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Research Article

Identification of a High-Molecular-Weight Glycoconjugate from a Uruguayan Plant that Binds to the Tumor-Associated Tn Antigen

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Pages 26-32 | Accepted 08 Oct 2004, Published online: 07 Oct 2008

References

  • Babino A, Oppezzo P, Bianco S, Barrios E, Berois N, Navarrete H, Osinaga E. (2000): Tn antigen is a pre-cancerous biomarker in breast tissue and serum in N.-nitrosomethylurea-induced rat mammary carcinogenesis. Int J Cancer 86, 753–759. [PUBMED], [INFOTRIEVE]
  • Babino A, Tello D, Rojas A, Bay S, Osinaga E., Alzari PM. (2003): The crystal structure of a plant lectin in complex with the Tn antigen. FEBS Lett 536, 106–110. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Dausset J, Moullec J, Bernard J. (1959): Acquired hemolytic anemia with polyagglutinability of red blood cells due to a new factor present in normal human serum (anti-Tn). Blood 14, 1079–1093. [PUBMED], [INFOTRIEVE]
  • Franco Fraguas L, Plá A, Ferreira F, Massaldi H, Suárez N, Batista-Viera F. (2003): Preparative purification of soybean agglutinin by affinity chromatography and its immobilization for polysaccharide isolation. J Chromatogr B 790, 365–372. [CROSSREF]
  • Hakomori S. (1989): Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv Cancer Res 52, 257–331. [PUBMED], [INFOTRIEVE]
  • Hansen JES, Nielsen C, Arendrup M, Olofsson S, Mathiesen L, Nielsen J, Clausen H. (1991): Broadly neutralizing antibodies targeted to mucin-type carbohydrate epitopes of human immunodeficiency virus. J Virol 65, 6461–6467. [PUBMED], [INFOTRIEVE], [CSA]
  • Laemmli U. (1970): Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 227, 680–685. [PUBMED], [INFOTRIEVE]
  • Medeiros A, Bianchi S, Calvete JJ, Balter H, Bay S, Robles A, Cantacuzène D, Nimtz M, Alzari PM, Osinaga E. (2000): Biochemical and functional characterization of the Tn-specific lectin from Salvia sclarea. seeds. Eur J Biochem 267, 1434–1440. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Muñoz J, Ross P, Cracco P. (1993): Flora indígena del Uruguay. Montevideo, Uruguay, Editorial Agropecuaria Hemisferio Sur, pp. 17–29.
  • Nowak TP, Haywood PL, Barondes SH. (1976): Developmentally regulated lectin in embryonic chick muscle and a myogenic cell line. Biochem Biophys Res Commun 68, 650–657. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Osinaga E, Tello D, Batthyany C, Bianchet M, Tavares G, Durán R, Cerveñansky C, Camoin L, Roseto A, Alzari P. (1997): Amino acid sequence and three-dimensional structure of the Tn-specific isolectin B4 from Vicia villosa.. FEBS Lett 412, 190–196. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Osinaga E, Bay S, Tello D, Babino A, Pritsch O, Assemat K, Cantacuzene D, Nakada H, Alzari P. (2000): Analysis of the fine specificity of Tn-binding proteins using synthetic glycopeptide epitopes and a biosensor based on surface plasmon resonance spectrospcopy. FEBS Lett 469, 24–28. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Pancino G, Osinaga E, Vorauher W, Kakouche A, Mistro D, Charpin C, Roseto A. (1990): Production of a monoclonal antibody as immunohistochemical marker on paraffin embedded tissues using a new immunization method. Hybridoma 9, 389–395. [PUBMED], [INFOTRIEVE], [CSA]
  • Pancino G, Osinaga E, Charpin C, Mistro D, Barque JPh, Roseto A. (1991): Purification and characterization of a breast-cancer-associated glycoprotein not expressed in normal breast and identified by monoclonal antibody 83D4. Br J Cancer 63, 390–398. [PUBMED], [INFOTRIEVE]
  • Plá A, Alonso E, Batista-Viera F, Franco Fraguas L. (2003): Screening for carbohydrate-binding proteins in Uruguayan plants. Braz J Med Biol Res 36, 851–860. [CSA]
  • Puri K, Gopalakrishnan B, Surolia A. (1992): Carbohydrate binding specificity of the Tn-antigen binding lectin from Vicia villosa. seeds (VVLB4). FEBS Lett 312, 208–212. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Schlepper-Schafer J, Springer G. (1989): Carcinoma auto-antigens T and Tn and their cleavage products interact with Gal/GalNAc-specific receptors on rat Kupffer cells and hepatocytes. Biochim Biophys Acta 1013, 266–272. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Smith PK, Khron RI, Hermanson GF, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klent DC. (1985): Measurement of protein using bicinchoninic acid. Anal Biochem 150, 76–85. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Springer GF. (1995): T and Tn pancarcinoma markers: Autoantigenic adhesion molecules in pathogenesis, prebiopsy carcinoma-detection, and long-term breast carcinoma immunotherapy. Crit Rev Oncog 6, 57–85. [PUBMED], [INFOTRIEVE], [CSA]
  • Tettamanti G, W Pigman. (1968): Purification and characterization of bovine and ovine submaxillary mucin. Arch Biochem Biophys 124, 41–50. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Wang H, Ng TB, Ooia VEC, Liu WK. (2000): Efects of lectins with different carbohydrate-binding specificities on hepatoma, choriocarcinoma, melanoma and osteosarcoma cell lines. Int J Biochem Cell Biol 32, 365–372. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Wu A, Wu J, Chen Y-Y, Song S-C, Kabat E. (1999): Further characterization of the combining sites of Bandeirae (Griffonia) simplicifolia. lectin-I, isolectin A4. Glycobiology 9, 1161–1170. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]

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