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Research Article

Anti-inflammatory and anticancer effects of flavonol glycosides from Diplotaxis harra through GSK3β regulation in intestinal cells

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Pages 124-131 | Received 06 Jun 2016, Accepted 25 Aug 2016, Published online: 22 Sep 2016

References

  • Antunes-Ricardo M, Moreno-García BE, Gutiérrez-Uribe JA, Aráiz-Hernández D, Alvarez MM, Serna-Saldivar SO. 2014. Induction of apoptosis in colon cancer cells treated with isorhamnetin glycosides from Opuntia ficus-indica pads. Plant Foods Hum Nutr. 69:331–336.
  • Atta EM, Hashem AI, Ahmed AM, Elqosy SM, Jasparse M, El-Sharkaw ER. 2011. Phytochemical studies on Diplotaxis harra growing in Sinai. Eur J Chem. 2:535–538.
  • Bellakhdar J. 1997. La pharmacopée marocaine traditionnelle: médecine arabe ancienne et savoirs populaires. Paris: Ibis Press.
  • Bourogaa E, Despeaux M, Jarraya R, Fabre N, Bertrand J, Payrastre L, Demur C, Damak M, Fournié J, El Feki A, et al. 2011 . Hammada scoparia flavonoids and rutin kill adherent and chemoresistant leukemic cells. Leuk Res. 35:1093–1101.
  • Dinkova-Kostova AT. 2012. Chemoprotection against cancer by isothiocyanates: a focus on the animal models and the protective mechanisms. Top Curr Chem. 329:179–201.
  • Falleh H, Msilini N, Oueslati S, Ksouri R, Magne C, Lachaal M, Karray-Bouraoui N. 2013. Diplotaxis harra and Diplotaxis simplex organs: assessment of phenolics and biological activities before and after fractionation. Ind Crops Prod. 45:141–147.
  • Fasano A, Fiorentini C, Donelli G, Uzzau S, Kaper JB, Margaretten K, Ding Z, Guandalini S, Comstock L, Goldblum SE. 1995. Zonula Occludens Toxin (ZOT) modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro. J Clin Invest. 96:710–720.
  • Fini L, Piazzi G, Daoud Y, Selgrad M, Maegawa S, Garcia M, Fogliano V, Romano M, Graziani G, Vitaglione P, et al. 2011. Chemoprevention of intestinal polyps in ApcMin/+ mice fed with western or balanced diets by drinking Annurca apple polyphenol extract. Cancer Prev Res (Phila). 4:907–915.
  • Ghrabi Z. 2005. A guide to medicinal plants in North Africa. Malaga, Spain: IUCN Center for Mediterranean Cooperation.
  • Grassilli E, Narloch R, Federzoni E, Ianzano L, Pisano F, Giovannoni R, Romano G, Masiero L, Leone BE, Bonin S, et al. 2013. Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy. Clin Cancer Res. 19:3820–3831.
  • Hoensch H, Groh B, Edler L, Kirch W. 2008. Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence. World J Gastroenterol. 14:2187–2193.
  • Igarashi K, Mikami T, Takahashiy, Sato H. 2008. Comparison of the preventive activity of isorhamnetin glycosides from atsumi-kabu (Red Turnip, Brassica, campestris L.) leaves on carbon tetrachloride-induced liver injury in mice. Biosci Biotechnol Biochem. 72:856–860.
  • Johnson JL, Rupasinghe SG, Stefani F, Schuler MA, Gonzalez de Mejia E. 2011. Citrus flavonoids luteolin, apigenin, and quercetin inhibit glycogen synthase kinase-3β enzymatic activity by lowering the interaction energy within the binding cavity. J Med Food. 14:325–333.
  • Kassem ME, Afifi MS, Marzouk MM, Mostafa MA. 2013. Two new flavonol glycosides and biological activities of Diplotaxis harra (Forssk.) Boiss. Nat Prod Res. 27:2272–2280.
  • Kwon KH, Murakami A, Tanaka T, Ohigashi H. 2005. Dietary rutin, but not its aglycone quercetin, ameliorates dextran sulfate sodium-induced experimental colitis in mice: attenuation of pro-inflammatory gene expression. Biochem Pharmacol. 69:395–406.
  • Li S, Guan J, Ge M, Huang P, Lin Y, Gan X. 2015. Intestinal mucosal injury induced by tryptase-activated protease-activated receptor 2 requires β-arrestin-2 in vitro. Mol Med Rep. 12:7181–7187.
  • Liu H, Mou Y, Zhao J, Wang J, Zhou L, Wang M, Wang D, Han J, Yu Z, Yang F. 2010. Flavonoids from Halostachys caspica and their antimicrobial and antioxidant activities. Molecules. 15:7933–7945.
  • Mai W, Kawakami K, Shakoori A, Kyo S, Miyashita K, Yokoi K, Jin M, Shimasaki T, Motoo Y, Minamoto T. 2009. Deregulated GSK3βsustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase. Clin Cancer Res. 15:6810–6819.
  • Mohammed MMD, El-Sharkawy ER, Matloub AA. 2013. Cytotoxic flavonoids from Diplotaxis harra (Forssk.) Boiss. growing in Sinai. J Med Plants Res. 7:19–23.
  • Nasri I, Bonnet D, Zwarycz B, D’Aldebert E, Khou S, Mezghani-Jarraya R, Quaranta M, Rolland C, Bonnart C, Mas E, et al. 2016 . PAR2-dependent activation of GSK3β regulates the survival of colon stem/progenitor cells. Am J Physiol Gastrointest Liver Physiol. 311:G221–G236.
  • Neuman MG, Nanau RM. 2012. Inflammatory bowel disease: role of diet, microbiota, life style. Transl Res. 160:29–44.
  • Noda S, Tanabe S, Suzuki T. 2013. Naringenin enhances intestinal barrier function through the expression and cytoskeletal association of tight junction proteins in Caco-2 cells. Mol Nutr Food Res. 57:2019–2028.
  • Pan MH, Lai CS, Wu JC, Ho CT. 2011. Molecular mechanisms for chemoprevention of colorectal cancer by natural dietary compounds. Mol Nutr Food Res. 55:32–45.
  • Ramadan MF, Amer MMA, Mansour HT, Wahdan KM, El-Sayed RM, El-Sanhoty S, El-Gleel WA. 2009. Bioactive lipids and antioxidant properties of wild Egyptian Pulicaria incise, Diplotaxis harra, and Avicennia marina. J Verbr Lebensm. 4:239–245.
  • Rossi M, Rosato V, Bosetti C, Lagiou P, Parpinel M, Bertuccio P, Negri E, Vecchia CL. 2010. Flavonoids, proanthocyanidins, and the risk of stomach cancer. Cancer Causes Control. 21:1597–1604.
  • Severson EA, Kwon M, Hilgarth RS, Parkos CA, Nusrat A. 2010. Glycogen Synthase Kinase 3 (GSK-3) influences epithelial barrier function by regulating occludin, claudin-1 and E-cadherin expression. Biochem Biophys Res Commun. 397:592–597.
  • Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, Kawakami K, Minamoto T. 2007. Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents. Cancer Sci. 98:1388–1393.
  • Steinbrecher KA, Wilson WIII, Cogswell PC, Baldwin AS. 2005. Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription. Mol Cell Biol. 25:8444–8455.
  • Triantafillidis JK, Nasioulas G, Kosmidis PA. 2009. Colorectal cancer and inflammatory bowel disease: epidemiology, risk factors, mechanisms of carcinogenesis and prevention strategies. Anticancer Res. 29:2727–2738.
  • Tsuchiya K, Nakamura T, Okamoto R, Kanai T, Watanabe M. 2007. Reciprocal targeting of Hath1 and beta-catenin by Wnt glycogen synthase kinase 3beta in human colon cancer. Gastroenterology. 132:208–220.
  • Vermeulen L, Snippert HJ. 2014. Stem cell dynamics in homeostasis and cancer of the intestine. Nat Rev Cancer. 14:468–480.
  • Vinothkumar R, Vinoth Kumar R, Sudha M, Viswanathan P, Balasubramanian T, Nalini N. 2014. Modulatory effect of troxerutin on biotransforming enzymes and preneoplasic lesions induced by 1,2-dimethylhydrazine in rat colon carcinogenesis. Exp Mol Pathol. 96:15–26.
  • Wang HL, Hart J, Fan L, Mustafi R, Bissonnette M. 2011. Upregulation of glycogen synthase kinase 3β in human colorectal adenocarcinomas correlates with accumulation of CTNNB1. Clin Colorectal Cancer. 10:30–36.
  • Wang Q, Zhou Y, Evers BM. 2006. Neurotensin phosphorylates GSK-3alpha/beta through the activation of PKC in human colon cancer cells. Neoplasia. 8:781–787.
  • Whittle BJ, Varga C, Posa A, Molnar A, Collin M, Thiemermann C. 2006. Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta. Br J Pharmacol. 147:575–582.