Immunostimulant activity of the extracts and bioactives of the fruits of Morinda citrifolia

References

• Abbott I, Shimazu C (1985): The geographical origin of the plants most commonly used for medicine by Hawaiians. J Ethnopharmacol 14: 213–222.
   PubMed Web of Science ®Google Scholar
• Akbay P, Basaran A, Undeger U, Basaran N (2003): In vitro immunomodulatory activity of flavanoid glycosides from Urtica dioica L. Phytother Res 17: 34–37.
   PubMed Web of Science ®Google Scholar
• Bhandari C (1985): Vanaushadhi Chandroday, An Encyclopedia of Indian Botanies and Herbs (Part I), Varanasi, Chaukhambha Sanskrit Samsthan, pp. 123.
   Google Scholar
• Bhattacharjee R, Akira S (2005): Toll-like receptor signaling: Emerging opportunities in human diseases and medicine. Curr Immunol Rev 1: 81–90.
   Google Scholar
• Brain K, Turner T (1975): The Practical Evaluation of Phytopharmaceuticals. Bristol, Wright Scientechnica, p. 106.
   Google Scholar
• Burger R, Torres A, Warren R, Caldwell V, Hughes B (1997): Echinacea-induced cytokine production by human macrophages. Int J Immunopharmacol 19: 371–379.
   PubMed Web of Science ®Google Scholar
• Capsoni F, Minonzio F, Venegoni E, Ongari AM, Meroni PL, Guidi G, Zanussi C (1988): In vitro and ex vivo effect of RU41740 on human polymorphonuclear leukocyte function. Int J Immunopharmacol 16: 121–133.
   Google Scholar
• Chen X, Hu Z, Yang X, Huang M, Gao Y, Tang W, Chan S, Dai X, Ye J, Ho P, Duan W, Yang H, Zhu Y, Zhou S (2006): Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer. Int Immunopharmacol 6: 499–508.
   PubMed Web of Science ®Google Scholar
• Chintalwar G, Jain A, Sipahimalani A, Banerji A, Sumariwala P, Ramakrishnan R, Sainis K (1999): An immunologically active arabinogalactan from Tinospora cordifolia. Phytochemistry 52: 1089–1093.
   PubMed Web of Science ®Google Scholar
• Cruse J, Lewis R (1999): Cytokines. In: Atlas of Immunology. New York, CRC Press, pp. 185–191.
   Google Scholar
• Daswani B, Yegnanarayan R (2002): Immunomodulatory activity of Septilin, a polyherbal preparation. Phytother Res 16: 162–165.
   PubMed Web of Science ®Google Scholar
• DerMarderasian (1999): Morinda. In: Guide to Popular Natural Products, USA, Facts and Comparisons Publishing Group, p. 160.
   Google Scholar
• Dewitt S, Hallet M (2002): Cytosolic free Ca2+ changes and calpain activation are required for β integrin-accelerated phagocytosis by human neutrophils. J Cell Biol 159: 181–189.
   PubMed Web of Science ®Google Scholar
• Eeiichi F (2003): Anti-cancer activity of Noni fruit juice against tumors in mice. Proceedings of the 2002 Hawaii Noni Conference, University of Hawaii at Manoa, College of Tropical Agriculture and Human Resources, pp. 2–3.
   Google Scholar
• Elkins R (1998): Hawaiian noni (Morinda citrifolia), Pleasant Grove, UT, Woodland Publishing, pp. 5–27.
   Google Scholar
• Farine J, Lagal L, Moreteau B, Quere J (1996): Volatile components of ripe fruits of Morinda citrifolia and their effects on Drosophila. Phytochemistry 41: 433–438.
   Web of Science ®Google Scholar
• Fulton S, Reba S, Martin T, Boom W (2002): Neutrophil-mediated mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice. Infect Immun 70: 5322–5327.
   PubMed Web of Science ®Google Scholar
• Gisbergen K, Geijtenbeek, Kook Y (2005): Close encounters of neutrophils and DCs. Trends Immunol 26: 626–631.
   PubMed Web of Science ®Google Scholar
• Goodrich M, McGee D (1999): Effect of intestinal epithelial cell cytokines on mucosal B-cell IgA secretion: Enhancing effect of epithelial-derived IL-6 but not TGF-beta on IgA+ B cells Immunol Lett 67: 11–14.
   PubMed Web of Science ®Google Scholar
• Guangming L, Ann B, Wei-Ya M, Shengmin S, Chi-Tang H, Zigang D (2001): Two novel glycosides from the fruits of Morinda citrifolia (Noni) inhibit AP-1 transactivation and cell transformation in the mouse epidermal JB6 cell line. Cancer Res 61: 5749–5756.
   PubMed Web of Science ®Google Scholar
• Hirazumi A, Furusawa E, Chou S, Hokama Y (1994): Anticancer activity of Morinda citrifolia on intraperitoneally implanted Lewis lung carcinoma in syngenic mice. Proc West Pharmacol Soc 37: 145–146.
   PubMedGoogle Scholar
• Hirazumi A, Furusawa E, Chou S, Hokama Y (1996): Immunomodulation contributes to the anticancer activity of Morinda citrifolia (noni) fruit juice. Proc West Pharmacol Soc 39: 7–9.
   PubMedGoogle Scholar
• Hirazumi A, Furusawa E (1999): An immunomodulatory polysaccharide-rich substance from the fruit juice of Morinda citrifolia (Noni) with antitumor activity. Phytother Res 13: 692–695.
   PubMed Web of Science ®Google Scholar
• Ichim C (2005): Revisiting immunosurveillance and immunostimulation: Implications for cancer immunotherapy. J Transl Med 3: 8–21.
   PubMed Web of Science ®Google Scholar
• Iwu M (1993): Handbook of African Medicinal Plants, Tokyo, CRC Press, pp. 209–210.
   Google Scholar
• Kamiya K, Tanaka Y, Umar M, Satake T (2005): New anthraquinone and iridoid from the fruits of Morinda citrifolia. Chem Pharm Bull 53: 1597–1599.
   PubMed Web of Science ®Google Scholar
• Kirtikar K, Basu B (1975): Indian Medicinal Plants, Vol. 2, Delhi, Periodical Expert Book Agency, p. 1295.
   Google Scholar
• Kobayashi S, Voyich J, Burlak C, DeLeo F (2005): Neutrophils in the innate immune response. Arch Immunol Ther Exp 53: 505–517.
   PubMed Web of Science ®Google Scholar
• Krishnamoorthy N, Reddy G (1970): Preliminary phytochemical and pharmacological study of Morinda citrifolia Linn. Antiseptic 67: 167–171.
   Google Scholar
• Lagranderie M, Balazuc A, Deriaud E, Leclerc C, Gheorghiu M (1996): Comparison of immune responses of mice immunized with five different Mycobacterium bovis BCG strains. Infect Immun 64: 1–9.
   PubMed Web of Science ®Google Scholar
• Leung M, Liu M, Zhu L, Hui Y, Yu B, Fung K (2004): Chemical and biological characterization of a polysaccharide biological response modifier from Aloe vera L. var. chinensis (Haw) Berg. Glycobiology 14: 501–510.
   PubMed Web of Science ®Google Scholar
• McClatchey W (2002): From Polynesian healers to health food stores: Changing perspectives of Morinda citrifolia (Rubiaceae). Integrative Cancer Therap 1: 110–120.
   PubMedGoogle Scholar
• Mckoy M, Thomas E, Simon O (2002): Preliminary investigation of the anti-inflammatory properties of an aqueous extract from Morinda citrifolia (Noni). Proc West Pharmacol Soc 45: 76–78.
   PubMedGoogle Scholar
• Nair P, Rodriguez S, Ramachandran R, Alamo A, Melnick S, Escalon R, Garcia P, Wnuck S, Ramachandran C (2004): Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. Int Immunopharmacol 4: 1645–1659.
   PubMed Web of Science ®Google Scholar
• Nandhasri P, Pawa K, Kaewtubtim J, Jeamchanya C, Jansom C, Sattaponpun C (2005): Nutraceutical properties of Thai “Yor” Morinda citrifolia and “Noni” juice extract. Songklanakarin J Sci Technol 27: 579–586.
   Google Scholar
• Kishimoto T (1992): Interleukin-6 and its receptor; from cloning to clinic. Int Arch Allergy Immunol 99: 172–177.
   PubMed Web of Science ®Google Scholar
• Palu A, Kim A, West B, Deng S, Jensen J, White L (2008): The effects of Morinda citrifolia L. (noni) on the immune system: Its molecular mechanisms of action. J Ethnopharmacol 115: 502–506.
   PubMed Web of Science ®Google Scholar
• Pedraza-Sanchez S, Gonzalez-Hernandez Y, Escobar-Gutierrez A, Ramachandra L (2006): The immunostimulant RU41740 from Klebsiella pneumoniae activates human cells in whole blood to potentially stimulate innate and adaptive immune responses. Int Immunopharmacol 6: 635–646.
   PubMed Web of Science ®Google Scholar
• Singh J, Tiwari R (1976): Flavone glycosides from the flowers of Morinda citrifolia. J Indian Chem Soc 53: 424.
   Web of Science ®Google Scholar
• Takashima J, Ikeda Y, Komiyama K, Hayashi M, Kishida A, Ohsaki A (2007): New constituents from the leaves of Morinda citrifolia. Planta Med 55: 343–345.
   Google Scholar
• Taub D, Anver M, Oppenheim J, Longo D, Murphy W (1996): T-lymphocyte recruitment by interleukin 8 (IL-8). J Clin Invest 97: 1931–1941.
   PubMed Web of Science ®Google Scholar
• Thatte U, Kulkarni M, Dahanukar S (1992): Immunotherapeutic modification of Escherichia coli peritonitis and bacteremia by Tinospora cordifolia. J Postgrad Med 38: 13–16.
   PubMedGoogle Scholar
• Tiwari R, Singh J (1977): Structural study of the anthraquinone glycoside from the flowers of Morinda citrifolia. J Indian Chem Soc 54: 429–430.
   Web of Science ®Google Scholar
• Vishin M, Gupta D (1967): Estimation of alkaloids of Kurchi by non-aqueous titration. Indian J Pharm 29: 3–4.
   Google Scholar
• Walsh G (1998): The cytokines: The interferon family, In: Biopharmaceuticals: Biochemistry and Biotechnology. New York, John Wiley, pp. 189–215.
   Google Scholar
• Wang M, West B, Jensen C, Nowicki D, Chen S, Palu A, Andersen G (2002): Morinda citrifolia (Noni): A literature review and recent advances in Noni research. Acta Pharmacol Sin 23: 1127–1141.
   PubMed Web of Science ®Google Scholar
• Wang M, Kikuzaki H, Jin Y, Nakatani N, Zhu N, Csiszar K, Boyd C, Rosen R, Ghai G, Chi-Tang H (2000): Novel glycosides from Noni (Morinda citrifolia). J Nat Prod 63: 1182–1183.
   PubMed Web of Science ®Google Scholar
• Wang M, Su C (2001): Cancer preventive effect of Morinda citrifolia (Noni). Ann N Y Acad Sci 952: 161–168.
   PubMed Web of Science ®Google Scholar
• Xing L, Remick D (2004): Neutrophils as firemen, production of anti-inflammatory mediators by neutrophils in a mixed cell environment. Cell Immunol 231: 126–132.
   PubMed Web of Science ®Google Scholar
• Zhang C, Huang K (2005): Characteristic immunostimulation by MAP, a polysaccharide isolated from the mucus of the loach, Misgurnus anguillicaudatus. Carbohyd Polymers 59: 75–82.
   Web of Science ®Google Scholar