Developing learning slope scores for the repeatable battery for the assessment of neuropsychological status. Applied Neuropsychology. Adult, 1–7. https://doi.org/10.1080/23279095.2020.1791870
   PubMed Web of Science ®Google Scholar
• Stratford, J. A., LoGiudice, D., Flicker, L., Cook, R., Waltrowicz, W., & Ames, D. (2003). A memory clinic at a geriatric hospital: A report on 577 patients assessed with the CAMDEX over 9 years. The Australian and New Zealand Journal of Psychiatry, 37(3), 319–326. https://doi.org/10.1046/j.1440-1614.2003.01174.x
   PubMed Web of Science ®Google Scholar
• Subramaniapillai, S., Almey, A., Natasha Rajah, M., & Einstein, G. (2021). Sex and gender differences in cognitive and brain reserve: Implications for Alzheimer’s disease in women. Frontiers in Neuroendocrinology, 60, 100879. https://doi.org/10.1016/j.yfrne.2020.100879
   PubMed Web of Science ®Google Scholar
• Sundermann, E. E., Maki, P. M., Rubin, L. H., Lipton, R. B., Landau, S., Biegon, A., & Alzheimer’s Disease Neuroimaging, I. (2016). Female advantage in verbal memory: Evidence of sex-specific cognitive reserve. Neurology, 87(18), 1916–1924. https://doi.org/10.1212/WNL.0000000000003288
   PubMed Web of Science ®Google Scholar
• Wang, P., Li, J., Li, H., & Zhang, S. (2013). Differences in learning rates for item and associative memories between amnestic mild cognitive impairment and healthy controls. Behavioral and Brain Functions: BBF, 9(1), 29. https://doi.org/10.1186/1744-9081-9-29
   PubMed Web of Science ®Google Scholar
• Webber, T. A., Marceaux, J. C., Critchfield, E. A., & Soble, J. R. (2019). Relative impacts of mild and major neurocognitive disorder on rate of verbal learning acquisition. Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists, 34(6), 803–808. https://doi.org/10.1093/arclin/acy089
   PubMed Web of Science ®Google Scholar
• Wechsler, D. (2008). Wechsler Adult intelligence scale-fourth edition. Pearson, Inc.
   Google Scholar
• Wechsler, D. (2009). Advanced Clinical Solutions. Pearson, Inc.
   Google Scholar
• White, T. S. R. (2003). Neuropsychological assessment battery. Psychological Assessment Resources, Inc.
   Google Scholar
• Zhang, J., Zhou, W., Wang, L., Zhang, X., & Harvard Aging Brain, S. (2017). Gender differences of neuropsychological profiles in cognitively normal older people without amyloid pathology. Comprehensive Psychiatry, 75, 22–26. https://doi.org/10.1016/j.comppsych.2017.02.00
   PubMed Web of Science ®Google Scholar
• Zhang, J., Zhou, W., Wang, L., Zhang, X., & Harvard Aging Brain, S. (2017). Gender differences of neuropsychological profiles in cognitively normal older people without amyloid pathology. Compr Psychiatry, 75, 22–26. doi:10.1016/j.comppsych.2017.02.00
   PubMed Web of Science ®Google Scholar