References
- Ben-Hur T, Idelson M, Khaner H, Pera M, Reinhartz E, Itzik A, Reubinoff BE. 2004. Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats. Stem Cells. 22:1246–1255.
- Farshid AA, Tamaddonfard E. 2015. Histopathological and behavioral evaluations of the effects of crocin, Safranal and insulin on diabetic peripheral neuropathy in rats. Avicenna J Phytomed. 5:469–478.
- Farzanehfar P. 2016. Towards a better treatment option for Parkinson’s disease: a review of adult neurogenesis. Neurochem Res. 41:3161–3170.
- Guloglu MO, Larsen A. 2016. Dopaminergic differentiation of human embryonic stem cells on PA6-derived adipocytes. Methods Mol Biol. 1341:235–244.
- Guloglu MO, Larsen A, Brundin P. 2014. Adipocytes derived from PA6 cells reliably promote the differentiation of dopaminergic neurons from human embryonic stem cells. J Neurosci Res. 92:564–573.
- Hu Z, Pu J, Jiang H, Zhong P, Qiu J, Li F, Wang X, Zhang B, Yan Z, Feng J. 2015. Generation of naivetropic induced pluripotent stem cells from Parkinson’s disease patients for high-efficiency genetic manipulation and disease modeling. Stem Cells Dev. 24:2591–2604.
- Khazdair MR, Boskabady MH, Hosseini M, Rezaee R, M Tsatsakis A. 2015. The effects of Crocus sativus (saffron) and its constituents on nervous system: a review. Avicenna J Phytomed. 5:376–391.
- Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z, Carrillo-Reid L, Auyeung G, Antonacci C, Buch A, et al. 2011. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease. Nature. 480:547–551.
- Love RM, Branton RL, Karlsson J, Brundin P, Clarke DJ. 2002. Effects of antioxidant pretreatment on the survival of embryonic dopaminergic neurons in vitro and following grafting in an animal model of Parkinson’s disease. Cell Transplant. 11:653–662.
- Nakamura T, Cho DH, Lipton SA. 2012. Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases. Exp Neurol. 238:12–21.
- Shafiee M, Arekhi S, Omranzadeh A, Sahebkar A. 2018. Saffron in the treatment of depression, anxiety and other mental disorders: current evidence and potential mechanisms of action. J Affect Disord. 227:330–337.
- Song T, Chen G, Wang Y, Mao G, Wang Y, Bai H. 2008. Chemically defined sequential culture media for TH + cell derivation from human embryonic stem cells. Mol Hum Reprod. 14:619–625.
- Tamaddonfard E, Farshid AA, Maroufi S, Kazemi-Shojaei S, Erfanparast A, Asri-Rezaei S, Taati M, Dabbaghi M, Escort M. 2014. Effects of SAFranal, a constituent of SAFfron, and vitamin E on nerve functions and histopathology following crush injury of sciatic nerve in rats. Phytomed Int J Phytother Phytopharm. 21:717–723.
- Toriumi H, Yoshikawa M, Matsuda R, Nishimura F, Yamada S, Hirabayashi H, Nakase H, Nonaka J, Ouji Y, Ishizaka S, et al. 2009. Treatment of Parkinson’s disease model mice with allogeneic embryonic stem cells: necessity of immunosuppressive treatment for sustained improvement. Neurol Res. 31:220–227.
- Velusamy T, Panneerselvam AS, Purushottam M, Anusuyadevi M, Pal PK, Jain S, Essa MM, Guillemin GJ, Kandasamy M. 2017. Protective effect of antioxidants on neuronal dysfunction and plasticity in Huntington’s disease. Oxidat Med Cell Longev. 2017:3279061.
- Wang L, Wu G, Qin X, Ma Q, Zhou Y, Liu S, Tan Y. 2015. Expression of nodal on bronchial epithelial cells influenced by lung microbes through DNA methylation modulates the differentiation of T-helper cells. Cell Physiol Biochem. 37:2012–2022.
- Zhu KJ, Yang JS. 2014. Anti-allodynia effect of Safranal on neuropathic pain induced by spinal nerve transection in rat. Int J Clin Exp Med. 7:4990–4996.