1,251
Views
18
CrossRef citations to date
0
Altmetric
Research Article

In vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism

, , , , , & show all
Pages 626-631 | Received 27 Jun 2018, Accepted 14 Sep 2018, Published online: 17 Dec 2018

References

  • Akila P, Vennila L. 2016. Chlorogenic acid a dietary polyphenol attenuates isoproterenol induced myocardial oxidative stress in rat myocardium: an in vivo study. Biomed Pharmacother. 84:208–214.
  • Ali N, Rashid S, Nafees S, Hasan SK, Shahid A, Majed F, Sultana S. 2017. Protective effect of chlorogenic acid against methotrexate induced oxidative stress, inflammation and apoptosis in rat liver: an experimental approach. Chem Biol Interact. 272:80–91.
  • Bao L, Li J, Zha D, Zhang L, Gao P, Yao T, Wu X. 2018. Chlorogenic acid prevents diabetic nephropathy by inhibiting oxidative stress and inflammation through modulation of the Nrf2/HO-1 and NF-ĸB pathways. Int. Immunopharmacol. 54:245–253.
  • Fan D, Guo Q, Shen J, Zheng K, Lu C, Zhang G, Lu A, He X. 2018. The effect of triptolide in rheumatoid arthritis: from basic research towards clinical translation. Int J Mol Sci. 19:376.
  • Feng Y, Yu YH, Wang ST, Ren J, Camer D, Hua YZ, Zhang Q, Huang J, Xue DL, Zhang XF, et al. 2016. Chlorogenic acid protects d-galactose-induced liver and kidney injury via antioxidation and anti-inflammation effects in mice. Pharm Biol. 54:1027–1034.
  • Guo H, Pan C, Chang B, Wu X, Guo J, Zhou Y, Liu H, Zhu Z, Chang B, Chen L. 2016. Triptolide improves diabetic nephropathy by regulating Th cell balance and macrophage infiltration in rat models of diabetic nephropathy. Exper Clin Endocrinol Diabetes. 124:389–398.
  • Högberg J, Larson RE, Kristoferson A, Orrenius S. 1974. NADPH-dependent reductase solubilized from microsomes by peroxidation and its activity. Biochem Biophys Res Commun. 56:836–842.
  • Hu H, Huang G, Wang H, Li X, Wang X, Feng Y, Tan B, Chen T. 2018. Inhibition effect of triptolide on human epithelial ovarian cancer via adjusting cellular immunity and angiogenesis. Oncol Rep. 39:1191–1196.
  • Li J, Shen F, Guan C, Wang W, Sun X, Fu X, Huang M, Jin J, Huang Z. 2014. Activation of Nrf2 protects against triptolide-induced hepatotoxicity. PLoS One. 9:e100685.
  • Mei X, Zhou L, Zhang T, Lu B, Sheng Y, Ji L. 2018. Chlorogenic acid attenuates diabetic retinopathy by reducing VEGF expression and inhibiting VEGF-mediated retinal neoangiogenesis. Vascular Pharmacol. 101:29–37.
  • Naveed M, Hejazi V, Abbas M, Kamboh AA, Khan GJ, Shumzaid M, Ahmad F, Babazadeh D, FangFang X, Modarresi-Ghazani F, et al. 2018. Chlorogenic acid (CGA): a pharmacological review and call for further research. Biomed Pharmacother. 97:67–74.
  • Pang C, Sheng YC, Jiang P, Wei H, Ji LL. 2015. Chlorogenic acid prevents acetaminophen-induced liver injury: the involvement of CYP450 metabolic enzymes and some antioxidant signals. J Zhejiang Uni Sci B. 16:602–610.
  • Roh T, De U, Lim SK, Kim MK, Choi SM, Lim DS, Yoon S, Kacew S, Kim HS, Lee BM. 2018. Detoxifying effect of pyridoxine on acetaminophen-induced hepatotoxicity via suppressing oxidative stress injury. Food Chem Toxicol. 114:11–22.
  • Shi H, Shi A, Dong L, Lu X, Wang Y, Zhao J, Dai F, Guo X. 2016. Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress. Clin Nutr. 35:1366–1373.
  • Tao Y, Zhang ML, Ma PC, Sun JF, Zhou WQ, Cao YP, Li LJ. 2012. Triptolide inhibits proliferation and induces apoptosis of human melanoma A375 cells. Asian Pacific J Cancer Prev. 13:1611–1615.
  • Wei C, Zhou L, Zhang Y, Zhang J, Zhang Q, Tao K. 2017. Protective effect of quercetin against immunological liver injury through activating Nrf2/ARE signaling pathway. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 33:300–304.
  • Wei M, Zheng Z, Shi L, Jin Y, Ji L. 2018. Natural polyphenol chlorogenic acid protects against acetaminophen-induced hepatotoxicity by activating ERK/Nrf2 antioxidative pathway. Toxicol Sci. 162:99–112.
  • Xi C, Peng S, Wu Z, Zhou Q, Zhou J. 2017. Toxicity of triptolide and the molecular mechanisms involved. Biomed Pharmacother. 90:531–541.
  • Xiong J, Su T, Qu Z, Yang Q, Wang Y, Li J, Zhou S. 2016. Triptolide has anticancer and chemosensitization effects by down-regulating Akt activation through the MDM2/REST pathway in human breast cancer. Oncotarget. 7:23933–23946.
  • Xu D, Hu L, Xia X, Song J, Li L, Song E, Song Y. 2014. Tetrachlorobenzoquinone induces acute liver injury, up-regulates HO-1 and NQO1 expression in mice model: the protective role of chlorogenic acid. Environ Toxicol Pharmacol. 37:1212–1220.
  • Xu Y, Chen J, Yu X, Tao W, Jiang F, Yin Z, Liu C. 2010. Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice. Inflamm Res. 59:871–877.
  • Zhang C, He XJ, Li L, Lu C, Lu AP. 2017. Effect of the natural product triptolide on pancreatic cancer: a systematic review of preclinical studies. Frontiers Pharmacol. 8:490
  • Ziaei S, Halaby R. 2016. Immunosuppressive, anti-inflammatory and anti-cancer properties of triptolide: A mini review. Avicenna J Phytomed. 6:149–164.