Polymeric micelles: authoritative aspects for drug delivery

References

• Zana , R . 2005 . “ Introduction to surfactants and surfactant self-assemblies ” . In Dynamics of surfactant self-assemblies – micelles, microemulsions, vesicles, and lyotropic phases , Edited by: Zana , R . 2 – 36 . Boca Raton , FL : Taylor & Francis .
   Google Scholar
• Rangel-Yagui , CO , Pessoa , JA and Tavares , LC . 2005 . Micellar solubilization of drugs . Journal of Pharmacy and Pharmaceutical Sciences , 8 : 147 – 163 .
   PubMed Web of Science ®Google Scholar
• Adams , ML , Lavasanifar , A and Kwon , GS . 2003 . Amphiphilic block copolymers for drug delivery . Journal of Pharmaceutical Sciences , 92 : 1343 – 1355 .
   PubMed Web of Science ®Google Scholar
• M. Malmsten, Micelles. In: Surfactants and Polymers in Drug Delivery. Marcel Dekker, New York (2002).19–50.
   Google Scholar
• Y. Moroi, Dissolution of amphiphiles. In: Micelles: Theoretical and Applied Aspects, Plenum Press, New York (1992).25–40.
   Google Scholar
• Hickok , RS , Wedge , SA , Hansen , AL , Morris , KF , Billiot , FH and Warner , IM . 2002 . Pulsed field gradient NMR investigation of solubilization equilibria in amino acid and dipeptide terminated micellar and polymeric surfactant solutions . Magnetic Resonance in Chemistry , 40 : 755 – 761 .
   Google Scholar
• Jones , MC and Leroux , JC . 1999 . Polymeric micelles a new generation of colloidal drug carriers . European Journal of Pharmaceutics and Biopharmaceutics , 48 : 101 – 111 .
   PubMed Web of Science ®Google Scholar
• Trubetskoy , VS and Torchilin , VP . 1996 . Polyethyleneglycol-based micelles as carriers for delivery of therapeutic and diagnostic agents . STP Pharma Sciences , 6 : 79 – 86 .
   Google Scholar
• Zarafshani , Z , Akdemir , O and Lutz , JF . 2008 . A ‘‘click’’ strategy for tuning in situ the hydrophilic-hydrophobic balance of AB macrosurfactants . Macromolecular Rapid Communications , 29 : 1161 – 1166 .
   Web of Science ®Google Scholar
• Erhardt , R , Boker , A , Zettl , H , Kaya , H , Pyckhout-Hintzen , W , Krausch , G , Abetz , V and Muller , AHE . 2001 . Janus micelles . Macromolecules , 34 : 1069 – 1075 .
   Web of Science ®Google Scholar
• Forster , S and Plantenberg , T . 2002 . From self-organizing polymers to nanohybrid and biomaterials . Angewandte Chemie International Edition , 41 : 688 – 714 .
   Web of Science ®Google Scholar
• Jacquin , M , Muller , P , Cottet , H , Crooks , R and Theodoly , O . 2007 . Controlling the melting of kinetically frozen poly(butyl acrylate-b-acrylic acid) micelles via addition of surfactant . Langmuir , 23 : 9939 – 9948 .
   PubMed Web of Science ®Google Scholar
• Cao , Y and Li , H . 2003 . Micellar solutions of CMC amphipathic copolymers . Polymer International , 52 : 869 – 875 .
   Google Scholar
• Lutz , JF , Pfeifer , S and Zarafshani , Z . 2007 . In situ functionalization of thermoresponsive polymeric micelles using the “click” cycloaddition of azides and alkynes . QSAR & Combinatorial Science , 26 : 1151 – 1158 .
   Google Scholar
• Liu , H , Xu , J , Jiang , J , Yin , J , Narain , R , Cai , Y and Liu , S . 2007 . Syntheses and micellar properties of well-defined amphiphilic AB2 and A2B Y-shaped miktoarm star copolymers of ϵ-caprolactone and 2-(dimethylamino)ethyl methacrylate . Journal of Polymer Science Part A: Polymer Chemistry , 45 : 1446 – 1462 .
   Google Scholar
• Zhang , YX , Liu , SP , Du , LB , Zhang , DQ , Chen , JY and Jiang , M . 2002 . Synthesis and characterization of fluorocarbon-containing, hydrophobically associative poly (acrylic acid-co-Rf-poly (ethylene glycol) macromonomer) . Journal of Applied Polymer Science , 84 : 1035 – 1047 .
   Google Scholar
• Kline , SR . 1999 . Polymerization of rodlike micelles . Langmuir , 15 : 2726 – 2732 .
   Web of Science ®Google Scholar
• Miyata , K , Christie , RJ and Kataoka , K . 2011 . Polymeric micelles for nano-scale drug delivery . Reactive & Functional Polymers , 71 : 227 – 234 .
   Web of Science ®Google Scholar
• Mourya , VK , Inamdar , NN , Nawale , RB and Kulthe , SS . 2011 . Polymeric micelles: general considerations and their applications . Indian Journal of Pharmaceutical Education and Research , 45 : 128 – 138 .
   Web of Science ®Google Scholar
• Varma , MV and Panchagnula , RV . 2005 . Enhanced oral paclitaxel absorption with vitamin E-TPGS: effect on solubility and permeability in vitro, in situ and in vivo . European Journal of Pharmaceutical Sciences , 25 : 445 – 453 .
   PubMed Web of Science ®Google Scholar
• Bromberg , L . 2008 . Polymeric micelles in oral chemotherapy . Journal of Controlled Release , 128 : 99 – 112 .
   PubMed Web of Science ®Google Scholar
• Kabanov AV, Alakhov VY. Micelles of amphiphilic block copolymers as vehicles for drug delivery. In: Amphiphilic block copolymers: self-assembly and applications. Alexandris P, Lindman B, editors. Amsterdam: Elsevier Science; 2000. 352–376.
   Google Scholar
• Elsabahy , M , Perron , M , Bertrand , N , Yu , G and Leroux , JC . 2007 . Solubilization of docetaxel in poly(ethylene oxide)-block-poly(butylene/styrene oxide) micelles . Biomacromolecules , 8 : 2250 – 2257 .
   PubMed Web of Science ®Google Scholar
• Peng , X and Zhang , L . 2007 . Formation and morphologies of novel self-assembled micelles from chitosan derivatives . Langmuir , 23 : 10493 – 10498 .
   PubMed Web of Science ®Google Scholar
• Yokoyama , M . 1998 . “ Novel passive targetable drug delivery with polymeric micelles ” . In Biorelated polymers and gels: controlled release and applications in biomedical engineering , Edited by: Okano , T . 193 – 231 . San Diego , CA : Academic Press .
   Google Scholar
• Zhang , C , Qu , G , Sun , Y , Wu , BX , Yao , Z , Guo , Q , Ding , Q , Yuan , S , Shen , Z , Ping , Q and Zhou , H . 2008 . Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel . Biomaterials , 29 : 1233 – 1241 .
   PubMed Web of Science ®Google Scholar
• Nishiyama , N , Okazaki , S , Cabral , H , Miyamoto , M , Kato , Y , Sugiyama , Y , Nishio , K , Matsumura , Y and Kataoka , K . 2003 . Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice . Cancer Research , 63 : 8977 – 8983 .
   PubMed Web of Science ®Google Scholar
• Jiang , M , Wu , Y , Heb , Y and Nie , J . 2009 . Micelles formed by self-assembly of hyperbranched poly[(amine-ester)-co-(D, L-lactide)] (HPAE-co-PLA) copolymers for protein drug delivery . Polymer International , 58 : 31 – 39 .
   Web of Science ®Google Scholar
• Mahmud , A , Xiong , XB , Aliabadi , HM and Lavasanifar , A . 2007 . Polymeric micelles for drug targeting . Journal of Drug Targeting , 15 : 553 – 584 .
   PubMed Web of Science ®Google Scholar
• Kwon , GS and Okano , T . 1996 . Polymeric micelles as new drug carriers . Advanced Drug Delivery Reviews , 21 : 107 – 116 .
   Web of Science ®Google Scholar
• Harada , A and Kataoka , K . 1995 . Block copolymer micelles as long-circulating drug vehicles . Advanced Drug Delivery Reviews , 16 : 295 – 309 .
   Google Scholar
• Harada , A and Kataoka , K . 1995 . Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly(ethylene glycol) segments . Macromolecules , 28 : 5294 – 5299 .
   Web of Science ®Google Scholar
• Scholz , C , Iijima , M , Nagasaki , Y and Kataoka , K . 1995 . A novel reactive polymeric micelle with aldehyde groups on its surface . Macromolecules , 28 : 7295 – 7297 .
   Web of Science ®Google Scholar
• Juillerat-Jeanneret , L and Schmitt , F . 2007 . Chemical modification of therapeutic drugs or drug vector systems to achieve targeted therapy: Looking for the grail . Medicinal Research Reviews , 27 : 574 – 590 .
   PubMed Web of Science ®Google Scholar
• Kataoka , K , Harada , A and Nagasaki , Y . 2001 . Block copolymer micelles for drug delivery: Design, characterization and biological significance . Advanced Drug Delivery Reviews , 47 : 113 – 131 .
   PubMed Web of Science ®Google Scholar
• Torchilin , VP . 2004 . Targeted polymeric micelles for delivery of poorly soluble drugs . Cellular and Molecular Life Sciences , 61 : 2549 – 2559 .
   PubMed Web of Science ®Google Scholar
• Seo , DH , Jeong , Y , Kim , DG , Jang , MJ , Jang , MK and Nah , JW . 2009 . Methotrexate-incorporated polymeric nanoparticles of methoxy poly(ethylene glycol)-grafted chitosan . Colloids and Surfaces B: Biointerfaces , 69 : 157 – 163 .
   PubMed Web of Science ®Google Scholar
• Jiang , GB , Quan , D , Liao , K and Wang , H . 2006 . Novel polymer micelles prepared from chitosan grafted hydrophobic palmitoyl groups for drug delivery . Molecular Pharmaceutics , 3 : 152 – 160 .
   PubMed Web of Science ®Google Scholar
• Fournier , E , Dufresne , MH , Smith , DC , Ranger , M and Leroux , JC . 2004 . A novel one-step drug-loading procedure for water-soluble amphiphilic nanocarriers . Pharmaceutical Research , 21 : 962 – 968 .
   PubMed Web of Science ®Google Scholar
• Kwon , GS , Naito , M , Yokoyama , M , Okano , T , Sakurai , Y and Kataoka , K . 1995 . Physical entrapment of adriamicin in AB block copolymer micelles . Pharmaceutical Research , 12 : 192 – 195 .
   PubMed Web of Science ®Google Scholar
• La , SB , Okano , T and Kataoka , K . 1996 . Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(β-benzyl l-aspartate) block copolymer micelles . Journal of Pharmaceutical Sciences , 85 : 85 – 90 .
   PubMed Web of Science ®Google Scholar
• Ye , YQ , Yang , FL , Hu , FQ , Du , YZ , Yuan , H and Yu , HY . 2008 . Core-modified chitosan-based polymeric micelles for controlled release of doxorubicin . International Journal of Pharmaceutics , 352 : 294 – 301 .
   PubMed Web of Science ®Google Scholar
• Hu , FQ , Wu , XL , Du , YZ , You , J and Yuan , H . 2008 . Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin . European Journal of Pharmaceutics and Biopharmaceutics , 69 : 117 – 125 .
   PubMed Web of Science ®Google Scholar
• Yang , ZL , Li , XR , Yang , KW and Liu , Y . 2008 . Amphotericin B-loaded poly(ethylene glycol)-poly(lactide) micelles: Preparation, freeze-drying, and in vitro release . Journal of Biomedical Materials Research , 85A : 539 – 546 .
   Google Scholar
• Huh , KM , Lee , SC and Cho , YW . 2005 . Hydrotropic polymer micelle system for delivery of paclitaxel . Journal of Controlled Release , 101 : 59 – 68 .
   PubMed Web of Science ®Google Scholar
• Burkersroda , FV , Gref , R and Gopferich , A . 1997 . Erosion of biodegradable block copolymers made of poly(DL-lactic acid) and poly(ethylene glycol) . Biomaterials , 18 : 1599 – 1607 .
   PubMedGoogle Scholar
• Hamley , IW . 2004 . “ Introduction to block polymers ” . In Developments in block copolymer science and technology , Edited by: Hamley , IW . 1 – 30 . Chichester : Wiley .
   Google Scholar
• Erdogan , T , Bernaerts , KV , Van Renterghem , LM , Du Prez , FE and Goethals , EJ . 2005 . Preparation of star block co-polymers by combination of cationic ring opening polymerization and atom transfer radical polymerization . Designed Monomers and Polymers , 8 : 705 – 714 .
   Web of Science ®Google Scholar
• Zhou , J , Wang , L and Ma , J . 2009 . Recent research progress in the synthesis and properties of amphiphilic block co-polymers and their applications in emulsion polymerization . Designed Monomers and Polymers , 12 : 19 – 41 .
   Web of Science ®Google Scholar
• Maniruzzaman , M , Kawaguchi , S and Ito , K . 2000 . Micellar copolymerization of styrene with a poly(ethylene oxide) macromonomer in water to a unimolecular graft copolymer micelle . Designed Monomers and Polymers , 3 : 255 – 261 .
   Web of Science ®Google Scholar
• Guo , Z and Fang , Z . 2009 . Effects of the competition between grafting reaction and decomposition on the miscibility and rheological behaviors of PS/POE blends in the presence of AlCl3 . Polymer-Plastics Technology and Engineering , 48 : 1185 – 1190 .
   Web of Science ®Google Scholar
• Lu , HW , Zhang , LM , Wang , C and Chen , RF . 2011 . Preparation and properties of new micellar drug carriers based on hydrophobically modified amylopectin . Carbohydrate Polymers , 83 : 1499 – 1506 .
   Google Scholar
• Bronstein , LM , Chernyshov , DM , Timofeeva , GI , Dubrovina , LV , Valetsky , PM and Khokhlov , AR . 2000 . Interaction of polystyrene-block-poly(ethylene oxide) micelles with cationic surfactant in aqueous solutions. Metal colloid formation in hybrid systems . Langmuir , 16 : 3626 – 3632 .
   Web of Science ®Google Scholar
• Michels , B , Waton , G and Zana , R . 1997 . Dynamics of micelles of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymers in aqueous solutions . Langmuir , 13 : 3111 – 3118 .
   Web of Science ®Google Scholar
• Oh , KT and Lee , ES . 2008 . Cancer-associated pH-responsive tetracopolymeric micelles composed of poly(ethylene glycol)-b-poly(L-histidine)- b-poly(L-lactic acid)-b-poly(ethylene glycol) . Polymers for Advanced Technologies , 19 : 1907 – 1913 .
   Web of Science ®Google Scholar
• Hadjiantoniou , NA , Christoforou , TK , Loizou , E , Porcar , L and Patrickios , CS . 2010 . Alternating amphiphilic multiblock copolymers: Controlled synthesis via raft polymerization and aqueous solution characterization . Macromolecules , 43 : 2713 – 2720 .
   Google Scholar
• Wei , H , Zhang , XZ , Chen , WQ , Cheng , SX and Zhuo , RX . 2007 . Self-assembled thermosensitive micelles based on poly(L-lactide-star block-N-isopropylacrylamide) for drug delivery . Journal of Biomedical Materials Research , 83A : 980 – 989 .
   Google Scholar
• Fattahi , A , Golozar , MA , Varshosaz , J , Sadeghi , HM and Fathi , M . 2012 . Preparation and characterization of micelles of oligomeric chitosan linked to all-trans retinoic acid . Carbohydrate Polymers , 87 : 1176 – 1184 .
   Web of Science ®Google Scholar
• Li , Y , Zhang , S , Meng , X , Chen , X and Ren , G . 2011 . The preparation and characterization of a novel amphiphilic oleoyl-carboxymethyl chitosan self-assembled nanoparticles . Carbohydrate Polymers , 83 : 130 – 136 .
   Web of Science ®Google Scholar
• Chen , XG , Lee , CM and Park , HJ . 2003 . O/W emulsification for the self-aggregation and nanoparticle formation of linoleic acid modified chitosan in the aqueous system . Journal of Agriculture and Food Chemistry , 51 : 3135 – 3139 .
   PubMed Web of Science ®Google Scholar
• Zhang , C , Ding , Y , Ping , Q and Yu , L . 2006 . Novel chitosan-derived nanomaterials and their micelle-forming properties . Journal of Agriculture and Food Chemistry , 54 : 8409 – 8416 .
   PubMed Web of Science ®Google Scholar
• Tan , YL and Liu , CG . 2009 . Self-aggregated nanoparticles from linoleic acid modified carboxymethyl chitosan: Synthesis, characterization and application in vitro . Colloids and Surfaces B: Biointerfaces , 69 : 178 – 182 .
   PubMed Web of Science ®Google Scholar
• Huo , M , Zhang , Y , Zhou , J , Zou , A and Li , J . 2011 . Formation, microstructure, biodistribution and absence of toxicity of polymeric micelles formed by N-octyl-N,O-carboxymethyl chitosan . Carbohydrate Polymers , 83 : 1959 – 1969 .
   Web of Science ®Google Scholar
• Duan , K , Zhang , X , Tang , X , Yu , J , Liu , S , Wang , D , Li , Y and Huang , J . 2010 . Fabrication of cationic nanomicelle from chitosan-graft-polycaprolactone as the carrier of 7-ethyl-10-hydroxy-camptothecin . Colloids and Surfaces B: Biointerfaces , 76 : 475 – 482 .
   PubMed Web of Science ®Google Scholar
• Hu , FQ , Liu , LN , Du , YZ and Yuan , H . 2009 . Synthesis and antitumor activity of doxorubicin conjugated stearic acid-g-chitosan oligosaccharide polymeric micelles . Biomaterials , 30 : 6955 – 6963 .
   PubMed Web of Science ®Google Scholar
• Qu , G , Yao , Z , Zhang , C , Wu , X and Ping , Q . 2009 . PEG conjugated N-octyl-O-sulfate chitosan micelles for delivery of paclitaxel: In vitro characterization and in vivo evaluation . European Journal of Pharmaceutical Sciences , 37 : 98 – 105 .
   PubMed Web of Science ®Google Scholar
• Nakayama , M and Okano , T . 2005 . Polymer terminal group effects on properties of thermoresponsive polymeric micelles with controlled outer-shell chain lengths . Biomacromolecules , 6 : 2320 – 2327 .
   PubMed Web of Science ®Google Scholar
• Kriz , J , Pletil , J , Tuzar , Z , Pospisil , H , Brus , J , Jakes , J , Masar , B , Vlcek , P and Doskocilova , D . 1999 . Interface affected polymer dynamics: NMR, SANS, and DLS study of the influence of shell-core interactions on the core chain mobility of poly(2-ethylhexyl acrylate)-block-poly(acrylic acid) micelles in water . Macromolecules , 32 : 397 – 410 .
   Google Scholar
• Prochazka , K , Martin , TJ , Munk , P and Webber , SE . 1996 . Polyelectrolyte poly(tert-butyl acrylate)-block-poly(2-vinylpyridine) micelles in aqueous media . Macromolecules , 29 : 6518 – 6525 .
   Web of Science ®Google Scholar
• Colombani , O , Ruppel , M , Burkhardt , M and Drechsler , M . 2007 . Structure of micelles of poly(n-butyl acrylate)-block-poly(acrylic acid) diblock copolymers in aqueous solution . Macromolecules , 40 : 4351 – 4362 .
   Web of Science ®Google Scholar
• Kriz , J , Masar , B , Pletil , J , Tuzar , Z , Pospisil , H and Doskocilova , D . 1998 . Three-layer micelles of an ABC block copolymer: NMR, SANS, and LS study of a poly(2-ethylhexyl acrylate)-block-poly(methyl methacrylate)-block-poly(acrylic acid) copolymer in D2O . Macromolecules , 31 : 41 – 51 .
   Web of Science ®Google Scholar
• Liu , S , Weaver , JVM , Tang , Y , Billingham , NC , Armes , SP and Tribe , K . 2002 . Synthesis of shell cross-linked micelles with pH-responsive cores using ABC triblock copolymers . Macromolecules , 35 : 6121 – 6131 .
   Google Scholar
• Geng , Y and Discher , DE . 2005 . Hydrolytic degradation of poly(ethylene oxide)-block-polycaprolactone worm micelles . Journal of the American Chemical Society , 127 : 12780 – 12781 .
   PubMed Web of Science ®Google Scholar
• Soo , PL , Luo , L , Maysinger , D and Eisenberg , A . 2002 . Incorporation and release of hydrophobic probes in biocompatible polycaprolactone-block-poly(ethylene oxide) micelles: Implications for drug delivery . Langmuir , 18 : 9996 – 10004 .
   Web of Science ®Google Scholar
• Soo , PL , Lovric , J , Davidson , P , Maysinger , D and Eisenberg , A . 2005 . Polycaprolactone-block-poly(ethylene oxide) micelles: A nanodelivery system for 17β-estradiol . Molecular Pharmaceutics , 2 : 519 – 527 .
   PubMedGoogle Scholar
• Allen , C , Yu , Y , Maysinger , D and Eisenberg , A . 1998 . Polycaprolactone-b-poly(ethylene oxide) block copolymer micelles as a novel drug delivery vehicle for neurotrophic agents FK506 and L-685,818 . Bioconjugate Chemistry , 9 : 564 – 572 .
   PubMed Web of Science ®Google Scholar
• Hu , Y , Zhang , L , Cao , Y , Ge , H , Jiang , X and Yang , C . 2004 . Degradation behavior of poly(ϵ-caprolactone)-b-poly(ethylene glycol)-b-poly(ϵ-caprolactone) micelles in aqueous solution . Biomacromolecules , 5 : 1756 – 1762 .
   PubMed Web of Science ®Google Scholar
• Gong , CY , Shi , S , Dong , PW , Kan , B , Gou , ML , Wang , XH , Li , XY , Luo , F , Zhao , X , Wei , YQ and Qian , ZY . 2009 . Synthesis and characterization of PEG-PCL-PEG thermosensitive hydrogel . International Journal of Pharmaceutics , 365 : 89 – 99 .
   PubMed Web of Science ®Google Scholar
• Lee , SC , Kim , KJ , Jeong , YK , Chang , JH and Choi , J . 2005 . pH-induced reversible complexation of poly(ethylene glycol) and poly(ϵ-caprolactone)-b-poly(methacrylic acid) copolymer micelles . Macromolecules , 38 : 9291 – 9297 .
   Web of Science ®Google Scholar
• Wang , YC , Liu , XQ , Sun , TM , Xiong , MH and Wang , J . 2008 . Functionalized micelles from block copolymer of polyphosphoester and poly(ϵ-caprolactone) for receptor-mediated drug delivery . Journal of Controlled Release , 128 : 32 – 40 .
   PubMed Web of Science ®Google Scholar
• Zhou , J , Wang , L , Ma , J , Wang , J , Yu , H and Xiao , A . 2010 . Temperature- and pH-responsive star amphiphilic block copolymer prepared by a combining strategy of ring-opening polymerization and reversible addition- fragmentation transfer polymerization . European Polymer Journal , 46 : 1288 – 1298 .
   Web of Science ®Google Scholar
• Huang , Y , Li , L and Fang , Y . 2010 . Self-assembled particles of N-phthaloylchitosan-g-polycaprolactone molecular bottle brushes as carriers for controlled release of indometacin . Journal of Materials Science: Materials in Medicine , 21 : 557 – 565 .
   PubMedGoogle Scholar
• Danhier , F , Magotteaux , N , Ucakar , B , Lecouturier , N , Brewster , M and Preat , V . 2009 . Novel self-assembling PEG-p-(CL-co-TMC) polymeric micelles as safe and effective delivery system for paclitaxel . European Journal of Pharmaceutics and Biopharmaceutics , 73 : 230 – 238 .
   PubMed Web of Science ®Google Scholar
• Yang , Z , Xie , J , Zhou , W and Shi , W . 2009 . Temperature sensitivity and drug encapsulation of star-shaped amphiphilic block copolymer based on dendritic poly(ether-amide) . Journal of Biomedical Materials Research , 89 : 988 – 1000 .
   Google Scholar
• Yasugi , K , Nakamura , T , Nagasaki , Y , Kato , M and Kataoka , K . 1999 . Sugar-installed polymer micelles: Synthesis and micellization of poly(ethylene glycol)-poly(d,l-lactide) block copolymers having sugar groups at the PEG chain end . Macromolecules , 32 : 8024 – 8032 .
   Web of Science ®Google Scholar
• Jule , E , Nagasaki , Y and Kataoka , K . 2002 . Surface plasmon resonance study on the interaction between lactose-installed poly(ethylene glycol)-poly(d,l-lactide) block copolymer micelles and lectins immobilized on a gold surface . Langmuir , 18 : 10334 – 10339 .
   Web of Science ®Google Scholar
• Arimura , H , Ohya , Y and Ouchi , T . 2004 . The formation of biodegradable polymeric micelles from newly synthesized poly(aspartic acid)-block-polylactide AB-type diblock copolymers . Macromolecular Rapid Communications , 25 : 743 – 747 .
   Google Scholar
• Stepaek , M , Uchman , M and Prochazka , K . 2009 . Self-assemblies formed by four-arm star copolymers with amphiphilic diblock arms in aqueous solutions . Polymer , 50 : 3638 – 3644 .
   Google Scholar
• Xun , W , Wang , HY , Li , ZY , Cheng , SX , Zhang , XZ and Zhuo , RX . 2011 . Self-assembled micelles of novel graft amphiphilic copolymers for drug controlled release . Colloids and Surfaces B: Biointerfaces , 85 : 86 – 91 .
   PubMed Web of Science ®Google Scholar
• Benahmed , A , Ranger , M and Leroux , JC . 2001 . Novel polymeric micelles based on the amphiphilic diblock copolymer poly(N-vinyl-2-pyrrolidone)-block-poly(D,L-lactide) . Pharmaceutical Research , 18 : 323 – 328 .
   PubMed Web of Science ®Google Scholar
• Yin , H and Bae , YH . 2009 . Physicochemical aspects of doxorubicin-loaded pH-sensitive polymeric micelle formulations from a mixture of poly(L-histidine)-b-poly(L-lactide)- b-poly(ethylene glycol) . European Journal of Pharmaceutics and Biopharmaceutics , 71 : 223 – 230 .
   PubMed Web of Science ®Google Scholar
• Huang , CK , Lo , CL , Chen , HH and Hsiue , GH . 2007 . Multifunctional micelles for cancer cell targeting, distribution imaging, and anticancer drug delivery . Advanced Functional Materials , 17 : 2291 – 2297 .
   Web of Science ®Google Scholar
• Bhattarai , N , Bhattarai , SR , Yi , HK , Lee , JC , Khil , MS , Hwang , PH and Kim , HY . 2003 . Novel polymeric micelles of amphiphilic triblock copolymer poly(p-dioxanone-co-L-lactide)-block-poly(ethylene glycol) . Pharmaceutical Research , 20 : 2021 – 2027 .
   PubMedGoogle Scholar
• Martinez-Castro , N , Zhang , M , Pergushov , DV and Müller , AHE . 2006 . Anionic polymerization of N,N-dimethylacrylamide with thienyllithium and synthesis of block co-polymers of isobutylene and N,N-dimethylacrylamide by site transformation of chain ends . Designed Monomers and Polymers , 9 : 63 – 79 .
   Web of Science ®Google Scholar
• Volpert , E , Selb , J and Candau , F . 1998 . Associating behaviour of polyacrylamides hydrophobically modified with dihexylacrylamide . Polymer , 39 : 1025 – 1033 .
   Web of Science ®Google Scholar
• Quanming , L , Guohua , J and Kangkang , T . 2010 . Dendrimers in drug-delivery applications . Designed Monomers and Polymers , 13 : 301 – 324 .
   Google Scholar
• Chang , Y and Kim , C . 2001 . Synthesis and Photophysical Characterization of Amphiphilic Dendritic–Linear–Dendritic Block Copolymers . Journal of Polymer Science Part A: Polymer Chemistry , 39 : 918 – 926 .
   Web of Science ®Google Scholar
• Namazi , H and Jafarirad , S . 2011 . Application of hybrid organic/inorganic dendritic ABA type triblock copolymers as new nanocarriers in drug delivery systems . International Journal of Polymeric Materials , 60 : 603 – 619 .
   Web of Science ®Google Scholar
• Gao , C and Yan , D . 2004 . Hyperbranched polymers: from synthesis to applications . Progress in Polymer Science , 29 : 183 – 275 .
   Web of Science ®Google Scholar
• Guohua , J , Wenxing , C and Wei , X . 2008 . Environmental-sensitive hyperbranched polymers as drug carriers . Designed Monomers and Polymers , 11 : 105 – 122 .
   Google Scholar
• Amin , A , Rehim , MA and Mohamed , H . 2008 . Modification of some hyperbranched polyols with oligo (ethyleneoxide) units on the way to new applications . Polymer-Plastics Technology and Engineering , 47 : 1250 – 1255 .
   Web of Science ®Google Scholar
• Xiao , Y , Hong , H , Javadi , A , Engle , JW , Xu , W , Yang , Y , Zhang , Y , Barnhart , TE , Cai , W and Gong , Shaoqin . 2012 . Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imaging . Biomaterials , 33 : 3071 – 3082 .
   PubMed Web of Science ®Google Scholar
• Yoshida , E . 2007 . TEM observation of nonamphiphilic copolymer micelles . Colloid and Polymer Science , 285 : 941 – 945 .
   Google Scholar
• Yoshida , E and Ohta , M . 2005 . Preparation of micelles having a UV absorbent at their coronas using a ’non-amphiphilic’ di-block co-polymer . Designed Monomers and Polymers , 8 : 501 – 513 .
   Web of Science ®Google Scholar
• Bates , FS and Fredrickson , GH . 1990 . Block copolymer thermodynamics: theory and experiment . Annual Review of Physical Chemistry , 41 : 525 – 557 .
   PubMed Web of Science ®Google Scholar
• Cao , T , Munk , P , Ramireddy , C , Tuzar , Z and Webber , SE . 1991 . Fluorescence studies of amphiphilic poly(methacrylic acid)-block-polystyrene-block-poly-(methacrylic acid) micelles . Macromolecules , 24 : 6300 – 6305 .
   Web of Science ®Google Scholar
• Tsunashima , Y , Hirata , M and Kawamata , Y . 1990 . Diffusion motions and microphase separation of styrene-butadiene diblock copolymer in solution. 1. Extremely dilute solution region . Macromolecules , 23 : 1089 – 1096 .
   Google Scholar
• Prochazka , K , Martin , TJ , Webber , SE and Munk , P . 1996 . Onion type micelles in aqueous media . Macromolecules , 29 : 6526 – 6530 .
   Web of Science ®Google Scholar
• Giacomelli , C and Borsali , R . 2006 . Morphology of poly(ethylene oxide)-block-polycaprolatone block copolymer micelles controlled via the preparation method . Macromolecular Symposium , 245–246 : 147 – 153 .
   Google Scholar
• Tian , M , Qin , A , Ramireddy , C , Webber , SE , Munk , P , Tuzar , Z and Prochazka , K . 1993 . Hybridization of block copolymer micelles . Langmuir , 9 : 1741 – 1748 .
   Web of Science ®Google Scholar
• Hirano , T , Klesse , W and Ringsdorf , H . 1979 . Polymeric derivatives of activated cyclophosphamide as drug delivery systems in anti-tumor chemotherapy- Pharmacologically active polymers . Macromolecular Chemistry and Physics , 180 : 1125 – 1131 .
   Web of Science ®Google Scholar
• Gros , L , Ringsdorf , H and Schupp , H . 1981 . Polymeric antitumor agents on a molecular and on a cellular level? . Angewandte Chemie (International Edition in English) , 20 : 305 – 325 .
   Google Scholar
• Yokoyama , M , Fukushima , S , Uehara , R , Okamoto , K , Kataoka , K , Sakurai , Y and Okano , T . 1998 . Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor . Journal of Controlled Release , 50 : 79 – 92 .
   PubMed Web of Science ®Google Scholar
• He , F , Li , SM , Vert , M and Zhuo , RX . 2003 . Enzyme-catalyzed polymerization and degradation of copolymers prepared from ϵ-caprolactone and poly(ethylene glycol) . Polymer , 44 : 5145 – 5151 .
   Web of Science ®Google Scholar
• Chen , HL , Bei , JZ and Wang , SG . 2000 . Hydrolytic degradation of polyester-polyether block copolymer based on polycaprolactone/poly(ethylene glycol)/polylactide . Polymers for Advanced Technologies , 11 : 180 – 184 .
   Google Scholar
• Allen , C , Maysinger , D and Eisenberg , A . 1999 . Nano-engineering block copolymer aggregates for drug delivery . Colloids and Surfaces B: Biointerfaces , 16 : 3 – 27 .
   Web of Science ®Google Scholar
• Bromberg , L and Magner , E . 1999 . Release of hydrophobic compounds from micellar solutions of hydrophobically modified polyelectrolytes . Langmuir , 15 : 6792 – 6798 .
   Google Scholar
• Patrick , LS , Laibin , L , Maysinger , D and Eisenberg , A . 2002 . Incorporation and release of hydrophobic probes in biocompatible polycaprolactone-block-poly(ethylene oxide) micelles: Implications for drug delivery . Langmuir , 18 : 9996 – 10004 .
   Google Scholar
• Aliabadi , HM , Elhasi , S , Mahmud , A , Gulamhusein , R , Mahdipoor , P and Lavasanifar , A . 2007 . Encapsulation of hydrophobic drugs in polymeric micelles through co-solvent evaporation: The effect of solvent composition on micellar properties and drug loading . International Journal of Pharmaceutics , 329 : 158 – 165 .
   PubMed Web of Science ®Google Scholar
• Gohy , JF . 2005 . Block copolymer micelles . Advances in Polymer Science , 190 : 65 – 136 .
   Web of Science ®Google Scholar
• Jette , KK , Law , D , Schmitt , EA and Kwon , GS . 2004 . Preparation and drug loading of poly(ethylene glycol)-block-poly(-caprolactone) micelles through the evaporation of a cosolvent azeotrope . Pharmaceutical Research , 21 : 1184 – 1191 .
   PubMed Web of Science ®Google Scholar
• Park , KM , Bae , JW , Joung , YK , Shin , JW and Park , KD . 2008 . Nanoaggregate of thermosensitive chitosan-Pluronic for sustained release of hydrophobic drug . Colloids and Surfaces B: Biointerfaces , 63 : 1 – 6 .
   PubMed Web of Science ®Google Scholar
• Gou , M , Zheng , X , Men , K , Zhang , J , Wang , B , Lei , L , Wang , X , Zhao , Y , Luo , F , Chen , L , Zhao , X , Wei , Y and Qian , Z . 2009 . Self-assembled hydrophobic honokiol loaded MPEG-PCL diblock copolymer micelles . Pharmaceutical Research , 26 : 2164 – 2173 .
   PubMed Web of Science ®Google Scholar
• Chiappetta , DA , Degrossi , J , Teves , S , D’Aquino , M , Bregni , C and Sosnik , A . 2008 . Triclosan-loaded poloxamine micelles for enhanced topical antibacterial activity against biofilm . European Journal of Pharmaceutics and Biopharmaceutics , 69 : 535 – 545 .
   PubMed Web of Science ®Google Scholar
• Nishiyama , N , Kato , Y , Sugiyama , Y and Kataoka , K . 2001 . Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system . Pharmaceutical Research , 18 : 1035 – 1041 .
   PubMed Web of Science ®Google Scholar
• Xu , L , Chen , H , Xu , H and Yang , X . 2008 . Anti-tumour and immuno-modulation effects of triptolide-loaded polymeric micelles . European Journal of Pharmaceutics and Biopharmaceutics , 70 : 741 – 748 .
   PubMed Web of Science ®Google Scholar
• Vakil , R , Knilans , K , Andes , D and Kwon , GS . 2008 . Combination antifungal therapy involving amphotericin B, rapamycin and 5-fluorocytosine using PEG-phospholipid micelles . Pharmaceutical Research , 25 : 2056 – 2064 .
   PubMed Web of Science ®Google Scholar
• Ma , Z , Haddadi , A , Molavi , O , Lavasanifar , A , Lai , R and Samuel , J . 2008 . Micelles of poly(ethylene oxide)-b-poly(e-caprolactone) as vehicles for the solubilization, stabilization, and controlled delivery of curcumin . Journal of Biomedical Materials Research , 86A : 300 – 310 .
   Web of Science ®Google Scholar
• Jiang , T , Wang , Z , Tang , L , Mo , F and Chen , C . 2006 . Polymer micellar aggregates of novel amphiphilic biodegradable graft copolymer composed of poly (aspartic acid) derivatives: Preparation, characterization, and effect of pH on aggregation . Journal of Applied Polymer Science , 99 : 2702 – 2709 .
   Web of Science ®Google Scholar
• Jiang , T , Wang , Z , Chen , C , Mo , F , Xu , Y , Tang , L and Liang , J . 2006 . Poly(aspartic-acid) derivatives as polymeric micelle drug delivery systems . Journal of Applied Polymer Science , 101 : 2871 – 2878 .
   Web of Science ®Google Scholar
• Bian , F , Jia , L , Yu , W and Liu , M . 2009 . Self-assembled micelles of N-phthaloylchitosan-g-polyvinylpyrrolidone for drug delivery . Carbohydrate Polymers , 76 : 454 – 459 .
   Web of Science ®Google Scholar
• Francis , MF , Cristea , M , Yang , Y and Winnik , FM . 2005 . Engineering polysaccharide-based polymeric micelles to enhance permeability of cyclosporin A across Caco-2 cells . Pharmaceutical Research , 22 : 209 – 219 .
   PubMed Web of Science ®Google Scholar
• Savi , R , Azzam , T , Eisenberg , A and Maysinger , D . 2006 . Assessment of the integrity of poly(caprolactone)-b-poly(ethylene oxide) micelles under biological conditions: A fluorogenic-based approach . Langmuir , 22 : 3570 – 3578 .
   PubMedGoogle Scholar
• Kwon , GS , Naito , M , Yokoyama , M , Okano , T , Sakurai , Y and Kataoka , K . 1993 . Micelles based on AB block copolymers of poly(ethylene oxide) and poly(β-benzyl L-aspartate) . Langmuir , 9 : 945 – 949 .
   Web of Science ®Google Scholar
• Dowling , KC and Thomas , JK . 1990 . A novel micellar synthesis and photophysical characterization of water-soluble acrylamide-styrene block copolymers . Macromolecules , 23 : 1059 – 1064 .
   Web of Science ®Google Scholar
• Torchilin , VP . 2001 . Structure and design of polymeric surfactant-based drug delivery systems . Journal of Controlled Release , 73 : 137 – 172 .
   PubMed Web of Science ®Google Scholar
• Bourov , GK and Bhattacharya , A . 2005 . Brownian dynamics simulation study of self-assembly of amphiphiles with large hydrophilic heads . Journal of Chemical Physics , 122 : 044702
   PubMedGoogle Scholar
• Suek , NW and Lamm , MH . 2008 . Computer simulation of architectural and molecular weight effects on the assembly of amphiphilic linear-dendritic block copolymers in solution . Langmuir , 24 : 3030 – 3036 .
   PubMedGoogle Scholar
• Gao , Z , Anatoly , NL , Singhal , A and Torchilin , VP . 2002 . Diacyllipid-polymer micelles as nanocarriers for poorly soluble anticancer drugs . Nano Letters , 2 : 979 – 982 .
   Web of Science ®Google Scholar
• Bae , YH and Yin , H . 2008 . Stability issues of polymeric micelles . Journal of Controlled Release , 131 : 2 – 4 .
   PubMed Web of Science ®Google Scholar
• Schick , MJ and Gilbert , AH . 1965 . Effect of urea, guanidinium chloride, and dioxane on the c.m.c. of branched-chain nonionic detergents . Journal of Colloid Science , 20 : 464 – 472 .
   Google Scholar
• Rosen , MJ , Cohen , AW , Dahanayake , M and Hua , X . 1982 . Relationship of structure to properties in surfactants. 10. Surface and thermodynamic properties of 2-dodecyloxypoly(ethenoxyethanol)s, C12H25(OC2H4)xOH, in aqueous solution . Journal of Physical Chemistry , 86 : 541 – 545 .
   Web of Science ®Google Scholar
• Al-Sabagh , AM . 1998 . Surface and thermodynamic properties of p-alkylbenzene polyethoxylated and glycerated sulfonate derivative surfactants . Colloids and Surfaces A: Physicochemical and Engineering Aspects , 134 : 313 – 320 .
   Web of Science ®Google Scholar
• Soga , O , Nostrum , CF , Ramzi , A , Visser , T , Soulimani , F , Frederik , PM , Bomans , PH and Hennink , WE . 2004 . Physicochemical characterization of degradable thermosensitive polymeric micelles . Langmuir , 20 : 9388 – 9395 .
   PubMed Web of Science ®Google Scholar
• Gadelle , F , Koros , WJ and Schechter , RS . 1995 . Solubilization of aromatic solutes in block copolymers . Macromolecules , 28 : 4883 – 4892 .
   Web of Science ®Google Scholar
• Kozlov , MY , Melik-Nubarov , NS , Batrakova , EV and Kabanov , AV . 2000 . Relationship between Pluronic block copolymer structure, critical micellization concentration and partitioning coefficients of low molecular mass solutes . Macromolecules , 33 : 3305 – 3313 .
   Web of Science ®Google Scholar
• Cheng , L and Cao , D . 2009 . Effect of tail architecture on self-assembly of amphiphiles for polymeric micelles . Langmuir , 25 : 2749 – 2756 .
   PubMedGoogle Scholar
• Quintana , JR , Villacampa , M , Munoz , M , Andrio , A and Katime , IA . 1992 . Micellization of a polystyrene-block-poly(ethylene/propylene) copolymer in n-alkanes. 1. Thermodynamic study . Macromolecules , 25 : 3125 – 3129 .
   Google Scholar
• Quintana , JR , Villacampa , M and Katime , IA . 1993 . Micellization of a polystyrene-b-poly(ethylene/propylene) block copolymer in n-dodecane/1,4-dioxane mixtures. 1. Thermodynamics of micellization . Macromolecules , 26 : 601 – 605 .
   Web of Science ®Google Scholar
• Thurn , T , Couderc , S , Sidhu , J , Bloor , DM , Penfold , J , Holzwarth , JF and Wyn-Jones , E . 2002 . Study of mixed micelles and interaction parameters for ABA triblock copolymers of the type EOm-POn-EOm and ionic surfactants: Equilibrium and structure . Langmuir , 18 : 9267 – 9275 .
   Web of Science ®Google Scholar
• Elisseeva , OV , Besseling , NA , Koopal , LK and Cohen , MA . 2005 . Influence of NaCl on the behavior of PEO-PPO-PEO triblock copolymers in solution, at interfaces, and in asymmetric liquid films . Langmuir , 21 : 4954 – 4963 .
   PubMed Web of Science ®Google Scholar
• Alvarez-Lorenzo , C , Gonzalez-Lopez , J , Fernandez-Tarrio , M , Sandez-Macho , I and Concheiro , A . 2007 . Tetronic micellization, gelation and drug solubilization: Influence of pH and ionic strength . European Journal of Pharmaceutics and Biopharmaceutics , 66 : 244 – 252 .
   PubMed Web of Science ®Google Scholar
• Elias , HG . 1973 . Nonionic micelles . Journal of Macromolecular Science-Chemistry , 7 : 601 – 622 .
   Web of Science ®Google Scholar
• Khougaz , K , Gao , Z and Eisenberg , A . 1994 . Determination of the critical micelle concentration of block copolymer micelles by static light scattering . Macromolecules , 27 : 6341 – 6346 .
   Web of Science ®Google Scholar
• El-Ghazawy , RA , Raheem , RA and Al-Sabagh , AM . 2004 . Surface activity-thermodynamic properties and light scattering studies for some novel aliphatic polyester surfactants . Polymers for Advanced Technologies , 15 : 244 – 250 .
   Web of Science ®Google Scholar
• Kalyanasundaram , K and Thomas , JK . 1977 . Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies of micellar systems . Journal of the American Chemical Society , 99 : 2039 – 2044 .
   Web of Science ®Google Scholar
• Dong , DC and Winnik , MA . 1984 . The Py scale of solvent polarities . Canadian Journal of Chemistry , 62 : 2560 – 2565 .
   Web of Science ®Google Scholar
• Abuin , EB and Scaiano , JC . 1984 . Exploratory study of the effect of polyelectrolyte surfactant aggregates on photochemical behavior . Journal of the American Chemical Society , 106 : 6274 – 6283 .
   Web of Science ®Google Scholar
• Almgren , M , Hansson , P , Mukhtar , E and Van Stam , J . 1992 . Aggregation of alkyltrimethylammonium surfactants in aqueous poly(styrenesulfonate) solutions . Langmuir , 8 : 2405 – 2412 .
   Web of Science ®Google Scholar
• Shin , IL , Kim , SY , Lee , YM , Cho , CS and Sung , YK . 1998 . Methoxy poly(ethylene glycol)-ϵ-caprolactone amphiphilic block copolymeric micelle containing indomethacin 1. Preparation and characterization . Journal of Controlled Release , 51 : 1 – 11 .
   PubMed Web of Science ®Google Scholar
• Colombani , O , Ruppel , M , Schubert , F , Zettl , H , Pergushov , DV and Muller , AHE . 2007 . Synthesis of poly(n-butyl acrylate)-block-poly(acrylic acid) diblock copolymers by ATRP and their micellization in water . Macromolecules , 40 : 4338 – 4350 .
   Web of Science ®Google Scholar
• Chen , YW , Alexandridis , P , Su , CK , Patrickios , CS , Hertler , WR and Hatton , TA . 1995 . Effect of block size and sequence on the micellization of ABC triblock methacrylic acid polyampholytes . Macromolecules , 28 : 8604 – 8611 .
   Google Scholar
• Zhang , X , Jackson , JK and Burt , HM . 1996 . Development of amphiphilic diblock copolymers as micellar carriers of taxol . International Journal of Pharmaceutics , 132 : 195 – 206 .
   Web of Science ®Google Scholar
• Zhang , X , Jackson , JK and Burt , HM . 1996 . Determination of surfactant micelle concentration by a novel fluorescence depolarization technique . Journal of Biochemical and Biophysical Methods , 31 : 145 – 150 .
   PubMedGoogle Scholar
• Shi , B , Fang , C , Xian , M , Yan , Y , Shoukuan , Z , Yuan , F and Pei , Y . 2005 . Stealth MePEG-PCL micelles: Effects of polymer composition on micelle physicochemical characteristics, in vitro drug release, in vivo pharmacokinetics in rats and biodistribution in S180 tumor bearing mice . Colloid and Polymer Science , 283 : 954 – 967 .
   Web of Science ®Google Scholar
• Wu , QH , Liang , F , Wei , TZ , Song , XM , Liu , DL and Zhang , GL . 2010 . Synthesis and micellization of an amphiphilic biodegradable β-cyclodextrin/poly(γ-benzyl L-glutamate) copolymer . Journal of Polymer Research , 17 : 183 – 190 .
   Web of Science ®Google Scholar
• Zhang , G , Liang , F , Song , X , Liu , D , Li , M and Wu , Q . 2010 . New amphiphilic biodegradable b-cyclodextrin/poly(L-leucine) copolymers: Synthesis, characterization, and micellization . Carbohydrate Polymers , 80 : 885 – 890 .
   Web of Science ®Google Scholar
• Zhang , W , Li , Y , Liu , L , Sun , Q , Shuai , X , Zhu , W and Chen , Y . 2010 . Amphiphilic toothbrushlike copolymers based on poly(ethylene glycol) and poly(ϵ-caprolactone) as drug carriers with enhanced properties . Biomacromolecules , 11 : 1331 – 1338 .
   PubMed Web of Science ®Google Scholar
• Mohanty , AK , Dilnawaz , F , Mohanty , C and Sahoo , SK . 2010 . Etoposide-loaded biodegradable amphiphilic methoxy (poly ethylene glycol) and poly (e-caprolactone) copolymeric micelles as drug delivery vehicle for cancer therapy . Drug Delivery , 17 : 330 – 342 .
   PubMed Web of Science ®Google Scholar
• Lee , JS , Go , DH , Bae , JW , Lee , SJ and Park , KD . 2007 . Heparin conjugated polymeric micelle for long-term delivery of basic fibroblast growth factor . Journal of Controlled Release , 117 : 204 – 209 .
   PubMed Web of Science ®Google Scholar
• Eckert , AR and Webber , SE . 1996 . Naphthalene-tagged copolymer micelles based on polystyrene-alt-maleic anhydride-graft-poly(ethylene oxide) . Macromolecules , 29 : 560 – 567 .
   Google Scholar
• Teng , Y , Morrison , ME , Munk , P , Webber , SE and Prochazka , K . 1998 . Release kinetics studies of aromatic molecules into water from block polymer micelles . Macromolecules , 31 : 3578 – 3587 .
   Web of Science ®Google Scholar
• Zhang , Y , Jin , T and Zhuo , R . 2005 . Methotrexate-loaded biodegradable polymeric micelles: Preparation, physicochemical properties and in vitro drug release . Colloids and Surfaces B: Biointerfaces , 44 : 104 – 109 .
   PubMedGoogle Scholar
• Trimaille , T , Mondon , K , Gurny , R and Moller , M . 2006 . Novel polymeric micelles for hydrophobic drug delivery based on biodegradable poly(hexyl-substituted lactides) . International Journal of Pharmaceutics , 319 : 147 – 154 .
   PubMed Web of Science ®Google Scholar
• Mikhail , AS and Allen , C . 2010 . Poly(ethylene glycol)-b-poly(ϵ-caprolactone) micelles containing chemically conjugated and physically entrapped docetaxel: Synthesis, characterization, and the influence of the drug on micelle morphology . Biomacromolecules , 11 : 1273 – 1280 .
   PubMed Web of Science ®Google Scholar
• Astafieva , I , Zhong , X and Eisenberg , FA . 1993 . Critical micellization phenomena in block polyelectrolyte solutions . Macromolecules , 26 : 7339 – 7352 .
   Web of Science ®Google Scholar
• Zhang , L and Eisenberg , A . 1998 . Formation of crew-cut aggregates of various morphologies from amphiphilic block copolymers in solution . Polymers for Advanced Technologies , 9 : 677 – 699 .
   Web of Science ®Google Scholar
• Yao , JH , Mya , KY , Li , X , Parameswaran , M , Xu , Q , Loh , KP and Chen , Z . 2008 . Light scattering and luminescence studies on self-aggregation behavior of amphiphilic copolymer micelles . Journal of Physical Chemistry B , 112 : 749 – 755 .
   PubMedGoogle Scholar
• Lin , Y and Alexandridis , P . 2002 . Small-angle neutron scattering characterization of micelles formed by poly(dimethylsiloxane)-graft-polyether copolymers in mixed polar solvents . Journal of Physical Chemistry B , 106 : 12124 – 12132 .
   Web of Science ®Google Scholar
• Soni , SS , Sastry , NV , Aswal , VK and Goyal , PS . 2002 . Micellar structure of silicone surfactants in water from surface activity, SANS and viscosity studies . Journal of Physical Chemistry B , 106 : 2606 – 2617 .
   Web of Science ®Google Scholar
• Ramzi , A , Rijcken , CJF , Veldhuis , T , Schwahn , D , Hennink , WE and Nostrum , C . 2008 . Core-shell structure of degradable, thermosensitive polymeric micelles studied by small-angle neutron scattering . Journal of Physical Chemistry B , 112 : 784 – 792 .
   PubMedGoogle Scholar
• Yokoyama , M , Sugiyama , T , Okano , T , Sakurai , Y , Naito , M and Kataoka , K . 1993 . Analysis of micelle formation of an adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer by gel permeation chromatography . Pharmaceutical Research , 10 : 895 – 899 .
   PubMed Web of Science ®Google Scholar
• Yang , L , Qi , X , Liu , P , Ghazoui , AE and Li , S . 2010 . Aggregation behavior of self-assembling polylactide/poly(ethylene glycol) micelles for sustained drug delivery . International Journal of Pharmaceutics , 394 : 43 – 49 .
   PubMedGoogle Scholar
• Nagasaki , Y , Okada , T , Scholz , C , Iijima , M , Kato , M and Kataoka , K . 1998 . The reactive polymeric micelle based on an aldehyde-ended poly(ethylene glycol)/poly(lactide) block copolymer . Macromolecules , 31 : 1473 – 1479 .
   Web of Science ®Google Scholar
• Yokoyama , M , Miyauchi , M , Yamada , N , Okano , T , Sakurai , Y , Kataoka , K and Inoue , S . 1990 . Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly (aspartic acid) block copolymer . Cancer Research , 50 : 1693 – 1700 .
   PubMed Web of Science ®Google Scholar
• Booth , C and Attwood , D . 2000 . Effects of block architecture and composition on the association properties of poly(oxyalkylene) copolymers in aqueous solution . Macromolecular Rapid Communications , 21 : 501 – 527 .
   Web of Science ®Google Scholar
• Cao , T , Yin , W and Webber , SE . 1994 . Poly(2-vinylnaphthalene-alt-maleic acid)-graft-polystyrene as a photoactive polymer micelle and stabilizer for polystyrene latexes . Macromolecules , 27 : 7459 – 7464 .
   Google Scholar
• Webber , SE . 1998 . Polymer micelles: An example of self-assembling polymers . Journal of Physical Chemistry B , 102 : 2618 – 2626 .
   Web of Science ®Google Scholar
• Sun , H , Guo , B , Li , X , Cheng , R , Meng , F , Liu , H and Zhong , Z . 2010 . Shell-sheddable micelles based on dextran-ss-poly(ϵ-caprolactone) diblock copolymer for efficient intracellular release of doxorubicin . Biomacromolecules , 11 : 848 – 854 .
   PubMed Web of Science ®Google Scholar
• Kim , SY , Shin , IG , Lee , YM , Cho , CS and Sung , YK . 1998 . Methoxy poly(ethylene glycol) and ϵ-caprolactone amphiphilic block copolymeric micelle containing indomethacin. II. Micelle formation and drug release behavior . Journal of Controlled Release , 51 : 13 – 22 .
   PubMed Web of Science ®Google Scholar
• Yu , BG , Okano , T , Kataoka , K and Kwon , G . 1998 . Polymeric micelles for drug delivery: Solubilization and haemolytic activity of amphotericin B . Journal of Controlled Release , 53 : 131 – 136 .
   PubMed Web of Science ®Google Scholar
• Del-real , A , Garcóa-Garduño , MV and Castaño , VM . 1998 . Transmission electron microscopy observations of micelle structure in a vinyl acetate-based microemulsion . International Journal of Polymeric Materials , 42 : 319 – 326 .
   Google Scholar
• Kohori , F , Sakai , K , Aoyagi , T , Yokoyama , M , Sakurai , Y and Okano , T . 1998 . Preparation and characterization of thermally responsive block copolymer micelles comprising poly(N-isopropylacrylamide-b-D,L-lactide) . Journal of Controlled Release , 55 : 87 – 98 .
   PubMed Web of Science ®Google Scholar
• Mueller-Goymann , CC . 2001 . “ Drug delivery: Liquid crystals ” . In Encyclopedia of pharmaceutical technology , Edited by: Swarbrick , J . 1115 – 1131 . New York , NY : Informa Healthcare .
   Google Scholar
• Allemann , E , Leroux , JC and Gurny , R . 1998 . “ Biodegradable nanoparticles of poly(lactic acid) and poly(lactic-co-glycolic acid) for parenteral administration ” . In Pharmaceutical dosage forms: disperse systems , Edited by: Lieberman , H , Rieger , M and Banker , G . 163 – 193 . New York , NY : Marcel Dekker .
   Google Scholar
• Kang , DY , Kim , MJ , Kim , ST , Oh , KS , Yuk , SH and Lee , S . 2008 . Size characterization of drug-loaded polymeric core/shell nanoparticles using asymmetrical flow field-flow fractionation . Analytical and Bioanalytical Chemistry , 390 : 2183 – 2188 .
   PubMedGoogle Scholar
• Winnik , MA , Pekcan , O and Croucher , MD . 1990 . “ Fluorescence techniques in the study of polymer colloid ” . In Scientific methods for the study of polymer colloids and their applications , Edited by: Candau , F and Ottewill , RH . 225 – 246 . Dordrecht : Kluwer Academic .
   Google Scholar
• Winnik , FM , Davidson , AR , Hamer , GR and Kitano , H . 1992 . Amphiphilic poly(N-isopropylacrylamides) prepared by using a lipophilic radical initiator- synthesis and solution properties in water . Macromolecules , 25 : 1876 – 1880 .
   Web of Science ®Google Scholar
• Nivaggioli , T , Tsao , B , Alexandridis , P and Hatton , TA . 1995 . Microviscosity in Pluronic and Tetronic poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles . Langmuir , 11 : 119 – 126 .
   Google Scholar
• Bahadur , P , Sastry , NV , Rao , YK and Riess , G . 1988 . Interaction studies of styreneethylene oxide block copolymers with ionic surfactants in aqeuous solution . Colloids and Surfaces , 29 : 343 – 358 .
   Google Scholar
• Kwon , GS . 2003 . Polymeric micelles for delivery of poorly water-soluble compounds . Critical Reviews in Therapeutic Drug Carrier Systems , 20 : 357 – 403 .
   PubMed Web of Science ®Google Scholar
• Torchilin , VP . 2006 . “ Polymeric micelles as pharmaceutical carriers ” . In Polymers in drug delivery , Edited by: Uchegbu , IF and Schatzlein , AG . 111 – 130 . Boca Raton , FL : Taylor & Francis .
   Google Scholar
• Liu , J , Zeng , F and Allen , C . 2007 . In vivo fate of unimers and micelles of a poly(ethylene glycol)-block-poly(caprolactone) copolymer in mice following intravenous administration . European Journal of Pharmaceutics and Biopharmaceutics , 65 : 309 – 319 .
   PubMed Web of Science ®Google Scholar
• Yang , C , Attia , ABE , Tan , JPK , Ke , X , Gao , S , Hedrick , JL and Yang , YY . 2012 . The role of non-covalent interactions in anticancer drug loading and kinetic stability of polymeric micelles . Biomaterials , 33 : 2971 – 2979 .
   PubMed Web of Science ®Google Scholar
• Lo , CL , Huang , CK , Lin , KM and Hsiue , GH . 2007 . Mixed micelles formed from graft and diblock copolymers for application in intracellular drug delivery . Biomaterials , 28 : 1225 – 1235 .
   PubMed Web of Science ®Google Scholar
• Carstens , MG , Jong , PH , Nostrum , CF , Kemmink , J , Verrijk , R , Leede , LG , Crommelin , DA and Hennink , WE . 2008 . The effect of core composition in biodegradable oligomeric micelles as taxane formulations . European Journal of Pharmaceutics and Biopharmaceutics , 68 : 596 – 606 .
   PubMed Web of Science ®Google Scholar
• Tao , Y , Xu , J , Chen , M , Bai , H and Liu , X . 2012 . Core cross-linked hyaluronan-styrylpyridinium micelles as a novel carrier for paclitaxel . Carbohydrate Polymers , 88 : 118 – 124 .
   Web of Science ®Google Scholar
• Thurmond , KB II , Kowalewski , T and Wooley , KL . 1996 . Water-soluble knedel-like structures: the preparation of shell-cross-linked small particles . Journal of the American Chemical Society , 118 : 7239 – 7240 .
   Web of Science ®Google Scholar
• Kataoka , K , Kwon , GS and Yokoy , M . 1993 . Block copolymer micelles as vehicles for drug delivery . Journal of Controlled Release , 24 : 119 – 132 .
   Web of Science ®Google Scholar
• Chen , L , Xie , Z , Hu , J , Chen , X and Jing , X . 2007 . Enantiomeric PLA-PEG block copolymers and their stereocomplex micelles used as rifampin delivery . Journal of Nanoparticle Research , 9 : 777 – 785 .
   Web of Science ®Google Scholar
• Gaucher , G , Dufresne , M , Sant , VP , Kang , N , Maysinger , D and Leroux , JC . 2005 . Block copolymer micelles: Preparation, characterization and application in drug delivery . Journal of Controlled Release , 109 : 169 – 188 .
   PubMed Web of Science ®Google Scholar
• Mahmud , A , Xiong , XB and Lavasanifar , A . 2006 . Novel self-associating poly(ethylene oxide)-block-poly(1-caprolactone) block copolymers with functional side groups on the polyester block for drug delivery . Macromolecules , 39 : 9419 – 9428 .
   Web of Science ®Google Scholar
• Kim , JO , Kabanov , AV and Bronich , TK . 2009 . Polymer micelles with cross-linked polyanion core for delivery of a cationic drug doxorubicin . Journal of Controlled Release , 138 : 197 – 204 .
   PubMed Web of Science ®Google Scholar
• Zhang , L , Bernard , J , Davis , TP , Barner-Kowollik , C and Stenzel , MH . 2008 . Acid-degradable core-crosslinked micelles prepared from thermosensitive glycopolymers synthesized via RAFT polymerization . Macromolecular Rapid Communications , 29 : 123 – 129 .
   Web of Science ®Google Scholar
• Rosler , A , Vandermeulen , WM and Klok , HA . 2001 . Advanced drug delivery devices via self-assembly of amphiphilic block copolymers . Advanced Drug Delivery Reviews , 53 : 95 – 108 .
   PubMed Web of Science ®Google Scholar
• Murthy , KS , Ma , Q , Clark , CG , Remsen , EE and Wooley , KL . 2001 . Fundamental design aspects of amphiphilic shell-crosslinked nanoparticles for controlled release applications . Chemical Communications , : 773 – 774 .
   Google Scholar
• Huang , H , Remsen , EE , Kowalewski , T and Wooley , KL . 1999 . Nanocages derived from shell cross-linked micelle templates . Journal of the American Chemical Society , 121 : 3805 – 3806 .
   Web of Science ®Google Scholar
• Wang , YC , Li , Y , Sun , TM , Xiong , MH , Wu , J , Yang , YY and Wang , J . 2010 . Core–shell–corona micelle stabilized by reversible cross-linkage for intracellular drug delivery . Macromolecular Rapid Communications , 31 : 1201 – 1206 .
   PubMed Web of Science ®Google Scholar
• Henselwood , F and Liu , G . 1997 . Water-soluble nanospheres of poly(2-cinnamoylethyl methacrylate)-block-poly(acrylic acid) . Macromolecules , 30 : 488 – 493 .
   Google Scholar
• Kakizawa , Y , Harada , A and Kataoka , K . 2001 . Glutathione-sensitive stabilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): a potential carrier for systemic delivery of antisense DNA . Biomacromolecules , 2 : 491 – 497 .
   PubMed Web of Science ®Google Scholar
• Hu , J , Tang , Z , Qiu , X , Pang , X , Yang , Y , Chen , X and Jing , X . 2005 . Formation of flower- or cake-shaped stereocomplex particles from the stereo multiblock copoly(rac-lactide)s . Biomacromolecules , 6 : 2843 – 2850 .
   PubMedGoogle Scholar
• Stager , J and Domb , A . 2003 . Biopolymer stereocomplexes . Advanced Drug Delivery Reviews , 55 : 549 – 583 .
   PubMedGoogle Scholar
• Kang , N , Perron , ME , Prud’homme , RE , Zhang , Y , Gaucher , G and Leroux , JC . 2005 . Stereocomplex block copolymer micelles: Core-shell nanostructures with enhanced stability . Nano Letters , 5 : 315 – 319 .
   PubMed Web of Science ®Google Scholar
• Carstens , MG , Bevernage , JJL , Van Nostrum , CF , Van Steenbergen , MJ , Flesch , FM , Verrijk , R , De Leede , LGJ , Crommelin , DJA and Hennink , WE . 2007 . Small oligomeric micelles based on end group modified mPEG-oligocaprolactone with monodisperse hydrophobic blocks . Macromolecules , 40 : 116 – 122 .
   Web of Science ®Google Scholar
• Watanabe , M , Kawano , K , Yokoyama , M , Opanasopit , P , Okano , T and Maitani , Y . 2006 . Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation and circulation stability . International Journal of Pharmaceutics , 308 : 183 – 189 .
   PubMed Web of Science ®Google Scholar
• Reulen , S and Merkx , M . 2010 . Exchange kinetics of protein-functionalized micelles and liposomes studied by Förster resonance energy transfer . Bioconjugate Chemistry , 21 : 860 – 866 .
   PubMed Web of Science ®Google Scholar
• Sezgin , Z , Yuksel , N and Baykara , T . 2006 . Preparation and characterization of polymeric micelles for solubilization of poorly soluble anticancer drugs . European Journal of Pharmaceutics and Biopharmaceutics , 64 : 261 – 268 .
   PubMed Web of Science ®Google Scholar
• Bugrin , VS , Kozlov , MY , Baskin , II and Melik-Nubarov , NS . 2007 . Intermolecular interactions governing solubilization in micelles of poly(alkylene oxide) surfactants . Polymer Science Series A , 49 : 463 – 472 .
   Google Scholar
• El-Saeed , SM , Farag , RK , Abdul-Raouf , ME and Abdel-Azim , A . 2008 . Synthesis and characterization of novel crude oil dispersants based on ethoxylated schiff base . International Journal of Polymeric Materials , 57 : 860 – 877 .
   Web of Science ®Google Scholar
• Chiappetta , DA and Sosnik , A . 2007 . Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs . European Journal of Pharmaceutics and Biopharmaceutics , 66 : 303 – 317 .
   PubMed Web of Science ®Google Scholar
• Chi , SC , Yeom , D , Kim , SC and Park , ES . 2003 . A polymeric micellar carrier for the solubilization of biphenyl dimethyl dicarboxylate . Archives of Pharmacal Research , 26 : 173 – 181 .
   PubMed Web of Science ®Google Scholar
• Kulthe , SS , Inamdar , NN , Choudhari , YM , Shirolikar , SM , Borde , LC and Mourya , VK . 2011 . Mixed micelle formation with hydrophobic and hydrophilic Pluronic block copolymers: Implications for controlled and targeted drug delivery . Colloids and Surfaces B: Biointerfaces , 88 : 691 – 696 .
   PubMed Web of Science ®Google Scholar
• Witt , KA , Huber , JD , Egleton , RD and Davis , TP . 2002 . Pluronic P85 copolymer enhances opioid peptide analgesia . Journal of Pharmacology and Experimental Therapeutics , 303 : 760 – 767 .
   PubMedGoogle Scholar
• Gao , Y , Li , LB and Zhai , G . 2008 . Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin . Colloids and Surfaces B: Biointerfaces , 64 : 194 – 199 .
   PubMed Web of Science ®Google Scholar
• Mondon , K , Zeisser-Labouèbe , M , Gurny , R and Möller , M . 2011 . Novel Cyclosporin A formulations using MPEG–hexyl-substituted polylactide micelles: A suitability study . European Journal of Pharmaceutics and Biopharmaceutics , 77 : 56 – 65 .
   PubMed Web of Science ®Google Scholar
• Chiappetta , DA , Hocht , C , Taira , C and Sosnik , A . 2011 . Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles . Biomaterials , 32 : 2379 – 2387 .
   PubMed Web of Science ®Google Scholar
• Kabanov , AV , Ckekhonin , VP , Alakhov , V , Batrakova , EV , Lebedev , AS , Melik-Nubarov , NS , Arzhakov , S , Levashov , AV , Morozov , GV , Severin , ES and Kabanov , VA . 1989 . The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles . FEBS Letters , 258 : 343 – 345 .
   PubMed Web of Science ®Google Scholar
• Kadam , Y , Yerramilli , U , Bahadur , A and Bahadur , P . 2011 . Micelles from PEO–PPO–PEO block copolymers as nanocontainers for solubilization of a poorly water soluble drug hydrochlorothiazide . Colloids and Surfaces B: Biointerfaces , 83 : 49 – 57 .
   PubMed Web of Science ®Google Scholar
• Yang , L , Kuang , J , Wang , J , Li , Z and Zhang , LM . 2008 . Loading and in vitro controlled release of indomethacin using amphiphilic cholesteryl-bearing carboxymethylcellulose derivatives . Macromolecular Bioscience , 8 : 279 – 286 .
   PubMedGoogle Scholar
• Alakhov , V , Pietrzynski , G , Patel , K , Kabanov , A , Bromberg , L and Hatton , TA . 2004 . Pluronic block copolymers and Pluronic poly(acrylic acid) microgels in oral delivery of megestrol acetate . Journal of Pharmacy and Pharmacology , 56 : 1233 – 1241 .
   PubMed Web of Science ®Google Scholar
• Dumortier , G , Groissord , JL , Zuber , M , Couarraze , G and Chaumeil , JC . 1991 . Rheological study of a thermoreversible morphine gel . Drug Development and Industrial Pharmacy , 17 : 1255 – 1265 .
   Web of Science ®Google Scholar
• Parekh , P , Singh , K , Marangoni , DG and Bahadur , P . 2011 . Micellization and solubilization of a model hydrophobic drug nimesulide in aqueous salt solutions of Tetronic® T904 . Colloids and Surfaces B: Biointerfaces , 83 : 69 – 77 .
   PubMedGoogle Scholar
• Croy , SR and Kwon , GS . 2004 . The effects of Pluronic block copolymers on the aggregation state of nystatin . Journal of Controlled Release , 95 : 161 – 171 .
   PubMed Web of Science ®Google Scholar
• Mo , R , Jin , X , Li , N , Ju , C , Sun , M , Zhang , C and Ping , Q . 2011 . The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles . Biomaterials , 32 : 4609 – 4620 .
   PubMed Web of Science ®Google Scholar
• Momot , KI , Kuchel , PW , Deo , P and Whittaker , D . 2003 . NMR study of the association of propofol with nonionic surfactants . Langmuir , 19 : 2088 – 2095 .
   Web of Science ®Google Scholar
• Xiong , MP , Yanez , JA , Kwon , GS , Davies , NM and Forrest , ML . 2009 . A cremophor-free formulation for tanespimycin (17-AAG) using PEO-b-PDLLA micelles: Characterization and pharmacokinetics in rats . Journal of Pharmaceutical Sciences , 98 : 1577 – 1586 .
   PubMed Web of Science ®Google Scholar
• El-Kamel , AH . 2002 . In vitro and in vivo evaluation of Pluronic F127- based ocular delivery system for timolol maleate . International Journal of Pharmaceutics , 241 : 47 – 55 .
   PubMed Web of Science ®Google Scholar
• Lee , H , Zeng , F , Dunne , M and Allen , C . 2005 . Methoxy poly(ethylene glycol)-block-poly(δ-valerolactone) copolymer micelles for formulation of hydrophobic drugs . Biomacromolecules , 6 : 3119 – 3128 .
   PubMed Web of Science ®Google Scholar
• Kabanov , AV and Alakov , VY . 2002 . Pluronic block copolymers in drug delivery: From micellar nanocontainers to biological response modifiers . Critical Reviews in Therapeutic Drug Carrier Systems , 19 : 1 – 73 .
   PubMed Web of Science ®Google Scholar
• Liu , JB , Xiao , YH and Allen , C . 2004 . Polymer-drug compatibility: a guide to the development of delivery systems for the anticancer agent, ellipticine . Journal of Pharmaceutical Sciences , 93 : 132 – 143 .
   PubMed Web of Science ®Google Scholar
• Ribeiro , ME , Cavalcante , IM , Ricardo , NM , Mai , SM , Attwood , D , Yeates , SG and Booth , C . 2009 . Solubilisation of griseofulvin in aqueous micellar solutions of diblock copolymers of ethylene oxide, 1,2-butylene oxide with lengthy B blocks . International Journal of Pharmaceutics , 369 : 196 – 198 .
   PubMedGoogle Scholar
• Chen , X , Ding , S , Qu , G and Zhang , C . 2008 . Synthesis of novel chitosan derivatives for micellar solubilization of cyclosporine A . Journal of Bioactive and Compatable Polymers , 23 : 563 – 578 .
   Web of Science ®Google Scholar
• Dong , Y , Jin , Y and Wei , D . 2007 . Surface activity and solubilization of a novel series of functional polyurethane surfactants . Polymer International , 56 : 14 – 21 .
   Web of Science ®Google Scholar
• Zhou , Z , Chaibundit , C , D’Emanuele , A , Lennon , K , Attwood , D and Booth , C . 2008 . Solubilisation of drugs in worm-like micelles of block copolymers of ethylene oxide and 1,2-butylene oxide in aqueous solution . International Journal of Pharmaceutics , 354 : 82 – 87 .
   PubMedGoogle Scholar
• Nagarajan , R . 1999 . Solubilization of hydrocarbons and resulting aggregate shape transitions in aqueous solutions of Pluronic (PEO-PPO-PEO) block copolymers . Colloids and Surfaces B: Biointerfaces , 16 : 55 – 72 .
   Web of Science ®Google Scholar
• Bae , Y , Fukushima , S , Harada , A and Kataoka , K . 2003 . Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change . Angewandte Chemie International Edition , 42 : 4640 – 4643 .
   PubMed Web of Science ®Google Scholar
• Van Hasselt , PM , Janssens , GEPJ , Slot , TK , Van der Ham , M , Minderhoud , TC , Talelli , M , Akkermans , LM , Rijcken , CJF and Van Nostrum , CF . 2009 . The influence of bile acids on the oral bioavailability of vitamin K encapsulated in polymeric micelles . Journal of Controlled Release , 133 : 161 – 168 .
   PubMed Web of Science ®Google Scholar
• Zastre , J , Jackson , J and Burt , H . 2004 . Pharmaceutical Research , 21 : 1489
   PubMed Web of Science ®Google Scholar
• Sharma , AK , Zhang , L , Li , S , Kelly , DL , Alakhov , VY , Batrakova , EV and Kabanov , AV . 2008 . Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant . Journal of Controlled Release , 131 : 220 – 227 .
   PubMed Web of Science ®Google Scholar
• Zhang , Y , Li , X , Zhou , Y , Wang , X , Fan , Y , Huang , Y and Liu , Y . 2010 . Preparation and evaluation of poly(ethylene glycol)-poly(lactide) micelles as nanocarriers for oral delivery of cyclosporine A . Nanoscale Research Letters , 5 : 917 – 925 .
   PubMed Web of Science ®Google Scholar
• Sant , VP , Smith , D and Leroux , JC . 2005 . Enhancement of oral bioavailability of poorly water-soluble drugs by poly(ethylene glycol)-block-poly(alkyl acrylate-co-methacrylic acid) self-assemblies . Journal of Controlled Release , 104 : 289 – 300 .
   PubMed Web of Science ®Google Scholar
• Han , LM , Guo , J , Zhang , LJ , Wang , QS and Fang , XL . 2006 . Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with Pluronic P123 . Acta Pharmacologica Sinica , 27 : 747 – 753 .
   PubMed Web of Science ®Google Scholar
• Aliabadi , HM , Brocks , DR and Lavasanifar , A . 2005 . Polymeric micelles for the solublization and delivery of cyclosporine A: pharmacokinetics and biodistribution . Biomaterials , 26 : 7251 – 7259 .
   PubMed Web of Science ®Google Scholar
• Aliabadi , HM , Elhasi , S , Brocks , DR and Lavasanifar , A . 2008 . Polymeric micellar delivery reduces kidney distribution and nephrotoxic effects of cyclosporine A after multiple dosing . Journal of Pharmaceutical Sciences , 97 : 1916 – 1926 .
   PubMed Web of Science ®Google Scholar
• Kawakami , S , Opanasopit , P , Yokoyama , M , Chansri , N , Yamamoto , T , Okano , T , Yamashita , F and Hashida , M . 2005 . Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration . Journal of Pharmaceutical Sciences , 94 : 2606 – 2615 .
   PubMed Web of Science ®Google Scholar
• Chansri , N , Kawakami , S , Yokoyama , M , Yamamoto , T , Charoensit , P and Hashida , M . 2008 . Anti-tumor effect of all-trans retinoic acid loaded polymeric micelles in solid tumor bearing mice . Pharmaceutical Research , 25 : 428 – 434 .
   PubMed Web of Science ®Google Scholar
• Soga , O , Van Nostrum , CF , Fens , M , Rijcken , CJF , Schiffelers , RM , Storm , G and Hennink , WE . 2005 . Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery . Journal of Controlled Release , 103 : 341 – 353 .
   PubMed Web of Science ®Google Scholar
• Uchida , Y and Murakami , Y . 2010 . Trilayered polymeric micelle: A newly developed macromolecular assembly that can incorporate hydrophilic compounds . Colloids and Surfaces B: Biointerfaces , 79 : 198 – 204 .
   PubMedGoogle Scholar
• Uchida , Y and Murakami , Y . 2011 . Successful preferential formation of a novel macromolecular assembly—Trilayered polymeric micelle—That can incorporate hydrophilic compounds: The optimization of factors affecting the micelle formation from amphiphilic block copolymers . Colloids and Surfaces B: Biointerfaces , 84 : 346 – 353 .
   PubMedGoogle Scholar
• Lukyanov , AN , Gao , Z , Mazzola , L and Torchilin , VP . 2002 . Polyethylene glycol-diacyllipid micelles demonstrate increased acculumation in subcutaneous tumors in mice . Pharmaceutical Research , 19 : 1424 – 1429 .
   PubMed Web of Science ®Google Scholar
• Grislain , L , Couvreur , P , Lenaerts , V , Roland , M , Deprez-Decampeneere , D and Speiser , P . 1983 . Pharmacokinetics and distribution of a biodegradable drug-carrier . International Journal of Pharmaceutics , 15 : 335 – 345 .
   Web of Science ®Google Scholar
• Remant Bahadur , KC , Aryal , S , Bhattarai , SR , Khil , MS and Kim , HY . 2007 . Amphiphilic triblock copolymer based on poly(p-dioxanone) and poly(ethylene glycol): Synthesis, characterization, and aqueous dispersion . Journal of Applied Polymer Science , 103 : 2695 – 2702 .
   Web of Science ®Google Scholar
• Okuda , T , Kawakami , S , Higuchi , Y , Satoh , T , Oka , Y , Yokoyama , M , Yamashita , F and Hashida , M . 2009 . Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles . International Journal of Pharmaceutics , 373 : 100 – 106 .
   PubMedGoogle Scholar
• Sayyah , SM , Abd El-Salam , HM and Azzam , EMS . 2005 . Surface activity of monomeric and polymeric (3-alkyloxy aniline) surfactants . International Journal of Polymeric Materials , 54 : 541 – 555 .
   Google Scholar
• Opanasopit , P , Yokoyama , M , Watanabe , M , Kawano , K , Maitani , Y and Okano , T . 2004 . Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting . Pharmaceutical Research , 21 : 2001 – 2008 .
   PubMed Web of Science ®Google Scholar
• Vakil , R and Kwon , GS . 2006 . Poly(ethylene glycol)-b-poly(ϵ-caprolactone) and PEG-phospholipid form stable mixed micelles in aqueous media . Langmuir , 22 : 9723 – 9729 .
   PubMedGoogle Scholar
• Xiong , XY , Tam , KC and Gan , LH . 2003 . Synthesis and aggregation behavior of pluronic f127/poly(lactic acid) block copolymers in aqueous solutions . Macromolecules , 36 : 9979 – 9985 .
   Web of Science ®Google Scholar
• Xiong , XY , Tam , KC and Gan , LH . 2004 . Hydrolytic degradation of Pluronic F127/poly(lactic acid) block copolymer nanoparticles . Macromolecules , 37 : 3425 – 3430 .
   Web of Science ®Google Scholar
• Yokoyama , M and Okano , T . 1996 . Targetable drug carriers: Present status and a future perspective . Advanced Drug Delivery Reviews , 21 : 77 – 80 .
   Web of Science ®Google Scholar
• Lukyanov , AN and Torchilin , VP . 2004 . Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs . Advanced Drug Delivery Reviews , 56 : 1273 – 1289 .
   PubMed Web of Science ®Google Scholar
• Vlerken , LE , Vyas , TK and Amiji , MM . 2007 . Poly(ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery . Pharmaceutical Research , 24 : 1405 – 1414 .
   PubMed Web of Science ®Google Scholar
• Maeda , H , Greish , K and Fang , J . 2006 . The EPR effect and polymeric drugs: A paradigm shift for cancer chemotherapy in the 21st century . Advances in Polymer Science , 193 : 103 – 121 .
   Web of Science ®Google Scholar
• Matsumura , Y . 2008 . Poly(amino acid) micelle nanocarriers in preclinical and clinical studies . Advanced Drug Delivery Reviews , 60 : 899 – 914 .
   PubMed Web of Science ®Google Scholar
• Jagur-Grodzinski , J . 2008 . Polymers for targeted and/or sustained drug delivery . Polymers for Advanced Technologies , 19 : 1 – 12 .
   Google Scholar
• Vetvicka , D , Hruby , M , Hovorka , O , Etrych , T , Vetrik , M , Kovar , L , Kovar , M , Ulbrich , K and Rihova , B . 2009 . Biological evaluation of polymeric micelles with covalently bound doxorubicin . Bioconjugate Chemistry , 20 : 2090 – 2097 .
   PubMed Web of Science ®Google Scholar
• Gillies , ER and Fréchet , JM . 2004 . Development of acid-sensitive copolymer micelles for drug delivery . Pure and Applied Chemistry , 76 : 1295 – 1307 .
   Google Scholar
• Kim , MS , Hwang , SJ , Han , JK , Choi , EK , Park , HJ , Kim , JS and Lee , DS . 2006 . pH-responsive PEG-poly(b-amino ester) block copolymer micelles with a sharp transition . Macromolecular Rapid Communications , 27 : 447 – 451 .
   Web of Science ®Google Scholar
• Rodriguez-Hernandez , J , Checot , F , Gnanou , Y and Lecommandoux , S . 2005 . Toward ‘smart’ nano-objects by self-assembly of block copolymers in solution . Progress in Polymer Science , 30 : 691 – 724 .
   Web of Science ®Google Scholar
• Sethuraman , VA , Lee , MC and Bae , YH . 2008 . A biodegradable pH-sensitive micelle system for targeting acidic solid tumors . Pharmaceutical Research , 25 : 657 – 666 .
   PubMed Web of Science ®Google Scholar
• Schmaljohann , D . 2006 . Thermo- and pH-responsive polymers in drug delivery . Advanced Drug Delivery Reviews , 58 : 1655 – 1670 .
   PubMed Web of Science ®Google Scholar
• Lee , ES , Gao , Z , Kim , D , Park , K , Kwon , IC and Bae , YH . 2008 . Super pH-sensitive multifunctional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance . Journal of Controlled Release , 129 : 228 – 236 .
   PubMed Web of Science ®Google Scholar
• Gu , J , Cheng , WP , Liu , J , Lo , SY , Smith , D , Qu , X and Yang , Z . 2008 . pH-triggered reversible “stealth” polycationic micelles . Biomacromolecules , 9 : 255 – 262 .
   PubMedGoogle Scholar
• Yoo , HS , Lee , EA and Park , TG . 2002 . Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages . Journal of Controlled Release , 82 : 17 – 27 .
   PubMed Web of Science ®Google Scholar
• Mohajer , G , Lee , ES and Bae , YH . 2007 . Enhanced intercellular retention activity of novel pH-sensitive polymeric micelles in wild and multidrug resistant MCF-7 cells . Pharmaceutical Research , 24 : 1618 – 1627 .
   PubMed Web of Science ®Google Scholar
• Oh , KT , Lee , ES , Kim , D and Bae , YH . 2008 . l-Histidine-based pH-sensitive anticancer drug carrier micelle: Reconstitution and brief evaluation of its systemic toxicity . International Journal of Pharmaceutics , 358 : 177 – 183 .
   PubMed Web of Science ®Google Scholar
• Lin , J , Zhu , J , Chen , T , Lin , S , Cai , C , Zhang , L , Zhuang , Y and Wang , XS . 2009 . Drug releasing behavior of hybrid micelles containing polypeptide triblock copolymer . Biomaterials , 30 : 108 – 117 .
   PubMed Web of Science ®Google Scholar
• Xiong , XB , Mahmud , A , Uludag , H and Lavasanifar , A . 2008 . Multifunctional polymeric micelles for enhanced intracellular delivery of doxorubicin to metastatic cancer cells . Pharmaceutical Research , 25 : 2555 – 2566 .
   PubMed Web of Science ®Google Scholar
• Kim , S , Kim , JY , Huh , KM , Acharya , G and Park , K . 2008 . Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel . Journal of Controlled Release , 132 : 222 – 229 .
   PubMed Web of Science ®Google Scholar
• Dewhirst , MW , Viglianti , BL , Lora-Michiels , M , Hanson , M and Hoopes , PJ . 2003 . Adverse temperature levels in the human-proceedings of the WHO conference . International Journal of Hyperthermia , 19 : 267 – 294 .
   PubMed Web of Science ®Google Scholar
• Kampinga , HH . 2006 . Cell biological effects of hyperthermia alone or combined with radiation or drugs: A short introduction to newcomers in the field . International Journal of Hyperthermia , 22 : 191 – 196 .
   PubMed Web of Science ®Google Scholar
• Falk , MH and Issels , RD . 2001 . Hyperthermia in oncology . International Journal of Hyperthermia , 17 : 1 – 18 .
   PubMed Web of Science ®Google Scholar
• Dreher , MR , Liu , W , Michelich , CR , Dewhirst , MW and Chilkoti , A . 2007 . Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors . Cancer Research , 67 : 4418 – 4424 .
   PubMed Web of Science ®Google Scholar
• Chilkoti , A , Dreher , MR , Meyer , DE and Raucher , D . 2002 . Targeted drug delivery by thermally responsive polymers . Advanced Drug Delivery Reviews , 54 : 613 – 630 .
   PubMed Web of Science ®Google Scholar
• Gaber , MH , Wu , NZ , Hong , K , Huang , SK , Dewhirst , MW and Papahadjopoulos , D . 1996 . Thermosensitive liposomes: Extravasation and release of contents in tumor microvascular networks . International Journal of Radiation Oncology Biology Physics , 36 : 1177 – 1187 .
   PubMed Web of Science ®Google Scholar
• Riehemann , K , Schmitt , O and Ehlers , EM . 2005 . The effects of thermochemotherapy using cyclophosphamide plus hyperthermia on the malignant pleural mesothelioma in vivo . Annals of Anatomy , 187 : 215 – 223 .
   PubMed Web of Science ®Google Scholar
• Dewhirst , MW , Prosnitz , L , Thrall , D , Prescott , D , Clegg , S , Charles , C , MacFall , J , Rosner , G , Samulski , T , Gillette , E and LaReu , S . 1997 . Hyperthermic treatment of malignant diseases: Current status and a view toward the future . Seminars in Oncology , 24 : 616 – 625 .
   PubMed Web of Science ®Google Scholar
• Schild , HG . 1992 . Poly(N-isopropylacrylamide): Experiment, theory and application . Progress in Polymer Science , 17 : 163 – 249 .
   Web of Science ®Google Scholar
• Kong , G and Dewhirst , MW . 1999 . Review- hyperthermia and liposomes . International Journal of Hyperthermia , 15 : 345 – 370 .
   PubMed Web of Science ®Google Scholar
• Heskins , M and Guillet , JE . 1968 . Solution properties of poly(N-isopropylacrylamide) . Journal of Macromolecular Science-Chemistry , A2 : 1441 – 1455 .
   Google Scholar
• Fujishige , S , Kubota , K and Ando , I . 1989 . Phase transition of aqueous solutions of poly(N-isopropylacrylamide) and poly(N-isopropylmethacrylamide) . Journal of Physical Chemistry , 93 : 3311 – 3313 .
   Web of Science ®Google Scholar
• Yang , M , Ding , YT , Zhang , LY , Qian , XP , Jiang , XQ and Liu , BR . 2007 . Novel thermosensitive polymeric micelles for docetaxel delivery . Journal of Biomedical Materials Research , 81A : 847 – 857 .
   Web of Science ®Google Scholar
• Liu , B , Yang , M , Li , R , Ding , Y , Qian , X , Yu , L and Jiang , X . 2008 . The antitumor effect of novel docetaxel-loaded thermosensitive micelles . European Journal of Pharmaceutics and Biopharmaceutics , 69 : 527 – 534 .
   PubMed Web of Science ®Google Scholar
• Santis , SD , Ladogana , RD , Diociaiuti , M and Masci , G . 2010 . Pegylated and thermosensitive polyion complex micelles by self-assembly of two oppositely and permanently charged diblock copolymers . Macromolecules , 43 : 1992 – 2001 .
   Google Scholar
• Takei , YG , Aoki , T , Sanui , K , Ogata , N , Okano , T and Sakurai , Y . 1993 . Temperature-responsive bioconjugates. 2. Molecular design for temperature-modulated bioseparations . Bioconjugate Chemistry , 4 : 341 – 346 .
   PubMed Web of Science ®Google Scholar
• Luo , S , Ling , C , Hu , X , Liu , X , Chen , S , Han , M and Xia , J . 2011 . Thermoresponsive unimolecular micelles with a hydrophobic dendritic core and a double hydrophilic block copolymer shell . Journal of Colloid and Interface Science , 353 : 76 – 82 .
   PubMedGoogle Scholar
• Bian , F , Xiang , M , Yu , W and Liu , M . 2008 . Preparation and self-assembly behavior of thermosensitive polymeric micelles comprising poly(styrene-b-N,N-diethylacrylamide) . Journal of Applied Polymer Science , 110 : 900 – 907 .
   Google Scholar
• Rijcken , CJF , Veldhuis , TFJ , Ramzi , A , Meeldijk , JD , Nostrum , CF and Hennink , WE . 2005 . Novel fast degradable thermosensitive polymeric micelles based on PEG-block-poly(N-(2-hydroxyethyl)methacrylamide-oligolactates) . Biomacromolecules , 6 : 2343 – 2351 .
   PubMed Web of Science ®Google Scholar
• Ju , B , Yan , D and Zhang , S . 2012 . Micelles self-assembled from thermoresponsive 2-hydroxy-3-butoxypropyl starches for drug delivery . Carbohydrate Polymers , 87 : 1404 – 1409 .
   Google Scholar
• Qiao , P , Niu , Q , Wang , Z and Cao , D . 2010 . Synthesis of thermosensitive micelles based on poly(N-isopropylacrylamide) and poly(l-alanine) for controlled release of adriamycin . Chemical Engineering Journal , 159 : 257 – 263 .
   Google Scholar
• Li , W , Tu , W and Cao , D . 2009 . Synthesis of thermoresponsive polymeric micelles of PNIPAAm-b-OMMA as a drug carrier for loading and controlled release of prednisolone . Journal of Applied Polymer Science , 111 : 701 – 708 .
   Google Scholar
• Li , G , Guo , L and Ma , S . 2009 . Self-assembly and drug delivery behaviors of thermo-sensitive poly(t-butyl acrylate)-b-poly (N-isopropylacrylamide) micelles . Journal of Applied Polymer Science , 113 : 1364 – 1368 .
   Google Scholar
• Qu , T , Wang , A , Yuan , J and Gao , Q . 2009 . Preparation of an amphiphilic triblock copolymer with pH- and thermo-responsiveness and self-assembled micelles applied to drug release . Journal of Colloid and Interface Science , 336 : 865 – 871 .
   PubMedGoogle Scholar
• Zhang , ZX , Liu , X , Xu , FJ , Loh , XJ , Kang , ET , Neoh , KG and Li , J . 2008 . Pseudo-block copolymer based on star-shaped poly(N-isopropylacrylamide) with β-cyclodextrin core and guest-bearing PEG: Controlling thermoresponsivity through supramolecular self-assembly . Macromolecules , 41 : 5967 – 5970 .
   Web of Science ®Google Scholar
• Liu , Y , Wu , J , Meng , L , Zhang , L and Lu , X . 2008 . Self-assembled, fluorescent polymeric micelles of a graft copolymer containing carbazole for thermo-controlled drug delivery in vitro . Journal of Biomedical Materials Research Part B: Applied Biomaterials , 85B : 435 – 443 .
   Google Scholar
• Zhang , ZX , Qiu , LY , Zhu , KJ and Jin , Y . 2004 . Thermosensitive micelles self-assembled by novel N-isopropylacrylamide oligomer grafted polyphosphazene . Macromolecular Rapid Communications , 25 : 1563 – 1567 .
   Google Scholar
• Liyan , Q , Jianxiang , Z , Yi , J and Kangjie , Z . 2005 . Thermosensitive self-assembly behaviors of novel amphiphilic polyphosphazenes . Chinese Science Bulletin , 50 : 1453 – 1455 .
   Google Scholar
• Kim , IS , Jeong , Y , Lee , YH and Kim , SH . 2000 . Drug release from thermo-responsive self-assembled polymeric micelles composed of cholic acid and poly(N-isopropylacrylamide) . Archives of Pharmacal Research , 23 : 367 – 373 .
   PubMed Web of Science ®Google Scholar
• Tomlinson , R , Klee , M , Garrett , S , Heller , J , Duncan , R and Brocchini , S . 2002 . Pendent chain functionalized polyacetals that display pH-dependent degradation: A platform for the development of novel polymer therapeutics . Macromolecules , 35 : 473 – 480 .
   Web of Science ®Google Scholar
• Dong , LC and Hoffman , AS . 1991 . A novel-approach for preparation of pH-sensitive hydrogels for enteric drug delivery . Journal of Controlled Release , 15 : 141 – 152 .
   Web of Science ®Google Scholar
• Yin , X , Hoffman , AS and Stayton , PS . 2006 . Poly(N-isopropylacrylamide-co-propylacrylic acid) copolymers that respond sharply to temperature and pH . Biomacromolecules , 7 : 1381 – 1385 .
   PubMed Web of Science ®Google Scholar
• Zhang , LY , Guo , R , Yang , M , Jiang , XQ and Liu , BR . 2007 . Thermo and pH dual-responsive nanoparticles for anti-cancer drug delivery . Advanced Materials , 19 : 2988 – 2992 .
   Web of Science ®Google Scholar
• Liu , Y , Cao , X , Luo , X , Le , Z and Xu , W . 2009 . Self-assembled micellar nanoparticles of a novel star copolymer for thermo and pH dual-responsive drug release . Journal of Colloid and Interface Science , 329 : 244 – 252 .
   PubMed Web of Science ®Google Scholar
• Lokitz , BS , York , AW , Stempka , JE , Treat , ND , Li , Y , Jarrett , WL and McCormick , CL . 2007 . Aqueous RAFT synthesis of micelle-forming amphiphilic block copolymers containing N-acryloylvaline. Dual mode, temperature/ ph responsiveness, and “locking” of micelle structure through interpolyelectrolyte complexation . Macromolecules , 40 : 6473 – 6480 .
   Google Scholar
• Huang , X , Du , F , Cheng , J , Dong , Y , Liang , D , Ji , S , Lin , SS and Li , Z . 2009 . Acid-sensitive polymeric micelles based on thermoresponsive block copolymers with pendent cyclic orthoester groups . Macromolecules , 42 : 783 – 790 .
   Google Scholar
• Koo , AN , Min , KH , Lee , HJ , Lee , SU , Kim , K , Kwon , IC , Cho , SH , Jeong , SY and Lee , SC . 2012 . Tumor accumulation and antitumor efficacy of docetaxel-loaded core-shell-corona micelles with shell-specific redox-responsive cross-links . Biomaterials , 33 : 1489 – 1499 .
   PubMed Web of Science ®Google Scholar
• Saito , G , Swanson , JA and Lee , KD . 2003 . Drug delivery strategy utilizing conjugation via reversible disulfide linkages: Role and site of cellular reducing activities . Advanced Drug Delivery Reviews , 55 : 199 – 215 .
   PubMed Web of Science ®Google Scholar
• Li , J , Huo , M , Wang , J , Zhou , J , Mohammada , JM , Zhang , Y , Zhu , Q , Waddad , AY and Zhang , Q . 2012 . Redox-sensitive micelles self-assembled from amphiphilic hyaluronic aciddeoxycholic acid conjugates for targeted intracellular delivery of paclitaxel . Biomaterials , 33 : 2310 – 2320 .
   PubMed Web of Science ®Google Scholar
• Meng , FH , Hennink , WE and Zhong , Z . 2009 . Reduction-sensitive polymers and bioconjugates for biomedical applications . Biomaterials , 30 : 2180 – 2198 .
   PubMed Web of Science ®Google Scholar
• Raina , S and Missiakas , D . 1997 . Making and breaking disulfide bonds . Annual Review of Microbiology , 51 : 179 – 202 .
   PubMed Web of Science ®Google Scholar
• Gilbert , HF . 1995 . Thiol/disulfide exchange equilibria and disulfide bond stability . Methods in Enzymology , 251 : 8 – 28 .
   PubMed Web of Science ®Google Scholar
• Ghosh , S , Yesilyurt , V , Savariar , EN , Irvin , K and Thayumanavan , S . 2009 . Redox, ionic strength, and pH sensitive supramolecular polymer assemblies . Journal of Polymer Science Part A: Polymer Chemistry , 8 : 1052 – 1060 .
   Google Scholar
• Koo , AN , Lee , HJ , Kim , SE , Chang , JH , Park , C , Kim , C , Park , JH and Lee , SC . 2008 . Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery . Chemical Communications , 48 : 6570 – 6572 .
   PubMed Web of Science ®Google Scholar
• Zhang , J , Jiang , X , Zhang , Y , Li , Y and Liu , S . 2007 . Facile fabrication of reversible core cross-linked micelles possessing thermosensitive swellability . Macromolecules , 40 : 9125 – 9132 .
   Web of Science ®Google Scholar
• Navath , RS , Wang , B , Kannan , S , Romero , R and Kannan , RM . 2010 . Stimuli-responsive star poly(ethylene glycol) drug conjugates for improved intracellular delivery of the drug in neuroinflammation . Journal of Controlled Release , 142 : 447 – 456 .
   PubMed Web of Science ®Google Scholar
• Bulmus , V , Woodward , M , Lin , L , Murthy , N , Stayton , P and Hoffman , A . 2003 . A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs . Journal of Controlled Release , 93 : 105 – 120 .
   PubMed Web of Science ®Google Scholar
• Mitragotri , S , Blankschtein , D and Langer , R . 1995 . Ultrasound-mediated transdermal protein delivery . Science , 269 : 850 – 853 .
   PubMed Web of Science ®Google Scholar
• Rapoport , NY , Christensen , DA , Fain , HD , Barrows , L and Gao , Z . 2004 . Ultrasound-triggered drug targeting of tumors in vitro and in vivo . Ultrasonics , 42 : 943 – 950 .
   PubMed Web of Science ®Google Scholar
• Mitragotri , S and Kost , J . 2004 . Low-frequency sonophoresis: A review . Advanced Drug Delivery Reviews , 56 : 589 – 601 .
   PubMed Web of Science ®Google Scholar
• Mitragotri , S . 2005 . Healing sound: The use of ultrasound in drug delivery and other therapeutic applications . Nature reviews: Drug discovery , 4 : 255 – 260 .
   PubMed Web of Science ®Google Scholar
• Nelson , JL , Roeder , BL , Carmen , JC , Roloff , F and Pitt , WG . 2002 . Ultrasonically activated chemotherapeutic drug delivery in a rat model . Cancer Research , 62 : 7280 – 7283 .
   PubMed Web of Science ®Google Scholar
• Husseini , GA , Diaz de la Rosa , MA , Gabuji , T , Zeng , Y , Christensen , DA and Pitt , WG . 2007 . Release of doxorubicin from unstabilized and stabilized micelles under the action of ultrasound . Journal of Nanoscience and Nanotechnology , 7 : 1 – 6 .
   PubMedGoogle Scholar
• Husseini , GA , Fayoumi , RIE , O’Neill , KL , Rapoport , NY and Pitt , WG . 2000 . DNA damage induced by micellar-delivered doxorubicin and ultrasound: Comet assay study . Cancer Letters , 154 : 211 – 216 .
   PubMed Web of Science ®Google Scholar
• Husseini , GA , Myrup , GD , Pitt , WG , Christensen , DA and Rapoport , NY . 2000 . Factors affecting acoustically triggered release of drugs from polymeric micelles . Journal of Controlled Release , 69 : 43 – 52 .
   PubMed Web of Science ®Google Scholar
• Husseini , GA , Stevenson-Abouelnasr , D , Pitt , WG , Assaleh , KT , Farahat , LO and Fahadi , J . 2010 . Kinetics and thermodynamics of acoustic release of doxorubicin from non-stabilized polymeric micelles . Colloids and Surfaces A: Physicochemical and Engineering Aspects , 359 : 18 – 24 .
   PubMedGoogle Scholar
• Husseini , GA , Pitt , WG , Christensen , DA and Dickinson , DJ . 2009 . Degradation kinetics of stabilized Pluronic micelles under the action of ultrasound . Journal of Controlled Release , 138 : 45 – 48 .
   PubMed Web of Science ®Google Scholar
• Husseini , GA , Abdel-Jabbar , NM , Mjalli , FS , Pitt , WG and Al-Mousa , A . 2011 . Optimizing the use of ultrasound to deliver chemotherapeutic agents to cancer cells from polymeric micelles . Journal of the Franklin Institute , 348 : 1276 – 1284 .
   Web of Science ®Google Scholar
• Husseini , GA and Pitt , WG . 2008 . The use of ultrasound and micelles in cancer treatment . Journal of Nanoscience and Nanotechnology , 8 : 2205 – 2215 .
   PubMed Web of Science ®Google Scholar
• Rapoport , N , Gao , Z and Kennedy , A . 2007 . Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy . Journal of the National Cancer Institute , 99 : 1095 – 1106 .
   PubMed Web of Science ®Google Scholar
• Marin , A , Muniruzzaman , M and Rapoport , N . 2001 . Acoustic activation of drug delivery from polymeric micelles: Effect of pulsed ultrasound . Journal of Controlled Release , 71 : 239 – 249 .
   PubMed Web of Science ®Google Scholar
• Smith , DA , Porter , TM , Martinez , J , Huang , S , MacDonald , RC , McPherson , DD and Holland , CK . 2007 . Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound . Ultrasound in Medicine and Biology , 33 : 797 – 809 .
   PubMed Web of Science ®Google Scholar
• Sukhorukov , GB , Rogach , AL , Garstka , M , Springer , S , Parak , WJ , Munoz-Javier , A , Kreft , O , Skirtach , AG , Susha , AS , Ramaye , Y , Palankar , R and Winterhalter , M . 2007 . Multifunctionalized polymer microcapsules: novel tools for biological and pharmacological applications . Small , 3 : 944 – 955 .
   PubMed Web of Science ®Google Scholar
• Hong , G , Yuan , R , Liang , B , Shen , J , Yang , X and Shuai , X . 2008 . Folate-functionalized polymeric micelle as hepatic carcinoma-targeted, MRI-ultrasensitive delivery system of antitumor drugs . Biomedical Microdevices , 10 : 693 – 700 .
   PubMed Web of Science ®Google Scholar
• Ai , H , Flask , C , Weinberg , B , Shuai , XT , Pagel , MD , Farrell , JD and Gao , JM . 2005 . Magnetite-loaded polymeric micelles as ultrasensitive magnetic-resonance probes . Advanced Materials , 17 : 1949 – 1952 .
   Web of Science ®Google Scholar
• Gang , J , Park , SB , Hyung , W , Choi , EH , Wen , J , Kim , HS , Shul , YG , Haam , S and Song , SY . 2007 . Magnetic poly epsilon-caprolactone nanoparticles containing Fe3O4 and gemcitabine enhance anti-tumor effect in pancreatic cancer xenograft mouse model . Journal of Drug Targeting , 15 : 445 – 453 .
   PubMed Web of Science ®Google Scholar
• Lu , J , Ma , S , Sun , J , Xia , C and Liu , C . 2009 . Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging . Biomaterials , 30 : 2919 – 2928 .
   PubMed Web of Science ®Google Scholar
• Guthi , JS , Yang , SG , Huang , G , Li , S , Khemtong , C , Kessinger , CW , Peyton , M , Minna , JD , Brown , KC and Gao , J . 2009 . MRI-visible micellar nanomedicine for targeted drug delivery to lung cancer cells . Molecular Pharmaceutics , 7 : 32 – 40 .
   Web of Science ®Google Scholar
• Dai , S , Ravi , P and Tam , KC . 2009 . Thermo- and photo-responsive polymeric systems . Soft Matter , 5 : 2513 – 2533 .
   Web of Science ®Google Scholar
• Kumar , GS and Neckers , DC . 1989 . Photochemistry of azobenzene-containing polymers . Chemical Reviews , 89 : 1915 – 1925 .
   Web of Science ®Google Scholar
• Irie , M . 1990 . Photoresponsive polymers . Advances in Polymer Science , 94 : 27 – 67 .
   Web of Science ®Google Scholar
• Natansohn , A and Rochon , P . 2002 . Photoinduced motions in azo-containing polymers . Chemical Reviews , 102 : 4139 – 4175 .
   PubMed Web of Science ®Google Scholar
• Alvarez-Lorenzo , C , Bromberg , L and Concheiro , A . 2009 . Light-sensitive intelligent drug delivery systems . Photochemistry and Photobiology , 85 : 848 – 860 .
   PubMed Web of Science ®Google Scholar
• Yu , H and Kobayashi , T . 2010 . Photoresponsive block copolymers containing azobenzenes and other chromophores . Molecules , 15 : 570 – 603 .
   PubMed Web of Science ®Google Scholar
• Babin , J , Lepage , M and Zhao , Y . 2008 . Decoration of shell cross-linked reverse polymer micelles using ATRP: A new route to stimuli-responsive nanoparticles . Macromolecules , 41 : 1246 – 1253 .
   Web of Science ®Google Scholar
• Jiang , J , Tong , X and Zhao , Y . 2005 . A new design for light-breakable polymer micelles . Journal of the American Chemical Society , 127 : 8290 – 8291 .
   PubMed Web of Science ®Google Scholar
• Jiang , J , Tong , X , Morris , D and Zhao , Y . 2006 . Toward photocontrolled release using light-dissociable block copolymer micelles . Macromolecules , 39 : 4633 – 4640 .
   Web of Science ®Google Scholar
• Xie , Z , Hu , X , Chen , X , Mo , G , Sun , J and Jing , X . 2009 . A novel biodegradable and light-breakable diblock copolymer micelle for drug delivery . Advanced Engineering Materials , 11 : B7 – B11 .
   Google Scholar
• Tong , X , Wang , G , Soldera , A and Zhao , Y . 2005 . How can azobenzene block copolymer vesicles be dissociated and reformed by light? . Journal of Physical Chemistry B , 109 : 20281 – 20287 .
   PubMed Web of Science ®Google Scholar
• Klaikherd , A , Nagamani , C and Thayumanavan , S . 2009 . Multi-stimuli sensitive amphiphilic block copolymer assemblies . Journal of the American Chemical Society , 131 : 4830 – 4838 .
   PubMed Web of Science ®Google Scholar
• Bajpai , A , Shulka , S , Bhanu , S and Kankane , S . 2008 . Responsive polymers in controlled drug delivery . Progress in Polymer Science , 33 : 1088 – 1118 .
   Web of Science ®Google Scholar
• Jin , Q , Lv , LP , Liu , GY , Xu , JP and Ji , J . 2010 . Phenylboronic acid as a sugar- and pH-responsive trigger to tune the multiple micellization of thermo-responsive block copolymer . Polymer , 51 : 3068 – 3074 .
   Web of Science ®Google Scholar
• Carstens , MG , Nostrum , CF , Verrijk , R , De Leede , LGJ , Crommelin , DJA and Hennink , WE . 2008 . A mechanistic study on the chemical and enzymatic degradation of PEG-oligo(ϵ-caprolactone) micelles . Journal of Pharmaceutical Sciences , 97 : 506 – 518 .
   PubMed Web of Science ®Google Scholar
• Torchilin , V . 2009 . Multifunctional and stimuli-sensitive pharmaceutical nanocarriers . European Journal of Pharmaceutics and Biopharmaceutics , 71 : 431 – 444 .
   PubMed Web of Science ®Google Scholar
• Roy , D , Cambre , JN and Sumerlin , BS . 2010 . Future perspectives and recent advances in stimuli-responsive materials . Progress in Polymer Science , 35 : 278 – 301 .
   Web of Science ®Google Scholar
• Vinogradov , S , Batrakova , E , Li , S and Kabanov , A . 1999 . Polyion complex micelles with protein-modified corona for receptor-mediated delivery of oligonucleotides into cells . Bioconjugate Chemistry , 10 : 851 – 860 .
   PubMed Web of Science ®Google Scholar
• Nagasaki , Y , Yasugi , K , Yamamoto , Y , Harada , A and Kataoka , K . 2001 . Sugar-installed block copolymer micelles: Their preparation and specific interaction with lectin molecules . Biomacromolecules , 2 : 1067 – 1070 .
   PubMed Web of Science ®Google Scholar
• Leamon , CP , Weigl , D and Hendren , RW . 1999 . Folate copolymer-mediated transfection of cultured cells . Bioconjugate Chemistry , 10 : 947 – 957 .
   PubMed Web of Science ®Google Scholar
• Xiong , XB , Mahmud , A , Uludag , H and Lavasanifar , A . 2007 . Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene oxide)-b-poly(ϵ-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells . Biomacromolecules , 8 : 874 – 884 .
   PubMed Web of Science ®Google Scholar
• Sawant , RR , Sawant , RM and Torchilin , VP . 2008 . Mixed PEG–PE/vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: Improved drug solubilization and enhanced in vitro cytotoxicity . European Journal of Pharmaceutics and Biopharmaceutics , 70 : 51 – 57 .
   PubMed Web of Science ®Google Scholar
• Lee , ES , Na , K and Bae , YH . 2005 . Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor . Journal of Controlled Release , 103 : 405 – 418 .
   PubMed Web of Science ®Google Scholar
• Gao , Z , Lukyanov , AN , Chakilam , AR and Torchilin , VP . 2003 . PEG-PE/phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing . Journal of Drug Targeting , 11 : 87 – 92 .
   PubMed Web of Science ®Google Scholar
• Goto , M , Yura , H , Chang , CW , Kobayashi , A , Shinoda , T , Maeda , A , Kojima , S , Kobayashi , K and Akaike , TJ . 1994 . Lactose-carrying polystyrene as a drug carrier-investigation of body distribution to parenchymal liver-cells using I-125 labeled lactose-carrying polystyrene . Journal of Controlled Release , 28 : 223 – 233 .
   Web of Science ®Google Scholar
• Dwek , RA . 1996 . Glycobiology: toward understanding the function of sugars . Chemical Reviews , 96 : 683 – 720 .
   PubMed Web of Science ®Google Scholar
• Mammen , M , Choi , SK and Whitesides , GM . 1998 . Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors . Angewandte Chemie (International Edition in English) , 37 : 2754 – 2794 .
   Google Scholar
• Elwood , PC . 1989 . Molecular cloning and characterization of the human folate-binding protein cDNA from placenta and malignant tissue culture (KB) cells . Journal of Biological Chemistry , 264 : 14893 – 14901 .
   PubMed Web of Science ®Google Scholar
• Kim , SH , Jeong , JH , Mok , H , Lee , SH , Kim , SW and Park , TG . 2007 . Folate receptor targeted delivery of polyelectrolyte complex micelles prepared from ODN-PEG-folate conjugate and cationic lipids . Biotechnology Progress , 23 : 232 – 237 .
   PubMed Web of Science ®Google Scholar
• Kim , D , Lee , ES , Oh , KT , Gao , ZG and Bae , YH . 2008 . Doxorubicin-loaded polymeric micelle overcomes multidrug resistance of cancer by double-targeting folate receptor and early endosomal pH . Small , 4 : 2043 – 2050 .
   PubMed Web of Science ®Google Scholar
• Mi , Y , Liu , Y and Feng , SS . 2011 . Formulation of Docetaxel by folic acid-conjugated D-a-tocopheryl polyethylene glycol succinate 2000 (Vitamin E TPGS2k) micelles for targeted and synergistic chemotherapy . Biomaterials , 32 : 4058 – 4066 .
   PubMed Web of Science ®Google Scholar
• Prabaharan , M , Grailer , JJ , Pilla , S , Steeber , DA and Gong , S . 2009 . Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery . Biomaterials , 30 : 5757 – 5766 .
   PubMed Web of Science ®Google Scholar
• Yang , X , Deng , W , Fu , L , Blanco , E , Gao , J , Quan , D and Shuai , X . 2008 . Folate-functionalized polymeric micelles for tumor targeted delivery of a potent multidrug-resistance modulator FG020326 . Journal of Biomedical Materials Research , 86A : 48 – 60 .
   Google Scholar
• Zhua , H , Liu , F , Guo , J , Xue , J , Qian , Z and Gu , Y . 2011 . Folate-modified chitosan micelles with enhanced tumor targeting evaluated by near infrared imaging system . Carbohydrate Polymers , 86 : 1118 – 1129 .
   Google Scholar
• Bae , Y , Nishiyama , N and Kataoka , K . 2007 . In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments . Bioconjugate Chemistry , 18 : 1131 – 1139 .
   PubMed Web of Science ®Google Scholar
• Musacchio , T , Laquintan , V , Latrof , A , Trapani , G and Torchilin , VP . 2009 . PEG-PE micelles loaded with paclitaxel and surface-modified by a PBR-ligand: Synergistic anticancer effect . Molecular Pharmaceutics , 6 : 468 – 479 .
   PubMed Web of Science ®Google Scholar
• Wang , Y , Yang , T , Wang , X , Dai , W , Wang , J , Zhang , X , Li , Z and Zhang , Q . 2011 . Materializing sequential killing of tumor vasculature and tumor cells via targeted polymeric micelle system . Journal of Controlled Release , 149 : 299 – 306 .
   PubMed Web of Science ®Google Scholar
• Wilson , BC . 2002 . Photodynamic therapy for cancer: Principles . Canadian Journal of Gastroenterology , 16 : 393 – 396 .
   PubMed Web of Science ®Google Scholar
• Dougherty , TJ , Gomer , CJ , Henderson , BW , Jori , G , Kessel , D , Korbelik , M , Moan , J and Peng , Q . 1998 . Photodynamic therapy . Journal of the National Cancer Institute , 90 : 889 – 905 .
   PubMed Web of Science ®Google Scholar
• Dolmans , DE , Fukumura , D and Jain , RK . 2003 . Photodynamic therapy for cancer . Nature Reviews Cancer , 3 : 380 – 387 .
   PubMed Web of Science ®Google Scholar
• Bechet , D , Couleaud , P , Frochot , C , Viriot , ML , Guillemin , F and Barberi-Heyob , M . 2008 . Nanoparticles as vehicles for delivery of photodynamic therapy agents . Trends in Biotechnology , 26 : 612 – 621 .
   PubMed Web of Science ®Google Scholar
• Meisel , P and Kocher , T . 2005 . Photodynamic therapy for periodontal diseases: state of the art . Journal of Photochemistry and Photobiology B: Biology , 79 : 159 – 170 .
   PubMed Web of Science ®Google Scholar
• Demidova , TN and Hamblin , MR . 2004 . Photodynamic therapy targeted to pathogens . International Journal of Immunopathology and Pharmacology , 17 : 245 – 254 .
   PubMed Web of Science ®Google Scholar
• Chen , JX , Wang , HY , Li , C , Han , K , Zhang , XZ and Zhuo , RX . 2011 . Construction of surfactant-like tetra-tail amphiphilic peptide with RGD ligand for encapsulation of porphyrin for photodynamic therapy . Biomaterials , 32 : 1678 – 1684 .
   PubMed Web of Science ®Google Scholar
• Taillefer , J , Jones , MC , Brasseur , N , Lier , JE and Leroux , JC . 2000 . Preparation and characterization of pH-responsive polymeric micelles for the delivery of photosensitizing anticancer drugs . Journal of Pharmaceutical Sciences , 89 : 52 – 62 .
   PubMed Web of Science ®Google Scholar
• Garrec , DL , Taillefer , J , Lier , JEV , Lenaerts , V and Leroux , JC . 2002 . Optimizing pH-responsive polymeric micelles for drug delivery in a cancer photodynamic therapy model . Journal of Drug Targeting , 10 : 429 – 437 .
   PubMedGoogle Scholar
• Sibata , MN , Tedesco , AC and Marchetti , JM . 2004 . Photophysicals and photochemicals studies of zinc(II) phthalocyanine in long time circulation micelles for photodynamic therapy use . European Journal of Pharmaceutical Sciences , 23 : 131 – 138 .
   PubMed Web of Science ®Google Scholar
• Master , AM , Rodriguez , ME , Kenney , ME , Oleinick , NL and Gupta , AS . 2010 . Delivery of the photosensitizer Pc 4 in PEG–PCL micelles for in vitro PDT studies . Journal of Pharmaceutical Sciences , 99 : 2386 – 2398 .
   PubMed Web of Science ®Google Scholar
• Hioka , N , Chowdhary , RK , Chansarkar , N , Delmarre , D , Sternberg , E and Dolphin , D . 2002 . Studies of a benzoporphyrin derivative with Pluronics . Canadian Journal of Chemistry , 80 : 1321 – 1326 .
   Google Scholar
• Li , B , Moriyama , EH , Li , F , Jarvi , MT , Allen , C and Wilson , BC . 2007 . Diblock copolymer micelles deliver hydrophobic protoporphyrin ix for photodynamic therapy . Photochemistry and Photobiology , 83 : 1505 – 1512 .
   PubMed Web of Science ®Google Scholar