3,992
Views
29
CrossRef citations to date
0
Altmetric
Research Article

Pueraria lobata root polysaccharide alleviates glucose and lipid metabolic dysfunction in diabetic db/db mice

, , , , &
Pages 380-388 | Received 18 Nov 2020, Accepted 28 Feb 2021, Published online: 01 Apr 2021

References

  • Abdin AA, Baalash AA, Hamooda HE. 2010. Effects of rosiglitazone and aspirin on experimental model of induced type 2 diabetes in rats: focus on insulin resistance and inflammatory markers. J Diabetes Complications. 24(3):168–178.
  • Batista LO, Ramos VW, Rosas Fernández MA, Concha Vilca CM, Albuquerque KT. 2019. Oral solution of fructose promotes SREBP-1c high-expression in the hypothalamus of Wistar rats. Nutr Neurosci. 22(9):648–654.
  • Belke DD, Severson DL. 2012. Diabetes in mice with monogenic obesity: the db/db mouse and its use in the study of cardiac consequences. Methods Mol Biol. 933:47–57.
  • Ceriello A. 2005. Postprandial hyperglycemia and diabetes complications: is it time to treat? Diabetes. 54(1):1–7.
  • Chadt A, Al-Hasani H. 2020. Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease. Pflugers Arch. 472(9):1273–1298.
  • Chen C, Huang Q, Li C, Fu X. 2017. Hypoglycemic effects of a Fructus Mori polysaccharide in vitro and in vivo. Food Funct. 8(7):2523–2535.
  • Chen C, You LJ, Huang Q, Fu X, Zhang B, Liu RH, Li C. 2018. Modulation of gut microbiota by mulberry fruit polysaccharide treatment of obese diabetic db/db mice. Food Funct. 9(7):3732–3742.
  • Dong Z, Zhang M, Li H, Zhan Q, Lai F, Wu H. 2020. Structural characterization and immunomodulatory activity of a novel polysaccharide from Pueraria lobata (Willd.) Ohwi root. Int J Biol Macromol. 154:1556–1564.
  • Duckworth WC. 2001. Hyperglycemia and cardiovascular disease. Curr Atheroscler Rep. 3(5):383–391.
  • Filippatos TD, Panagiotopoulou TV, Elisaf MS. 2014. Adverse effects of GLP-1 receptor agonists. Rev Diabet Stud. 11(3–4):202–230.
  • Han P, Cui Q, Lu W, Yang S, Shi M, Li Z, Gao P, Xu B, Li Z. 2019. Hepatocyte growth factor plays a dual role in tendon-derived stem cell proliferation, migration, and differentiation. J Cell Physiol. 234(10):17382–17391.
  • Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS. 2002. A central role for JNK in obesity and insulin resistance. Nature. 420(6913):333–336.
  • Hsiang JC, Gane EJ, Bai WW, Gerred SJ. 2015. Type 2 diabetes: a risk factor for liver mortality and complications in hepatitis B cirrhosis patients. J Gastroenterol Hepatol. 30(3):591–599.
  • Hu X, Wang S, Xu J, Wang DB, Chen Y, Yang GZ. 2014. Triterpenoid saponins from Stauntonia chinensis ameliorate insulin resistance via the AMP-activated protein kinase and IR/IRS-1/PI3K/Akt pathways in insulin-resistant HepG2 cells. Int J Mol Sci. 15(6):10446–10458.
  • Hung HY, Qian K, Morris-Natschke SL, Hsu CS, Lee KH. 2012. Recent discovery of plant-derived anti-diabetic natural products. Nat Prod Rep. 29(5):580–606.
  • Jiang S, Du P, An L, Yuan G, Sun Z. 2013. Anti-diabetic effect of Coptis chinensis polysaccharide in high-fat diet with STZ-induced diabetic mice. Int J Biol Macromol. 55:118–122.
  • Ju J, Song JL, Park KY. 2015. Antiobesity effects of bamboo salt in C57BL/6 mice. J Med Food. 18(6):706–710.
  • Khalilpourfarshbafi M, Devi Murugan D, Abdul Sattar MZ, Sucedaram Y, Abdullah NA. 2019. Withaferin A inhibits adipogenesis in 3T3-F442A cell line, improves insulin sensitivity and promotes weight loss in high fat diet-induced obese mice. PloS One. 14(6):e0218792.
  • Patle D, Vyas M, Khatik GL. 2020. A review on natural products and herbs used in the management of diabetes. Curr Diabetes Rev. 7(2):186–197.
  • Petroglou D, Kanellos I, Savopoulos C, Kaiafa G, Chrysochoou A, Skantzis P, Daios S, Hatzitolios AI, Giannoglou G. 2020. The LDL-receptor and its molecular properties: from theory to novel biochemical and pharmacological approaches in reducing LDL-cholesterol. Curr Med Chem. 27(2):317–333.
  • Reidy K, Kang HM, Hostetter T, Susztak K. 2014. Molecular mechanisms of diabetic kidney disease. J Clin Invest. 124(6):2333–2340.
  • Ros S, Zafra D, Valles-Ortega J, García-Rocha M, Forrow S, Domínguez J, Calbó J, Guinovart JJ. 2010. Hepatic overexpression of a constitutively active form of liver glycogen synthase improves glucose homeostasis. J Biol Chem. 285(48):37170–37177.
  • She S, Liu W, Li T, Hong Y. 2014. Effects of puerarin in STZ-induced diabetic rats by oxidative stress and the TGF-beta1/Smad2 pathway. Food Funct. 5(5):944–950.
  • Song Z, Guo Y, Zhou M, Zhang X. 2014. The PI3K/p-Akt signaling pathway participates in calcitriol ameliorating podocyte injury in DN rats. Metabolism. 63(10):1324–1333.
  • Valenti L, Rametta R, Dongiovanni P, Maggioni M, Fracanzani AL, Zappa M, Lattuada E, Roviaro G, Fargion S. 2008. Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis. Diabetes. 57(5):1355–1362.
  • Wang L, Li C, Huang Q, Fu X. 2020. Polysaccharide from Rosa roxburghii Tratt fruit attenuates hyperglycemia and hyperlipidemia and regulates colon microbiota in diabetic db/db mice. J Agric Food Chem. 68(1):147–159.
  • Wang LY, Wang Y, Xu DS, Ruan KF, Feng Y, Wang S. 2012. MDG-1, a polysaccharide from Ophiopogon japonicus exerts hypoglycemic effects through the PI3K/Akt pathway in a diabetic KKAy mouse model. J Ethnopharmacol. 143(1):347–354.
  • Wong KH, Li GQ, Li KM, Razmovski-Naumovski V, Chan K. 2011. Kudzu root: traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases. J Ethnopharmacol. 134(3):584–607.
  • Xia JY, Morley TS, Scherer PE. 2014. The adipokine/ceramide axis: key aspects of insulin sensitization. Biochimie. 96:130–139.
  • Yan F, Zhang J, Zhang L, Zheng X. 2016. Mulberry anthocyanin extract regulates glucose metabolism by promotion of glycogen synthesis and reduction of gluconeogenesis in human HepG2 cells. Food Funct. 7(1):425–433.
  • Zandbergen F, Plutzky J. 2007. PPARalpha in atherosclerosis and inflammation. Biochim Biophys Acta. 1771(8):972–982.
  • Zhang Y, Wang H, Yu L, Chen J. 2015. The Puerarin improves renal function in STZ-induced diabetic rats by attenuating eNOS expression. Ren Fail. 37(4):699–703.
  • Zhang Z, Wang J, Wang H. 2018. Correlation of blood glucose, serum chemerin and insulin resistance with NAFLD in patients with type 2 diabetes mellitus. Exp Ther Med. 15:2936–2940.
  • Zhu Y, Pereira RO, O'Neill BT, Riehle C, Ilkun O, Wende AR, Rawlings TA, Zhang YC, Zhang Q, Klip A, et al. 2013. Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation. Mol Endocrinol. 27(1):172–184.