LncRNA GAS5 upregulates miR-214 through methylation to participate in cell apoptosis of sepsis

References

• Arfaras-Melainis, A., et al., 2020. Heart failure and sepsis: practical recommendations for the optimal management. Heart failure reviews, 25 (2), 183–194.
   PubMed Web of Science ®Google Scholar
• Cai, B., et al., 2015. The specific roles of JAK/STAT signaling pathway in sepsis. Inflammation, 38 (4), 1599–1608.
   PubMed Web of Science ®Google Scholar
• Cai, Z., et al., 2016. Suppression of P2X7/NF-κB pathways by Schisandrin B contributes to attenuation of lipopolysaccharide-induced inflammatory responses in acute lung injury. Archives of pharmacal research, 39 (4), 499–507.
   PubMed Web of Science ®Google Scholar
• Cohen, J., et al., 2015. Sepsis: a roadmap for future research. Lancet infectious diseases, 15 (5), 581–614.
   PubMed Web of Science ®Google Scholar
• Ge, C., Liu, J., and Dong, S., 2018. MIRNA-214 protects sepsis-induced myocardial injury. Shock (Augusta, GA), 50 (1), 112–118.
   PubMed Web of Science ®Google Scholar
• He, G., et al., 2017. Isoalantolactone inhibits LPS-induced inflammation via NF-κB inactivation in peritoneal macrophages and improves survival in sepsis. Biomedicine & pharmacotherapy, 90, 598–607.
   PubMed Web of Science ®Google Scholar
• Huang, W., et al., 2017. Long non-coding RNA PVT1 promote LPS-induced septic acute kidney injury by regulating TNFα and JNK/NF-κB pathways in HK-2 cells. International immunopharmacology, 47, 134–140.
   PubMed Web of Science ®Google Scholar
• Hung, Y.L., et al., 2017. Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response. Scientific reports, 7 (1), 46299.
   PubMedGoogle Scholar
• Jensen, I.J., et al., 2018. Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections. Plos pathogens, 14 (10), e1007405.
   PubMed Web of Science ®Google Scholar
• Kuzmich, N.N., et al., 2017. TLR4 signaling pathway modulators as potential therapeutics in inflammation and sepsis. Vaccines, 5 (4), 34.
   PubMed Web of Science ®Google Scholar
• Li, F., et al., 2018. LncRNA GAS5 overexpression reverses LPS-induced inflammatory injury and apoptosis through up-regulating KLF2 expression in ATDC5 chondrocytes. Cellular physiology and biochemistry, 45 (3), 1241–1251.
   PubMedGoogle Scholar
• Li, N., et al., 2019. Increased expression of lncRNA UCA1 and HULC is required for pro-inflammatory response during LPS induced sepsis in endothelial cells. Frontiers in physiology, 10, 608.
   PubMed Web of Science ®Google Scholar
• Liu, J., et al., 2017. miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer. Oncology letters, 14 (5), 5711–5718.
   PubMed Web of Science ®Google Scholar
• Liu, X., et al., 2019. Downregulation of lncRNA TUG1 contributes to the development of sepsis-associated acute kidney injury via regulating miR-142-3p/sirtuin 1 axis and modulating NF-κB pathway. Journal of cellular biochemistry, 120 (7), 11331–11341.
   Web of Science ®Google Scholar
• Meydan, C., Bekenstein, U., and Soreq, H., 2018. Molecular regulatory pathways link sepsis with metabolic syndrome: non-coding RNA elements underlying the sepsis/metabolic cross-talk. Frontiers in molecular neuroscience, 11, 189.
   PubMed Web of Science ®Google Scholar
• Meyer, N., et al., 2018. Temporal trends in incidence, sepsis-related mortality, and hospital-based acute care after sepsis. Critical care medicine, 46 (3), 354–360.
   PubMed Web of Science ®Google Scholar
• Peerapornratana, S., et al., 2019. Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment. Kidney international, 96 (5), 1083–1099.
   PubMed Web of Science ®Google Scholar
• Schulte, L.N., et al., 2019. ncRNAs in inflammatory and infectious diseases. Methods in molecular biology, 1912, 3–32.
   PubMedGoogle Scholar
• Zhang, B., et al., 2015. Cortistatin protects myocardium from endoplasmic reticulum stress induced apoptosis during sepsis. Molecular and cellular endocrinology, 406, 40–48.
   PubMed Web of Science ®Google Scholar
• Zhang, J., et al., 2016. miR-214 promotes apoptosis and sensitizes breast cancer cells to doxorubicin by targeting the RFWD2-p53 cascade. Biochemical and biophysical research communications, 478 (1), 337–342.
   PubMed Web of Science ®Google Scholar
• Zhang, Z.C., et al., 2014. Knockdown of miR-214 promotes apoptosis and inhibits cell proliferation in nasopharyngeal carcinoma. Plos one, 9 (1), e86149.
   PubMed Web of Science ®Google Scholar