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Research Article

Qiqilian ameliorates vascular endothelial dysfunction by inhibiting NLRP3-ASC inflammasome activation in vivo and in vitro

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Pages 815-824 | Received 26 Aug 2022, Accepted 25 Apr 2023, Published online: 17 May 2023

References

  • Bal NB, Bostanci A, Sadi G, Donmez MO, Uludag MO, Demirel-Yilmaz E. 2022. Resveratrol and regular exercise may attenuate hypertension-induced cardiac dysfunction through modulation of cellular stress responses. Life Sci. 296:120424.
  • Baumbach GL, Heistad DD. 1989. Remodeling of cerebral arterioles in chronic hypertension. Hypertension. 13(6 Pt 2):968–972.
  • Bian F, Cui J, Zheng T, Jin S. 2017. Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells. Int J Mol Med. 39(3):629–635.
  • Denton D, Xu T, Kumar S. 2015. Autophagy as a pro-death pathway. Immunol Cell Biol. 93(1):35–42.
  • Deretic V, Saitoh T, Akira S. 2013. Autophagy in infection, inflammation and immunity. Nat Rev Immunol. 13(10):722–737.
  • Dharmashankar K, Widlansky ME. 2010. Vascular endothelial function and hypertension: insights and directions. Curr Hypertens Rep. 12(6):448–455.
  • Dimmeler S, Rippmann V, Weiland U, Haendeler J, Zeiher AM. 1997. Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide. Circ Res. 81(6):970–976.
  • Fei YX, Zhao B, Yin QY, Qiu YY, Ren GH, Wang BW, Wang YF, Fang WR, Li YM. 2019. Ma Xing Shi Gan decoction attenuates PM2.5 induced lung injury via inhibiting HMGB1/TLR4/NFkappaB signal pathway in rat. Front Pharmacol. 10:1361.
  • Hao P, Jiang F, Cheng J, Ma L, Zhang Y, Zhao Y. 2017. Traditional Chinese medicine for cardiovascular disease: evidence and potential mechanisms. J Am Coll Cardiol. 69(24):2952–2966.
  • Hao PP, Jiang F, Chen YG, Yang J, Zhang K, Zhang MX, Zhang C, Zhao YX, Zhang Y. 2015. Traditional Chinese medication for cardiovascular disease. Nat Rev Cardiol. 12(6):318.
  • Hu R, Wang MQ, Ni SH, Wang M, Liu LY, You HY, Wu XH, Wang YJ, Lu L, Wei LB. 2020. Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-kappaB/NLRP3 signaling pathway in AGEs-induced HUVECs. Eur J Pharmacol. 867:172797.
  • Huang PP, Fu J, Liu LH, Wu KF, Liu HX, Qi BM, Liu Y, Qi BL. 2020. Honokiol antagonizes doxorubicin-induced cardiomyocyte senescence by inhibiting TXNIPmediated NLRP3 inflammasome activation. Int J Mol Med. 45(1):186–194.
  • Kim KH, Lee MS. 2014. Autophagy–a key player in cellular and body metabolism. Nat Rev Endocrinol. 10(6):322–337.
  • Li H, Xiao L, He H, Zeng H, Liu J, Jiang C, Mei G, Yu J, Chen H, Yao P, et al. 2021. Quercetin attenuates atherosclerotic inflammation by inhibiting galectin-3-NLRP3 signaling pathway. Mol Nutr Food Res. 65(15):e2000746.
  • Li L, Tan J, Miao Y, Lei P, Zhang Q. 2015. ROS and autophagy: interactions and molecular regulatory mechanisms. Cell Mol Neurobiol. 35(5):615–621.
  • Liu D, Sun WP, Chen JW, Jiang Y, Xue R, Wang LH, Murao K, Zhang GX. 2021. Autophagy contributes to angiotensin II induced dysfunction of HUVECs. Clin Exp Hypertens. 43(5):462–473.
  • Liu D, Zeng X, Li X, Mehta JL, Wang X. 2018. Role of NLRP3 inflammasome in the pathogenesis of cardiovascular diseases. Basic Res Cardiol. 113(1):5.
  • Liu Q, Zhang D, Hu D, Zhou X, Zhou Y. 2018. The role of mitochondria in NLRP3 inflammasome activation. Mol Immunol. 103:115–124.
  • Long L, Yang X, Southwood M, Lu J, Marciniak SJ, Dunmore BJ, Morrell NW. 2013. Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation. Circ Res. 112(8):1159–1170.
  • Luo Y, Yue GH, Yun YE, Lei FU. 2015. Protective effect of qiqilian capsule against left ventricular hypertrophy of spontaneously hypertensive rats. Chin J Exper Trad Med Form. 21:116–120.
  • Mirabito Colafella KM, Danser AHJ. 2017. Recent advances in angiotensin research. Hypertension. 69(6):994–999.
  • NCD Risk Factor Collaboration (NCD-RisC). 2021. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 398(10304):957–980.
  • Qin Y, Zhu Z, Zhang A, Yue G. 2013. Effect of Qiqilian capsule on life quality of hypertension patients. Jiangsu J Trad Chin Med. 45:25–27.
  • Silva BR, Pernomian L, Bendhack LM. 2012. Contribution of oxidative stress to endothelial dysfunction in hypertension. Front Physiol. 3:441.
  • Sun C, Diao Q, Lu J, Zhang Z, Wu D, Wang X, Xie J, Zheng G, Shan Q, Fan S, et al. 2019. Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence. J Cell Physiol. 234(5):5926–5939.
  • Sun HJ, Ren XS, Xiong XQ, Chen YZ, Zhao MX, Wang JJ, Zhou YB, Han Y, Chen Q, Li YH, et al. 2017. NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension. Cell Death Dis. 8(10):e3074.
  • Sun Y, Lu M, Sun T, Wang H. 2021. Astragaloside IV attenuates inflammatory response mediated by NLRP-3/calpain-1 is involved in the development of pulmonary hypertension. J Cell Mol Med. 25(1):586–590.
  • Tang B, Chen GX, Liang MY, Yao JP, Wu ZK. 2015. Ellagic acid prevents monocrotaline-induced pulmonary artery hypertension via inhibiting NLRP3 inflammasome activation in rats. Int J Cardiol. 180:134–141.
  • Tian X, Zhao X, Liu D, Zhang Y, Qu L, Wu P, He L. 2018. Effect of chloroquine in angiotensin II induced vascular remodeling in mice. J Clin Pathol Res. 38:1595–1600.
  • Vanhoutte PM, Shimokawa H, Tang EH, Feletou M. 2009. Endothelial dysfunction and vascular disease. Acta Physiol. 196(2):193–222.
  • Wang R, Liu L, Liu H, Wu K, Liu Y, Bai L, Wang Q, Qi B, Qi B, Zhang L. 2019. Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging. Aging (Albany NY). 11(17):7021–7035.
  • Whiteford JR, D, Rossi G, Woodfin A. 2016. Mutually supportive mechanisms of inflammation and vascular remodeling. Int Rev Cell Mol Biol. 326:201–278.
  • Xue Z, Li Y, Zhou M, Liu Z, Fan G, Wang X, Zhu Y, Yang J. 2021. Traditional herbal medicine discovery for the treatment and prevention of pulmonary arterial hypertension. Front Pharmacol. 12:720873.
  • Yue G, Mo L, Luo Y. 2010. Effect of Yiqihuoxuejiedu decoction on inflammatory factor and von Willebrand factor of spontaneously hypertensive pressure rats. J Emerg Tradit Chin Med. 19:1365–1367.
  • Zhang Z, Yue G. 2012. Protective effects of Yiqi Huoxue Jiedu recipe on the function of blood vessel endothelium in spontaneous hypertension rats. China Pharmacy. 23:200–202.
  • Zhao N, Yang FE, Zhao CY, Lv SW, Wang J, Liu JM, Wang S. 2021. Construction of pH-dependent nanozymes with oxygen vacancies as the high-efficient reactive oxygen species scavenger for oral-administrated anti-inflammatory therapy. Adv Healthc Mater. 10(23):e2101618.
  • Zhao ZQ, Zhang BL, Chu HQ, Liang L, Chen BZ, Zheng H, Guo XD. 2022. A high-dosage microneedle for programmable lidocaine delivery and enhanced local long-lasting analgesia. Biomater Adv. 133:112620.
  • Zhou R, Yazdi AS, Menu P, Tschopp J. 2011. A role for mitochondria in NLRP3 inflammasome activation. Nature. 469(7329):221–225.
  • Zhou W, Chen C, Chen Z, Liu L, Jiang J, Wu Z, Zhao M, Chen Y. 2018. NLRP3: a novel mediator in cardiovascular disease. J Immunol Res. 2018:5702103.