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Research Article

Association of VEGF Gene Polymorphisms with Diabetic Retinopathy in a South Indian Cohort

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Pages 11-15 | Received 20 Jun 2007, Accepted 03 Sep 2007, Published online: 08 Jul 2009

REFERENCES

  • Aiello L P, Avery R L, Arrigg P G, Keyt B A, Jampel H D, Shah S T, Pasquale L R, Thieme H, Iwamoto M A, Park J E, Nguyen H V, Ferrara H V, King G L. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med. 1994; 331: 1519–1520
  • Poulaki V, Joussen A M, Mitsiades N, Mitsiades C S, Iliaki E F, Adamis A P. Insulin-Like Growth Factor-I plays a pathogenetic role in diabetic retinopathy. Am J Pathol. 2004; 165: 457–469
  • Lu M, Kuroki M, Amano S, Tolentino M, Keough K, Kim I, Bucala R, Adamis A P. Advanced glycation end products increase retinal vascular endothelial growth factor expression. J Clin Invest 1998; 101(6)1219–1224
  • Chiarelli F, Santilli F, Mohn A. role of growth factors in the development of diabetic complications. Horm Res. 2000; 53: 53–67
  • Ogata N, Nishikawa M, Nishimura T, Mitsuma Y, Matsumura M. Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy. Am J Ophthal. 2002; 134: 348–353
  • Tischer E, Mitchell R, Hartman T, Silva M, Gospodarowicz D, Fiddes J C, Abraham J A. The human gene for vascular endothelial growth factor: multiple protein forms are encoded through alternative exon splicing. J Biol Chem. 1991; 266: 11947–11954
  • Renner W, Kotschan S, Hoffmann C, Obermayer-Pietsch B, Pilger E. A Common 936 C/T Mutation in the gene for vascular endothelial growth factor is associated with vascular endothelial growth factor plasma levels. J Vasc Res. 2000; 37: 443–448
  • Lambrechts D, Storkebaum E, Morimoto M, Del-Favero J, Desmet F, Marklund S L, Wyns S, Thijs V, Andersson J, van Marion I, Al-Chalabi A, Bornes S, et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motorneurons against ischemic death. Nat. Genet. 2003; 34: 383–394
  • Lambrechts D, Devriendt K, Driscoll D A, Goldmuntz E, Gewillig M, Vlietinck R, Collen D, Carmeliet P. Low expression VEGF haplotype increases the risk for tetralogy of Fallot: a family based association study (Letter). J Med Genet. 2005; 42: 519–522
  • Howell W M, Ali S, Rose-Zerilli M J, Ye S. VEGF polymorphisms and severity of atherosclerosis. J Med Genet. 2005; 42: 485–490
  • Del Bo R, Scarlato M, Ghezzi S, Martinelli Boneschi F, Fenoglio C, Galbiati S, Virgilio R, Galimberti D, Galimberti G, Crimi M, Ferrarese C, Scarpini E, Bresolin N, Comi G P. Vascular endothelial growth factor gene variability is associated with increased risk for AD. Ann Neurol. 2005; 57: 373–380
  • Jacobs E J, Feigelson H S, Bain E B, Brady K A, Rodriguez C, Stevens V L, Patel A V, Thun M J, Calle E E. Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort. Breast Cancer Res 2006; 8(2)R22, Epub 2006 Apr 13
  • Vannay A, Dunai G, Bányász I, Szabó M, Vámos R, Treszl A, Hajdú J, Tulassay T, Vásárhelyi B. Association of genetic polymorphisms of vascular endothelial growth factor and risk for proliferative retinopathy of prematurity. Paediatric Res 2005; 57(3)396–398
  • Awata T, Inoue K, Kurihara S, Ohkubo T, Watanabe M, Inukai K, Inoue I, Katayama S. A common polymorphism in the 5-prime-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes. Diabetes 2002; 51: 1635–1639
  • Suganthalakshmi B, Anand R, Kim R, Mahalakshmi R, Karthikprakash S, Namperumalsamy P. Association of VEGF eNOS gene polymorphisms in type 2 diabetic retinopathy. Mol Vis. 2006; 12: 336–341
  • Rani P K, Raman R, Agarwal S, Paul P G, Uthra S, Margabandhu G, et al. Diabetic retinopathy screening model for rural population: Awareness and screening methodology. Rural Remote Health 2005; 5(4)350
  • Agarwal S, Raman R, Paul P G, Rani P K, Uthra S, Gayathree R, et al. Sankara Nethralaya-Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS 1): Study design and research methodology. Ophthalmic Epidemiol 2005; 12(2)143–153
  • Klein R, Klein B EK, Magli Y L, Brothers R J, Meuer S M, Moss S E, et al. An alternative method of grading diabetic retinopathy. Ophthalmology. 1986; 93: 1183–1187
  • Flanagin A. Who wrote the Declaration of Helsinki?. JAMA 1997; 277: 926
  • Wolff R, Gemmil R. Purifying and Analysing Genomic DNA. Genome Analysis: A Laboratory Manual. Vol. 4, B Bruce, E D Green, P Hieter, S Klaplholz, R M Myeres, H Riethman. Cold Spring Harbour Laboratory Press, New York 1998; 1–82
  • Ray D, Mishra M, Ralph S, Read Davies R, Brenchley P. Association of the VEGF gene with proliferative diabetic retinopathy but not proteinuria in diabetes. Diabetes 2004; 53: 861–864
  • Awata T, Kurihara S, Takata N, Neda T, Iizuka H, Ohkubo T, Osaki M, Watanabe M, Nakashima Y, Inukai K, Inoue I, Kawasaki I, Mori K, Yoneya S, Katayama S. Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes. Biochem Biophys Res Commun 2005; 333: 679–685

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