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Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 129, 2023 - Issue 3
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Original Articles

Bridelia ferruginea inhibits key carbohydrate digesting enzyme and intestinal glucose absorption and modulates glucose metabolism in diabetic rats

ORCID Icon, , , ORCID Icon & ORCID Icon
Pages 671-681 | Received 29 Jul 2020, Accepted 02 Dec 2020, Published online: 28 Dec 2020

References

  • Abro, M.U.R., et al., 2018. Association of serum liver enzyme Alanine Aminotransferase (ALT) in patients with type 2 diabetes. Pakistan journal of medical sciences, 34 (4), 839–843.
  • Ademiluyi, A.O., and Oboh, G., 2013. Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro. Experimental and toxicologic pathology, 65 (3), 305–309.
  • Adewale, O., and Oloyede, O., 2012. Hypoglycemic activity of aqueous extract of the bark of Bridelia ferruginea in normal and alloxan-induced diabetic rats. Prime research on biotechnology, 2, 53–56.
  • Afolabi, O.B., Oloyede, O.I., and Agunbiade, S.O., 2018. Inhibitory potentials of phenolic-rich extracts from Bridelia ferruginea on two key carbohydrate-metabolizing enzymes and Fe2+-induced pancreatic oxidative stress. Journal of integrative medicine, 16 (3), 192–198.
  • Akuodor, G., et al., 2012. Ulcer-protective and antidiarrhoeal effects of the aqueous stem bark extract of Bridelia ferruginea in rodents. Pharmacologia, 3 (11), 591–597.
  • Awodele, O., et al., 2015. Toxicological evaluation of the aqueous stem bark extract of Bridelia ferruginea (Euphorbiaceae) in rodents. Interdisciplinary toxicology, 8 (2), 89–98.
  • Bakoma, B., et al., 2011. Preventive effect of Bridelia ferruginea Benth against high-fructose diet induced glucose intolerance, oxidative stress and hyperlipidemia in male Wistar rats. Journal of pharmacology and toxicology, 6 (3), 249–257.
  • Bakoma, B., et al., 2014. Effect of Bridelia ferruginea Benth (Euphorbiaceae) ethyl acetate and acetone fractions on insulin resistance in fructose drinking mice. Journal of ethnopharmacology, 153 (3), 896–899.
  • Balamurugan, R., Duraipandiyan, V., and Ignacimuthu, S., 2011. Antidiabetic activity of γ-sitosterol isolated from Lippia nodiflora L. in streptozotocin induced diabetic rats. European journal of pharmacology, 667 (1–3), 410–418.
  • Bezerra, R.M., et al., 2000. A high fructose diet affects the early steps of insulin action in muscle and liver of rats. The journal of nutrition, 130 (6), 1531–1535.
  • Bolajoko, E.B., Akinosun, O.M., and Khine, A.A., 2020. Hyperglycemia-induced oxidative stress in the development of diabetic foot ulcers. Diabetes, Academic press, 35–48.
  • Catena, C., et al., 2003. Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension. American journal of hypertension, 16 (11 Pt 1), 973–978.
  • Chowdhury, P., and Soulsby, M., 2002. Lipid peroxidation in rat brain is increased by simulated weightlessness and decreased by a soy-protein diet. Annals of clinical and laboratory science, 32 (2), 188–192.
  • Chukwuma, C.I., et al., 2018. Erythritol reduces small intestinal glucose absorption, increases muscle glucose uptake, improves glucose metabolic enzymes activities and increases expression of Glut-4 and IRS-1 in type 2 diabetic rats. European journal of nutrition, 57 (7), 2431–2414.
  • Conway, B.N., et al., 2018. The obesity epidemic and rising diabetes incidence in a low-income racially diverse southern US cohort. PLoS one, 13 (1), e0190993.
  • Dhulasavant, V., et al., 2010. Antihyperlipidemic activity of Cinnamomum tamala Nees. on high cholesterol diet induced hyperlipidemia. International journal of pharmtech research, 2 (4), 2517–2521.
  • Einarson, T.R., et al., 2018. Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007–2017. Cardiovascular diabetology, 17 (1), 1–19.
  • Elahi, M.M., Naseem, K.M., and Matata, B.M., 2007. Nitric oxide in blood. The nitrosative-oxidative disequilibrium hypothesis on the pathogenesis of cardiovascular disease. The FEBS journal, 274 (4), 906–923.
  • Ellman, G.L., 1959. Tissue sulfhydryl groups. Archives of biochemistry and biophysics, 82 (1), 70–77.
  • Erukainure, O.L., et al., 2020. Dacryodes edulis (G. Don) HJ Lam modulates glucose metabolism, cholinergic activities and Nrf2 expression, while suppressing oxidative stress and dyslipidemia in diabetic rats. Journal of ethnopharmacology, 255, 112744.
  • Espineli, D.L., et al., 2014. Cytotoxic and antimicrobial compounds from Cinnamomum cebuense Kosterm.(Lauraceae). Pharmaceutical chemistry journal, 48 (9), 598–602.
  • Faria, A., and Persaud, S.J., 2017. Cardiac oxidative stress in diabetes: mechanisms and therapeutic potential. Pharmacology & therapeutics, 172, 50–62.
  • Forouhi, N.G., and Wareham, N.J., 2019. Epidemiology of diabetes. Medicine, 47 (1), 22–27.
  • Gaikwad, B.S., Krishna Mohan, G., and Sandhya Rani, M., 2014. Phytochemicals for diabetes management. Pharmaceutical crops, 5 (1), 11–28.
  • Ghadyale, V., et al., 2012. Effective control of postprandial glucose level through inhibition of intestinal alpha glucosidase by Cymbopogon martinii (Roxb). Evidence-based complementary and alternative medicine: ECAM, 2012, 372909–372906.
  • Gomes, M.D.B., et al., 2013. Impact of diabetes on cardiovascular disease: an update. International journal of hypertension, 2013, 653789–653715.
  • Gupta, R., et al., 2011. Antidiabetic and antioxidant potential of β-sitosterol in streptozotocin-induced experimental hyperglycemia. Journal of diabetes, 3 (1), 29–37.
  • Hadwan, M.H., and Abed, H.N., 2016. Data supporting the spectrophotometric method for the estimation of catalase activity. Data in brief, 6, 194–199.
  • Hassan, Z., et al., 2010. Antidiabetic properties and mechanism of action of Gynura procumbens water extract in streptozotocin-induced diabetic rats. Molecules, 15 (12), 9008–9023.
  • Hudish, L.I., Reusch, J.E., and Sussel, L., 2019. β cell dysfunction during progression of metabolic syndrome to type 2 diabetes. The journal of clinical investigation, 129 (10), 4001–4008.
  • Ibrahim, M.A., et al., 2016. Butanol fraction of Parkia biglobosa (Jacq.) G. Don leaves enhance pancreatic β-cell functions, stimulates insulin secretion and ameliorates other type 2 diabetes-associated complications in rats. Journal of ethnopharmacology, 183, 103–111.
  • IDF. 2017., International diabetes federation atlas. International diabetes federation Brussels, Belgium, 8th ed. Brussels: IDF.
  • IDF. 2019., International diabetes federation atlas. International diabetes federation Busan, South Korea, 9th ed. Busan: IDF.
  • Inthongkaew, P., et al., 2017. α-Glucosidase and pancreatic lipase inhibitory activities and glucose uptake stimulatory effect of phenolic compounds from Dendrobium formosum. Revista brasileira de farmacognosia, 27 (4), 480–487.
  • Jha, J.C., et al., 2016. Diabetes and kidney disease: role of oxidative stress. Antioxidants & redox signaling, 25 (12), 657–684.
  • Kakkar, P., Das, B., and Viswanathan, P., 1984. A modified spectrophotometric assay of superoxide dismutase. Indian journal of biochemistry & biophysics, 21 (2), 130–132.
  • Karan, S.K., et al., 2012. Isolation of-sitosterol and evaluation of antidiabetic activity of Aristolochia indica in alloxan-induced diabetic mice with a reference to in vitro antioxidant activity. Journal of medicinal plants research, 6 (7), 1219–1223.
  • Kohei, K., 2010. Pathophysiology of type 2 diabetes and its treatment policy. Japan medical association journal, 53 (1), 41–46.
  • Kushiyama, A., et al., 2014. Linking uric acid metabolism to diabetic complications. World journal of diabetes, 5 (6), 787–795.
  • Lowry, O.H., et al., 1951. Protein measurement with the Folin phenol reagent. Journal of biological chemistry, 193 (1), 265–275.
  • Miranda-Díaz, A.G., et al., 2016. Oxidative stress in diabetic nephropathy with early chronic kidney disease. Journal of diabetes research, 2016, 1–7.
  • Neha, K., et al., 2019. Medicinal prospects of antioxidants: a review. European journal of medicinal chemistry, 178, 687–704.
  • Nicolis, E., et al., 2008. Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells. International immunopharmacology, 8 (12), 1672–1680.
  • Njamen, D., et al., 2013. Effect of Bridelia ferruginea (Euphorbiaceae) leaf extract on sucrose-induced glucose intolerance in rats. Tropical journal of pharmaceutical research, 11 (5), 759–765.
  • Olajide, O.A., et al., 2012a., 2012. Bridelia ferruginea produces antineuroinflammatory activity through inhibition of nuclear factor-kappa B and p38 MAPK signalling. Evidence-based complementary and alternative medicine: ECAM, 2012, 546873–546878.
  • Omoboyowa, D.A., Karigidi, K.O., and Aribigbola, T.C., 2020. Bridelia ferruginea Benth leaves attenuates diabetes nephropathy in STZ-induced rats via targeting NGAL/KIM-1/cystatin c gene. Clinical phytoscience, 6 (1), 1–10.
  • Oyebode, O.A., et al., 2018. Boerhaavia diffusa inhibits key enzymes linked to type 2 diabetes in vitro and in silico; and modulates abdominal glucose absorption and muscle glucose uptake ex vivo. Biomedicine & pharmacotherapy = Biomedecine & Pharmacotherapie, 106, 1116–1125.
  • Oyebode, O.A., et al., 2019. Crassocephalum rubens, a leafy vegetable, suppresses oxidative pancreatic and hepatic injury and inhibits key enzymes linked to type 2 diabetes: an ex vivo and in silico study. Journal of food biochemistry, 43 (8), e12930.
  • Rasouli, H., et al., 2017. Differential α-amylase/α-glucosidase inhibitory activities of plant-derived phenolic compounds: a virtual screening perspective for the treatment of obesity and diabetes. Food & function, 8 (5), 1942–1954.
  • Sagoo, M.K., and Gnudi, L., 2018. Diabetic nephropathy: is there a role for oxidative stress? Free radical biology & medicine, 116, 50–63.
  • Shohat, N., et al., 2017. Serum fructosamine: a simple and inexpensive test for assessing preoperative glycemic control. The journal of bone and joint surgery, 99 (22), 1900–1907.,
  • Smith, I.K., Vierheller, T.L., and Thorne, C.A., 1988. Assay of glutathione reductase in crude tissue homogenates using 5, 5′-dithiobis (2-nitrobenzoic acid). Analytical biochemistry, 175 (2), 408–413.
  • Song, Y.S., et al., 2016. Comparison of the usefulness of the updated homeostasis model assessment (HOMA2) with the original HOMA1 in the prediction of type 2 diabetes mellitus in Koreans. Diabetes & metabolism journal, 40 (4), 318–325.
  • Spahis, S., Borys, J.-M., and Levy, E., 2017. Metabolic syndrome as a multifaceted risk factor for oxidative stress. Antioxidants & redox signaling, 26 (9), 445–461.
  • Štěpánek, L., et al., 2019. Associations between homeostasis model assessment (HOMA) and routinely examined parameters in individuals with metabolic syndrome. Physiological research, 68 (6), 921–930.
  • Taiwo, I., Adewumi, O., and Odeigah, P., 2012. Assessment of Bridelia ferruginea benth for its therapeutic potential in pregnancy-induced impaired glucose tolerance in rats. International journal of medicine and biomedical research, 1 (1), 49–55.
  • Tanabe, K., et al., 2017. Interorgan crosstalk contributing to β-cell dysfunction. Journal of diabetes research, 2017, 3605178–3605178.
  • Thazhath, S.S., et al., 2016. The glucagon-like peptide 1 receptor agonist exenatide inhibits small intestinal motility, flow, transit, and absorption of glucose in healthy subjects and patients with type 2 diabetes: a randomized controlled trial. Diabetes, 65 (1), 269–275.
  • Toma, A., et al., 2014. Intestinal α-glucosidase and some pancreatic enzymes inhibitory effect of hydroalcholic extract of Moringa stenopetala leaves. BMC complementary and alternative medicine, 14 (1), 180–185.
  • Tran, L.T., Yuen, V.G., and McNeill, J.H., 2009. The fructose-fed rat: a review on the mechanisms of fructose-induced insulin resistance and hypertension. Molecular and cellular biochemistry, 332 (1–2), 145–159.
  • Tricò, D., et al., 2016. Manipulating the sequence of food ingestion improves glycemic control in type 2 diabetic patients under free-living conditions. Nutrition & diabetes, 6 (8), e226–e226.
  • Wilson, R.D., and Islam, M.S., 2012. Fructose-fed streptozotocin-injected rat: an alternative model for type 2 diabetes. Pharmacological reports, 64 (1), 129–139.
  • Yin, Z., et al., 2014. α-Glucosidase inhibitors isolated from medicinal plants. Food science and human wellness, 3 (3–4), 136–174.
  • Yousefi, A., et al., 2015. Novel curcumin-based pyrano[2,3-d]pyrimidine anti-oxidant inhibitors for α-amylase and α-glucosidase: implications for their pleiotropic effects against diabetes complications. International journal of biological macromolecules, 78, 46–55.
  • Zeb, M., et al., 2017. Isolation and biological activity of β-sitosterol and stigmasterol from the roots of Indigofera heterantha. Pharmacy and pharmacology international journal, 5 (5), 204–207.

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