Ligustrazine inhibits inflammatory response of human endometrial stromal cells through the STAT3/IGF2BP1/RELA axis

References

• Bian Y, Yuan L, Yang X, Weng L, Zhang Y, Bai H, Chen J. 2021. SMURF1-mediated ubiquitylation of SHP-1 promotes cell proliferation and invasion of endometrial stromal cells in endometriosis. Ann Transl Med. 9(5):362–362.
   PubMed Web of Science ®Google Scholar
• Chowdhury I, Banerjee S, Driss A, Xu W, Mehrabi S, Nezhat C, Sidell N, Taylor RN, Thompson WE. 2019. Curcumin attenuates proangiogenic and proinflammatory factors in human eutopic endometrial stromal cells through the NF-κB signaling pathway. J Cell Physiol. 234(5):6298–6312.
   PubMed Web of Science ®Google Scholar
• Cruz-Zaragoza LD, Dennerlein S, Linden A, Yousefi R, Lavdovskaia E, Aich A, Falk RR, Gomkale R, Schöndorf T, Bohnsack MT, et al. 2021. An in vitro system to silence mitochondrial gene expression. Cell. 184(23):5824–5837.e15.
   PubMed Web of Science ®Google Scholar
• Gao M, Liu L, Zhang X, Li Z, Zhang M. 2021. Interleukin-6 reverses adriamycin resistance in nasal NK/T-cell lymphoma via downregulation of ABCC4 and inactivation of the JAK2/STAT3/NF-κB/P65 pathway. Environ Toxicol Pharmacol. 85:103639.
   PubMed Web of Science ®Google Scholar
• He Y, Hung SW, Liang B, Zhang R, Gao Y, Chu CY, Zhang T, Xu H, Chung JPW, Wang CC. 2021. Receptor tyrosine kinase inhibitor sunitinib as novel immunotherapy to inhibit myeloid-derived suppressor cells for treatment of endometriosis. Front Immunol. 12:641206.
   PubMed Web of Science ®Google Scholar
• Huan Q, Cheng SC, Du ZH, Ma HF, Li C. 2021. LncRNA AFAP1-AS1 regulates proliferation and apoptosis of endometriosis through activating STAT3/TGF-β/Smad signaling via miR-424-5p. J Obstet Gynaecol Res. 47(7):2394–2405.
   PubMed Web of Science ®Google Scholar
• Jiang R, Xu J, Zhang Y, Zhu X, Liu J, Tan Y. 2021. Ligustrazine alleviate acute lung injury through suppressing pyroptosis and apoptosis of alveolar macrophages. Front Pharmacol. 12:680512.
   PubMed Web of Science ®Google Scholar
• Khawaja H, Fazal N, Yaqub F, Ahmad MR, Hanif M, Yousaf MA, Latief N. 2021. Protective and proliferative effect of Aesculus indica extract on stressed human adipose stem cells via downregulation of NF-κB pathway. PLoS One. 16(10):e0258762.
   PubMed Web of Science ®Google Scholar
• Kotlyar AM, Mamillapalli R, Flores VA, Taylor HS. 2021. Tofacitinib alters STAT3 signaling and leads to endometriosis lesion regression. Mol Hum Reprod. 27:gaab016.
   PubMed Web of Science ®Google Scholar
• Li L, Liao Z, Ye M, Jiang J. 2021. Recombinant human IL-37 inhibited endometriosis development in a mouse model through increasing Th1/Th2 ratio by inducing the maturation of dendritic cells. Reprod Biol Endocrinol. 19(1):128.
   PubMed Web of Science ®Google Scholar
• Li X, Xiong W, Long X, Dai X, Peng Y, Xu Y, Zhang Z, Zhang L, Liu Y. 2021. Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis†. Biol Reprod. 105(5):1221–1233.
   PubMed Web of Science ®Google Scholar
• Liu HT, Zou YX, Zhu WJ, Sen L, Zhang GH, Ma RR, Guo XY, Gao P. 2022. LncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus. Cell Death Differ. 29(3):627–641.
   PubMed Web of Science ®Google Scholar
• Liu M, Tao G, Cao Y, Hu Y, Zhang Z. 2022. Silencing of IGF2BP1 restrains ox-LDL-induced lipid accumulation and inflammation by reducing RUNX1 expression and promoting autophagy in macrophages. J Biochem Mol Toxicol. 36(4):e22994.
   PubMed Web of Science ®Google Scholar
• Ma X, Ruan Q, Ji X, Yang J, Peng H. 2021. Ligustrazine alleviates cyclophosphamide-induced hepatotoxicity via the inhibition of Txnip/Trx/NF-κB pathway. Life Sci. 274:119331.
   PubMed Web of Science ®Google Scholar
• Miller JE, Lingegowda H, Symons LK, Bougie O, Young SL, Lessey BA, Koti M, Tayade C. 2021. IL-33 activates group 2 innate lymphoid cell expansion and modulates endometriosis. JCI Insight. 6(23):e149699.
   PubMed Web of Science ®Google Scholar
• Ramesh-Kumar D, Guil S. 2022. The IGF2BP family of RNA binding proteins links epitranscriptomics to cancer. Semin Cancer Biol. 86(Pt 3):18–31.
   Google Scholar
• Sansone AM, Hisrich BV, Young RB, Abel WF, Bowens Z, Blair BB, Funkhouser AT, Schammel DP, Green LJ, Lessey BA, et al. 2021. Evaluation of BCL6 and SIRT1 as non-invasive diagnostic markers of endometriosis. Curr Issues Mol Biol. 43(3):1350–1360.
   PubMed Web of Science ®Google Scholar
• Shafrir AL, Martel E, Missmer SA, Clauw DJ, Harte SE, As-Sanie S, Sieberg CB. 2021. Pelvic floor, abdominal and uterine tenderness in relation to pressure pain sensitivity among women with endometriosis and chronic pelvic pain. Eur J Obstet Gynecol Reprod Biol. 264:247–253.
   PubMed Web of Science ®Google Scholar
• Veena KV, Siddamalla S, Deenadayal M, Shivaji S, Bhanoori M. 2022. DNMT1 and DNMT3B gene variants and their association with endometriosis in South Indian women. Mol Biol Rep. 49(1):321–329.
   PubMed Web of Science ®Google Scholar
• Wu J, Fang X, Xia X. 2021. Identification of key genes and pathways associated with endometriosis by weighted gene co-expression network analysis. Int J Med Sci. 18(15):3425–3436.
   PubMed Web of Science ®Google Scholar
• Xie J, Li Q, Zhu XH, Gao Y, Zhao WH. 2019. IGF2BP1 promotes LPS-induced NFκB activation and pro-inflammatory cytokines production in human macrophages and monocytes. Biochem Biophys Res Commun. 513(4):820–826.
   PubMed Web of Science ®Google Scholar
• Yi YC, Wang SC, Chao CC, Su CL, Lee YL, Chen LY. 2010. Evaluation of serum autoantibody levels in the diagnosis of ovarian endometrioma. J Clin Lab Anal. 24(5):357–362.
   PubMed Web of Science ®Google Scholar
• Yu H, Zhong Q, Xia Y, Li E, Wang S, Ren R. 2019. MicroRNA-2861 targets STAT3 and MMP2 to regulate the proliferation and apoptosis of ectopic endometrial cells in endometriosis. Pharmazie. 74:243–249.
   PubMed Web of Science ®Google Scholar
• Zhang C, Zhang Y, Pan H, Tan Y, Wei Q, Dai X, Wei J, Chen Y. 2021. Combination of ferulic acid, ligustrazine and tetrahydropalmatine attenuates epithelial-mesenchymal transformation via Wnt/β-catenin pathway in endometriosis. Int J Biol Sci. 17(10):2449–2460.
   PubMed Web of Science ®Google Scholar
• Zhang F, Jin H, Wu L, Shao J, Wu X, Lu Y, Zheng S. 2016. Ligustrazine disrupts lipopolysaccharide-activated NLRP3 inflammasome pathway associated with inhibition of Toll-like receptor 4 in hepatocytes. Biomed Pharmacother. 78:204–209.
   PubMed Web of Science ®Google Scholar
• Zhang L, Lu X, Gong L, Cui L, Zhang H, Zhao W, Jiang P, Hou G, Hou Y. 2021. Tetramethylpyrazine protects blood-spinal cord barrier integrity by modulating microglia polarization through activation of STAT3/SOCS3 and inhibition of NF-кB signaling pathways in experimental autoimmune encephalomyelitis mice. Cell Mol Neurobiol. 41(4):717–731.
   PubMed Web of Science ®Google Scholar
• Zhang M, Lu N, Li HJ, Guo XY, Lu L, Guo Y. 2022. Inhibition of lncRNA NEAT1 induces dysfunction of fibroblast-like synoviocytes in rheumatoid arthritis via miRNA-338-3p-mediated regulation of glutamine metabolism. J Orthop Surg Res. 17(1):401.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Li M, Li L, Xiao J, Chen Z. 2021. Randomized controlled study of the effects of DHEA on the outcome of IVF in endometriosis. Evid Based Complement Alternat Med. 2021:3569697.
   PubMedGoogle Scholar