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Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 128, 2022 - Issue 6
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Original Articles

Azelastine a potent antihistamine agent, as hypolipidemic and modulator for aortic calcification in diabetic hyperlipidemic rats model

ORCID Icon, , &
Pages 1611-1618 | Received 27 May 2020, Accepted 17 Jun 2020, Published online: 02 Jul 2020

References

  • Agbecha, A., Usoro, A.J., and Gberindyer, J.S.A., 2018. Relationship of serum alkaline phosphatase with atherogenic indices in apparently healthy men, Makurdi, Nigeria. International journal of clinical and experimental physiology, 5 (1), 22–29.
  • Alfadda, A.A., et al., 2013. Association between osteocalcin, metabolic syndrome, and cardiovascular risk factors: role of total and undercarboxylated osteocalcin in patients with type 2 diabetes. International journal of endocrinology, 2013, 197519.
  • Allison, M.A. and Wright, C.M., 2004. A comparison of HDL and LDL cholesterol for prevalent coronary calcification. International journal of cardiology, 95 (1), 55–60.
  • Allison, M.A., Wright, M., and Tiefenbrun, J., 2003. The predictive power of low-density lipoprotein cholesterol for coronary calcification. International journal of cardiology, 90 (2-3), 281–289.
  • Arin, R.M., et al., 2017. Expression of adenosine A2B receptor and adenosine deaminase in rabbit gastric mucosa ECL cells. Molecules, 22 (4), 625.,
  • Bini, A., et al., 1999. Noncollagenous bone matrix proteins, calcification, and thrombosis in carotid artery atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology, 19 (8), 1852–1861.
  • Boström, K.I., Rajamannan, N.M., and Towler, D.A., 2011. The regulation of valvular and vascular sclerosis by osteogenic morphogens. Circulation research, 109 (5), 564–577.
  • Chistiakov, D.A., et al., 2017. Paraoxonase and atherosclerosis-related cardiovascular diseases. Biochimie, 132, 19–27.
  • Choi, S.-Y., et al., 2011. The conformation and CETP inhibitory activity of [10]-dehydrogingerdione isolated from Zingiber officinale. Archives of pharmacal research, 34 (5), 727–731.
  • Cockerill, G.W., et al., 1995. High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules. Arteriosclerosis, thrombosis, and vascular biology, 15 (11), 1987–1994.,
  • Elseweidy, M.M., et al., 2013. 10-Dehydrogingerdione raises HDL-cholesterol through a CETP inhibition and wards off oxidation and inflammation in dyslipidemic rabbits. Atherosclerosis, 231 (2), 334–340.
  • Elseweidy, M.M., et al., 2016. Policosanol as a new inhibitor candidate for vascular calcification in diabetic hyperlipidemic rats. Experimental biology and medicine (Maywood, N.J.), 241 (17), 1943–1949.
  • Elseweidy, M.M., et al., 2019. Potential therapeutic roles of 10-dehydrogingerdione and/or pentoxifylline against calcium deposition in aortic tissues of high dietary cholesterol-fed rabbits. Molecular and cellular biochemistry, 453 (1–2), 131–142.
  • Friedewald, W.T., Levy, R.I., and Fredrickson, D.S., 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical chemistry, 18 (6), 499–502.
  • Haas, M.J., et al., 2017. high-throughput analysis identifying drugs that regulate apolipoprotein A-I Synthesis. Assay and drug development technologies, 15 (8), 362–371.
  • Haas, M.J., et al., 2018. Inhibition of hepatic apolipoprotein A-I gene expression by histamine. European journal of pharmacology, 823, 49–57.
  • Haas, M.J., et al., 2018. Regulation of apolipoprotein A-I gene expression by the histamine H1 receptor: requirement for NF-κB. Life sciences, 208, 102–110.
  • Herink, M. and Ito, M. K., 2018. Medication induced changes in lipid and lipoproteins, in Endotext [Internet]. MDText.com, Inc.
  • Jeziorska, M., McCollum, C., and Woolley, D.E., 1998. Calcification in atherosclerotic plaque of human carotid arteries: associations with mast cells and macrophages. The journal of pathology, 185 (1), 10–17.
  • Kovanen, P.T. and Bot, I., 2017. Mast cells in atherosclerotic cardiovascular disease – activators and actions. European journal of pharmacology, 816, 37–46.
  • Lewis, G.F., 2006. Determinants of plasma HDL concentrations and reverse cholesterol transport. Current opinion in cardiology, 21 (4), 345–352.
  • Lindstedt, K.A., 1993. Inhibition of macrophage-mediated low density lipoprotein oxidation by stimulated rat serosal mast cells. The journal of biological chemistry, 268 (11), 7741–7746.
  • Liu, C.-L., Zhang, J.-Y., and Shi, G.-P., 2016. Interaction between allergic asthma and atherosclerosis. Translational research : the journal of laboratory and clinical medicine, 174, 5–22.
  • Low Wang, C.C., et al., 2016. Clinical update: cardiovascular disease in diabetes mellitus: atherosclerotic cardiovascular disease and heart failure in type 2 diabetes mellitus – mechanisms, management, and clinical considerations. Circulation, 133 (24), 2459–2502.,
  • McTavish, D. and Sorkin, E.M., 1989. Azelastine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. Drugs, 38 (5), 778–800.
  • Mody, N., et al., 2001. Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free radical biology & medicine, 31 (4), 509–519.
  • Morgan, A., et al., 2016. Cholesterol metabolism: A review of how ageing disrupts the biological mechanisms responsible for its regulation. Ageing research reviews, 27, 108–124.
  • Orakzai, S.H., et al., 2009. Non-HDL cholesterol is strongly associated with coronary artery calcification in asymptomatic individuals. Atherosclerosis, 202 (1), 289–295.
  • Panh, L., et al., 2017. Association between serum alkaline phosphatase and coronary artery calcification in a sample of primary cardiovascular prevention patients. Atherosclerosis, 260, 81–86.
  • Parhami, F., et al., 2002. High-density lipoprotein regulates calcification of vascular cells. Circulation research, 91 (7), 570–576.
  • Raffield, L.M., et al., 2013. Impact of HDL genetic risk scores on coronary artery calcified plaque and mortality in individuals with type 2 diabetes from the Diabetes Heart Study. Cardiovascular diabetology, 12 (1), 95.
  • Rajamannan, N.M., et al., 2005. Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve. Heart (British Cardiac Society), 91 (6), 806–810.
  • Sage, A.P., Tintut, Y., and Demer, L.L., 2010. Regulatory mechanisms in vascular calcification. Nature reviews. Cardiology, 7 (9), 528–536.
  • Savinov, A.Y., et al., 2015. Transgenic overexpression of tissue‐nonspecific alkaline phosphatase (TNAP) in vascular endothelium results in generalized arterial calcification. Journal of the American Heart Association, 4 (12), e002499.
  • Schubert, M.L., 2016. Gastric acid secretion. Current opinion in gastroenterology, 32 (6), 452–460.
  • Schwartz, L., et al., 1987. Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells. The journal of immunology, 138 (8), 2611–2615.
  • Tabas, I., Williams, K.J., and Borén, J., 2007. Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation, 116 (16), 1832–1844.
  • Talarico, G.P., et al., 2017. Cocaine and coronary artery diseases: a systematic review of the literature. Journal of cardiovascular medicine (Hagerstown, Md.), 18 (5), 291–294.
  • Thangam, E.B., et al., 2018. The role of histamine and histamine receptors in mast cell-mediated allergy and inflammation: the hunt for new therapeutic targets. Frontiers in immunology, 9, 1873.
  • Walia, D.S., et al., 2012. Human mast cells (HMC-1 5C6) enhance interleukin-6 production by quiescent and lipopolysaccharide-stimulated human coronary artery endothelial cells. Mediators of inflammation, 2012, 274347.
  • Wang, H-j., et al., 2017. IP-10/CXCR3 axis promotes the proliferation of vascular smooth muscle cells through ERK1/2/CREB signaling pathway. Cell biochemistry and biophysics, 75 (1), 139–147.
  • Wilkins, J.T., et al., 2016. Discordance between apolipoprotein B and LDL-cholesterol in young adults predicts coronary artery calcification: the CARDIA study. Journal of the American College of Cardiology, 67 (2), 193–201.
  • Williams, P.B., Crandall, E., and Sheppard, J.D., 2010. Azelastine hydrochloride, a dual-acting anti-inflammatory ophthalmic solution, for treatment of allergic conjunctivitis. Clinical ophthalmology (Auckland, NZ), 4, 993.
  • Yuhanna, I.S., et al., 2001. High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase. Nature medicine, 7 (7), 853–857.

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