In vitro cytotoxicity, genotoxicity and antigenotoxicity assessment of Solanum lycocarpum hydroalcoholic extract

References

• Boiteux S, Guillet M. 2004. Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisae. DNA Repair. 3:1–12.
   PubMed Web of Science ®Google Scholar
• Burlinson B, Tice RR, Speit G, Agurell E, Brendler-Schwaab SY, Collins AR, Escobar P, Honmah M, Kumaravel TS, Nakajima M, et al. 2007. Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup. Mutat Res. 627:31–35.
   PubMed Web of Science ®Google Scholar
• Chacon DR, Libera AND, Cintra DEC, Carvalho JCT, Oliveira GA, Maistro EL. 2002. Absence of genotoxic and antigenotoxic effects of a standardized extract of the medicinal plant Solanun melongena on peripheral blood and bone marrow cells of Wistar rats. Cytologia. 67:417–422.
   Google Scholar
• Dall’Agnol R, von Poser GL. 2000. The use of complex polysaccharides in the management of metabolic diseases: the case of Solanum lycocarpum fruits. J Ethnopharmacol. 71:337–341.
   PubMed Web of Science ®Google Scholar
• De Marino S, Festa C, Zollo F, Nini A, Antenucci L, Raimo G, Iorizzi M. 2014. Antioxidant activity and chemical componentes as potential anticancer agents in the olive leaf (Olea europaea L. cv Leccino) decoction. Anticancer Agents Med Chem. 14:1376–1385.
   PubMed Web of Science ®Google Scholar
• Eastmond DA, Tucker JD. 1989. Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody. Environ Mol Mutagen. 13:34–43.
   PubMed Web of Science ®Google Scholar
• Fenech M. 2000. The in vitro micronucleus technique. Mutat Res. 455:81–95.
   PubMed Web of Science ®Google Scholar
• Franken NAP, Rodermond HM, Stap J, Haveman J, Bree CV. 2006. Clonogenic assay of cells in vitro. Nat Protoc. 1:2315–2319.
   PubMed Web of Science ®Google Scholar
• Friedman M, Henika PR. 1992. Absence of genotoxicity of potato alkaloids alpha-chaconine, alpha-solanine and solanidine in the Ames Salmonella and adult and foetal erythrocyte micronucleus assays. Food Chem Toxicol. 30:689–694.
   PubMed Web of Science ®Google Scholar
• Horváthová E, Slamenová D Hlinciková L, Mandal TK, Gábelová A, Collins AR. 1998. The nature and origin of DNA single-strand breaks determined with the comet assay. Mutat Res. 409:163–171.
   PubMed Web of Science ®Google Scholar
• Hu K, Kobayashi H, Dong A. 1999. Antineoplastic agents. III: Steroidal glycosides from Solanum nigrum. Planta Med. 65:35–38.
   PubMed Web of Science ®Google Scholar
• Jafari S, Saeidnia S, Abdollahi M. 2014. Role of natural phenolic compounds in cancer chemoprevention via regulation of the cell cycle. Curr Pharm Biotechnol. 15:409–421.
   PubMed Web of Science ®Google Scholar
• Kaina B. 2004. Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go. Cytogenet Genome Res. 104:77–86.
   PubMed Web of Science ®Google Scholar
• Kehrer JP, Klotz LO. 2015. Free radicals and related reactive species as mediators of tissue injury and disease: implications for health. Crit Rev Toxicol. 45:765–798.
   PubMed Web of Science ®Google Scholar
• Kirsch-Volders M, Sofuni T, Aardema M, Albertini S, Eastmond D, Fenech M, Ishidate MJr, Kirchner S, Lorge E, Morita T, et al. 2003. Report from the in vitro micronucleus assay working group. Mutat Res. 540:153–163.
   PubMed Web of Science ®Google Scholar
• Knasmüller S, Steinkellner H Majer BJ, Nobis EC, Scharf G, Kassie F. 2002. Search for dietary antimutagens and anticarcinogens: methodological aspects and extrapolation problems. Food Chem Toxicol. 40:1051–1062.
   PubMed Web of Science ®Google Scholar
• Landis-Piwowar KR, Iyer NR. 2014. Cancer chemoprevention: current state of the art. Cancer Growth Metastasis. 10:19–25.
   Google Scholar
• Lee KR, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M. 2004. Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells. J Agric Food Chem. 52:2832–2839.
   PubMed Web of Science ®Google Scholar
• Leenders M, Siersema PD, Overvad K, Tjonneland A, Olsen A, Boutron-Ruault MC, Bastide N, Fagherazzi G, Katzke V, Kühn T, et al. 2015. Subtypes of fruit and vegetables, variety in consumption and risk of colon and rectal cancer in the European prospective investigation into cancer and nutrition. Int J Cancer. 137:2705–2714.
   PubMed Web of Science ®Google Scholar
• Lin CN, Chung MI, Gan KH. 1998. Novel antihepatotoxic principles of Solanum incanum. Planta Med. 54:222.
   Google Scholar
• Liochev SI. 2015. Which is the most significant cause of aging? Antioxidants (Basel). 17:793–810.
   Google Scholar
• Liu H, Lightfoot R, Stevens JL. 1996. Activation of heat shock factor by alkylating agents is triggered by glutathione depletion and oxidant of protein thiols. J Biol Chem. 271:4805–4812.
   PubMed Web of Science ®Google Scholar
• Lorenzi H. 1991. Plantas daninhas do Brasil. 2nd ed. Nova Odessa: Plantarum. p. 392.
   Google Scholar
• Lorey S, Porzel A, Ripperger H. 1996. Steroid alkaloid glycosides from Solanum coccineum. Phytochemistry. 41:1633–1635.
   PubMed Web of Science ®Google Scholar
• Luke AM, Chastain PD, Pachkowski BF, Afonin V, Takeda S, Kaufman DG, Swenberg JA, Nakamura J. 2010. Accumulation of true single strand breaks and AP sites in base excision repair deficient cells. Mutat Res. 694:65–71.
   PubMed Web of Science ®Google Scholar
• Maruo VM, Bernardi MM, Spinosa HS. 2003. Toxicological evaluations of long-term consumption of Solanum lycocarpum St. Hill fruits in male and female adult rats . Phytomedicine. 10:48–52.
   PubMed Web of Science ®Google Scholar
• Munari CC, Oliveira PF, Lima IMS, Martins SPL, Costa JC, Bastos JK, Tavares DC. 2012. Evaluation of cytotoxic, genotoxic and antigenotoxic potential of Solanum lycocarpum fruits glicoalkaloid extract in V79 cells. Food Chem Toxicol. 50:3696–3701.
   PubMed Web of Science ®Google Scholar
• Oliveira AC, Endringer DC, Araújo RJ, Brandão MG, Coelho MM. 2003. The starch from Solanum lycocarpum St. Hill. fruit is not a hypoglycemic agent. Braz J Med Biol Res. 36:525–530.
   PubMed Web of Science ®Google Scholar
• Shiu LY, Chang LC, Liang CH, Huang YS, Sheu HM, Kuo KW. 2007. Solamargine induces apoptosis and sensitizes breast cancer cells to cisplatin. Food Chem Toxicol. 45:2155–2164.
   PubMed Web of Science ®Google Scholar
• Shukla S, Meeran SM, Katiyar SK. 2014. Epigenetic regulation by selected dietary phytochemicals in cancer chemoprevention. Cancer Lett. 355:9–17.
   PubMed Web of Science ®Google Scholar
• Siddiqui IA, Adhami VM, Saleem M, Mukhtar H. 2006. Beneficial effects of tea and its polyphenols against prostate cancer. Mol Nutr Food Res. 50:130–143.
   PubMed Web of Science ®Google Scholar
• Singh NP, McCoy MT, Tice RR, Schneider EL. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res. 175:184–191.
   PubMed Web of Science ®Google Scholar
• Tavares DC, Munari CC Araújo MG, Beltrame MC, Furtado MA, Gonçalves CC, Tiossi RF, Bastos JK, Cunha WR, Veneziani RC. 2011. Antimutagenic potential of Solanum lycocarpum against induction of chromosomal aberrations in V79 cells and micronuclei in mice by doxorubicin. Planta Med. 77:1489–1494.
   PubMed Web of Science ®Google Scholar
• Thakur VS, Gupta K, Gupta S. 2012. Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases. Carcinogenesis. 33:377–384.
   PubMed Web of Science ®Google Scholar
• Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. 2007. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol. 39:44–84.
   PubMed Web of Science ®Google Scholar
• Van der Walter B, Zoeteweij JP, Nagelkerke JF. 1996. Alkylation-induced oxidative cell injury of renal proximal tubular cells: involvement of glutathione redox-cycle inhibition. Arch Biochem Biophys. 327:71–80.
   PubMed Web of Science ®Google Scholar
• Waters MD, Brady AL, Stack HF, Brockman HE. 1990. Antimutagenicity profiles for some model compounds. Mutat Res. 38:57–85.
   Web of Science ®Google Scholar
• Wyatt MD, Pittman LP. 2006. Methylating agents and DNA repair responses: methylated bases and sources of strand breaks. Chem Res Toxicol. 19:1580–1594.
   PubMed Web of Science ®Google Scholar
• Yen GC, Chen HY, Peng HH. 2001. Evaluation of the cytotoxicity, mutagenicity and antimutagenicity of emerging edible plants. Food Chem Toxicol. 39:1045–1053.
   PubMed Web of Science ®Google Scholar