Eugenia dysenterica DC. (Myrtaceae) exerts chemopreventive effects against hexavalent chromium-induced damage in vitro and in vivo

References

• Almeida SP, Proença CEB, Sano SM, Ribeiro JF. 1998. Cerrado: espécies vegetais úteis. Brasília, Brazil: Embrapa-Centrode Pesquisa Agropecuáriados Cerrados.
   Google Scholar
• AOAC. 1990. Official methods of analysis of the Association Analytical Chemists. Gaithersburg: Better World Books.
   Google Scholar
• Araújo JR, Gonçalves P, Martel F. 2011. Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines. Nutr Res. 31:77–87.
   PubMed Web of Science ®Google Scholar
• ATSDR. 2012. Toxicological profile for chromium. Atlanta, USA: Department of Health and Human Services, Public Health Service.
   Google Scholar
• Ávila RI, Guerra MT, Borges KAS, Vieira MS, Oliveira Júnior LM, Furtado H, Mota MF, Arruda AF, Valadares MC. 2013. Punica granatum L. protects mice against hexavalent chromium-induced genotoxicity. Braz J Pharm Sci. 49:689–697.
   Web of Science ®Google Scholar
• Bagchi D, Stohs SJ, Downs BW, Bagchi M, Preuss HG. 2002. Cytotoxicity and oxidative mechanisms of different forms of chromium. Toxicology. 180:5–22.
   PubMed Web of Science ®Google Scholar
• Barceloux DG. 1999. Chromium. J Toxicol Clin Toxicol. 37:173–194.
   PubMed Web of Science ®Google Scholar
• Bardin-Mikolajczak A, Lissowska J, Zaridze D, Szeszenia-Dabrowska N, Rudnai P, Fabianova E, Mates D, Navratilova M, Bencko V, Janout V, et al. 2007. Occupation and risk of lung cancer in Central and Eastern Europe: the IARC multi-center case-control study. Cancer Causes Control. 18:645–654.
   PubMed Web of Science ®Google Scholar
• Barrera D, Maldonado PD, Medina-Campos ON, Hernández-Pando R, Ibarra-Rubio ME, Pedraza-Chaverrí J. 2003. HO-1 induction attenuates renal damage and oxidative stress induced by K2Cr2O7. Free Radic Biol Med. 34:1390–1398.
   PubMed Web of Science ®Google Scholar
• Bors W, Michel C. 2002. Chemistry of the antioxidant effect of polyphenols. Ann NY Acad Sci. 957:57–69.
   PubMed Web of Science ®Google Scholar
• Brand-Williams W, Cuvelier ME, Berset C. 1995. Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci Technol. 28:25–30.
   Web of Science ®Google Scholar
• Cardoso LM, Martino HSD, Moreira AVB, Ribeiro SMR, Pinheiro-Sant'Ana HM. 2011. Cagaita (Eugenia dysenterica DC.) of the Cerrado of Minas Gerais, Brazil: physical and chemical characterization, carotenoids and vitamins. Food Res Int. 44:2151–2154.
   Web of Science ®Google Scholar
• Cecílio AB, Faria DB, Oliveira PC, Caldas S, de Oliveira DA, Sobral ME, Duarte MG, Moreira CP, Silva CG, de Amaral VL. 2012. Screening of Brazilian medicinal plants for antiviral activity against rotavirus. J Ethnopharmacol. 141:975–981.
   PubMed Web of Science ®Google Scholar
• Couto RO, Valgas AB, Bara MTF, Paula JR. 2009. Physico-chemical characterization of Eugenia dysenterica DC. (Myrtaceae) leaves powder. Rev Eletrôn Farm. VI:59–69.
   Google Scholar
• Couto RO, Araújo RR, Tacon LA, Conceição EC, Bara MTF, Paula JR, Freitas LAP. 2011. Development of a phytopharmaceutical intermediate product via spray drying. Drying Technol. 29:709–718.
   Web of Science ®Google Scholar
• Couto RO, Martins FS, Chaul LT, Conceição EC, Freitas LAP, Bara MTF, Paula JR. 2012. Spray drying of Eugenia dysenterica extract: effects of in-process parameters on product quality. Rev Bras Farmacogn. 23:115–123.
   Google Scholar
• Couto RO, Martins FS, Chaul LT, Conceição EC, Freitas LAP, Bara MTF, Paula JR. 2013. Spray drying of Eugenia dysenterica extract: effects of in-process parameters on product quality. Braz J Pharmacogn. 23:115–123.
   Web of Science ®Google Scholar
• Deb DD, Parimala G, Devi SS, Chakrabarti T. 2012. Role of Carum copticum seeds in modulating chromium-induced toxicity on human bronchial epithelial cells and human peripheral blood lymphocytes. Exp Toxicol Pathol. 64:889–897.
   PubMed Web of Science ®Google Scholar
• Ding Y, Zhang B, Zhou K, Chen M, Wang M, Jia Y, Song Y, Li Y, Wen A. 2014. Dietary ellagic acid improves oxidant-induced endothelial dysfunction and atherosclerosis: role of Nrf2 activation. Int J Cardiol. 175:508–514.
   PubMed Web of Science ®Google Scholar
• Elmore S. 2007. Apoptosis: a review of programmed cell death. Toxicol Pathol. 35:495–516.
   PubMed Web of Science ®Google Scholar
• Fariss MW, Chan CB, Patel M, Van Houten B, Orrenius S. 2005. Role of mitochondria in toxic oxidative stress. Mol Interv. 5:94–111.
   PubMed Web of Science ®Google Scholar
• Fatima S, Mahmood R. 2007. Vitamin C attenuates potassium dichromate-induced nephrotoxicity and alterations in renal brush border membrane enzymes and phosphate transport in rats. Clin Chim Acta. 386:94–99.
   PubMed Web of Science ®Google Scholar
• Fernandes TO, Ávila RI, Moura SS, et al. 2015. Campomanesia adamantium (Myrtaceae) fruits protect HepG2 cells against carbon tetrachloride-induced toxicity. Toxicol Rep. 2:184–193.
   PubMed Web of Science ®Google Scholar
• Fraga CG, Oteiza PI. 2011. Dietary flavonoids: role of (−)-epicatechin and related procyanidins in cell signaling. Free Radic Biol Med. 51:813–823.
   PubMed Web of Science ®Google Scholar
• Gonçalves AESS, Lajolo FM, Genovese MI. 2010. Chemical composition and antioxidant/antidiabetic potential of Brazilian native fruits and commercial frozen pulps. J Agric Food Chem. 58:4666–4674.
   PubMed Web of Science ®Google Scholar
• Gunaratnam M, Grant MH. 2004. Damage to F-actin and cell death induced by chromium VI and nickel in primary monolayer cultures of rat hepatocytes. Toxicol In Vitro. 18:245–253.
   PubMed Web of Science ®Google Scholar
• Hubrecht R, Kirkwood J. 2010. The UFAW handbook on the care and management of laboratory and other research animals. England: Wiley-Blackwell.
   Google Scholar
• Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, et al. 1997. An Nrf2/Small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun. 236:313–322.
   PubMed Web of Science ®Google Scholar
• Kähkönen MP, Hopia AI, Vuorela HJ, Rauha JP, Pihlaja K, Kujala TS, Heinonen M. 1999. Antioxidant activity of plant extracts containing phenolic compounds. J Agric Food Chem. 47:3954–3962.
   PubMed Web of Science ®Google Scholar
• Kargacin B, Squibb KS, Cosentino S, Zhitkovich A, Costa M. 1993. Comparison of the uptake and distribution of chromate in rats and mice. Biol Trace Elem Res. 36:307–318.
   Web of Science ®Google Scholar
• Khan MR, Siddiqui S, Parveen K, Javed S, Diwakar S, Siddiqui WA. 2010. Nephroprotective action of tocotrienol-rich fraction (TRF) from palm oil against potassium dichromate (K2Cr2O7)-induced acute renal injury in rats. Chem Biol Interact. 186:228–238.
   PubMed Web of Science ®Google Scholar
• Lima TB, Silva ON, Oliveira JTA, Vasconcelos IM, Scalabrin FB, Rocha TL, Grossi-de-Sá MF, Silva LP, Guadagnin RV, Quirino BF, et al. 2010. Identification of E. dysenterica laxative peptide: a novel strategy in the treatment of chronic constipation and irritable bowel syndrome. Peptides. 31:1426–1433.
   PubMed Web of Science ®Google Scholar
• Lima TB, Silva ON, Silva LP, Rocha TL, Grossi-de-Sá MF, Franco OL. 2011. In vivo effects of cagaita (Eugenia dysenterica, DC.) leaf extracts on diarrhea treatment. Evid Based Complement Alternat Med. 2011:1–10.
   Google Scholar
• Markham KR. 1982. Ultraviolet-visible absorption spectroscopy. In: Techniques of flavonoid identification. London: Academic Press Inc. p. 36–51.
   Google Scholar
• Miller H. 1971. A simplified method for the evaluation of antioxidants. J Am Oil Chem Soc. 48:91.
   Web of Science ®Google Scholar
• Molina-Jijón E, Tapia E, Zazueta C, El Hafidi M, Zatarain-Barrón ZL, Hernández-Pando R, Medina-Campos ON, Zarco-Márquez G, Torres I, Pedraza-Chaverri J. 2011. Curcumin prevents Cr(VI)-induced renal oxidant damage by a mitochondrial pathway. Free Radic Biol Med. 51:1543–1557.
   PubMed Web of Science ®Google Scholar
• Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 65:55–63.
   PubMed Web of Science ®Google Scholar
• Mota MF, Benfica PL, Batista AC, Martins FS, de Paula JR, Valadares MC. 2012. Investigation of Ehrlich ascites tumor cell death mechanisms induced by Synadenium umbellatum Pax. J Ethnopharmacol. 139:319–329.
   PubMed Web of Science ®Google Scholar
• Murakami A, Ohnishi K. 2012. Target molecules of food phytochemicals: food science bound for the next dimension. Food Funct. 3:462–476.
   PubMed Web of Science ®Google Scholar
• O’Brien TJ, Ceryak S, Patierno SR. 2003. Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms. Mutat Res. 533:3–36.
   PubMed Web of Science ®Google Scholar
• Parveen K, Khan MR, Siddiqui WA. 2009. Pycnogenol prevents potassium dichromate K2Cr2O7-induced oxidative damage and nephrotoxicity in rats. Chem Biol Interact. 181:343–350.
   PubMed Web of Science ®Google Scholar
• Pietta P. 2000. Flavonoids as antioxidants. J Nat Prod. 63:1035–1042.
   PubMed Web of Science ®Google Scholar
• Prado LC, Silva DB, de Oliveira-Silva GL, Hiraki KR, Canabrava HA, Bispo-da-Silva LB. 2014. The gastroprotective effects of Eugenia dysenterica (Myrtaceae) leaf extract: the possible role of condensed tannins. Biol Pharm Bull. 37:722–730.
   PubMed Web of Science ®Google Scholar
• Rafael AI, Almeida A, Santos P, Parreira I, Madeira VM, Alves R, Cabrita AM, Alpoim MC. 2007. A role for transforming growth factor-beta apoptotic signaling pathway in liver injury induced by ingestion of water contaminated with high levels of Cr(VI). Toxicol Appl Pharmacol. 224:163–173.
   PubMed Web of Science ®Google Scholar
• Roesler R, Malta LG, Carrasco LC, Holanda RB, Sousa CAS, Pastore GM. 2007. Antioxidant activity of cerrado fruits. Food Sci Technol. 27:53–60.
   Google Scholar
• Russo P, Catassi A, Cesario A, Imperatori A, Rotolo N, Fini M, Granone P, Dominioni L. 2005. Molecular mechanisms of hexavalent chromium–induced apoptosis in human bronchoalveolar cells. Am J Respir Cell Mol Biol. 33:489–600.
   Web of Science ®Google Scholar
• Seidler A, Jähnichen S, Hegewald J, Fishta A, Krug O, Rüter L, Strik C, Hallier E, Straube S. 2012. Systematic review and quantification of respiratory cancer risk for occupational exposure to hexavalent chromium. Int Arch Occup Environ Health. 86:943–955.
   PubMed Web of Science ®Google Scholar
• Son Y-O, Hitron JA, Wang X, Chang Q, Pan J, Zhang Z, Liu J, Wang S, Lee JC, Shi X. 2010. Cr(VI) induces mitochondrial-mediated and caspase-dependent apoptosis through reactive oxygen species-mediated p53 activation in JB6 Cl41 cells. Toxicol Appl Pharmacol. 245:226–235.
   PubMed Web of Science ®Google Scholar
• Souza PM, Elias ST, Simeoni LA, de Paula JE, Gomes EN, Fonseca YM, Silva EC, Silveira D, Magalhães PO. 2012a. Plants from Brazilian Cerrado with potent tyrosinase inhibitory activity. PloS One. 7:1–7.
   Google Scholar
• Souza PM, Sales PM, Simeoni LA, Silva EC, Silveira D, Magalhães PO. 2012b. Inhibitory activity of α-amylase and α-glucosidase by plant extracts from the Brazilian Cerrado. Planta Med. 78:393–399.
   PubMed Web of Science ®Google Scholar
• Thangapandiyan S, Miltonprabu S. 2014. Epigallocatechin gallate supplementation protects against renal injury induced by fluoride intoxication in rats: role of Nrf2/HO-1 signaling. Toxicol Rep. 1:12–30.
   Google Scholar
• Urquiaga I, Leighton F. 2000. Plant polyphenol antioxidants and oxidative stress. Biol Res. 33:55–64.
   PubMed Web of Science ®Google Scholar
• Vieira PM, Veronezi E, Silva CR, Chen-Chen L. 2012. Detection of genotoxic, cytotoxic, and protective activities of Eugenia dysenterica DC. (Myrtaceae) in mice. J Med Food. 15:563–567.
   PubMed Web of Science ®Google Scholar
• von Burg R, Liu D. 1993. Chromium and hexavalent chromium. J Appl Toxicol. 13:225–230.
   PubMed Web of Science ®Google Scholar
• Wang X-F, Lou X-M, Shen Y, Xing ML, Xu LH. 2010. Apoptotic-related protein changes induced by hexavalent chromium in mice liver. Environ Toxicol. 25:77–82.
   PubMed Web of Science ®Google Scholar
• Wang L, Gao S, Jiang W, Luo C, Xu M, Bohlin L, Rosendahl M, Huang W. 2014. Antioxidative dietary compounds modulate gene expression associated with apoptosis, DNA repair, inhibition of cell proliferation and migration. Int J Mol Sci. 15:16226–16245.
   PubMed Web of Science ®Google Scholar
• Wilbur S, Ingerman L, Citra M, Osier M, Wohlers D. 2000. Toxicological profile for chromium. Atlanta, USA: Agency for Toxic Substances and Disease Registry.
   Google Scholar
• Wu F, Sun H, Kluz T, et al. 2012. Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro. Toxicol Appl Pharmacol. 258:166–175.
   PubMed Web of Science ®Google Scholar
• Yao P, Nussler A, Liu L, Hao L, Song F, Schirmeier A, Nussler N. 2007. Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. J Hepatol. 47:253–261.
   PubMed Web of Science ®Google Scholar
• Ye J, Wang S, Leonard SS, Sun Y, Butterworth L, Antonini J, Ding M, Rojanasakul Y, Vallyathan V, Castranova V. 1999. Role of reactive oxygen species and p53 in chromium(VI)-induced apoptosis. J Biol Chem. 274:34974–34980.
   PubMed Web of Science ®Google Scholar
• Zhang DD. 2006. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab Rev. 38:769–789.
   PubMed Web of Science ®Google Scholar