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Review

The traditional herb Polygonum hydropiper from China: a comprehensive review on phytochemistry, pharmacological activities and applications

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Pages 799-814 | Received 19 Nov 2022, Accepted 24 Apr 2023, Published online: 17 May 2023

References

  • Ao LL. 2019. Self- made environment-friendly and efficient plane pesticide (1). Ke Xue Zhong Yang. (2):40–42.
  • Ayaz M, Junaid M, Ullah F, Sadiq A, Azam M, Waqar K, Muhammad A, Shah R, Sajjad I. 2015. Comparative chemical profiling, cholinesterase inhibitions and anti-radicals properties of essential oils from Polygonum hydropiper L: a preliminary anti-Alzheimer’s study. Lipids Health Dis. 14:141–153.
  • Ayaz M, Junaid M, Ullah F, Sadiq A, Shahid M, Ahmad W, Ullah I, Ahmad A, Syed NH. 2017. GC-MS Analysis and gastroprotective evaluations of crude extracts, isolated saponins, and essential oil from Polygonum hydropiper L. Front Chem. 5:58–68.
  • Ayaz M, Junaid M, Ullah F, Subhan F, Sadiq A, Ali G, Ovais M, Shahid M, Ahmad A, Wadood A, et al. 2017. Anti-Alzheimer’s studies on β-sitosterol isolated from Polygonum hydropiper L. Front Pharmacol. 8:697.
  • Ayaz M, Sadiq A, Wadood A, Junaid M, Ullah F, Khan NZ. 2019. Cytotoxicity and molecular docking studies on phytosterols isolated from Polygonum hydropiper L. Steroids. 141:30–35.
  • Cao HL. 2006. Observation on the killing effect of different concentrations of Polygonum hydropiper on the larvar of Culex vulgaris. Chin J Vector Biol Control. 6:464.
  • Chen CL, Zheng H, Cao GW, Li CH. 2012. Experiment on the antibacterial effect of compound Polygonum hydropiper on Escherichia coli. Shanghai J Anim Husb Vet Med. 3:52.
  • Chen JZ, Tan JC, Li XW, Zeng WA, Yang JL. 2007. Bioactivity of the Polygonum hydropiper L. extracts against Ectropis obliqua Prout. J Tea Commun. 1:7–9.
  • Cheng ZN, Li CY, Huang CJ. 1999. China’99 Kunming world horticultural expo horticultural encyclopedia. Beijing: China Forestry Press.
  • Cheng ZH, Liu YH, Cao H, Li R, Song BZ, Li SC. 2014. Studies on acaricidal bioactivities of six plants extracts against the Tetranychus Cinnabarinus Bois. J Shanxi Agric Univ (Nat Sci Ed). 34:403–406.
  • Daniyal M, Akram M. 2015. Antifertility activity of medicinal plants. J Chin Med Assoc. 78(7):382–388.
  • Devarajan S, Yahiro E, Uehara Y, Kuroda R, Hirano Y, Nagata K, Miura S, Saku K, Urata H. 2018. Depressor effect of the young leaves of Polygonum hydropiper Linn. in high-salt induced hypertensive mice. Biomed Pharmacother. 102:1182–1187.
  • Fukuyama Y, Sato T, Asakawa Y, Takemoto T. 1980. A potent cytotoxic warburganal and related drimane-type. sesquiterpenoids from Polygonum hydropiper. Pergamon. 21(12):2895–2898.
  • Fukuyama Y, Sato T, Miura I, Asakawa Y. 1985. Drimane-type sesqui- and norsesquiterpenoids from Polygonum hydropiper. Planta Med. 77:1848–1851.
  • Fukuyama Y, Sato T, Miura I, Asakawa Y, Takemoto T. 1983. Hydropiperside, a novel coumaryl glycoside from the root of Polygonum hydropiper. Phytochemistry. 22(2):549–552.
  • Goswami P, Hazarika A, Sarma HN. 2014. Inhibition of Insulin like growth factor-I expression by chromatographic fraction of Polygonum hydropiper root reduces implantation preference in rat. Middle East Fertility Soc J. 19(1):34–41.
  • Gu LY, Tao JY, Wu WY, Song ML, Hu TJ. 2018. Effects of FEA from Polygonum hydropiper L. on biochemical indexes and inflammatory cytokines in mice with endotoxemia induced by lipopolysaccharide. Chin J Inf Tradit Chin Med. 25(04):40–45.
  • Gu LY, Tao JY, Yang J, Zeng Y, Wei YY, Hu TJ. 2018. Protective effects of FNB from Polygonum hydropiper on endotoxemia induced by lipopolysaccharides in mice. Prog Vet Med. 39(02):84–90.
  • Guan JY, Li L, Yu ML, Wei YY, Hu TJ. 2021. Study on effect of anti-inflammatory of flavonoids from Polygonum hydropiper L. in mice. Mod J Anim Husb Vet Med. 2:1–4.
  • Haraguchi H, Hashimoto K, Yagi A. 1992. Antioxidative substances in leaves of Polygonum hydropiper. J Agric Food Chem. 40(8):1349–1351.
  • Haraguchi H, Matsuda R, Hashimoto K. 1993. High-performance liquid chromatographic determination of sesquiterpene dialdehydes and antifungal activity from Polygonum hydropiper. J Agric Food Chem. 41(1):5–7.
  • Haraguchi H, Ohmi I, Sakai S, Fukuda A, Toihara Y, Fujimoto T, Okamura N, Yagi A. 1996. Effect of Polygonum hydropiper flavonoids on lens aldose reductase and related enzymes. J Nat Prod. 59(4):443–445.
  • He LM, Chen YT, Liu HM, Peng XY, Pan YF, Yuan MG, Luo SJ, Wei GW. 2014. Simultaneous determination of six kinds of flavonoid in extract of Polygonum hydropiper L. by HPLC. Guangdong Agric Sci. 41(13):94–98.
  • Huang HH, Zhen HS. 2013. Recent research progress of the Chinese herb Polygonum hydropiper. Chin J Ethnomed Ethnopharm. 22(01):38–40.
  • Huang J, Hou PY, Wu LJ, Gao HY. 2012. Isolation and identification of chemical constituents of Polygonum hydropiper. J Shenyang Pharm Univ. 29(01):22–25.
  • Huang JH, Yue L, Zhang MR, Yang Q, Cheng XX. 2022. Effects of Polygonum hydropiper on the expressions of inflammatory cytokines and cytochrome P450 enzymes in mice with E. coli-induced diarrhea. J Chin Pharm Sci. 31:622–633.
  • Kiem PV, Nhiem NX, Cuong NX, Hoa TQ, Huong HT, Huong LM, Minh CV, Kim YH. 2008. New phenylpropanoid esters of sucrose from. Polygonum hydropiper and their antioxidant activity. Arch Pharm Res. 31(11):1477–1482.
  • Kurkina AV, Ryazanova TK, Kurkin VA. 2013. Flavonoids from the aerial part of Polygonum hydropiper. Chem Nat Compd. 49(5):830–832.
  • Lai WY, Yang WL, Liu MS, Zhang JQ. 2011. Detection of heavy metal contents in four li nationality medicine. China Trop Med. 11:579–581.
  • Li AR, Bao BJ, Alisa EGB. 2003. Urticaceae (Flora of China). Beijing: Science Press, Beijing & Missouri Botanical, Garden Press. p. 277–278.
  • Li M, Liu XF, Zhang KF. 2014. Effect of Polygonum perfoliatum L. on the expression of HBsAg and HBeAg in HepG2. 2.15 cells. Chin J Ethnomed Ethnopharm. 23(13):2–3.
  • Li MY. 2017. Chemical compositions of Polygonum hydropiper L. and their bioactivities [master’s thesis]. Xi’an: shanxi Univ Sci Technol.
  • Li MY, Ma YM, Qiao K, Guo LX. 2017. Chemical constituents from Polygonum hydropiper. Chin Tradit Pat Med. 39:769–773.
  • Li Q. 2007. Extraction, analysis of chemical composition and determination of insecticidal activity of volatile oil from Polygonum hydropiper [master’s thesis]. Zhanzhou: south China Univ Trop Agr.
  • Li Q, Gu ZX. 2018. Gu Zhongxin’s clinical experience in treating cyst with Polygonum hydropiper and Gardenia jasminoides Ellis. China’s Naturop. 26(11):14–15.
  • Lin CM, Wang DP, Cui FZ, Zhu HY, Yang XS. 2012. Volatile components of Polygonum hydropiper distributed in Guizhou Province. Guihaia. 32(03):410–414.
  • Lin YW. 2011. Antibacterial experiment of two Polygonaceae plants in vitro. J Microbiol. 31(03):102–105.
  • Liu FR. 2017. Chinese herbal medicine for fishery (2). Hunan Agric. 8:25.
  • Liu MQ, Tao JY, Hu WY, Wei YY, Hu TJ. 2021. Anti-inflammatory mechanism of FEA from Polygonum hydropiper L. in LPS-treated RAW264.7 cells. Prog Vet Med. 42(06):40–45.
  • Liu QF, Luyten W, Pellens K, Wang YM, Wang W, Thevissen K, Liang QL, Cammue BPA, Schoofs L, Luo GA. 2012. Antifungal activity in plants from Chinese traditional and folk medicine. J Ethnopharmacol. 143(3):772–778.
  • Liu SQ, Wang GR. 2017. Prevention and control techniques of fish diseases in spring. Fishery Guidetobe Rich. 3:57–58.
  • Liu WZ. 2020. Using Chinese herbal medicine to treat eel disease. New Countrys. 12:28.
  • Liu XP, Zhang C, Tan ZW, Liu YX, Yu AN. 2009. Study on chemical components for volatile oil from Polygonum flaccidum Messin. Chin J Mod Appl Pharm. 26:285–288.
  • Liu YX, Qin JF, Zhang BB, Tang WY. 2009. Fatty acids from Polygonum hydropiper L. J Henan Univ Med Sci. 28(01):32–34.
  • Lu CX, Huang HC, Tu LQ, Xie J, Ren CZ. 2021. Study on anti-PRV activity ethyl acetate of flavonoid from. Polygonum hydropiper L. in vitro. Heilongjiang J Anim Sci Vet Med. 5:131–135.
  • Luo WJ, Tao JY, Yang J, Zeng Y, Wei YY, Hu TJ. 2017. Effects of flavonoids from Polygonum hydropiper on levels of reactive oxygen species and inflammatory factors in RAW264.7 cells induced by lipopolysaccharide. Prog Vet Med. 38(08):1–6.
  • Luo XY. 2017. Study on quality evaluation and antibacterial activity in vitro of Polygonum hydropiper [master’s thesis]. Guangzhou: Guangdong Pharmaceut Univ. p. 36–38.
  • Luo XY, Cheng XX, Yang HW, Wen ST, Yang Q. 2017. Study on extraction technology of total flavonoids from Polygonum hydropiper and antimicrobial susceptibility of different polarity fractions. Mod Chin Med. 19:839–844.
  • Ma YM, Li MY, Guo LX, Qiao K, Fan C. 2017. Antibacterial and antioxidant activity of the chemical compositions of Polygonum hydropiper L. J Shanxi Univ Sci Technol. 35(01):120–123.
  • Maheswaran R, Ignacimuthu S. 2013. Bioefficacy of essential oil from Polygonum hydropiper L. against mosquitoes, Anopheles stephensi and Culex quinquefasciatus. Ecotoxicol Environ Saf. 97:26–31.
  • Miyazawa M, Tamura N. 2007. Inhibitory compound of tyrosinase activity from the sprout of Polygonum hydropiper L. (Benitade). Biol Pharm Bull. 30(3):595–597.
  • Muhammad A, Muhammad J, Farhat U, Abdul S, Fazal S, Azam KM, Waqar A, Gowhar A, Muhammad I, Sajjad A. 2016. Molecularly characterized solvent extracts and saponins from Polygonum hydropiper L. show high anti-angiogenic, anti-tumor, brine shrimp, and fibroblast NIH/3T3 cell line cytotoxicity. Front Pharmacol. 7:74.
  • Muhammad A, Muhammad J, Jawad A, Farhat U, Abdul S, Imran S. 2014. Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L. BioMed Central. 14:145.
  • Oany AR, Siddikey AA, Hossain MU, Islam R, Emran AA. 2016. A preliminary evaluation of cytotoxicity, antihyperglycemic and antinociceptive activity of Polygonum hydropiper L. ethanolic leaf extract. Clin Phytosci. 2(1):1–6.
  • Ono K, Nakao M, Toyota M, Terashi Y, Yamada M, Kohno T, Asakawa Y. 1998. Catechin production in cultured Polygonum hydropiper cells. Phytochemistry. 49(7):1935–1939.
  • Peng WD. 2016. Characteristics and applications of botanical insecticides. Gansu Sci Technol. 32(19):143–144.
  • Ren CZ, Lu CX, Wei YY, Yu ML, Hu TJ. 2021. Effect of ethyl acetate fraction of flavonoids from Polygonum hydropiper L. on cytokines secretion in RAW264.7 cells induced by Pseudorabies virus. China Anim Husb Vet Med. 48:1132–1140.
  • Ren SZ, Su WQ, Zhu HR, Wang N, Niu HY, Zhao YM, Ma ZJ. 2018. Study on protective effects of Polygonum hydropiper extract on acute gastric mucosal injury in rats. China Pharm. 29:955–958.
  • Ren XD. 2017. Diagnosis and treatment of porcine epidemic diarrhea. Chin J Anim Husb Vet Med. (12):83.
  • Sharif S, Shahriar M, Haque M, Chowdury ZS, Islam M, Bhuiyan MA. 2013. In-vitro antioxidant activities, anti-nociceptive and neuropharmacological activities of Polygonum hydropiper. J Biol Agric Healthc. 19(3):62–70.
  • Shi YW, Liu QZ, Jiang H, Wang HJ, Liu Y. 2017. Extraction processed antibacterial activity on total flavonoids from Polygonum hydropiper. Mod J Anim Husb Vet Med. 4:5–8.
  • Tao JY, Wei YY, Hu TJ. 2016. Flavonoids of Polygonum hydropiper L. attenuates lipopolysaccharide-induced inflammatory injury via suppressing phosphorylation in MAPKs pathways. BMC Complement Altern Med. 16:25.
  • Tripathi AK, Jain DC, Singh SC. 1999. Persistency of bioactive fractions of Indian plant, Polygonum hydropiper as an insect feeding deterrent. Phytother Res. 13(3):239–241.
  • Wang DY, Tang C, Liao BX, Luo J, Pan NS. 2019. Microscopic identification and detection of metallic, elements in Polygonum flaccidum Meissn. in Guizhou. Food Drug. 21(01):24–27.
  • Wang GQ. 2014. National Compendium of Chinese Herbal Medicine (Volume II). Beijing: people’s Health Publishing House. p. 1110–1111. Chinese.
  • Wang HC. 2008. Germplasm resources and prospect of utilization and exploitation about Polygonum L. Qinghai Prataculture. 17(4):17–21.
  • Wang JH, Liu ZT, Zhao XR. 1996. An initial study on chemical composition and tissue of 6 medicinal plants of Polygonum. Henan Sci. 109–111.
  • Wang JX. 2016. Application of Chinese herbal medicine in aquaculture. Shandong J Anim Sci Vet Med. 37(11):56–57. Chinese.
  • Wang PQ, Zhang XN, Liu YX, Li CL, Kang WY. 2013. Antibacterial activities of nine Polygonaceae plants. Chin J Exp Tradit Med Formulae. 19(17):109–112.
  • Wang W, Xia XH, Zeng R, Chen SH, Fu RG, Li B, Xie Q, Hu J, Xie LJ. 2018. Scientific and technological achievements. Chasngsha: Hunan University of Traditional Chinese Medicine. Chinese.
  • Wang XY, Li YM, Sun QX. 2021. How to prevent and cure fish disease with Chinese herbal medicine in high temperature season. J Aquac. 42(9):71–72.
  • Wang Y, Yu TY, Wang ZB, Wang QH, Kuang HX. 2017. GC-MS analysis and antibacterial effect of volatile. oil in Polygonum hydropiper. Chem Eng. 31(12):26–29.
  • Wang YC, Wei K, Lin J. 2012. Recent advances of chemical constituents and pharmacological activities of genus Polygonum. Guangdong Chem Ind. 39(09):16–17.
  • Wang YP, Wang QY, Wang YY. 1996. A review of Chinese medicinal plants of the genus Polygonum. Lishizhen Med Mater Med Res. (03):47–48.
  • Wang ZX. 1996. Newly complied Latin Chinese-English Plant Names. Beijing: Aviation Press. p. 569.
  • Wu LY, Li Q, Cang T. 2007. Study on the extraction technology and insecticidal activities of volatile oil of Polygonum hydropiper Linn. Guangdong Agric Sci. 9:72–73.
  • Xiao H. 2018. Study on the chemical composition of dichloromethane fraction and its active diversity in Polygonum hydropiper [master’s thesis]. Changsha: Hunan University of Traditional Chinese Medicine.
  • Xiao H, Ravu RR, Tekwani BL, Li W, Liu WB, Jacob MR, Khan SI, Ca X, Peng CY, Khan IA, et al. 2017. Biological evaluation of phytoconstituents from Polygonum hydropiper. Nat Prod Res. 31(17):2053–2057.
  • Xiao ZH, Luo XY, Cheng XX, Zheng SJ, Yang Q, Yang HW. 2018. Effect of polygoni hydropiperis herbal on intestinal mucosal repair in diarrhea mice induced by Escherichia coli. Chin J Exp Med Formulae. 24(22):120–126.
  • Xie YH, Li L, Xiao Q, Yu ML, Hu TJ. 2021. Effect of flavonoids from Polygonum perfoliatum L. on immune regulation in mice. Mod J Anim Husb Vet Med. 1:28–32.
  • Xu R, Xiong W, Long ZB, Tang L. 2017. The chemical constituent study of Polygonum hydropiper L. Guangdong Chem Ind. 44(05):22–23.
  • Yagi A, Uemura T, Okamura N, Haraguchi H, Imoto T, Hashimoto K. 1994. Antioxidative sulphated flavonoids in leaves of Polygonum hydropiper. Phytochemistry. 35(4):885–887.
  • Yang XZ, Hao ZY, Zhu YC, Dong Y, Lin HK. 2014. Antioxidant activity of different parts of Polygonum hydropiper. Jiangsu Agric Sci. 42:284–285.
  • Yang YY, Yu T, Jang HJ, Byeon SE, Song SY, Lee BH, Rhee MH, Kim TW, Lee J, Hong S, et al. 2012. In vitro and in vivo anti-inflammatory activities of Polygonum hydropiper methanol extract. J Ethnopharmacol. 139(2):616–625.
  • Yao ZF, Zhou LC, Liu JX. 1999. Study on the chemical composition of volatile oil of Polygonum hydropiper in Hunan. Nat Prod Res Dev. 2:37–40.
  • Yu XL, Luo J, Yang Y, Tang C, Wang DY, Pan NS, Liu YB, Liu L. 2018. Comparison of volatile constituents of Polygonum hydropiper in May, August and November produced in Guizhou China. J Guizhou Med Coll. 43(02):144–153.
  • Yue L. 2020. Effects of Polygonum hydropiper on the expressions levels of inflammatory cytokines and cytochrome P450 enzymes in the diarrhea mice induced by E. coli. [master’s thesis]. Guangzhou: Guangdong Pharmaceutical University. p. 54–70.
  • Zeng WA. 2007. Study on insecticidal constituents of Polygonum hydropiper Linn. [dissertation]. Changsha: Hunan Agricultural University.
  • Zeng WA, Tan JC, Tan L, Chen JZ. 2007. Biological activities of crude extracts from Polygonum hydropiper L. against Pieris rapae L. J Hunan Agric Univ. 33(01):76–78.
  • Zeng WA, Tan JC, Tan L, Zhang CY, Chen JZ, Li XW, Li M. 2006. Application and efficacy of Polygonum hydropiper L. Chin Agric Sci Bull. 8:369–372.
  • Zhang GY. 2004. Extraction, isolation, and identification of major components [master’s thesis]. Nanjing: Nanjing Forestry University.
  • Zhang GY, Zeng T. 2005. Study on chemical constituents of Polygonum hydropiper Linn. Chem Ind for Prod. 25(03):21–24.
  • Zhang HQ. 2014. Fresh Polygonum hydropiper L. to treat livestock mange. Chin J Tradit Vet Sci. (5):74.
  • Zhang S, Guo Y, Zhao QH, Xue WH, Li YR, Wu XJ, Huo SY. 2020. Study on the bacteriostatic action of Chinese herbal medicine on avian Trichosporon. Poult Sci. 99(9):4530–4538.
  • Zhang S, Zhao QH, Xue WH, Li YR, Guo Y, Wu XJ, Huo SY, Li Y, Li CY. 2021. The isolation and identification of Candida glabrata from avian species and a study of the antibacterial activities of Chinese herbal medicine in vitro. Poult Sci. 100(4):1–10.
  • Zhang W, Pan YN, Qu SH, Wang DM, Cheng S, Liu XQ. 2018. Anti-inflammatory effects of an extract of Polygonum hydropiper stalks on 2,4,6-trinitrobenzenesulphonic acid-induced intestinal inflammation in rats by inhibiting the NF-κB pathway. Mediators Inflamm. 2018:6029135.
  • Zhang W, Tan ZB, Cheng J, Yu ML, Wei YY, Li J, Hu TJ. 2022. Study on acute and subchronic toxicity of Polygonum hydropiper L. extract. China Anim Husb Med. 49(4):1532–1544.
  • Zhao FP, Strack D, Baumert A, Subramaniam R, Goh NK, Chia TF, Tan SN, Chia LS. 2003. Antioxidant flavonoids from leaves of Polygonum hydropiper L. Phytochemistry. 62(2):219–228.
  • Zhou SM, Cao MX, Hu TJ. 2020. Study on effect of anti-PRRSV of n-butanol part of flavonoids from Polygonum. hydropiper L. in vitro. China Anim Husb Vet Med. 47(02):605–611.
  • Zhou SM, Du ZJ. 2019. The preparation of 30 kinds of botanical liquid medicine and the control method of insect pests. Plant Dr. 32(4):37–47.
  • Zhu JG, Li L, Wei YY, Yu ML, Chen LX, Hu TJ. 2020. Preliminary study on toxicology of total flavonoids from Polygonum hydropiper L. Mod J Anim Husb Vet Med. (10):19–23.
  • Zhu YD. 2020. Chemical characterization and immunomodulatory activity of Polygonum odoratum polysaccharides [master’s thesis]. Kunming: Kunming Medical University. p. 10–17.