Advanced search
Publication Cover
Ophthalmic Genetics Volume 42, 2021 - Issue 3
Submit an article Journal homepage
107
Views
1
CrossRef citations to date
0
Altmetric
Research Reports

Calculation of test-retest variability in phase I/IIa clinical trials for Inherited Retinal Degenerations

Jacob Jeries Abou-Hannaa Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA;b University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan, USAORCID Iconhttps://orcid.org/0000-0003-1233-0093View further author information
ORCID Icon,
Chris A. Andrewsc Department of Ophthalmology and Visual Sciences, Center for Eye Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA;d Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USAView further author information
,
Naheed W. Khanc Department of Ophthalmology and Visual Sciences, Center for Eye Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USAView further author information
,
David C. Muschc Department of Ophthalmology and Visual Sciences, Center for Eye Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA;d Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA;e Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USAORCID Iconhttps://orcid.org/0000-0002-4164-3841View further author information
ORCID Icon &
K. Thiran Jayasunderac Department of Ophthalmology and Visual Sciences, Center for Eye Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4895-4818View further author information
ORCID Icon
Pages 283-290 | Received 07 Jan 2021, Accepted 20 Feb 2021, Published online: 17 Mar 2021

References

  • Bittner AK, Mistry A, Nehmad L, Khan R, Dagnelie G. Improvements in test–retest variability of static automated perimetry by censoring results with low sensitivity in retinitis Pigmentosa. Transl Vis Sci Technol. 2020 Nov 20;9(12):26. doi:10.1167/tvst.9.12.26.
  • Bland JM, Altman D. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986 Feb 8;327(8476):307–10. doi:10.1016/S0140-6736(86)90837-8.
  • Jeffrey BG, Cukras CA, Vitale S, Turriff A, Bowles K, Sieving PA. Test–retest intervisit variability of functional and structural parameters in X-Linked retinoschisis. Transl Vis Sci Technol. [Internet]. 2014 Oct 3 [accessed 2019 Oct 9];3(5). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187428/.
  • Atkinson G, Nevill AM.Statistical methods for assessing measurement error (Reliability) in variables relevant to sports medicine. Sports Med. 1998;26(4):217–38. doi:10.2165/00007256-199826040-00002.
  • Dedania VS, Liu JY, Schlegel D, Andrews CA, Branham K, Khan NW, Musch DC, Heckenlively JR, Jayasundera KT. Reliability of kinetic visual field testing in children with mutation-proven retinal dystrophies: implications for therapeutic clinical trials. Ophthalmic Genet. 2018 Jan 2;39(1):22–28. doi:10.1080/13816810.2017.1329447.
  • Liu H, Bittencourt MG, Wang J, Sophie R, Annam R, Ibrahim MA, Sepah YJ, Moradi A, Scholl HPN, Nguyen QD, et al. Assessment of central retinal sensitivity employing two types of microperimetry devices. Transl Vis Sci Technol. [Internet]. 2014 Sep 12 [accessed 2020 May 19];3(5). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164074/.
  • Steinberg JS, Saßmannshausen M, Pfau M, Fleckenstein M, Finger RP, Holz FG, Schmitz-Valckenberg S, Evaluation of two systems for fundus-controlled scotopic and mesopic perimetry in eye with age-related macular degeneration. Transl Vis Sci Technol. [Internet]. 2017 Jul 13 [accessed 2020 Jul 19];6(4). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509379/.
  • Cukras C, Wiley HE, Jeffrey BG, Sen HN, Turriff A, Zeng Y, Vijayasarathy C, Marangoni D, Ziccardi L, Kjellstrom S, et al. Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: initial Findings from a Phase I/IIa Trial by Intravitreal Delivery. Mol Ther. 2018 Sep 5;26(9):2282–94. doi:10.1016/j.ymthe.2018.05.025.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.