Deletion of toll-like receptor 4 ameliorates diabetic retinopathy in mice

References

• Cheung, N., Mitchell, P., and Wong, T.Y., 2010. Diabetic retinopathy. Lancet (London, England)), 376 (9735), 124–136.
   PubMed Web of Science ®Google Scholar
• Chi, W., et al., 2014. Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma. Proceedings of the national academy of sciences of the United States of America, 111 (30), 11181–11186.
   PubMed Web of Science ®Google Scholar
• Devaraj, S., et al., 2008. Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. The journal of clinical endocrinology & metabolism, 93 (2), 578–583.
   PubMed Web of Science ®Google Scholar
• Devaraj, S., Tobias, P., and Jialal, I., 2011. Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes. Cytokine, 55 (3), 441–445.
   PubMed Web of Science ®Google Scholar
• Han, W., et al., 2019. Huangkui capsule alleviates renal tubular epithelial-mesenchymal transition in diabetic nephropathy via inhibiting NLRP3 inflammasome activation and TLR4/NF-κB signaling . Phytomedicine: international journal of phytotherapy and phytopharmacology, 57, 203–214.
   PubMed Web of Science ®Google Scholar
• Heng, L.Z., et al., 2013. Diabetic retinopathy: pathogenesis, clinical grading, management and future developments. Diabetic medicine : a journal of the British Diabetic Association, 30 (6), 640–650.
   PubMed Web of Science ®Google Scholar
• Hui, Y., and Yin, Y., 2018. MicroRNA-145 attenuates high glucose-induced oxidative stress and inflammation in retinal endothelial cells through regulating TLR4/NF-κB signaling . Life sciences, 207, 212–218.
   PubMed Web of Science ®Google Scholar
• Joseph, C., et al., 1991. Sterile vs clean urinary catheterization. Journal of the American Geriatrics Society, 39 (10), 1042–1043.
   PubMed Web of Science ®Google Scholar
• Kawai, T., and Akira, S., 2007. Signaling to NF-kappaB by Toll-like receptors. Trends in molecular medicine, 13 (11), 460–469.
   PubMed Web of Science ®Google Scholar
• Li, J., et al., 2018. Ursolic acid alleviates inflammation and against diabetes‑induced nephropathy through TLR4‑mediated inflammatory pathway. Molecular medicine reports, 18 (5), 4675–4681.
   PubMed Web of Science ®Google Scholar
• Liang, H., et al., 2019. Toll-like receptor 4 promotes high glucose-induced catabolic and inflammatory responses in chondrocytes in an NF-kappaB-dependent manner. Life sciences., 228, 258–265.
   PubMed Web of Science ®Google Scholar
• Liu, X., et al., 2020. microRNA-499-3p inhibits proliferation and promotes apoptosis of retinal cells in diabetic retinopathy through activation of the TLR4 signaling pathway by targeting IFNA2. Gene, 741, 144539.
   PubMed Web of Science ®Google Scholar
• Liu, Z., et al., 2012. Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II-induced abdominal aortic aneurysm in mice. Circulation research, 111 (10), 1261–1273.
   PubMed Web of Science ®Google Scholar
• Lu, Y.C., Yeh, W.C., and Ohashi, P.S., 2008. LPS/TLR4 signal transduction pathway. Cytokine, 42 (2), 145–151.
   PubMed Web of Science ®Google Scholar
• Nunes, K.P., et al., 2018. Blockade of toll-like receptor 4 attenuates erectile dysfunction in diabetic rats. J Sex Med, 15 (9), 1235–1245.
   PubMed Web of Science ®Google Scholar
• Rubsam, A., Parikh, S., and Fort, P.E., 2018. Role of inflammation in diabetic retinopathy. International journal of molecular sciences., 19, 942.
   PubMed Web of Science ®Google Scholar
• Sen, S., and Chakraborty, R., 2015. Treatment and diagnosis of diabetes mellitus and its complication: advanced approaches. Mini reviews in medicinal chemistry, 15 (14), 1132–1133.
   PubMed Web of Science ®Google Scholar
• Szasz, T., et al., 2016. Toll-like receptor 4 activation contributes to diabetic bladder dysfunction in a murine model of type 1 diabetes. Diabetes, 65 (12), 3754–3764.
   PubMed Web of Science ®Google Scholar
• Wang, Y., et al., 2019. Apocynin ameliorates diabetic retinopathy in rats: Involvement of TLR4/NF-κB signaling pathway. International immunopharmacology, 73, 49–56.
   PubMed Web of Science ®Google Scholar
• Wang, Y.L., et al., 2015. Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats. Graefe's archive for clinical and experimental ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie, 253 (3), 389–398.
   PubMed Web of Science ®Google Scholar
• Ye, E.A., and Steinle, J.J., 2016. miR-146a attenuates inflammatory pathways mediated by TLR4/NF-κB and TNFα to protect primary human retinal microvascular endothelial cells grown in high glucose. Mediators of inflammation, 2016, 3958453.
   PubMed Web of Science ®Google Scholar
• Yuan, S., et al., 2018. The role of TLR4 on PGC-1α-mediated oxidative stress in tubular cell in diabetic kidney disease. Oxidative medicine and cellular longevity, 2018, 6296802.
   PubMed Web of Science ®Google Scholar
• Zaharieva, E.T., Kamenov, Z.A., and Savov, A.S., 2017. TLR4 polymorphisms seem not to be associated with prediabetes and type 2 diabetes but predispose to diabetic retinopathy; TLR4 polymorphisms in glucose continuum. Endocrine regulations, 51 (3), 137–144.
   PubMedGoogle Scholar
• Zhu, L., et al., 2018. Berberine ameliorates diabetic nephropathy by inhibiting TLR4/NF-κB pathway. Biological research, 51 (1), 9.
   PubMedGoogle Scholar
• Zhu, S.H., et al., 2017. Paeoniflorin suppressed high glucose-induced retinal microglia MMP-9 expression and inflammatory response via inhibition of TLR4/NF-κB pathway through upregulation of SOCS3 in diabetic retinopathy. Inflammation, 40 (5), 1475–1486.
   PubMed Web of Science ®Google Scholar