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Research Article

Punicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway

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Pages 963-972 | Received 28 Sep 2022, Accepted 07 Jun 2023, Published online: 25 Jun 2023

References

  • Abdullaha M, Ali M, Kour D, Kumar A, Bharate SB. 2020. Discovery of benzo[cd]indol-2-one and benzylidene-thiazolidine-2,4-dione as new classes of NLRP3 inflammasome inhibitors via ER-β structure based virtual screening. Bioorg Chem. 95:103500. doi: 10.1016/j.bioorg.2019.103500.
  • An X, Zhang Y, Cao Y, Chen J, Qin H, Yang L. 2020. Punicalagin protects diabetic nephropathy by inhibiting pyroptosis based on TXNIP/NLRP3 pathway. Nutrients. 12(5):1516–1527. doi: 10.3390/nu12051516.
  • Buckley LF, Libby P. 2019. Inhibiting NLRP3 inflammasome activity in acute myocardial infarction: a review of pharmacologic agents and clinical outcomes. J Cardiovasc Pharmacol. 74(4):297–305. doi: 10.1097/FJC.0000000000000701.
  • Chen P, Pei J, Wang X, Tai S, Tang L, Hu X. 2022. Gut bacterial metabolite urolithin A inhibits myocardial fibrosis through activation of Nrf2 pathway in vitro and in vivo. Mol Med. 28(1):19. doi: 10.1186/s10020-022-00444-1.
  • Ding M, Wang Y, Sun D, Liu Z, Wang J, Li X, Huo C, Jia X, Chen W, Fu F, et al. 2017. Punicalagin pretreatment attenuates myocardial ischemia-reperfusion injury via activation of AMPK. Am J Chin Med. 45(1):53–66. doi: 10.1142/S0192415X17500057.
  • Fang L, Wang H, Zhang J, Fang X. 2021. Punicalagin induces ROS-mediated apoptotic cell death through inhibiting STAT3 translocation in lung cancer A549 cells. J Biochem Mol Toxicol. 35(6):1–10. doi: 10.1002/jbt.22771.
  • Fu F, Liu C, Shi R, Li M, Zhang M, Du Y, Wang Q, Li J, Wang G, Pei J, et al. 2021. Punicalagin protects against diabetic cardiomyopathy by promoting opa1-mediated mitochondrial fusion via regulating PTP1B-Stat3 pathway. Antioxid Redox Signal. 35(8):618–641. doi: 10.1089/ars.2020.8248.
  • Ge G, Bai J, Wang Q, Liang X, Tao H, Chen H, Wei M, Niu J, Yang H, Xu Y, et al. 2022. Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway. Sci China Life Sci. 65(3):588–603. doi: 10.1007/s11427-020-1939-1.
  • He Y, Pang S, Huang J, Zhu K, Tong J, Tang Y, Ma G, Chen L. 2018. Blockade of RBP-J-mediated notch signaling pathway exacerbates cardiac remodeling after infarction by increasing apoptosis in mice. Biomed Res Int. 2018:5207031. doi: 10.1155/2018/5207031.
  • Hering NA, Luettig J, Jebautzke B, Schulzke JD, Rosenthal R. 2021. The punicalagin metabolites ellagic acid and urolithin A exert different strengthening and anti-inflammatory effects on tight junction-mediated intestinal barrier function in vitro. Front Pharmacol. 12:610164. doi: 10.3389/fphar.2021.610164.
  • Hua Q, Han Y, Zhao H, Zhang H, Yan B, Pei S, He X, Li Y, Meng X, Chen L, et al. 2022. Punicalagin alleviates renal injury via the gut-kidney axis in high-fat diet-induced diabetic mice. Food Funct. 13(2):867–879. doi: 10.1039/d1fo03343c.
  • Hua F, Shi L, Zhou P. 2022. Phenols and terpenoids: natural products as inhibitors of NLRP3 inflammasome in cardiovascular diseases. Inflammopharmacology. 30(1):137–147. doi: 10.1007/s10787-021-00918-4.
  • Kuang S, Zheng J, Yang H, Li S, Duan S, Shen Y, Ji C, Gan J, Xu XW, Li J. 2017. Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis. Proc Natl Acad Sci USA. 114(40):10642–10647. doi: 10.1073/pnas.1708194114.
  • Lei Q, Yi T, Chen C. 2018. NF-κB-Gasdermin D (GSDMD) axis couples oxidative stress and NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome-mediated cardiomyocyte pyroptosis following myocardial infarction. Med Sci Monit. 24:6044–6052. doi: 10.12659/MSM.908529.
  • Lim SH, Kim Y, Yun KN, Kim JY, Jang J-H, Han M-J, Lee J. 2016. Plant-based foods containing cell wall polysaccharides rich in specific active monosaccharides protect against myocardial injury in rat myocardial infarction models. Sci Rep. 6:38728. doi: 10.1038/srep38728.
  • Liu Y, Grimm M, Dai WT, Hou MC, Xiao ZX, Cao Y. 2020. CB-Dock: a web server for cavity detection-guided protein-ligand blind docking. Acta Pharmacol Sin. 41(1):138–144. doi: 10.1038/s41401-019-0228-6.
  • Liu Y, Kong KW, Wu DT, Liu HY, Li HB, Zhang JR, Gan RY. 2022. Pomegranate peel-derived punicalagin: ultrasonic-assisted extraction, purification, and its α-glucosidase inhibitory mechanism. Food Chem. 374:131635. doi: 10.1016/j.foodchem.2021.131635.
  • Mezzaroma E, Abbate A, Toldo S. 2021. NLRP3 inflammasome inhibitors in cardiovascular diseases. Molecules. 26(4):976. doi: 10.3390/molecules26040976.
  • Patel RB, Ter Maaten JM, Ferreira JP, McCausland FR, Shah SJ, Rossignol P, Solomon SD, Vaduganathan M, Packer M, Thompson A, et al. 2021. Challenges of cardio-kidney composite outcomes in large-scale clinical trials. Circulation. 143(9):949–958. doi: 10.1161/CIRCULATIONAHA.120.049514.
  • Seo Y, Mun CH, Park SH, Jeon D, Kim SJ, Yoon T, Ko E, Jo S, Park YB, Namkung W, et al. 2020. Punicalagin ameliorates lupus nephritis via inhibition of PAR2. IJMS. 21(14):4975. doi: 10.3390/ijms21144975.
  • Shen J, Fan Z, Sun G, Qi G. 2021. Sacubitril/valsartan (LCZ696) reduces myocardial injury following myocardial infarction by inhibiting NLRP3-induced pyroptosis via the TAK1/JNK signaling pathway. Mol Med Rep. 24(3):676. doi: 10.3892/mmr.2021.12315.
  • Shen S, Wang Z, Sun H, Ma L. 2022. NLRP3 inflammasome in myocardial ischemia-reperfusion injury and ventricular remodeling. Med Sci Monit. 28:e934255. doi: 10.12659/MSM.934255.
  • Silvis MJM, Demkes EJ, Fiolet ATL, Dekker M, Bosch L, van Hout GPJ, Timmers L, de Kleijn DPV. 2021. Immunomodulation of the NLRP3 inflammasome in atherosclerosis, coronary artery disease, and acute myocardial infarction. J Cardiovasc Transl Res. 14(1):23–34. doi: 10.1007/s12265-020-10049-w.
  • Sokolova M, Sjaastad I, Louwe MC, Alfsnes K, Aronsen JM, Zhang L, Haugstad SB, Bendiksen BA, Øgaard J, Bliksøen M, et al. 2019. NLRP3 inflammasome promotes myocardial remodeling during diet-induced obesity. Front Immunol. 10:1621. doi: 10.3389/fimmu.2019.01621.
  • Subkorn P, Norkaew C, Deesrisak K, Tanyong D. 2021. Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia. PeerJ. 9:e12303. doi: 10.7717/peerj.12303.
  • Suetomi T, Willeford A, Brand CS, Cho Y, Ross RS, Miyamoto S, Brown JH. 2018. Inflammation and NLRP3 inflammasome activation initiated in response to pressure overload by Ca2+/Calmodulin-dependent protein kinase II δ signaling in cardiomyocytes are essential for adverse cardiac remodeling. Circulation. 138(22):2530–2544. doi: 10.1161/CIRCULATIONAHA.118.034621.
  • Venusova E, Kolesarova A, Horky P, Slama P. 2021. Physiological and immune functions of punicalagin. Nutrients. 13(7):2150. doi: 10.3390/nu13072150.
  • Wang L, Shi H, Huang JL, Xu S, Liu PP. 2020. Linggui Zhugan decoction inhibits ventricular remodeling after acute myocardial infarction in mice by suppressing TGF-β1/Smad signaling pathway. Chin J Integr Med. 26(5):345–352. doi: 10.1007/s11655-018-3024-0.
  • Xie X, Hu L, Liu L, Wang J, Liu Y, Ma L, Sun G, Li C, Aisa HA, Meng S. 2022. Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway. Transl Oncol. 19:101388. doi: 10.1016/j.tranon.2022.101388.
  • Xu J, Cao K, Liu X, Zhao L, Feng Z, Liu J. 2021. Punicalagin regulates signaling pathways in inflammation-associated chronic diseases. Antioxidants. 11(1):29. doi: 10.3390/antiox11010029.
  • Xu P, Xu L, Huang S, Li D, Liu Y, Guo H, Dai N, Hong Z, Zhong S. 2022. Analysis of the molecular mechanism of punicalagin in the treatment of Alzheimer’s disease by computer-aided drug research technology. ACS Omega. 7(7):6121–6132. doi: 10.1021/acsomega.1c06565.
  • Yan Z, Qi Z, Yang X, Ji N, Wang Y, Shi Q, Li M, Zhang J, Zhu Y. 2021. The NLRP3 inflammasome: multiple activation pathways and its role in primary cells during ventricular remodeling. J Cell Physiol. 236(8):5547–5563. doi: 10.1002/jcp.30285.
  • Ye M, Zhang L, Yan Y, Lin H. 2019. Punicalagin protects H9c2 cardiomyocytes from doxorubicin-induced toxicity through activation of Nrf2/HO-1 signaling. Biosci Rep. 39: BSR20190229.
  • Yu LM, Dong X, Xue XD, Zhang J, Li Z, Wu HJ, Yang ZL, Yang Y, Wang HS. 2019. Protection of the myocardium against ischemia/reperfusion injury by punicalagin through an SIRT1-NRF-2-HO-1-dependent mechanism. Chem Biol Interact. 306:152–162. doi: 10.1016/j.cbi.2019.05.003.
  • Yu L, Li J. 2022. Punicalagin alleviates aged bronchial asthma by inhibiting Th2 differentiation through IL-4/STAT6 and Jagged1/Notch pathways. J Healthc Eng. 2022:1184677. doi: 10.1155/2022/1184677.
  • Zhang Y, Aisker G, Dong H, Halemahebai G, Zhang Y, Tian L. 2021. Urolithin A suppresses glucolipotoxicity-induced ER stress and TXNIP/NLRP3/IL-1β inflammation signal in pancreatic β cells by regulating AMPK and autophagy. Phytomedicine. 93:153741. doi: 10.1016/j.phymed.2021.153741.
  • Zhang C, Song Y, Chen L, Chen P, Yuan M, Meng Y, Wang Q, Zheng G, Qiu Z. 2022. Urolithin A attenuates hyperuricemic nephropathy in fructose-fed mice by impairing STING-NLRP3 axis-mediated inflammatory response via restoration of Parkin-dependent mitophagy. Front Pharmacol. 13:907209. doi: 10.3389/fphar.2022.907209.
  • Zhou P, Zhao CC, Li JY, Zhang M, Shi H, Wang L. 2022. A review on the role of quinines in cardiovascular disease via inhibiting NLRP3 inflammasome. Acta Pol Pharm. 78(6):743–748. doi: 10.32383/appdr/146288.