References
- Banerjee, S., et al., 2008. Multi-targeted therapy of cancer by genistein. Cancer letters, 269 (2), 226–242.
- Bauvois, B., 2012. New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumorprogression. Biochimica et biophysica acta (bba) - reviews on cancer, 1825, 29–36.
- Braselmann, H., et al., 2015. CFAssay: statistical analysis of the colony formation assay. Radiation oncology, 10, 223.
- Casey, S.C., et al., 2015. Cancer prevention and therapy through the modulation of the tumor microenvironment. Seminars in cancer biology, 35, S199–S223.
- Choi, E.J., Jung, J.Y., and Kim, G.H., 2014. Genistein inhibits the proliferation and differentiation of MCF-7 and 3T3-L1 cells via the regulation of ERalpha expression and induction of apoptosis. Experimental and therapeutic medicine, 8 (2), 454–458.
- Chou, R.H., et al., 2013. Fisetin inhibits migration and invasion of human cervical cancer cells by down-regulating urokinase plasminogen activator expression through suppressing the p38 MAPK-dependent NF-kappaB signaling pathway. Plos one, 8 (8), e71983.
- Cuadrado, A., and Nebreda, A.R., 2010. Mechanisms and functions of p38 MAPK signalling. Biochemical journal, 429 (3), 403–417.
- Cui, S., et al., 2017. Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways. Oncotarget, 8, 21674–21691.
- Elmore, S., 2007. Apoptosis: a review of programmed cell death. Toxicologic pathology, 35 (4), 495–516.
- Gregoraszczuk, E.L., et al., 2015. Effect of chemotherapeutic drugs on caspase-3 activity, as a key biomarker for apoptosis in ovarian tumor cell cultured as monolayer. A pilot study. Iranian journal of pharmaceutical research, 14 (4), 1153–1161.
- Hsu, A., et al., 2010. Differential effects of wholesoy extract and soy isoflavones on apoptosis in prostate cancer cells. Experimental biology and medicine, 235 (1), 90–97.
- Huang, W., et al., 2014. Genistein-inhibited cancer stem cell-like properties and reduced chemoresistance of gastric cancer. International journal of molecular sciences, 15 (3), 3432–3443.
- Kim, J.J., et al., 2014. Nobiletin suppresses MMP-9 expression through modulation of p38 MAPKactivity in human dermal fibrobalsts. Biological and pharmaceutical bulletin, 37, 158–163.
- Kim, E.K., and Choi, E.J., 2015. Compromised MAPK signaling in human diseases: an update. Archives of toxicology, 89 (6), 867–882.
- Li, H.Q., Luo, Y., and Qiao, C.H., 2012. The mechanisms of anticancer agents by genistein and synthetic derivatives of isoflavone. Mini reviews in medicinal chemistry, 12 (4), 350–362.
- Liang, C.C., Park, A.Y., and Guan, J.L., 2007. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nature protocols, 2 (2), 329–333.
- Liu, Z., et al., 2017. Chemosensitizing effect of Paris Saponin I on Camptothecin and 10-hydroxycamptothecin in lung cancer cells via p38 MAPK, ERK, and Akt signaling pathways. European journal of medicinal chemistry, 125, 760–769.
- Lu, S., et al., 2017. Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP-2 and MMP-9 expression via the p38MAPK signaling pathway. Oncology letters, 14, 7577–7582.
- Luo, Y., et al., 2014. Apoptotic effect of genistein on human colon cancer cells via inhibiting the nuclear factor-kappa B (NF-kappaB) pathway. Tumor biology, 35 (11), 11483–11483.
- Maru, G.B., 2016. Understanding the molecular mechanisms of cancer prevention by dietary phytochemicals: from experimental models to clinical trials. World journal of biological chemistry, 7 (1), 88–99.
- Meng, L.Q., et al., 2018. Quinalizarin induces apoptosis through reactive oxygen species (ROS)-mediated mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription 3 (STAT3) signaling pathways in colorectal cancer cells. Medical science monitor, 24, 3710–3719.
- Neupane, S., Bray, F., and Auvinen, A., 2017. National economic and development indicators and international variation in prostate cancer incidence and mortality: an ecological analysis. World journal of urology, 35 (6), 851–858.
- Peisch, S.F., et al., 2017. Prostate cancer progression and mortality: a review of diet and lifestyle factors. World journal of urology, 35 (6), 867–874.
- Radisky, E.S., Raeeszadeh-Sarmazdeh, M., and Radisky, D.C., 2017. Therapeutic potential of matrix metalloproteinase inhibition in breast cancer. Journal of cellular biochemistry, 118, 3548–3531.
- Ranjbaran, J., et al., 2016. Matrix metalloproteinases 2 and 9 and MMP9/NGAL complex activity in women with PCOS. Reproduction, 151 (4), 305–311.
- Shafiee, G., et al., 2016. Genistein induces apoptosis and inhibits proliferation of HT29 colon cancer cells. International journal of molecular and cellular medicine, 5 (3), 178–191.,
- Shalini, S., et al., 2015. Old, new and emerging functions of caspases. Cell death and differentiation, 22, 526–539.
- Siegel, R.L., Miller, K.D., and Jemal, A., 2017. Cancer Statistics, 2017. CA: a cancer journal for clinicians, 67 (1), 7–30.
- Spagnuolo, C., et al., 2015. Genistein and cancer: current status, challenges, and future directions. Advances in nutrition, 6 (4), 408–419.,
- Su, S.J., et al., 2003. Effects of soy isoflavones on apoptosis induction and G2-M arrestin human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity. Nutrition and cancer, 45 (1), 113–123.
- van de Loosdrecht, A.A., et al., 1994. A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia. Journal of immunological methods, 174 (1–2), 311–320.
- Xu, L., and Bergan, R.C., 2006. Genistein inhibits matrix metalloproteinase type 2 activationand prostate cancer cell invasion by blocking the transforming growth factor beta-mediated activation of mitogen-activated protein kinase-activated protein kinase 2-27-kDa heat shock protein pathway. Molecular pharmacology, 70, 869–877.
- Yazdani, Y., et al., 2016. Genistein suppression of matrix metalloproteinase 2 (MMP-2) and vascular endothelial growth factor (VEGF) expression in mesenchymal stem cell like cells isolated from high and low grade gliomas. Asian pacific journal of cancer prevention: apjcp, 17 (12), 5303–5307.
- Zhang, Z., et al., 2018. Genistein promotes ionizing radiation-induced cell death by reducing cytoplasmic Bcl-xL levels in non-small cell lung cancer. Scientific reports, 8 (1), 328.
- Zhou, H., Chen, J., and Han, J., 2010. Activation of p38 and determination of its activity. Methods in molecular biology, 661, 75–89.