Effects of diclofenac on the pharmacokinetics of celastrol in rats and its transport

Reference

• Al-Amin MM, Uddin MM, Rahman MM, Reza HM, Rana MS. 2013. Effect of diclofenac and antidepressants on the inflammatory response in astrocyte cell culture. Inflammopharmacology. 21:421–425.
   PubMed Web of Science ®Google Scholar
• Astry B, Venkatesha SH, Laurence A, Christensen-Quick A, Garzino-Demo A, Frieman MB, O'Shea JJ, Moudgil KD. 2015. Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ. Clin Immunol. 157:228–238.
   PubMed Web of Science ®Google Scholar
• Binkhathlan Z, Lavasanifar A. 2013. P-glycoprotein inhibition as a therapeutic approach for overcoming multidrug resistance in cancer: current status and future perspectives. Curr Cancer Drug Targets. 13:326–346.
   PubMed Web of Science ®Google Scholar
• Chai Z, Zhou WJ, Gao L, Wang YH, Fan HJ, Zhou R. 2011. Experimental progress of liver toxicity of Tripterygium wilfordii and its mechanism. Chinese J Experi Trad Med Formula. 17:243–246.
   Google Scholar
• Chew CC, Ng S, Chee YL, Koo TW, Liew MH, Chee EL, Modamio P, Fernandez C, Marino EL, Segarra I. 2017. Diclofenac sex-divergent drug-drug interaction with sunitinib: pharmacokinetics and tissue distribution in male and female mice. Invest New Drugs. 35:399–411.
   PubMed Web of Science ®Google Scholar
• Dai Y, Desano J, Tang W, Meng X, Meng Y, Burstein E, Lawrence TS, Xu L. 2010. Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB. PLoS One. 5:e14153.
   PubMed Web of Science ®Google Scholar
• FDA. 2013. Guidance for industry, bioanalytical method validation. Rockville (MD): FDA.
   Google Scholar
• Gan TJ. 2010. Diclofenac: an update on its mechanism of action and safety profile. Curr Med Res Opin. 26:1715–1731.
   PubMed Web of Science ®Google Scholar
• Guyot P, Pandhi S, Nixon RM, Iqbal A, Chaves RL, Andrew Moore R. 2017. Efficacy and safety of diclofenac in osteoarthritis: results of a network meta-analysis of unpublished legacy studies. Scand J Pain. 16:74–88.
   PubMed Web of Science ®Google Scholar
• Ji N, Li J, Wei Z, Kong F, Jin H, Chen X, Li Y, Deng Y. 2015. Effect of celastrol on growth inhibition of prostate cancer cells through the regulation of hERG channel in vitro. Biomed Res Int. 2015:308475.
   PubMed Web of Science ®Google Scholar
• Kataoka M, Yokoyama T, Masaoka Y, Sakuma S, Yamashita S. 2011. Estimation of p-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. Eur J Pharm Sci. 44:544–551.
   PubMed Web of Science ®Google Scholar
• Lagas JS, van der Kruijssen CM, van de Wetering K, Beijnen JH, Schinkel AH. 2009. Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transport by diclofenac and benzbromarone. Drug Metab Dispos. 37:129–136.
   PubMed Web of Science ®Google Scholar
• Li H, Li J, Liu L, Zhang Y, Luo Y, Zhang X, Yang P, Zhang M, Yu W, Qu S. 2016. Elucidation of the intestinal absorption mechanism of celastrol using the Caco-2 cell transwell model. Planta Med. 82:1202–1207.
   PubMed Web of Science ®Google Scholar
• Li H, Liu L, Xie L, Gan D, Jiang X. 2016. Effects of berberine on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism. Pharm Biol. 54:2886–2894.
   PubMed Web of Science ®Google Scholar
• Li PP, He W, Yuan PF, Song SS, Lu JT, Wei W. 2015. Celastrol induces mitochondria-mediated apoptosis in hepatocellular carcinoma bel-7402 cells. Am J Chin Med. 43:137–148.
   PubMed Web of Science ®Google Scholar
• Niwa T, Imagawa Y, Yamazaki H. 2014. Drug interactions between nine antifungal agents and drugs metabolized by human cytochromes P450. Curr Drug Metab. 15:651–679.
   PubMed Web of Science ®Google Scholar
• Orido T, Fujino H, Hasegawa Y, Toyomura K, Kawashima T, Murayama T. 2008. Indomethacin decreases arachidonic acid uptake in HCA-7 human colon cancer cells. J Pharmacol Sci. 108:389–392.
   PubMed Web of Science ®Google Scholar
• Pinna GF, Fiorucci M, Reimund JM, Taquet N, Arondel Y, Muller CD. 2004. Celastrol inhibits pro-inflammatory cytokine secretion in Crohn's disease biopsies. Biochem Biophys Res Commun. 322:778–786.
   PubMed Web of Science ®Google Scholar
• Rowcliffe M, Nezami B, Westphal ES, Rainka M, Janda M, Bates V, Gengo F. 2016. Topical diclofenac does not affect the antiplatelet properties of aspirin as compared to the intermediate effects of oral diclofenac: a prospective, randomized, complete crossover study. J Clin Pharmacol. 56:422–428.
   PubMed Web of Science ®Google Scholar
• Sanchez-Covarrubias L, Slosky LM, Thompson BJ, Zhang Y, Laracuente ML, DeMarco KM, Ronaldson PT, Davis TP. 2014. P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac. PLoS One. 9:e88516.
   PubMed Web of Science ®Google Scholar
• Sharma S, Mishra R, Walker BL, Deshmukh S, Zampino M, Patel J, Anamalai M, Simpson D, Singh IS, Kaushal S, et al. 2015. Celastrol, an oral heat shock activator, ameliorates multiple animal disease models of cell death. Cell Stress Chaperones. 20:185–201.
   PubMed Web of Science ®Google Scholar
• Shrivastava S, Jeengar MK, Reddy VS, Reddy GB, Naidu VG. 2015. Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways. Exp Mol Pathol. 98:313–327.
   PubMed Web of Science ®Google Scholar
• Takara K, Hayashi R, Kokufu M, Yamamoto K, Kitada N, Ohnishi N, Yokoyama T. 2009. Effects of nonsteroidal anti-inflammatory drugs on the expression and function of P-glycoprotein/MDR1 in Caco-2 cells. Drug Chem Toxicol. 32:332–337.
   PubMed Web of Science ®Google Scholar
• Wang J, Jiang Z, Ji J, Wang X, Wang T, Zhang Y, Tai T, Chen M, Sun L, Li X, et al. 2013. Gene expression profiling and pathway analysis of hepatotoxicity induced by triptolide in Wistar rats. Food Chem Toxicol. 58:495–505.
   PubMed Web of Science ®Google Scholar
• Wang K, Zhao J, Lang J. 2016. The effects of verapamil on the pharmacokinetics of curculigoside in rats. Pharm Biol. 54:3001–3008.
   PubMed Web of Science ®Google Scholar
• Wang S, Liu K, Wang X, He Q, Chen X. 2011. Toxic effects of celastrol on embryonic development of zebrafish (Danio rerio). Drug Chem Toxicol. 34:61–65.
   PubMed Web of Science ®Google Scholar
• Wang X, Zhang X, Huang X, Li Y, Wu M, Liu J. 2015. The drug-drug interaction of sorafenib mediated by P-glycoprotein and CYP3A4. Xenobiotica. 46:651–658.
   PubMed Web of Science ®Google Scholar
• Yan G, Zhang H, Wang W, Li Y, Mao C, Fang M, Yi X, Zhang J. 2017. Investigation of the influence of glycyrrhizin on the pharmacokinetics of celastrol in rats using LC-MS and its potential mechanism. Xenobiotica. 47:607–613.
   PubMed Web of Science ®Google Scholar
• Yang F, Ren L, Zhuo L, Ananda S, Liu L. 2012. Involvement of oxidative stress in the mechanism of triptolide-induced acute nephrotoxicity in rats. Exp Toxicol Pathol. 64:905–911.
   PubMed Web of Science ®Google Scholar
• Yang H, Chen D, Cui QC, Yuan X, Dou QP. 2006. Celastrol, a triterpene extracted from the Chinese “Thunder of God Vine,” is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. Cancer Res. 66:4758–4765.
   PubMed Web of Science ®Google Scholar
• Yu CP, Sweet DH, Peng YH, Hsieh YW, Chao PL, Hou YC, Lin SP. 2017. Effects of nonsteroidal anti-inflammatory drugs on the renal excretion of indoxyl sulfate, a nephro-cardiovascular toxin, in rats. Eur J Pharm Sci. 101:66–70.
   PubMed Web of Science ®Google Scholar
• Yu Y, Koehn CD, Yue Y, Li S, Thiele GM, Hearth-Holmes MP, Mikuls TR, O'Dell JR, Klassen LW, Zhang Z, et al. 2015. Celastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formation. Curr Mol Med. 15:401–410.
   PubMed Web of Science ®Google Scholar