Publication Cover
Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 123, 2017 - Issue 2
142
Views
4
CrossRef citations to date
0
Altmetric
Original Article

Date fruits inhibit hepatocyte apoptosis and modulate the expression of hepatocyte growth factor, cytochrome P450 2E1 and heme oxygenase-1 in carbon tetrachloride-induced liver fibrosis

, , , , &
Pages 78-92 | Received 18 May 2016, Accepted 19 Oct 2016, Published online: 14 Dec 2016

References

  • Abdelaziz DH, Ali SA. (2014). The protective effect of Phoenix dactylifera L. seeds against CCl4-induced hepatotoxicity in rats. J Ethnopharmacol, 155:736–43.
  • Ahmed MB, Hasona NA, Selemain AH. (2008). Protective effects of extract from dates (Phoenix dactylifera L.) and ascorbic acid on thioacetamide-induced hepatotoxicity in rats. Iran J Pharm Res, 7:193–201.
  • Al-Farsi M, Alasalvar C, Al-Abid M, et al. (2007). Compositional and functional characteristics of dates, syrups, and their by-products. Food Chem, 104:943–7.
  • Al-Qarawi AA, Mousa HM, Ali BEH, et al. (2004). Protective effect of extracts from dates (Phoenix dactylifera L.) on carbon tetrachloride–induced hepatotoxicity in rats. Int J Appl Res Vet Med, 2:176–80.
  • Al-Qarawi AA, Abdel-Rahman H, Ali BH, et al. (2005). The ameliorative effect of dates (Phoenix dactylifera L.) on ethanol-induced gastric ulcer in rats. J Ethnopharmacol, 98:313–17.
  • Al-Rasheed NM, Attia HA, Mohamad RA, et al. (2015). Aqueous date flesh or pits extract attenuates liver fibrosis via suppression of hepatic stellate cell activation and reduction of inflammatory cytokines, transforming growth factor- β 1 and angiogenic markers in carbon tetrachloride-intoxicated rats. Evid Based Complement Alternat Med, 2015:247357.
  • Amersi F, Buelow R, Kato H, et al. (1999). Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury. J Clin Invest, 104:1631–9.
  • Arauz J, Moreno MG, Cortés-Reynosa P, et al. (2013). Coffee attenuates fibrosis by decreasing the expression of TGF-β and CTGF in a murine model of liver damage. J Appl Toxicol, 33:970–9.
  • Ashino T, Sugiuchi J, Uehara J, et al. (2011). Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-1. J Toxicol Sci, 36:635–43.
  • Barikbin R, Neureiter D, Wirth J, et al. (2012). Induction of heme oxygenase 1 prevents progression of liver fibrosis in Mdr2 knockout mice. Hepatology, 55:553–62.
  • Bataller R, Brenner DA. (2005). Liver fibrosis. J Clin Invest, 115:209–18.
  • Berberat PO, Katori M, Kaczmarek E, et al. (2003). Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury. FESAB J, 17:1724–6.
  • Besbes S, Blecker C, Deroanne C, et al. (2004). Date seeds: Chemical composition and characteristic profiles of the lipid fraction. Food Chem, 84:577–84.
  • Canbay A, Friedman S, Gores GJ. (2004). Apoptosis: The nexus of liver injury and fibrosis. Hepatology, 39:273–8.
  • Canbay A, Higuchi H, Bronk SF, et al. (2002). Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis. Gastroenterology, 123:1323–30.
  • Dong D, Yin L, Qi Y, et al. (2015). Protective effect of the total saponins from rosa laevigata michx fruit against carbon tetrachloride-induced liver fibrosis in rats. Nutrients, 7:4829–50.
  • El Arem A, Saafi EB, Ghrairi F, et al. (2014). Aqueous date fruit extract protects against lipid peroxidation and improves antioxidant status in the liver of rats subchronically exposed to trichloroacetic acid. J Physiol Biochem, 70:451–64.
  • El Bassiouny A, El-Bassiouni N, Nosseir M, et al. (2008). Circulating and hepatic Fas expression in HCV-induced chronic liver disease and hepatocellular carcinoma. Medscape J Med, 10:130.
  • El-Gazzar UB, El-Far AH, Abdel maksoud HA. (2009). The ameliorative effect of phoenix dactylifera extract on CCl4 hepatotoxicity in New Zealand rabbits. J Appl Sci Res, 5:1082–7.
  • Elmore S. (2007). Apoptosis: A review of programmed cell death. Toxicol Pathol, 35:495–516.
  • Elsharkawy AM, Oakley F, Mann DA. (2005). The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis. Apoptosis, 10:927–39.
  • Ferris CD, Jaffrey SR, Sawa A, et al. (1999). Haem oxygenase-1 prevents cell death by regulating cellular iron. Nat Cell Biol, 1:152–7.
  • Ghavami S, Hashemi M, Kadkhoda K, et al. (2005). Apoptosis in liver diseases–detection and therapeutic applications. Med Sci Monit, 11:337–45.
  • Gressner OA, Gressner AM. (2008). Connective tissue growth factor: A fibrogenic master switch in fibrotic liver diseases. Liver Int, 28:1065–79.
  • Guo XL, Liang B, Wang XW, et al. (2013). Glycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in rats via a p53-mediated pathway. World J Gastroenterol, 19:3781–91.
  • Hamad I, AbdElgawad H, Al Jaouni S, et al. (2015). Metabolic analysis of various date palm fruit (Phoenix dactylifera L.) cultivars from Saudi Arabia to assess their nutritional quality. Molecules, 27:13620–41.
  • Jodo S, Kobayashi S, Nakajima Y, et al. (1998). Elevated serum levels of soluble Fas/APO-1 (CD95) in patients with hepatocellular carcinoma. Clin Exp Immunol, 112:166–71.
  • Kang LI, Mars WM, Michalopoulos GK. (2012). Signals and cells involved in regulating liver regeneration. Cells, 1:1261–92.
  • Kuramitsu K, Gallo D, Yoon M, et al. (2011). Carbon monoxide enhances early liver regeneration in mice after hepatectomy. Hepatology, 53:2016–26.
  • Lee TY, Chang HH, Wang GJ, et al. (2006). Water-soluble extract of Salvia miltiorrhiza ameliorates carbon tetrachloride-mediated hepatic apoptosis in rats. J Pharm Pharmacol, 58:659–65.
  • Lee UE, Friedman SL. (2011). Mechanisms of hepatic fibrogenesis. Best Pract Res Clin Gastroenterol, 25:195–206.
  • Li L, Grenard P, Nhieu JT, et al. (2003). Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts. Gastroenterology, 125:460–9.
  • Liang B, Guo XL, Jin J, et al. (2015). Glycyrrhizic acid inhibits apoptosis and fibrosis in carbon-tetrachloride-induced rat liver injury. World J Gastroenterol, 7, 21:5271–80.
  • Lin X, Zhang S, Huang Q, et al. (2012). Protective effect of Fufang-Liu-Yue-Qing, a traditional Chinese herbal formula, on CCl4 induced liver fibrosis in rats. J Ethnopharmacol, 142:548–56.
  • Liu B, Qian JM. (2015). Cytoprotective role of heme oxygenase-1 in liver ischemia reperfusion injury. Int J Clin Exp Med, 8:19867–73.
  • Liu LG, Yan H, Zhang W, et al. (2004). Induction of heme oxygenase-1 in human hepatocytes to protect them from ethanol-induced cytotoxicity. Biomed Environ Sci, 17:315–26.
  • Liu T, Wang X, Karsdal MA, et al. (2012). Molecular serum markers of liver fibrosis. Biomark Insights, 7:105–17.
  • Milbury PE, Graf B, Curran-Celentano JM, Blumberg JB. (2007). Bilberry (Vaccinium myrtillus) anthocyanins modulate heme oxygenase-1 and glutathione S-transferase-pi expression in ARPE-19 cells. Invest Ophthalmol Vis Sci, 48:2343–9.
  • Mori T, Kawara S, Shinozaki M, et al. (1999). Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model. J Cell Physiol, 181:153–9.
  • Mrabet A, Rodríguez-Arcos R, et al. (2012). Dietary fiber from Tunisian common date cultivars (Phoenix dactylifera L.): Chemical composition, functional properties, and antioxidant capacity. J Agric Food Chem, 60:3658–64.
  • Ogaly HA, Eltablawy NA, El-Behairy AM, et al. (2015). Hepatocyte growth factor mediates the antifibrogenic action of ocimum bacilicum essential oil against CCl4-induced liver fibrosis in rats. Molecules, 20:13518–35.
  • Otterbein LE, Soares MP, Yamashita K, Bach FH. (2003). Heme oxygenase-1: Unleashing the protective properties of heme. Trends Immunol, 24:449–55.
  • Ozawa S, Uchiyama K, Nakamori M, et al. (2006). Combination gene therapy of HGF and truncated type II TGF-beta receptor for rat liver cirrhosis after partial hepatectomy. Surgery, 139:563–73.
  • Pelli N, Floreani A, Torre F, et al. (2007). Soluble apoptosis molecules in primary biliary cirrhosis: Analysis and commitment of the Fas and tumour necrosis factor-related apoptosis-inducing ligand systems in comparison with chronic hepatitis C. Clin Exp Immunol, 148:85–9.
  • Sass G, Barikbin R, Tiegs G. (2012). The multiple functions of heme oxygenase-1 in the liver. Z Gastroenterol, 50:34–40.
  • Scapagnini G, Vasto S, Abraham NG, et al. (2011). Modulation of Nrf2/ARE pathway by food polyphenols: A nutritional neuroprotective strategy for cognitive and neurodegenerative disorders. Mol Neurobiol, 44:192–201.
  • Souli A, Sebai H, Rtibi K, et al. (2014). Effects of dates pulp extract and palm sap (Phoenix dactylifera L.) on gastrointestinal transit activity in healthy rats. J Med Food, 17:782–6.
  • Tsui TY, Lau CK, Ma J, et al. (2006). Adeno-associated virus-mediated heme oxygenase-1 gene transfer suppresses the progression of micronodular cirrhosis in rats. World J. Gastroenterol, 12:2016–23.
  • Tsui TY, Lau CK, Ma J, et al. (2005). rAAV-mediated stable expression of heme oxygenase-1 in stellate cells: A new approach to attenuate liver fibrosis in rats. Hepatology, 42:335–42.
  • Tsukada BS, Parsons CJ, Rippe RA. (2006). Mechanisms of liver fibrosis. Clin Chim Acta, 364:33–60.
  • Valva P, Casciato P, Lezama C, et al. (2013). Serum apoptosis markers related to liver damage in chronic hepatitis C: sFas as a marker of advanced fibrosis in children and adults while M30 of severe steatosis only in children. PLoS One, 8:e53519.
  • Vayalil PK. (2002). Antioxidant and antimutagenic properties of aqueous extract of date fruit (Phoenix dactylifera L. Arecaceae). J Agric Food Chem, 50:610–17.
  • Vongsak B, Mangmool S, Gritsanapan W. (2015). Antioxidant activity and induction of mRNA expressions of antioxidant enzymes in HEK-293 cells of moringa oleifera leaf extract. Planta Med, 81:1084–9.
  • Weber LW, Boll M, Stampfl A. (2003). Hepatotoxicity and mechanism of action of haloalkanes: Carbon tetrachloride as a toxicological model. Crit Rev Toxicol, 33:105–36.
  • Weng HL, Ciuclan L, Liu Y, et al. (2007). Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes. Hepatology, 46:1257–70.
  • Xia J, Dai C, Michalopoulos GK, Liu Y. (2006). Hepatocyte growth factor attenuates liver fibrosis induced by bile duct ligation. Am J Pathol, 168:1500–12.
  • Xue H, Guo H, Li YC, Hao ZM. (2007). Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats. World J Gastroenterol, 13:5384–90.
  • Yu JL, Li JH, Chengz RG, et al. (2014). Effect of matrine on transforming growth factor β1 and hepatocyte growth factor in rat liver fibrosis model. Asian Pac J Trop Med, 7:390–3.
  • Zekri AR, Alam El-Din HM, Bahnassy AA, et al. (2010). Serum levels of soluble Fas, soluble tumor necrosis factor-receptor II, interleukin-2 receptor and interleukin-8 as early predictors of hepatocellular carcinoma in Egyptian patients with hepatitis C virus genotype-4. Comp Hepatol, 9:1.
  • Zhang J, Zhou S, Zhou Y, et al. (2014). Hepatocyte growth factor gene-modified adipose-derived mesenchymal stem cells ameliorate radiation induced liver damage in a rat model. PLoS ONE, 9:e114670.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.