Prevention of seminal vesicle damage by Mucuna pruriens var. pruriens seed extract in chronic unpredictable mild stress mice

References

• Ahmad MK, Mahdi AA, Shukla KK, Islam N, Jaiswar SP, Ahmad S. 2008. Effect of Mucuna pruriens on semen profile and biochemical parameters in seminal plasma of infertile men. Fertil Steril. 90(3):627–635.
   PubMed Web of Science ®Google Scholar
• Aniagu SO, Nwinyi FC, Akumka DD, Ditse M, Nwaneri PCE, Wambebe C, Gamaniel K. 2005. Toxicity studies in rats fed nature cure bitters. Afr J Biotechnol. 4:72–78.
   Google Scholar
• Antoniuk S, Bijata M, Ponimaskin E, Wlodarczyk J. 2019. Chronic unpredictable mild stress for modeling depression in rodents: meta-analysis of model reliability. Neurosci Biobehav Rev. 99:101–116.
   PubMed Web of Science ®Google Scholar
• Arun S, Burawat J, Sukhorum W, Sampannang A, Maneenin C, Iamsaard S. 2016. Chronic restraint stress induces sperm acrosome reaction and changes in testicular tyrosine phosphorylated proteins in rats. Int J Reprod Biomed. 14(7):443–452.
   PubMedGoogle Scholar
• Arun S, Chaiyamoon A, Lapyuneyong N, Bunsueb S, Wu AT, Iamsaard S. 2021. Chronic stress affects tyrosine phosphorylated protein expression and secretion of male rat epididymis. Andrologia. 53(3):e13981.
   PubMed Web of Science ®Google Scholar
• Awodele O, Kale OE, Odewabi AO, Ekor M, Salau BA, Adefule-Ositelu AO. 2017. Safety evaluation of Bon-santé cleanser® polyherbal in male Wistar rats: further investigations on androgenic and toxicological profile. J Tradit Complement Med. 8(1):212–219.
   PubMedGoogle Scholar
• Ayuraved Wittayarai Foundation 1998. Thai traditional medicine textbook (Paet-Saat-Song-Kror). Bangkok: Ministry of Public Health.
   Google Scholar
• Beeder LA, Samplaski MK. 2020. Effect of antidepressant medications on semen parameters and male fertility. Int J Urol. 27(1):39–46.
   PubMed Web of Science ®Google Scholar
• Beere HM, Wolf BB, Cain K, Mosser DD, Mahboubi A, Kuwana T, Tailor P, Morimoto RI, Cohen GM, Green DR. 2000. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat Cell Biol. 2(8):469–475.
   PubMed Web of Science ®Google Scholar
• Bergmann N, Gyntelberg F, Faber J. 2014. The appraisal of chronic stress and the development of the metabolic syndrome: a systematic review of prospective cohort studies. Endocr Connect. 3:55–80.
   PubMed Web of Science ®Google Scholar
• Bhongade MB, Prasad S, Jiloha RC, Ray PC, Mohapatra S, Koner BC. 2015. Effect of psychological stress on fertility hormones and seminal quality in male partners of infertile couples. Andrologia. 47(3):336–342.
   PubMed Web of Science ®Google Scholar
• Byun JS, Lyu SW, Seok HH, Kim WJ, Shim SH, Bak CW. 2013. Sexual dysfunctions induced by stress of timed intercourse and medical treatment. BJU Int. 11:227–234.
   Google Scholar
• Cacciatore I, Marinelli L, Di Stefano A, Di Marco V, Orlando G, Gabriele M, Gatta DMP, Ferrone A, Franceschelli S, Speranza L, et al. 2018. Chelating and antioxidant properties of l-dopa containing tetrapeptide for the treatment of neurodegenerative diseases. Neuropeptides. 71:11–20.
   PubMed Web of Science ®Google Scholar
• Candenas L, Chianese R. 2020. Exosome composition and seminal plasma proteome: a promising source of biomarkers of male infertility. Int J Mol Sci. 21:1–27.
   Web of Science ®Google Scholar
• Cartwright C, Gibson K, Read J, Cowan O, Dehar T. 2016. Long-term antidepressant use: patient perspectives of benefits and adverse effects. Patient Prefer Adherence. 10:1401–1407.
   PubMed Web of Science ®Google Scholar
• Chaichun A, Arun S, Burawat J, Kanla P, Iamsaard S. 2017. Localization and identification of tyrosine phosphorylated proteins in adult Sprague-Dawley rat testis. Int J Morphol. 35(4):1322–1327.
   Web of Science ®Google Scholar
• Choowong-In P, Sattayasai J, Boonchoong P, Poodendaen C, Wu A, Tangsrisakda N, Sawatpanich T, Arun S, Uabundit N, Iamsaard S. 2021a. Protective effects of Thai Mucuna pruriens (L.) DC. var. pruriens seeds on sexual behaviors and essential reproductive markers in chronic unpredictable mild stress mice. J Tradit Complement Med. 12(4):402–413.
   PubMedGoogle Scholar
• Choowong-In P, Sattayasai J, Poodendaen C, Iamsaard S. 2021b. Decreased expression of AKAP4 and TyrPho proteins in testis, epididymis, and spermatozoa with low sexual performance of mice induced by modified CUMS. Andrologia. 53(3):e13977.
   PubMed Web of Science ®Google Scholar
• Divya BJ, Suman B, Venkataswamy M, ThyagaRaju K. 2017. The traditional uses and pharmacological activities of Mucuna pruriens (L) DC: a comprehensive review. Indo Am J Pharm Res. 7:7516–7525.
   Google Scholar
• Dogani M, Askari N, Kalantari-Hesari A, Rahbar FH. 2022. The effects of P. atlantica as a libido booster and sexual enhancer on the reproductive system of male rats. J Tradit Complement Med. 12(4):345–353.
   PubMedGoogle Scholar
• Dong B, Shi Z, Dong Y, Chen J, Wu ZX, Wu W, Chen ZS, Han C. 2022. Quercetin ameliorates oxidative stress‑induced cell apoptosis of seminal vesicles via activating Nrf2 in type 1 diabetic rats. Biomed Pharmacother. 151:1–6.
   Web of Science ®Google Scholar
• Drabovich AP, Saraon P, Jarvi K, Diamandis EP. 2014. Seminal plasma as a diagnostic fluid for male reproductive system disorders. Nat Rev Urol. 11(5):278–288.
   PubMed Web of Science ®Google Scholar
• Elizabeth A, Adegbuyi A, Olusegun A, Benneth BA, Anthony E, Abayomi A, Solomon U. 2020. Morin hydrate attenuates chronic stress-induced memory impairment and degeneration of hippocampal subfields in mice: the role of oxidative, nitrergic and neuroinflammatory pathways. Metab Brain Dis. 35(7):1145–1156.
   PubMed Web of Science ®Google Scholar
• Fahim AT, Abd El-Fattah AA, Sadik N, Ali BM. 2019. Resveratrol and dimethyl fumarate ameliorate testicular dysfunction caused by chronic unpredictable mild stress-induced depression in rats. Arch Biochem Biophys. 665:152–165.
   PubMed Web of Science ®Google Scholar
• Iamsaard S, Arun S, Burawat J, Yannasithinon S, Tongpan S, Bunsueb S, Lapyuneyong N, Choowong-In P, Tangsrisakda N, Chaimontri C, et al. 2020. Evaluation of antioxidant capacity and reproductive toxicity of aqueous extract of Thai Mucuna pruriens seeds. J Integr Med. 18(3):265–273.
   PubMedGoogle Scholar
• Iamsaard S, Tongpan S, Yannasithinon S, Arun S, Wu ATH, Sukhorum W. 2021. Effect of chronic stress on expression and secretion of seminal vesicle proteins in adult rats. Andrologia. 53(1):e13800.
   PubMed Web of Science ®Google Scholar
• Ickowicz D, Finkelstein M, Breitbart H. 2012. Mechanism of sperm capacitation and the acrosome reaction: role of protein kinases. Asian J Androl. 14(6):816–821.
   PubMed Web of Science ®Google Scholar
• Ilacqua A, Izzo G, Emerenziani GP, Baldari C, Aversa A. 2018. Lifestyle and fertility: the influence of stress and quality of life on male fertility. Reprod Biol Endocrinol. 16(1):1–11.
   PubMedGoogle Scholar
• Jodko PK, Sikora B, Kluzek M, Przybylski P, Litwinienko G. 2022. Antiradical activity of dopamine, L-DOPA, adrenaline, and noradrenaline in water/methanol and in liposomal systems. J Org Chem. 87(3):1791–1804.
   PubMed Web of Science ®Google Scholar
• Juyena NS, Stelletta C. 2012. Seminal plasma: an essential attribute to spermatozoa. J Androl. 33(4):536–551.
   PubMedGoogle Scholar
• Kolbasi B, Bulbul MV, Karabulut S, Altun CE, Cakici C, Ulfer G, Mudok T, Keskin I. 2021. Chronic unpredictable stress disturbs the blood-testis barrier affecting sperm parameters in mice. Reprod Biomed Online. 42(5):983–995.
   PubMed Web of Science ®Google Scholar
• Lampariello LR, Cortelazzo A, Guerranti R, Sticozzi C, Valacchi G. 2012. The magic velvet bean of Mucuna pruriens. J Tradit Complement Med. 2(4):331–339.
   PubMedGoogle Scholar
• Lapyuneyong N, Tangsrisakda N, Choowong-In P, Chaisiwamongkol K, Uabundit N, Sawatpanich T, Arun S, Wu AT, Iamsaard S. 2022. Seed extract of Thai Mucuna pruriens reduced male reproductive damage in rats induced by chronic stress. Pharm Biol. 60(1):374–383.
   PubMed Web of Science ®Google Scholar
• Lin M, Lee YH, Xu W, Baker MA, Aitken RJ. 2006. Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse. Biol Reprod. 75(4):588–597.
   PubMed Web of Science ®Google Scholar
• Loboda A, Damulewicz M, Pyza E, Jozkowicz A, Dulak J. 2016. Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism. Cell Mol Life Sci. 73(17):3221–3247.
   PubMed Web of Science ®Google Scholar
• Longhi JG, Perez E, Lima JJ, Cândido LMB. 2011. In vitro evaluation of Mucuna pruriens (L.) DC. antioxidant activity. Braz J Pharm Sci. 47(3):535–544.
   Web of Science ®Google Scholar
• Mahajan GK, Mahajan AY, Mahajan RT. 2012. Efficacy of aphrodisiac plants towards improvement in semen quality and motility in infertile males. J Complement Integr Med. 9(1):1–12.
   PubMedGoogle Scholar
• Marin MF, Lord C, Andrews J, Juster RP, Sindi S, Arsenault LG, Fiocco AJ, Lupien SJ. 2011. Chronic stress, cognitive functioning and mental health. Neurobiol Learn Mem. 96(4):583–595.
   PubMed Web of Science ®Google Scholar
• Misra L, Wagner H. 2007. Extraction of bioactive principles from Mucuna pruriens seeds. Indian J Biochem Biophys. 44(1):56–60.
   PubMed Web of Science ®Google Scholar
• Naz RK, Rajesh PB. 2004. Role of tyrosine phosphorylation in sperm capacitation/acrosome reaction. Reprod Biol Endocrinol. 2(1):75–12.
   PubMedGoogle Scholar
• Nimrouzi M, Jaladat AM, Zarshenas MM. 2020. A panoramic view of medicinal plants traditionally applied for impotence and erectile dysfunction in Persian medicine. J Tradit Complement Med. 10(1):7–12.
   PubMedGoogle Scholar
• Oladapo OM, Ben-Azu B, Ajayi AM, Emokpae O, Eneni AO, Omogbiya IA, Iwalewa EO. 2021. Naringin confers protection against psychosocial defeat stress-induced neurobehavioral deficits in mice: involvement of glutamic acid decarboxylase isoform-67, oxido-nitrergic stress, and neuroinflammatory mechanisms. J Mol Neurosci. 71(3):431–445.
   PubMed Web of Science ®Google Scholar
• Pathania R, Chawla P, Khan H, Kaushik R, Khan MA. 2020. An assessment of potential nutritive and medicinal properties of Mucuna pruriens: a natural food legume. 3 Biotech. 10(6):1–15.
   PubMedGoogle Scholar
• Rai SN, Birla H, Zahra W, Singh SS, Singh SP. 2017. Immunomodulation of Parkinson’s disease using Mucuna pruriens (Mp). J Chem Neuroanat. 85:27–35.
   PubMed Web of Science ®Google Scholar
• Ray D, Pitts PB, Hogarth CA, Whitmore LS, Griswold MD, Ye P. 2014. Computer simulations of the mouse spermatogenic cycle. Biol Open. 4(1):1–12.
   PubMed Web of Science ®Google Scholar
• Redza-Dutordoir M, Averill-Bates DA. 2016. Activation of apoptosis signaling pathways by reactive oxygen species. Biochim Biophys Acta. 1863(12):2977–2992.
   PubMed Web of Science ®Google Scholar
• Saha S, Buttari B, Panieri E, Profumo E, Saso L. 2020. An overview of Nrf2 signaling pathway and its role in inflammation. Molecules. 25(22):5474–5431.
   PubMed Web of Science ®Google Scholar
• Sawatpanich T, Arun S, Tongpan S, Chaichun A, Sampannang A, Sukhorum W, Maneenin C, Burawat J, Iamsaard S. 2018. Localization and changes of tyrosine phosphorylated proteins and ß actin in epididymis of rats treated with valproic acid. Int J Morphol. 36(3):835–840.
   Web of Science ®Google Scholar
• Seppan P, Muhammed I, Mohanraj KG, Lakshmanan G, Premavathy D, Muthu SJ, Wungmarong Shimray K, Sathyanathan SB. 2020. Therapeutic potential of Mucuna pruriens (Linn.) on ageing induced damage in dorsal nerve of the penis and its implication on erectile function: an experimental study using albino rats. Aging Male. 23(5):313–326.
   PubMed Web of Science ®Google Scholar
• Shukla KK, Mahdi AA, Ahmad MK, Jaiswar SP, Shankwar SN, Tiwari SC. 2010. Mucuna pruriens reduces stress and improves the quality of semen in infertile men. Evid Based Complement Alternat Med. 7(1):137–144.
   PubMed Web of Science ®Google Scholar
• Shukla KK, Mahdi AA, Ahmad MK, Shankhwar SN, Rajender S, Jaiswar SP. 2009. Mucuna pruriens improves male fertility by its action on the hypothalamus-pituitary-gonadal axis. Fertil Steril. 92(6):1934–1940.
   PubMed Web of Science ®Google Scholar
• Sinha S, Sharma S, Vora J, Shah H, Srivastava A, Shrivastava N. 2018. Mucuna pruriens (L.) DC chemo sensitize human breast cancer cells via downregulation of prolactin-mediated JAK2/STAT5A signaling. J Ethnopharmacol. 217:23–35.
   PubMed Web of Science ®Google Scholar
• Skerrett-Byrne DA, Nixon B, Bromfield EG, Breen J, Trigg NA, Stanger SJ, Bernstein IR, Anderson AL, Lord T, Aitken RJ, et al. 2021. Transcriptomic analysis of the seminal vesicle response to the reproductive toxicant acrylamide. BMC Genomics. 22(1):1–22.
   PubMed Web of Science ®Google Scholar
• Stankiewicz AR, Lachapelle G, Foo CP, Radicioni SM, Mosser DD. 2005. Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation. J Biol Chem. 280(46):38729–38739.
   PubMed Web of Science ®Google Scholar
• Suresh S, Prakash S. 2012. Effect of Mucuna pruriens (Linn.) on sexual behavior and sperm parameters in streptozotocin-induced diabetic male rat. J Sex Med. 9(12):3066–3078.
   PubMed Web of Science ®Google Scholar
• Suresh S, Prithiviraj E, Prakash S. 2010. Effect of Mucuna pruriens on oxidative stress mediated damage in aged rat sperm. Int J Androl. 33(1):22–32.
   PubMedGoogle Scholar
• Tangsrisakda N, Kamollerd T, Taoto C, Bunsueb S, Chaimontri C, Choowong-In P, Lapyuneyong N, Wu AT, Thukhammee W, Wattanathorn J, et al. 2022. Seed extract of Thai Mucuna pruriens (L.) DC. var. pruriens enhances sexual performance and improves male reproductive damages in ethanol-induced rats. J Ethnopharmacol. 292:115219. 28
   PubMed Web of Science ®Google Scholar
• Tanji N, Satoh H, Takagi MY, Sugihara A, Terada N, Cunha GR, Yokoyama M. 2003. Induction of apoptosis by castration in epithelium of the mouse seminal vesicles. Arch Androl. 49(6):409–415.
   PubMed Web of Science ®Google Scholar
• Tongpan S, Sukhorum W, Arun S, Sawatphanich T, Iamsaard S. 2019. Valproic acid changes the expression of tyrosine-phosphorylated proteins in rat seminal vesicle. Andrologia. 51(7):e13303.
   PubMed Web of Science ®Google Scholar
• Vickram AS, Srikumar PS, Srinivasan S, Jeyanthi P, Anbarasu K, Thanigaivel S, Nibedita D, Jenila Rani D, Rohini K. 2021. Seminal exosomes - An important biological marker for various disorders and syndrome in human reproduction. Saudi J Biol Sci. 28(6):3607–3615.
   PubMed Web of Science ®Google Scholar
• Welsh M, Moffat L, Jack L, McNeilly A, Brownstein D, Saunders PT, Sharpe RM, Smith LB. 2010. Deletion of androgen receptor in the smooth muscle of the seminal vesicles impairs secretory function and alters its responsiveness to exogenous testosterone and estradiol. Endocrinology. 151(7):3374–3385.
   PubMed Web of Science ®Google Scholar
• Yannasithinon S, Iamsaard S. 2019. Alterations of morphology and phosphorylated protein expression in the seminal vesicles of diabetic mice. Andrologia. 51(10):e13406.
   PubMed Web of Science ®Google Scholar
• Zhang L, Pan J, Chen W, Jiang J, Huang J. 2020. Chronic stress-induced immune dysregulation in cancer: implications for initiation, progression, metastasis, and treatment. Am J Cancer Res. 10(5):1294–1307.
   PubMed Web of Science ®Google Scholar
• Zou P, Wang X, Yang W, Liu C, Chen Q, Yang H, Zhou N, Zeng Y, Chen H, Zhang G, et al. 2019. Mechanisms of stress-induced spermatogenesis impairment in male rats following unpredictable chronic mild stress (uCMS). Int J Mol Sci. 20:1–17.
   Web of Science ®Google Scholar