Functional imaging of mitochondria in genetically confirmed retinal dystrophies using flavoprotein fluorescence

References

• Barot M, Gokulgandhi MR, Mitra AK. 2011. Mitochondrial dysfunction in retinal diseases. Curr Eye Res. 36(12):1069–77. doi:10.3109/02713683.2011.607536
   PubMed Web of Science ®Google Scholar
• Domènech EB, Marfany G. 2020. The relevance of oxidative stress in the pathogenesis and therapy of retinal dystrophies. Antioxidants. 9(4):347. doi:10.3390/antiox9040347
   Web of Science ®Google Scholar
• Chew S, Lampinen R, Saveleva L, Korhonen P, Mikhailov N, Grubman A, Polo JM, Wilson T, Komppula M, Rönkkö T, et al. Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells. Part Fibre Toxicol. 2020;17(1):18. doi:10.1186/s12989-020-00352-4.
   PubMed Web of Science ®Google Scholar
• Godley BF, Shamsi FA, Liang FQ, Jarrett SG, Davies S, Boulton M. 2005. Blue light induces mitochondrial DNA damage and free radical production in epithelial cells. J Biol Chem. 280(22):21061–66. doi:10.1074/jbc.M502194200
   PubMed Web of Science ®Google Scholar
• Bertram KM, Baglole CJ, Phipps RP, Libby RT. 2009. Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration. Am J Physiol - Cell Physiol. 297(5):C1200–10. doi:10.1152/ajpcell.00126.2009
   PubMed Web of Science ®Google Scholar
• Chance B, Schoener B, Oshino R, Itshak F, Nakase Y. Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals. J Biol Chem. 1979;254(11):4764–71. doi:10.1016/S0021-9258(17)30079-0.
   PubMed Web of Science ®Google Scholar
• Benson RC, Meyer RA, Zaruba ME, McKhann GM. Cellular autofluorescence–is it due to flavins? J Histochem Cytochem off J Histochem Soc. 1979;27(1):44–48. doi:10.1177/27.1.438504
   PubMed Web of Science ®Google Scholar
• Field MG, Yang D, Bian ZM, Petty HR, Elner VM. 2011. Retinal flavoprotein fluorescence correlates with mitochondrial stress, apoptosis, and chemokine expression. Exp Eye Res. 93(4):548–55. doi:10.1016/j.exer.2011.06.023
   PubMed Web of Science ®Google Scholar
• Andrade Romo JS, Lynch G, Liu K, Kim D, Jansen M, Field MG, Elner VM, Rosen RB. Flavoprotein fluorescence correlation with visual acuity response in patients receiving anti-VEGF injection for diabetic macular edema. Oxid Med Cell Longev. 2018;2018:e3567306. doi:10.1155/2018/3567306.
   PubMed Web of Science ®Google Scholar
• Field MG, Elner VM, Park S, Hackel R, Heckenlively JR, Elner SG, Petty HR. Detection of retinal metabolic stress due to central serous retinopathy. Retina Phila Pa. 2009;29(8):1162–66. doi:10.1097/IAE.0b013e3181a3b923.
   PubMed Web of Science ®Google Scholar
• Field MG, Elner VM, Puro DG, Feuerman JM, Musch DC, Pop-Busui R, Hackel R, Heckenlively JR, Petty HR. Rapid, noninvasive detection of diabetes-induced retinal metabolic stress. Arch Ophthalmol Chic Ill 1960. 2008;126(7):934–38. doi:10.1001/archopht.126.7.934.
   PubMedGoogle Scholar
• Elner SG, Elner VM, Field MG, Park S, Heckenlively JR, Petty HR. Retinal flavoprotein autofluorescence as a measure of retinal health. Trans Am Ophthalmol Soc. 2008;106:215–22. discussion 222-224.
   PubMedGoogle Scholar
• Elner VM, Park S, Cornblath W, Hackel R, Petty HR. 2008. Flavoprotein autofluorescence detection of early ocular dysfunction. Arch Ophthalmol Chic Ill 1960. 126(2):259–60. doi:10.1001/archophthalmol.2007.44
   PubMedGoogle Scholar
• Zhou DB, Castanos MV, Geyman L, Rich CA, Tantraworasin A, Ritch R, Rosen RB. Mitochondrial dysfunction in primary open-angle glaucoma characterized by flavoprotein fluorescence at the optic nerve head. Ophthalmol Glaucoma. Published online 2021 Dec 27;5: S2589-4196(21)00285-4. doi:10.1016/j.ogla.2021.12.006
   PubMedGoogle Scholar
• Safety of laser products—part 1: equipment classification and requirements. Geneva Int Tech Comm. 2007: IEC 60825-1.
   Google Scholar
• Chen AX, Conti TF, Hom GL, Greenlee TE, Raimondi R, Briskin IN, Rich CA, Kampani R, Engel R, Sharma S, et al. Functional imaging of mitochondria in retinal diseases using flavoprotein fluorescence. Eye. 2021;35(1):74–92. doi:10.1038/s41433-020-1110-y.
   PubMed Web of Science ®Google Scholar
• Gregori NZ, Feuer W, Rosenfeld PJ. Novel method for analyzing Snellen visual acuity measurements. Retina Phila Pa. 2010;30(7):1046–50. doi:10.1097/IAE.0b013e3181d87e04.
   PubMed Web of Science ®Google Scholar
• Jadeja RN, Martin PM. Oxidative stress and inflammation in retinal degeneration. Antioxidants. 2021;10(5):790. doi:10.3390/antiox10050790.
   Web of Science ®Google Scholar
• Trachsel-Moncho L, Benlloch-Navarro S, Fernández-Carbonell Á, Ramírez-Lamelas DT, Olivar T, Silvestre D, Poch E, Miranda M. Oxidative stress and autophagy-related changes during retinal degeneration and development. Cell Death Dis. 2018;9(8):1–12. doi:10.1038/s41419-018-0855-8.
   PubMedGoogle Scholar
• Pia S, Lui F Melas syndrome. StatPearls. StatPearls Publishing; 2022. [accessed 2022 Jan 18]. http://www.ncbi.nlm.nih.gov/books/NBK532959/
   Google Scholar
• Scaglia F, Northrop JL. 2006. The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options. CNS Drugs. 20(6):443–64. doi:10.2165/00023210-200620060-00002
   PubMed Web of Science ®Google Scholar
• Daruich A, Matet A, Borruat FX. 2014. Macular dystrophy associated with the mitochondrial DNA A3243G mutation: pericentral pigment deposits or atrophy? Report of two cases and review of the literature. BMC Ophthalmol. 14(1):77. doi:10.1186/1471-2415-14-77
   PubMedGoogle Scholar
• Glatz C, D’Aco K, Smith S, Sondheimer N. Mutation in the mitochondrial tRNAVal causes mitochondrial encephalopathy, lactic acidosis and stroke-like episodes. Mitochondrion. 2011;11(4):615–19. doi:10.1016/j.mito.2011.04.003.
   PubMed Web of Science ®Google Scholar
• Lima LH, Cella W, Greenstein VC, Wang NK, Busuioc M, Smith RT, Yannuzzi LA, Tsang SH. Structural assessment of hyperautofluorescent ring in patients with retinitis pigmentosa. Retina Phila Pa. 2009;29(7):1025–31. doi:10.1097/IAE.0b013e3181ac2418.
   PubMed Web of Science ®Google Scholar
• Boon CJF, Jeroen Klevering B, Keunen JEE, Hoyng CB, Theelen T. 2008. Fundus autofluorescence imaging of retinal dystrophies. Vision Res. 48(26):2569–77. doi:10.1016/j.visres.2008.01.010
   PubMed Web of Science ®Google Scholar
• Pichi F, Abboud EB, Ghazi NG, Khan AO. 2018. Fundus autofluorescence imaging in hereditary retinal diseases. Acta Ophthalmol (Copenh). 96(5):e549–61. doi:10.1111/aos.13602
   Web of Science ®Google Scholar
• Yung M, Klufas MA, Sarraf D. 2016. Clinical applications of fundus autofluorescence in retinal disease. Int J Retina Vitr. 2(1):12. doi:10.1186/s40942-016-0035-x
   PubMedGoogle Scholar
• Lenis TL, Hu J, Ng SY, Jiang Z, Sarfare S, Lloyd MB, Esposito NJ, Samuel W, Jaworski C, Bok D, et al. Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration. Proc Natl Acad Sci U S A. 2018;115(47):E11120–27. doi:10.1073/pnas.1802519115.
   PubMed Web of Science ®Google Scholar