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Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 128, 2022 - Issue 5
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Original Articles

Zaprinast and avanafil increase the vascular endothelial growth factor, vitamin D3, bone morphogenic proteins 4 and 7 levels in the kidney tissue of male rats applied the glucocorticoid

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Pages 1290-1296 | Received 15 Apr 2020, Accepted 05 May 2020, Published online: 18 May 2020

References

  • Affshana, M.M. and Ptriya, J., 2015. Healing mechanism in bone fracture. Journal of pharmaceutical sciences and research, 7, 441–442.
  • Alp, H.H., et al., 2017. The effect of PDE5 inhibitors on bone and oxidative damage in ovariectomy-induced osteoporosis. Experimental biology and medicine (Maywood, N.J.).), 242 (10), 1051–1061.
  • Bajraktari, G., et al., 2017. Cyclic guanosine monophosphate modulates accumulation of phosphodiesterase 5 inhibitors in human platelets. Biochemical pharmacology, 145, 54–63.
  • Böcker, W., et al., 2014. Short-term glucocorticoid treatment causes spinal osteoporosis in ovariectomized rats. European spine journal, 23 (11), 2437–2448.
  • Cardus, A., et al., 2006. 1,25-Dihydroxyvitamin D3 stimulates vascular smooth muscle cell proliferation through a VEGF-mediated pathway. Kidney international, 69, 1377–1384.
  • Cardus, A., et al., 2009. 1,25-dihydroxyvitamin D3 regulates VEGF production through a vitamin D response element in the VEGF promoter . Atherosclerosis, 204 (1), 85–89.
  • Carreira, A.C., et al., 2014. Bone morphogenetic proteins: structure, biological function and therapeutic applications. Archives of biochemistry and biophysics, 561, 64–73.
  • Celic, T., et al., 2018. Mechanisms of bone morphogenetic protein-7 protective effects against cold ischemia-induced renal injury in rats. Transplantation proceedings, 50, 3822–3830.
  • Cheng, P., et al., 2016. High-purity magnesium interference screws promote fibrocartilaginous entheses regeneration in the anterior cruciate ligament reconstruction rabbit model via accumulation of BMP-2 and VEGF. Biomaterials, 81, 14–26.
  • Comba, A., et al., 2015. Effect of sildenafil citrate on MDA, GSH, retinol, vitamin D3 and α -tocoferole levels in wound healing: diabetic rat model. Journal of applied biological sciences, 9 (3), 82–85.
  • Deng, Z.H., et al., 2018. Bone morphogenetic proteins for articular cartilage regeneration. Osteoarthritis and cartilage, 26 (9), 1153–1161.
  • Dumic-Cule, I., et al., 2018. Bone morphogenetic proteins in fracture repair. International orthopaedics, 42 (11), 2619–2626.
  • Frye, C.A. and Rhodes, M.E., 2003. Zaprinast, a phosphodiesterase 5 inhibitor, overcomes sexual dysfunction produced by fluoxetine, a selective serotonin reuptake inhibitor in Hamsters. Neuropsychopharmacology: official publication of the American college of neuropsychopharmacology, 28 (2), 310–316.
  • Gomez-Puerto, M.C., et al., 2019. Bone morphogenetic protein receptor signal transduction in human disease. The journal of pathology, 247 (1), 9–20.
  • Haubruck, P., et al., 2016. The treatment of nonunions with application of BMP-7 increases the expression pattern for angiogenic and inflammable cytokines: a matched pair analysis. Journal of inflammation research, 9, 155–165.
  • Huyut, Z., et al., 2018. Effects of the phosphodiesterase-5 (PDE-5) inhibitors, avanafil and zaprinast, on bone remodeling and oxidative damage in a rat model of glucocorticoid-induced osteoporosis. Medical science monitor basic research, 24, 47–58.
  • Huyut, Z., et al., 2020. Can zaprinast and avanafil induce the levels of angiogenesis, bone morphogenic protein 2, 4 and 7 in kidney of ovariectomized rats? Archives of physiology and biochemistry, 1–6. doi:10.1080/13813455.2020.1740743
  • Huyut, Z., et al., 2020a. Stimulating effects of vardenafil, tadalafil, and udenafil on vascular endothelial growth factor, angiogenesis, vitamin D3, bone morphogenic proteins in ovariectomized rats. Archives of physiology and biochemistry. doi:10.1080/13813455.2020.1755695
  • Kim, H., et al., 2008. Dexamethasone coordinately regulates angiopoietin-1 and VEGF: a mechanism of glucocorticoid-induced stabilization of blood-brain barrier. Biochemical and biophysical research communications, 372 (1), 243–248.
  • Kim, H.S., et al., 2018. Effects of 1,25-dihydroxyvitamin D3 on the differentiation of MC3T3-E1 osteoblast-like cells. Journal of periodontal and implant science, 48 (1), 34–46.
  • Kim, S.K., et al., 2016. Comparative study of BMP-2 alone and combined with VEGF carried by hydrogel for maxillary alveolar bone regeneration. Tissue engineering and regenerative medicine, 13 (2), 171–181.
  • Kotera, J., et al., 2012. Avanafil, a potent and highly selective phosphodiesterase-5 inhibitor for erectile dysfunction. The journal of urology, 188 (2), 668–674.
  • Liu, G., et al., 2010. Chronic administration of sildenafil modified the impaired VEGF system and improved the erectile function in rats with diabetic erectile dysfunction. The journal of sexual medicine, 7 (12), 3868–3878.
  • Mancini, L., et al., 2000. The biphasic effects of nitric oxide in primary rat osteoblasts are cGMP dependent. Biochemical and biophysical research communications, 274 (2), 477–481.
  • Pal, S., et al., 2020. Skeletal restoration by phosphodiesterase 5 inhibitors in osteopenic mice: evidence of osteoanabolic and osteoangiogenic effects of the drugs. Bone, 135, 115305.
  • Pepe, J., et al., 2017. The effect of parathyroid hormone (1-84) treatment on serum bone morphogenetic protein 4 and vascular endothelial growth factor in postmenopausal women with established osteoporosis. Journal of endocrinological investigation, 40 (6), 663–667.
  • Raftery, R.M., et al., 2018. Delivery of the improved BMP-2-Advanced plasmid DNA within a gene-activated scaffold accelerates mesenchymal stem cell osteogenesis and critical size defect repair. Journal of controlled release, 283, 20–31.
  • Schlaeppi, J.M., et al., 1997. 1,25-dihydroxyvitamin D3 Induces the expression of vascular endothelial growth factor in osteoblastic cells. Endocrine research, 23 (3), 213–229.
  • Segredo-Morales, E., et al., 2017. BMP delivery systems for bone regeneration: healthy vs osteoporotic population. Journal of drug delivery science and technology, 42, 107–118.
  • Shen, G., et al., 2016. Effect of glucocorticoid withdrawal on glucocorticoid inducing bone impairment. Biochemical and biophysical research communications, 477 (4), 1059–1064.
  • Shi, C., et al., 2014. MicroRNA-17/20a inhibits glucocorticoid-induced osteoclast differentiation and function through targeting RANKL expression in osteoblast cells. Bone, 68, 67–75.
  • Shi, S. R., et al., 1996. A novel approach to immunohistochemistry on routinely processed tissue sections. In: J. Gu, ed. Analitical morphology theory, applications and protocols. 1st ed. Basel: Birkhauser, 1–40.
  • Wang, W., et al., 2016. A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4. Carbohydrate polymers, 144, 305–314.
  • Wang, X., et al., 2018. Alteration of bone mineral density differs between genders in obese subjects after laparoscopic sleeve gastrectomy: bone morphogenetic protein 4 may count. Obesity surgery, 28 (10), 3221–3226.
  • Wetzl, V., et al., 2017. Differences in the renal antifibrotic cGMP/cGKI-dependent signaling of serelaxin, zaprinast, and their combination. Naunyn-schmiedeberg's archives of pharmacology, 390 (9), 939–948.
  • Xu, Y.R., et al., 2018. The characterization and potential roles of bone morphogenetic protein 7 during spermatogenesis in Chinese mitten crab Eriocheir sinensis. Gene, 673, 119–129.
  • Yaman, F., et al., 2011. Phosphodiesterase-5 inhibitors may facilitate bone defect recovery. European review for medical and pharmacological sciences, 15 (11), 1301–1305.

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