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Research Article

Da-Cheng-Qi decoction improves severe acute pancreatitis-associated acute lung injury by interfering with intestinal lymphatic pathway and reducing HMGB1-induced inflammatory response in rats

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Pages 144-154 | Received 28 Mar 2022, Accepted 14 Dec 2022, Published online: 09 Jan 2023

References

  • Besselink MG, van Santvoort HC, Renooij W, de Smet MB, Boermeester MA, Fischer K, Timmerman HM, Ahmed AU, Cirkel GA, Bollen TL, et al. 2009. Intestinal barrier dysfunction in a randomized trial of a specific probiotic composition in acute pancreatitis. Ann Surg. 250(5):712–719.
  • Boxhoorn L, Voermans RP, Bouwense SA, Bruno MJ, Verdonk RC, Boermeester MA, van Santvoort HC, Besselink MG. 2020. Acute pancreatitis. Lancet. 396(10252):726–734.
  • Cai J, Chen H, Weng M, Jiang S, Gao J. 2019. Diagnostic and clinical significance of serum levels of d-lactate and diamine oxidase in patients with Crohn’s disease. Gastroenterol Res Pract. 2019:8536952.
  • Chen K, Sun Y, Dong W, Zhang T, Zhou N, Yu W, Diao Y, Guo S, Tian Y. 2018. Activated Α7nachr improves postoperative cognitive dysfunction and intestinal injury induced by cardiopulmonary bypass in rats: inhibition of the proinflammatory response through the Th17 immune response. Cell Physiol Biochem. 46(3):1175–1188.
  • Chen Z, Chen Y, Pan L, Li HC, Tu JM, Liu C, Dai XQ, Zhang XF, Sun GF, Feng DX. 2015. Dachengqi decoction attenuates inflammatory response via inhibiting HMGB1 mediated NF-κB and P38 MAPK signaling pathways in severe acute pancreatitis. Cell Physiol Biochem. 37(4):1379–1389.
  • Christgen S, Kanneganti TD. 2021. Sepsis take-out: inhibiting bacterial deliveries. Immunity. 54(3):399–401.
  • Deitch EA. 2012. Gut-origin sepsis: evolution of a concept. Surgeon. 10(6):350–356.
  • Escobedo N, Oliver G. 2017. The lymphatic vasculature: its role in adipose metabolism and obesity. Cell Metab. 26(4):598–609.
  • Fusco R, Cordaro M, Siracusa R, D’Amico R, Genovese T, Gugliandolo E, Peritore AF, Crupi R, Impellizzeri D, Cuzzocrea S, et al. 2020. Biochemical evaluation of the antioxidant effects of hydroxytyrosol on pancreatitis-associated gut injury. Antioxidants. 9(9):781–798.
  • Ge P, Luo Y, Okoye CS, Chen H, Liu J, Zhang G, Xu C, Chen H. 2020. Intestinal barrier damage, systemic inflammatory response syndrome, and acute lung injury: a troublesome trio for acute pancreatitis. Biomed Pharmacother. 132:110770.
  • Guarneri F, Custurone P, Papaianni V, Gangemi S. 2021. Involvement of RAGE and oxidative stress in inflammatory and infectious skin diseases. Antioxidants. 10(1):82–95.
  • Haussner F, Chakraborty S, Halbgebauer R, Huber-Lang M. 2019. Challenge to the intestinal mucosa during sepsis. Front Immunol. 10:891–906.
  • He GZ, Dong LG, Chen XF, Zhou KG, Shu H. 2011. Lymph duct ligation during ischemia/reperfusion prevents pulmonary dysfunction in a rat model with ω-3 polyunsaturated fatty acid and glutamine. Nutrition. 27(5):604–614.
  • Huang L, Zhang D, Han W, Guo C. 2019. High-mobility group box-1 inhibition stabilizes intestinal permeability through tight junctions in experimental acute necrotizing pancreatitis. Inflamm Res. 68(8):677–689.
  • Huang Z, Ma X, Jia X, Wang R, Liu L, Zhang M, Wan X, Tang C, Huang L. 2020. Prevention of severe acute pancreatitis with cyclooxygenase-2 inhibitors: a randomized controlled clinical trial. Am J Gastroenterol. 115(3):473–480.
  • Imanaka H, Shimaoka M, Matsuura N, Nishimura M, Ohta N, Kiyono H. 2001. Ventilator-induced lung injury is associated with neutrophil infiltration, macrophage activation, and TGF-beta 1 mRNA upregulation in rat lungs. Anesth Analg. 92(2):428–436.
  • Jabaudon M, Blondonnet R, Roszyk L, Pereira B, Guérin R, Perbet S, Cayot S, Bouvier D, Blanchon L, Sapin V, et al. 2015. Soluble forms and ligands of the receptor for advanced glycation end-products in patients with acute respiratory distress syndrome: an observational prospective study. PLoS One. 10(8):e0135857.
  • Jin W, Shen Y. 2019. Da-Cheng-Qi decoction Alleviates intestinal injury in rats with severe acute pancreatitis by inhibiting the JAK2-STAT3 signaling pathway. Evid Based Complement Alternat Med. 2019:3909468.
  • Kang R, Zhang Q, Hou W, Yan Z, Chen R, Bonaroti J, Bansal P, Billiar TR, Tsung A, Wang Q, et al. 2014. Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice. Gastroenterology. 146(4):1097–1107.
  • Kim J, Choo S, Sim H, Baek MC, Bae JS. 2021. Biapenem reduces sepsis mortality via barrier protective pathways against HMGB1-mediated septic responses. Pharmacol Rep. 73(3):786–795.
  • Kong W, Wang J, Ping X, Shen J, Ni X, Liu F, Yu B, Li Y. 2015. Biomarkers for assessing mucosal barrier dysfunction induced by chemotherapy: identifying a rapid and simple biomarker. Clin Lab. 61(3-4):371–378.
  • Kubisch C, Dimagno MJ, Tietz AB, Welsh MJ, Ernst SA, Brandt-Nedelev B, Diebold J, Wagner AC, Göke B, Williams JA, et al. 2004. Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. Gastroenterology. 127(1):275–286.
  • Li XY, He C, Zhu Y, Lu NH. 2020. Role of gut microbiota on intestinal barrier function in acute pancreatitis. World J Gastroenterol. 26(18):2187–2193.
  • Lichtman SM. 2001. Bacterial [correction of baterial] translocation in humans. J Pediatr Gastroenterol Nutr. 33(1):1–10.
  • Liu J, Huang L, Luo M, Xia X. 2019. Bacterial translocation in acute pancreatitis. Crit Rev Microbiol. 45(5-6):539–547.
  • Mittal A, Hickey AJ, Chai CC, Loveday Benjamin PT, Thompson N, Dare A, Delahunt B, Cooper GJ, Windsor JA, Phillips AR. 2011. Early organ-specific mitochondrial dysfunction of jejunum and lung found in rats with experimental acute pancreatitis. HPB. 13(5):332–341.
  • Pan LY, Chen YF, Li HC, Bi LM, Sun WJ, Sun GF, Zhang XF, Xu K, Feng DX. 2017. Dachengqi decoction attenuates intestinal vascular endothelial injury in severe acute pancreatitis in vitro and in vivo. Cell Physiol Biochem. 44(6):2395–2406.
  • Qin HL, Su ZD, Hu LG, Ding ZX, Lin QT. 2002. Effect of early intrajejunal nutrition on pancreatic pathological features and gut barrier function in dogs with acute pancreatitis. Clin Nutr. 21(6):469–473.
  • Reed HO, Wang LQ, Sonett J, Chen M, Yang JS, Li L, Aradi P, Jakus Z, D'Armiento J, Hancock WW, et al. 2019. Lymphatic impairment leads to pulmonary tertiary lymphoid organ formation and alveolar damage. J Clin Invest. 129(6):2514–2526.
  • Schietroma M, Pessia B, Colozzi S, Carlei F, Amicucci G. 2018. Does bacterial translocation influence the postoperative infections in splenectomized patients after abdominal trauma? Surgeon. 16(2):94–100.
  • Senthil M, Watkins A, Barlos D, Xu DZ, Lu Q, Abungu B, Caputo F, Feinman R, Deitch EA. 2007. Intravenous injection of trauma-hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway. Ann Surg. 246(5):822–830.
  • Shanbhag ST, Choong B, Petrov M, Delahunt B, Windsor JA, Phillips Anthony RJ. 2018. Acute pancreatitis conditioned mesenteric lymph causes cardiac dysfunction in rats independent of hypotension. Surgery. 163(5):1097–1105.
  • Shi Z, Wang Y, Ye W, Lin Z, Deng T, Zhang T, Zhao J, Tong Y, Shan Y, Chen G. 2021. The LipoxinA4 receptor agonist BML-111 ameliorates intestinal disruption following acute pancreatitis through the Nrf2-regulated antioxidant pathway. Free Radic Biol Med. 163:379–391.
  • Song WB, Lv YH, Zhang ZS, Li YN, Xiao LP, Yu XP, Wang YY, Ji HL, Ma L. 2009. Soluble intercellular adhesion molecule-1, d-lactate and diamine oxidase in patients with inflammatory bowel disease. World J Gastroenterol. 15(31):3916–3919.
  • Su S, Liang T, Zhou X, He K, Li B, Xia X. 2019. Qingyi decoction attenuates severe acute pancreatitis in rats via inhibition of inflammation and protection of the intestinal barrier. J Int Med Res. 47(5):2215–2227.
  • Sun W, Chen Y, Li H, Liu H, Li J, Chen J, Feng D. 2020. Material basis and molecular mechanisms of Dachengqi decoction in the treatment of acute pancreatitis based on network pharmacology. Biomed Pharmacother. 121:109656.
  • Takeuchi T, Kitagawa H, Harada E. 2004. Evidence of lactoferrin transportation into blood circulation from intestine via lymphatic pathway in adult rats. Exp Physiol. 89(3):263–270.
  • Tang CH, Keng YT, Liu JF. 2012. HMGB-1 induces cell motility and α5β1 integrin expression in human chondrosarcoma cells. Cancer Lett. 322(1):98–106.
  • Tang Y, Kong J, Zhou B, Wang X, Liu X, Wang Y, Zhu S. 2021. Mesenteric lymph duct ligation alleviates acute lung injury caused by severe acute pancreatitis through inhibition of high mobility group box 1- induced inflammation in rats. Dig Dis Sci. 66(12):4344–4353.
  • Tang Y, Wang X, Li Z, He Z, Yang X, Cheng X, Peng Y, Xue Q, Bai Y, Zhang R, et al. 2021. Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties. Immunity. 54(3):454–467.e6.
  • Úbeda M, Lario M, Muñoz L, Borrero MJ, Rodríguez-Serrano M, Sánchez D, Del CR, Lledó L, Pastor Ó, García-Bermejo L, et al. 2016. Obeticholic acid reduces bacterial translocation and inhibits intestinal inflammation in cirrhotic rats. J Hepatol. 64(5):1049–1057.
  • Wu LM, Sankaran SJ, Plank LD, Windsor JA, Petrov MS. 2014. Meta-analysis of gut barrier dysfunction in patients with acute pancreatitis. Br J Surg. 101(13):1644–1656.
  • Xiong Y, Chen L, Fan L, Wang L, Zhou Y, Qin D, Sun Q, Wu J, Cao S. 2018. Free total rhubarb anthraquinones protect intestinal injury via regulation of the intestinal immune response in a rat model of severe acute pancreatitis. Front Pharmacol. 9:75–87.
  • Xu J, Jiang Y, Wang J, Shi X, Liu Q, Liu Z, Li Y, Scott MJ, Xiao G, Li S, et al. 2014. Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis. Cell Death Differ. 21(8):1229–1239.
  • Yang C, Zhang X, Wang S, Huo X, Wang J. 2021. Small intestinal bacterial overgrowth and evaluation of intestinal barrier function in patients with ulcerative colitis. Am J Transl Res. 13(6):6605–6610.
  • Yang H, Wang H, Andersson U. 2020. Targeting inflammation driven by HMGB1. Front Immunol. 11:484–492.
  • Yao D, Brownlee M. 2010. Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands. Diabetes. 59(1):249–255.
  • Yuan J, Tan T, Geng M, Tan G, Chheda C, Pandol Stephen J. 2017. Novel small molecule inhibitors of protein kinase D suppress NF-kappaB activation and attenuate the severity of rat cerulein pancreatitis. Front Physiol. 8:1014–1026.
  • Yuan L, Zhu L, Zhang Y, Chen H, Kang H, Li J, Zhao X, Wan M, Miao Y, Tang W. 2018. Effect of Da-Cheng-Qi decoction for treatment of acute kidney injury in rats with severe acute pancreatitis. Chin Med. 13:38–45.
  • Zhang J, Yu WQ, Wei T, Zhang C, Wen L, Chen Q, Chen W, Qiu JY, Zhang Y, Liang TB. 2020. Effects of short-peptide-based enteral nutrition on the intestinal microcirculation and mucosal barrier in mice with severe acute pancreatitis. Mol Nutr Food Res. 64(5):e1901191.
  • Zhang Y, Shao F, Guan Z, Luo J, Xiao X, Zhou L. 2021. Overexpression of miR-99a alleviates intestinal mucosal barrier injury in rats with severe acute pancreatitis. J Interferon Cytokine Res. 41(2):72–80.
  • Zhang YM, Ren HY, Zhao XL, Li J, Li JY, Wu FS, Su H, Tang WF. 2017. Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis. World J Gastroenterol. 23(8):1367–1374.
  • Zhao J, Chen J, Tang W, Wan L, Xiong W, Zhou L. 2011. Effect of Da-Cheng-Qi decoction on pancreatitis-associated lung injury in patients and anti-inflammatory responses in rat models. Pharm Biol. 49(10):1058–1064.
  • Zhao J, Zhong C, He Z, Chen G, Tang W. 2015. Effect of Da-Cheng-Qi decoction on pancreatitis-associated intestinal dysmotility in patients and in rat models. Evid Based Complement Alternat Med. 2015:895717–895717.