Physical activity and health: Metabolic and cardiovascular issues

References

• The World Health Report 2002. Reducing risks, promoting healthy life. Geneva: World Health Organization; 2002.
   Google Scholar
• International Agency for Research of Cancer Prevention. In: Vainio H, Bianchini Fr. Weight control and physical activity. IARC handbooks of cancer prevention, volume 6. Lyon: IARC Press; 2002.
   Google Scholar
• Colditz GA. Economic costs of obesity and inactivity. Med Sci Sports Exerc. 1999; 31 Suppl: 663–7
   Google Scholar
• Smith SC. Multiple risk factors for cardiovascular disease and diabetes mellitus. Am J Med. 2007; 120(3 Suppl 1)S3–11
   PubMed Web of Science ®Google Scholar
• Daniels SR, Arnett DK, Eckel RH, Gidding SS, Hayman LL, Kumanyika S, et al. Overweight in children and adolescents. American Heart Association Scientific Statement. Circulation 2005; 111: 1999–2012
   PubMed Web of Science ®Google Scholar
• Despres JP, Lemieux I. Abdominal obesity and metabolic syndrome. Nature. 2006; 444: 881–7
   PubMed Web of Science ®Google Scholar
• Ford ES, Abbasi F, Reaven GM. Prevalence of insulin resistance and the metabolic syndrome with alternative definitions of impaired glucose tolerance. Atherosclerosis. 2005; 181: 143–8
   PubMed Web of Science ®Google Scholar
• Assmann G, Guerra R, Fox G, Cullen P, Schulte H, Willett D, Grundy SM. Harmonizing the definition of the metabolic syndrome: Comparison of the criteria of the Adult Treatment Panel III and the International Diabetes Federation in the United States American and European populations. Am J Cardiol. 2007; 99: 541–8
   PubMed Web of Science ®Google Scholar
• Park YW, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB. The metabolic syndrome: Prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1998–1994. Arch Intern Med. 2003; 163: 427–36
   PubMed Web of Science ®Google Scholar
• Liu S, Manson JE. Dietary carbohydrates, physical inactivity, obesity, and the ‘metabolic syndrome’ as predictors of coronary heart disease. Curr Opin Lipidol. 2002; 12: 395–404
   Web of Science ®Google Scholar
• Alexander CM, Landsman PB, Teutsch SM, Haffner SM; Third National Health and Nutrition Examination Survey (NHANES III); National Cholesterol Education Program (NCEP). NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older. Diabetes. 2003;52:1210–4.
   PubMed Web of Science ®Google Scholar
• Ninomiya JK, L'Italien G, Criqui MH, Whyte JL, Gamst A, Chen RS. Association of the metabolic syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey. Circulation. 2003; 109: 42–46
   PubMed Web of Science ®Google Scholar
• McNeill AM, Katz R, Girman CJ, Rosamond WD, Wagenknecht LE, Barzilay JI, et al. Metabolic syndrome and cardiovascular disease in older people: The cardiovascular health study. J Am Geriatr Soc. 2006; 545: 1317–24
   Google Scholar
• World Health Organization–International Society of Hypertension guidelines for the management of hypertension. J Hypertension. 1999;17:151–183.
   PubMed Web of Science ®Google Scholar
• Tegos TJ, Kalodiki E, Daskalopoulou SS, Nicolaides AN. Stroke: Epidemiology, clinical picture, and risk factors. Angiology. 2000; 51: 793–808
   PubMed Web of Science ®Google Scholar
• De Freitas GR, Bogousslavsky J. Primary stroke prevention. Eur J Neurology. 2001; 8: 1–15
   PubMed Web of Science ®Google Scholar
• Stewart KJ, Hiatt WR, Regensteiner JG, Hirsch AT. Exercise training for claudication. N Engl J Med. 2002; 347: 1941–51
   PubMed Web of Science ®Google Scholar
• Puska P, Tuomilehto J, Nissinen A, Vartiainen E. The North Karelia Project. Helsinki: The National Public Health Institute, KTL; 1995.
   Google Scholar
• de Almeida MDV. Population levels and patterns of physical activity for health. Health-enhancing physical activity, P Oja, J Borms. Meyer & Meyer Sport, Oxford 2004; 271–93
   Google Scholar
• Mathers CD, Vos ET, Stevenson CE, Begg SJ. The Australian Burden of Disease Study: Measuring the loss of health from diseases, injuries and risk factors. MJA. 2000; 172: 592–6
   PubMed Web of Science ®Google Scholar
• Mathers CD, Vos ET, Stevenson CE, Begg SJ. The burden of disease and injury in Australia. Bull World Health Organ. 2001; 79: 1076–84
   PubMed Web of Science ®Google Scholar
• Katzmarzyk PT, Gledhill N, Shephard RJ. The economic burden of physical inactivity in Canada. CMAJ. 2000; 163: 1435–40
   PubMed Web of Science ®Google Scholar
• Bronnum-Hansen H. Predicting the effect of prevention of ischaemic heart disease. Scand J Public Health. 2002; 30: 5–11
   PubMed Web of Science ®Google Scholar
• Single E, Robson L, Xie X, Rehm J. The economic costs of alcohol, tobacco and illicit drugs in Canada, 1992. Addiction. 1998; 93: 991–1006
   PubMed Web of Science ®Google Scholar
• Birmingham CL, Muller JL, Palepu A, Spinelli JJ, Anis AH. The cost of obesity in Canada. CMAJ. 1999; 160: 483–8
   PubMed Web of Science ®Google Scholar
• Katzmarzyk PT, Janssen I. The economic costs associated with physical inactivity and obesity in Canada: An update. CMAJ. 2004; 29: 90–115
   Google Scholar
• Pronk NP, Goodman MJ, O'Connor PJ, Martinson BC. Relationship between modifiable health risks and short-term health care charges. JAMA. 1999; 282: 2235–9
   PubMed Web of Science ®Google Scholar
• Anderson LH, Martinson BC, Crain AL, Pronk NP, Whitebird RR, O'Connor PJ, et al. Health care charges associated with physical inactivity, overweight, and obesity. Prev Chronic Dis. 2005; 2: 1–12
   Google Scholar
• Ravussin E, Swinburn BA. Metabolic predictors of obesity: Cross-sectional versus longitudinal data. Int J Obes. 1993; 17(Suppl 3)S28–31
   Google Scholar
• Feskanich D, Willett W, Colditz G. Walking and leisure-time activity and risk of hip fracture in postmenopausal women. JAMA. 2002; 288: 2300–6
   PubMed Web of Science ®Google Scholar
• Hu FB, Li TY, Colditz GA, Willett WC, Manson JE. Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA. 2003; 289: 1785–91
   PubMed Web of Science ®Google Scholar
• Holcomb CA, Heim DL, Loughin TM. Physical activity minimizes the association of body fatness with abdominal obesity in white, premenopausal women: Results from the Third National Health and Nutrition Examination Survey. J Am Diet Assoc. 2004; 104: 1859–62
   PubMed Web of Science ®Google Scholar
• Fogelholm M, Kukkonen-Harjula K. Does physical activity prevent weight gain – A systematic review. Obesity Rev. 2000; 1: 95–111
   PubMedGoogle Scholar
• Petrella RJ, Lattanzio CN, Demeray A, Varallo V, Blore R. Can adoption of regular exercise later in life prevent metabolic risk for cardiovascular disease?. Diabetes Care. 2005; 28: 694–701
   PubMed Web of Science ®Google Scholar
• Rosell M, Appleby P, Spencer E, Key T. Weight gain over 5 years in 21 966 meat-eating, fish-eating, vegetarian, and vegan men and women in EPIC-Oxford. Int J Obes. 2006; 30: 1389–96
   PubMed Web of Science ®Google Scholar
• Bak H, Petersen L, Sörensen TIA. Physical activity in relation to development and maintenance of obesity in men with and without juvenile onset obesity. Int J Obes. 2004; 28: 99–104
   Web of Science ®Google Scholar
• Petersen L, Schnor P, Sörensen TIA. Longitudinal study of the long-term relation between physical activity and obesity in adults. Int J Obes. 2004; 28: 105–12
   Web of Science ®Google Scholar
• Dunn AL, Marcus BH, Kampert JB, Garcia ME, Kohl HW, Brasel JA. Comparison of lifestyle and structured interventions to increase physical activity and cardiorespiratory fitness. JAMA. 1999; 281: 327–34
   PubMed Web of Science ®Google Scholar
• Donnelly JE, Jacobsen DJ, Snyder Heelan KA, Seip R, Smith S. The effects of 18 months of intermittent vs continuous exercise on aerobic capacity, body weight and composition, and metabolic fitness in previously sedentary, moderately obese females. Int J Obes. 2000; 24: 566–72
   PubMed Web of Science ®Google Scholar
• Slentz CA, Aiken LB, Houmard JA, Bales CW, Johnson JL, Tanner CJ, et al. Inactivity, exercise, and visceral fat. STRRIDE: A randomized, controlled study of exercise intensity and amount. J Appl Physiol. 2005; 99: 1613–8
   PubMed Web of Science ®Google Scholar
• Saris WH, Blair SN, van Baak MA, Eaton SB, Davies PS, Di Pietro L, et al. How much physical activity is enough to prevent unhealthy weight gain? Outcome of the IASO 1st Stock Conference and consensus statement. Obes Rev. 2003; 4: 101–4
   PubMedGoogle Scholar
• Wareham NJ, van Sluijs EM, Ekelund U. Physical activity and obesity prevention: A review of the current evidence. Proc Nutr Soc. 2005; 64: 229–47
   PubMed Web of Science ®Google Scholar
• Jakicic JM, Otto AD. Treatment and prevention of obesity: What is the role of exercise?. Nutr Rev. 2006; 64: S57–61
   PubMed Web of Science ®Google Scholar
• Avenell A, Broom J, Brown TJ, Poobalan A, Aucott L, Stearns SC, et al. Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement. Health Technol Assess. 2004;8: iii-iv, 1–182.
   Web of Science ®Google Scholar
• Ross R, Dagnone D, Jones PJ, Smith H, Paddags A, Hudson R, Janssen I. Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. A randomized, controlled trial. Ann Intern Med. 2000; 133: 92–103
   PubMed Web of Science ®Google Scholar
• Ross R, Janssen I, Dawson J, Kungl AM, Kuk JL, Wong SL, et al. Exercise-induced reduction in obesity and insulin resistance in women: A randomized controlled trial. Obes Res. 2004; 12: 789–98
   PubMedGoogle Scholar
• Donnelly JE, Hill JO, Jacobsen DJ, Potteiger J, Sullivan DK, Johnson SL, et al. Effects of a 16-month randomized controlled exercise trial on body weight and composition in young, overweight men and women: The Midwest Exercise Trial (MET). Arch Intern Med. 2003; 163: 1343–50
   PubMed Web of Science ®Google Scholar
• Jakicic JM, Winters C, Lang W, Wing RR. Effects of intermittent exercise and use of home exercise equipment on adherence, weight loss, and fitness in overweight women. JAMA. 1999; 282: 1554–60
   PubMed Web of Science ®Google Scholar
• Borg P, Kukkonen-Harjula K, Fogelholm M, Pasanen M. Effects of walking or resistance training on weight loss maintenance in obese, middle-aged men: A randomized trial. Int J Obes. 2002; 26: 676–83
   PubMed Web of Science ®Google Scholar
• LeCheminant JD, Jacobsen DJ, Hall MA, Donnelly JE. A comparison of meal replacements and medication in weight maintenance after weight loss. Am J Clin Nutr. 2005; 24: 347–53
   Web of Science ®Google Scholar
• Bjorntorp P, De Jounge K, Sjostrom L, Sullivan L. The effect of physical training on insulin production in obesity. Metabolism. 1970; 19: 631–8
   PubMed Web of Science ®Google Scholar
• Lamarche B, Despres JP, Pouliot MC, Moorjani S, Lupien PJ, Theriault G, et al. Is body fat loss a determinant factor in the improvement of carbohydrate and lipid metabolism following aerobic exercise training in obese women?. Metabolism. 1992; 41: 1249–56
   PubMed Web of Science ®Google Scholar
• Lynch NA, Nicklas BJ, Berman DM, Dennis KE, Goldberg AP. Reductions in visceral fat during weight loss and walking are associated with improvements in VO2max. J Appl Physiol. 2001; 90: 99–104
   PubMed Web of Science ®Google Scholar
• Miyatake N, Takahashi K, Wada J, Nishikawa H, Morishita A, Suzuki H, et al. Daily exercise lowers blood pressure and reduces visceral adipose tissue areas in overweight Japanese men. Diabetes Res Clin Pract. 2003; 62: 149–57
   PubMed Web of Science ®Google Scholar
• Garrow JS, Summerbell CD. Meta-analysis: Effect of exercise, with or without dieting, on the body composition of overweight subjects. Eur J Clin Nutr. 1995; 49: 110
   Google Scholar
• Willey KA, Fiatarone Singh MA. Battling insulin resistance in elderly obese people with type 2 diabetes. Diabetes Care. 2003; 26: 1580–88
   PubMed Web of Science ®Google Scholar
• Ibanez J, Izquierdo M, Arguelles I, Forga L, Larrion JL, Garcia-Unciti M, et al. Twice-weekly progressive resistance training decreases abdominal fat and improves insulin sensitivity in older men with type 2 diabetes. Diabetes Care. 2005; 28: 662–7
   PubMed Web of Science ®Google Scholar
• Grundy SM, Blackburn G, Higgins M, Lauer R, Perri MG, Ryan D. Physical activity in the prevention and treatment of obesity and its comorbidities: Evidence report of independent panel to assess the role of physical activity in the treatment of obesity and its comorbidities. Med Sci Sports Exerc. 1999; 31 Suppl: S502–8
   Web of Science ®Google Scholar
• Blair SN, Church TS. The fitness, obesity, and health equation. Is physical activity the common nominator?. JAMA. 2004; 292: 1232–4
   PubMed Web of Science ®Google Scholar
• Blair SN, Brodney S. Effects of physical inactivity and obesity on morbidity and mortality: Current evidence and research issues. Med Sci Sports Exerc. 1999; 31 Suppl: S646–62
   Web of Science ®Google Scholar
• Olefsky JM. Prospects for research in diabetes mellitus. JAMA. 2001; 285: 623–32
   Google Scholar
• Albright A, Franz M, Hornsby G, Kriska A, Marrero D, Ullrich I, et al. American College of Sports Medicine position stand. Exercise and type 2 diabetes. Med Sci Sports Exerc. 2000;32:1345–60. Available at: http//www.msse.org.
   PubMed Web of Science ®Google Scholar
• Vuori IM. Health benefits of physical activity with special reference to interaction with diet. (A review). Public Health Nutr. 2001; 4: 517–28
   PubMedGoogle Scholar
• Helmrich SP, Ragland DR, Leung RW, Paffenbarger RS, Jr. Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus. N Engl J Med. 1991; 325: 147–52
   PubMed Web of Science ®Google Scholar
• Manson JE, Rimm EB, Stampfer MJ, Colditz GA, Willett WC, Krolewski AS, et al. Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. Lancet. 1991; 338: 774–8
   PubMed Web of Science ®Google Scholar
• Haapanen N, Miilunpalo S, Vuori I, Oja P, Pasanen M. Association of leisure time physical activity with the risk of coronary heart disease, hypertension and diabetes in middle-aged men and women. Int J Epidemiol. 1997; 26: 739–47
   PubMed Web of Science ®Google Scholar
• Folsom AR, Kushi LH, Hong CP. Physical activity and incident diabetes mellitus in postmenopausal women. Am J Public Health. 2000; 90: 134–8
   PubMed Web of Science ®Google Scholar
• Wannamethee SG, Shaper G, Alberti GMM. Physical activity, metabolic factors, and the incidence of coronary heart disease and type 2 diabetes. Arch Intern Med. 2000; 160: 2108–16
   PubMed Web of Science ®Google Scholar
• Hsia J, Wu L, Allen C, Oberman A, Lawson WE, Torrens J, et al. Physical activity and diabetes risk in postmenopausal women. Am J Prev Med. 2005; 28: 19–25
   PubMed Web of Science ®Google Scholar
• Lynch J, Helmrich SP, Lakka TA, Kaplan GA, Cohen RD, Salonen R, et al. Moderately intense physical activities and high levels of cardiorespiratory fitness reduce the risk of non-insulin-dependent diabetes mellitus in middle-aged men. Arch Intern Med. 1996; 156: 1307–14
   PubMed Web of Science ®Google Scholar
• Wei M, Gibbons LW, Mitchell TL, Kampert JB, Lee CD, Blair SN. The association between cardiorespiratory fitness and impaired fasting glucose and type 2 diabetes mellitus in men. Ann Intern Med. 1999; 130: 89–96
   PubMed Web of Science ®Google Scholar
• Kelley DE, Goodpaster BH. The effects of exercise on glucose homeostasis in type 2 diabetes mellitus. Med Sci Sports Exerc. 2001; 33 Suppl: 495–501
   Google Scholar
• Hu FB, Sigal RJ, Rich-Edwards JW, Colditz GA, Solomon CG, Willett WC, et al. Walking compared with vigorous physical activity and risk of type 2 diabetes in women: A prospective study. JAMA. 1999; 282: 1433–9
   PubMed Web of Science ®Google Scholar
• Pan XR, Li GW, Hu YH, Wang JX, Yang WY, An ZX, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. Diabetes Care. 1997; 20: 537–44
   PubMed Web of Science ®Google Scholar
• Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001; 344: 1343–50
   PubMed Web of Science ®Google Scholar
• Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002; 346: 393–403
   PubMed Web of Science ®Google Scholar
• Kosaka K, Noda M, Kuzuya T. Prevention of type 2 diabetes by lifestyle intervention: A Japanese trial in IGT males. Diabetes Res Clin Pract. 2005; 67: 152–62
   PubMed Web of Science ®Google Scholar
• Ramachandran A, Snehalatha C, Mary S, Mukesh B, Bhaskar AD, Vijay V. The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP–1). Diabetologia. 2006; 49: 289–97
   PubMed Web of Science ®Google Scholar
• Hamman RF, Wing RR, Edelstein SL, Lachin JM, Bray GA, Delahanty L, et al. Effect of weight loss with lifestyle intervention on risk of diabetes. Diabetes Prevention Program (DPP). Diabetes Care. 2006; 29(9)2102–7
   PubMed Web of Science ®Google Scholar
• Lamonte MJ, Blair SN, Church TS. Physical activity and diabetes prevention. J Appl Physiol. 2005; 99: 1205–13
   PubMed Web of Science ®Google Scholar
• Houmard JA, Tanner CJ, Slentz CA, Duscha BD, McCartney JS, Kraus WE. Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol. 2004; 96: 101–6
   PubMed Web of Science ®Google Scholar
• DiPietro L, Dziura J, Yeckel CW, Neufer PD. Exercise and improved insulin sensitivity in older women: Evidence of the enduring benefits of higher intensity training. J Appl Physiol. 2006; 100: 142–9
   PubMed Web of Science ®Google Scholar
• Eriksson JG. Exercise and the treatment of type 2 diabetes mellitus. Sports Med. 1999; 27: 381–91
   PubMed Web of Science ®Google Scholar
• Castaneda C, Layne JE, Munoz-Orians L, Gordon PL, Walsmith J, Foldvari M, et al. High-intensity progressive resistance exercise training in Hispanic older adults with type 2 diabetes: A randomized controlled trial. Diabetes Care. 2002; 25: 2335–41
   PubMed Web of Science ®Google Scholar
• Dunstan DW, Daly RM, Owen N, Jolley D, De Courten M, Shaw J, et al. High-intensity resistance training improves glycemic control in older patients with type 2 diabetes. Diabetes Care. 2002; 25: 1729–36
   PubMed Web of Science ®Google Scholar
• Wallberg-Henriksson H, Rincon J, Zierath JR. Exercise in the management of non-insulin-dependent diabetes mellitus. Sports Med. 1998; 25: 25–35
   PubMed Web of Science ®Google Scholar
• Wei M, Kampert JB, Barlow CE, Nichaman MZ, Gibbons LW, Paffenbarger RS, Jr, et al. Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men. JAMA. 1999; 282: 1547–53
   PubMed Web of Science ®Google Scholar
• Hu FB, Manson JE, Stampfer MJ, Colditz G, Liu S, Solomon CG, et al. Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med. 2001; 345: 790–7
   PubMed Web of Science ®Google Scholar
• Hu FB, Stampfer MJ, Solomon C, Liu S, Colditz GA, Speizer FE, et al. Physical activity and risk for cardiovascular events in diabetic women. Ann Intern Med. 2001; 134: 96–105
   PubMed Web of Science ®Google Scholar
• Gregg EW, Gerzoff RB, Caspersen CJ, Williamson DF, Narayan KM. Relationship of walking to mortality among US adults with diabetes. Arch Intern Med. 2003; 163: 1440–7
   PubMed Web of Science ®Google Scholar
• Tanasescu M, Leitzmann MF, Rimm EB, Hu FB. Physical activity in relation to cardiovascular disease and total mortality among men with type 2 diabetes. Circulation. 2003; 107: 2435–9
   PubMed Web of Science ®Google Scholar
• Stewart KJ. Exercise training and the cardiovascular consequences of type 2 diabetes and hypertension: Plausible mechanisms for improving cardiovascular health. JAMA. 2002; 288: 622–31
   PubMedGoogle Scholar
• Church TS, LaMonte MJ, Barlow CE, Blair SN. Cardiorespiratory fitness and body mass index as predictors of cardiovascular disease mortality among men with diabetes. Arch Intern Med. 2005; 165: 2114–20
   PubMed Web of Science ®Google Scholar
• Hu G, Eriksson J, Barengo NC, Lakka TA, Valle TT, Nissinen A, et al. Occupational, commuting, and leisure-time physical activity in relation to total and cardiovascular mortality among Finnish subjects with type 2 diabetes. Circulation. 2004; 110: 666–73
   PubMed Web of Science ®Google Scholar
• US Department of Health and Human Services. Physical Activity and Health: A Report of the Surgeon General. Office of the Surgeon General, Atlanta, GA: Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion; 1996. Available at: http://www.cdc.gov/nccdphp/sgr/pdf/sgrfull.pdf.
   Google Scholar
• Reilly MP, Rader DJ. The metabolic syndrome. More than the sum of its parts. Circulation. 2003; 108: 1546–51
   PubMed Web of Science ®Google Scholar
• Finley CE, LaMonte MJ, Waslien CI, Barlow CE, Blair SN, Nichaman MZ. Cardiorespiratory fitness, macronutrient intake, and the metabolic syndrome; The Aerobics Center Longitudinal Study. J Am Diet Assoc. 2006; 106: 673–9
   PubMed Web of Science ®Google Scholar
• Laaksonen DE, Lakka HM, Salonen JT, Niskanen LK, Rauramaa R, Lakka TA. Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome. Diabetes Care. 2002; 25: 1612–18
   PubMed Web of Science ®Google Scholar
• Bertrais S, Beyeme-Ondoua JP, Czernichow S, Galan P, Hercberg S, Oppert JM. Sedentary behaviours, physical activity, and metabolic syndrome in middle-aged French subjects. Obes Res. 2005; 13: 936–44
   PubMedGoogle Scholar
• Ford ES, Kohl HW, Mokdad AH, Ajani UA. Sedentary behaviour, physical activity, and the metabolic syndrome among U.S. adults. Obes Res. 2005; 13: 608–14
   PubMedGoogle Scholar
• Wannamethee SG, Shaper AG, Whincup PH. Modifiable lifestyle factors and the metabolic syndrome in older men: Effects of lifestyle changes. J Am Geriatr Soc. 2006; 54: 1909–14
   PubMed Web of Science ®Google Scholar
• Lakka TA, Laaksonen DE, Lakka HM, Mannikko N, Niskanen LK, Rauramaa R, et al. Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome. Med Sci Sports Exerc. 2003; 35: 1279–86
   PubMed Web of Science ®Google Scholar
• Panagiotakos DB, Pitsavos C, Chrysohoou C, Skoumas J, Tousoulis D, Toutouza M, et al. Impact of lifestyle habits on the prevalence of the metabolic syndrome among Greek adults from the Attica study. Am Heart J. 2004; 147: 106–12
   PubMed Web of Science ®Google Scholar
• Zhu S, St-Onge MP, Heshka S, Heymsfield SB. Lifestyle behaviors associated with lower risk of having the metabolic syndrome. Metabolism. 2004; 53: 1503–11
   PubMed Web of Science ®Google Scholar
• Santos, AC, Ebrahim S, Barros H. Alcohol intake, smoking, sleeping hours, physical activity and the metabolic syndrome. Prev Med. 2007 (Epub ahead of print).
   PubMedGoogle Scholar
• Katzmarzyk PT, Church TS, Blair SN. Cardiorespiratory fitness attenuates the effects of the metabolic syndrome on all-cause and cardiovascular disease mortality in men. Arch Intern Med. 2004; 164: 1092–7
   PubMed Web of Science ®Google Scholar
• Gustat J, Srinivasan SR, Elkasabany A, Berenson GS. Relation of self-rated measures of physical activity to multiple risk factors of insulin resistance syndrome in young adults: The Bogalusa Heart Study. J Clin Epidemiol. 2002; 55: 997–1006
   PubMed Web of Science ®Google Scholar
• Helge JW, Kriketos AD, Storlien LH. Insulin sensitivity, muscle fiber types, and membrane lipids. Adv Exp Med Biol. 1998; 441: 129–38
   PubMed Web of Science ®Google Scholar
• Irwin ML, Yasui Y, Ulrich CM, Bowen D, Rudolph RE, Schwartz RS, et al. Effect of exercise on total and intra-abdominal body fat in postmenopausal women. JAMA. 2003; 289: 323–30
   PubMed Web of Science ®Google Scholar
• Katzmarzyk PT, Leon AS, Wilmore JH, Skinner JS, Rao DC, Rankinen T, et al. Targeting the metabolic syndrome with exercise: Evidence from the HERITAGE Family Study. Med Sci Sports Exerc. 2003; 35: 1703–9
   PubMed Web of Science ®Google Scholar
• Bassuk SS, Manson JE. Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease. J Appl Physiol. 2005; 99: 1193–204
   PubMed Web of Science ®Google Scholar
• Pickering TG. The effects of environmental and lifestyle factors on blood pressure and the intermediary role of the sympathetic nervous system. J Hum Hypertens. 1997; 11(Suppl1)S9–18
   PubMedGoogle Scholar
• Carretero OA, Oparil S. Essential hypertension, part 1: Definition and epidemiology. Circulation. 2000; 101: 329–35
   PubMed Web of Science ®Google Scholar
• Julius S, Majahalme S. The changing face of sympathetic overactivity in hypertension. Ann Med. 2000; 32: 365–70
   PubMed Web of Science ®Google Scholar
• Fagard RH. Physical activity in the prevention and treatment of hypertension in the obese. Med Sci Sports Exerc. 1999; 31 Suppl: S624–30
   Web of Science ®Google Scholar
• Bassett DR, Jr, Fitzhugh EC, Crespo CJ, King GA, McLaughlin JE. Physical activity and ethnic differences in hypertension prevalence in the United States. Prev Med. 2002; 34: 179–86
   PubMed Web of Science ®Google Scholar
• Wareham NJ, Wong MY, Hennings S, Mitchell J, Rennie K, Cruickshank K, et al. Quantifying the association between habitual energy expenditure and blood pressure. Int J Epidemiol. 2000; 29: 655–60
   Google Scholar
• Blair SN, Goodyear NN, Gibbons LW, Cooper KH. Physical fitness and incidence of hypertension in healthy normotensive men and women. JAMA. 1984; 252: 487–90
   PubMed Web of Science ®Google Scholar
• Barlow CE, LaMonte MJ, FitzGerald SJ, Kampert JB, Perrin JL, Blair SN. Cardiorespiratory fitness is an independent predictor of hypertension incidence among initially normotensive healthy women. Am J Epidemiol. 2006; 163: 142–50
   PubMed Web of Science ®Google Scholar
• American College of Sports Medicine (ACSM). Position stand. Exercise and hypertension. Med Sci Sports Exerc. 2004;36:533–53.
   PubMedGoogle Scholar
• Fagard RH. Exercise characteristics and the blood pressure response to dynamic physical training. Med Sci Sports Exerc. 2001; 33 Suppl: S484–92
   Web of Science ®Google Scholar
• Whelton SP, Chin A, Xin X, He J. Effect of aerobic exercise on blood pressure: A meta-analysis of randomized, controlled trials. Ann Intern Med. 2002; 136: 493–503
   PubMed Web of Science ®Google Scholar
• Bacon SL, Sherwood A, Hinderliter A, Blumenthal JA. Effects of exercise, diet and weight loss on high blood pressure. Sports Med. 2004; 34: 307–16
   PubMed Web of Science ®Google Scholar
• Cornelissen VA, Fagard RH. Effect of resistance training on resting blood pressure: A meta-analysis of randomized controlled trials. J Hypertens. 2005; 23: 251–9
   PubMed Web of Science ®Google Scholar
• Ketelhut RG, Franz IW, Scholze J. Regular exercise as an effective approach in antihypertensive therapy. Med Sci Sports Exerc. 2004; 36: 4–8
   PubMed Web of Science ®Google Scholar
• Hagberg JM, Park JJ, Brown MD. The role of exercise training in the treatment of hypertension: An update. Sports Med. 2000; 30: 193–206
   PubMed Web of Science ®Google Scholar
• Blumenthal JA, Sherwood A, Gullette EC, Babyak M, Waugh R, Georgiades A, et al. Exercise and weight loss reduce blood pressure in men and women with mild hypertension: Effects on cardiovascular, metabolic, and hemodynamic functioning. Arch Intern Med. 2000; 160: 1947–58
   PubMed Web of Science ®Google Scholar
• Steffen PR, Sherwood A, Gullette EC, Georgiades A, Hinderliter A, Blumenthal JA. Effects of exercise and weight loss on blood pressure during daily life. Med Sci Sports Exerc. 2001; 33: 1635–40
   PubMed Web of Science ®Google Scholar
• Kokkinos PF, Narayan P, Papademetriou V. Exercise as hypertension therapy. Cardiol Clin. 2001; 19: 507–16
   PubMedGoogle Scholar
• Ehsani AA. Exercise in patients with hypertension. A review. Am J Geriatr Cardiol. 2001; 10: 253–9
   PubMedGoogle Scholar
• Georgiades A, Sherwood A, Gullette EC, Babyak MA, Hinderliter A, Waugh R, et al. Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure. Hypertension. 2000; 36: 171–6
   PubMed Web of Science ®Google Scholar
• Church TS, Kampert JB, Gibbons LW, Barlow CE, Blair SN. Usefulness of cardiorespiratory fitness as a predictor of all-cause and cardiovascular disease mortality in men with systemic hypertension. Am J Cardiol. 2001; 88: 51–6
   Google Scholar
• Kohl HW. Physical activity and cardiovascular disease: Evidence for a dose response. Med Sci Sports Exerc. 2001; 33 Suppl: 472–83
   Google Scholar
• Williams PT. Health effects resulting from exercise versus those from body fat loss. Med Sci Sports Exerc. 2001; 33 Suppl: S611–21
   Web of Science ®Google Scholar
• Schnor P, Jensen JS, Scharling H, Nordestgaard BG. Coronary heart disease risk ranked by importance for the individual and the community. A 21 year follow-up of 12 000 men and women from the Copenhagen City Heart Study. Eur Heart J. 2002; 23: 620–6
   PubMed Web of Science ®Google Scholar
• Paffenbarger RS, Hyde RT, Wing AL, Lee I-M, Dexter L, Kampert JB. The association of changes in physical activity level and other lifestyle characteristics with mortality among men. N Engl J Med. 1993; 328: 538–45
   PubMed Web of Science ®Google Scholar
• Lissner L, Bengtsson C, Björkelund C, Wedel H. Physical activity levels and changes in relation to longevity. Am J Epidemiol. 1996; 143: 54–62
   PubMed Web of Science ®Google Scholar
• Wannamethee SG, Shaper AG, Walker M. Changes in physical activity, mortality, and incidence of coronary heart disease in older men. Lancet. 1998; 351: 1603–8
   PubMed Web of Science ®Google Scholar
• Blair SN, Cheng Y, Holder JS. Is physical activity or physical fitness more important in defining health. Med Sci Sports Exerc. 2001; 33 Suppl: S379–99
   Web of Science ®Google Scholar
• Tegos TJ, Kalodiki E, Sabetai MM, Nicolaides AN. The genesis of atherosclerosis and risk factors: A review. Angiology. 2001; 52: 89–98
   PubMed Web of Science ®Google Scholar
• Giannuzzi P, Mezzani A, Saner H, Bjornstad H, Fioretti P, Mendes M, et al. Physical activity for primary and secondary prevention. Position paper of the Working group of Cardiac Rehabilitation and Exercise Physiology of the European Society of Cardiology. Eur J Cardiovasc Rehab. 2003; 10: 319–27
   PubMedGoogle Scholar
• Thompson PD, Buchner D, Pina IL, Balady GJ, Williams MA, Marcus BH, et al. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease: A Statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity). Circulation. 2003; 107: 3109–16
   PubMed Web of Science ®Google Scholar
• Whang W, Manson JE, Hu FB, Chae CU, Rexrode KM, Willett WC, Stampfer MJ, Albert CM, et al. Physical exertion, exercise, and sudden cardiac death in women. JAMA. 2006; 295: 1399–1403
   PubMed Web of Science ®Google Scholar
• Ades PA. Cardiac rehabilitation and secondary prevention of coronary heart disease. N Engl J Med. 2001; 345: 892–902
   PubMed Web of Science ®Google Scholar
• Taylor RS, Brown A, Ebrahim S, Jolliffe J, Noorani H, Rees K, et al. Exercise-based rehabilitation for patients with coronary heart disease: Systematic review and meta-analysis of randomized controlled trials. Am J Med. 2004; 116: 682–92
   PubMed Web of Science ®Google Scholar
• Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS, et al. ACC/AHA Guideline update for the management of patients with chronic stable angina. Summary article. Circulation. 2003;107:149–158. www.americanheart.org.
   PubMed Web of Science ®Google Scholar
• Leon AS, Franklin BA, Costa F, Balady GJ, Berra KA, Stewart KJ, et al. Cardiac rehabilitation and secondary prevention of coronary heart disease. AHA Scientific Statement. Circulation. 2005; 111: 369–76
   PubMed Web of Science ®Google Scholar
• Hambrecht R, Walther C, Mobius-Winkler S, Gielen S, Linke A, Conradi K, et al. Percutaneous coronary angioplasty compared with exercise training in patients with stable coronary artery disease: A randomized trial. Circulation. 2004; 109: 1371–8
   PubMed Web of Science ®Google Scholar
• Pina IL, Apstein CS, Balady GJ, Belardinelli R, Chaitman BR, Duscha BD, et al. Exercise and heart failure: A Statement from the Committee on Exercise, Rehabilitation, and Prevention. Circulation. 2003; 107: 1210–25
   PubMed Web of Science ®Google Scholar
• ExTraMATCH Collaborative. Exercise training meta-analysis of trials in patients with chronic heart failure. BMJ. 2004. doi:10.1136/bmj.37938.645220.EE (published 16 January 2004).
   Google Scholar
• Erbs S, Linke A, Gielen S, Fiehn E, Walther C, Yu J, et al. Exercise training in patients with severe chronic heart failure: Impact on left ventricular performance and cardiac size. A retrospective analysis of the Leipzig Heart Failure Training Trial. Eur J Cardiovasc Prevention Rehab. 2003; 10: 336–44
   PubMedGoogle Scholar
• Lee CD, Folsom AR, Blair SN. Physical activity and stroke risk. A meta-analysis. Stroke. 2003; 34: 2475–82
   PubMed Web of Science ®Google Scholar
• Oguma Y, Shinoda-Tagawa T. Physical activity decreases cardiovascular disease risk in women: Review and meta-analysis. Am J Prev Med. 2004; 26: 407–18
   PubMed Web of Science ®Google Scholar
• Wendel-Vos GC, Schuit AJ, Feskens EJ, Boshuizen HC, Verschuren WM, Saris WH, et al. Physical activity and stroke. A meta-analysis of observational data. Int J Epidemiol. 2004; 33: 787–98
   PubMed Web of Science ®Google Scholar
• Lee CD, Blair SN. Cardiorespiratory fitness and stroke mortality in men. Med Sci Sports Exerc. 2002; 34: 592–5
   PubMed Web of Science ®Google Scholar
• Goldstein LB, Adams R, Alberts MJ, Appel LJ, Brass LM, Bushnell CD, et al. Primary prevention of ischemic stroke: A guideline from the American Heart Association/American Stroke Association. Circulation. 2006; 113: e873–923
   PubMed Web of Science ®Google Scholar
• Sacco RL, Adams R, Albers G, Alberts MJ, Benavente O, Furie K, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: A statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke. Circulation. 2006; 113: e409–49
   PubMed Web of Science ®Google Scholar
• Fratiglioni L, Paillard-Borg S, Winblad B. An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol. 2004; 3: 343–53
   PubMed Web of Science ®Google Scholar
• Nash DT, Fillit H. Cardiovascular disease risk factors and cognitive impairment. Am J Cardiol. 2006; 97: 1262–5
   PubMed Web of Science ®Google Scholar
• Colcombe S, Kramer AF. Fitness effects on the cognitive function of older adults: A meta-analytic study. Psychol Sci. 2003; 14: 125–30
   PubMed Web of Science ®Google Scholar
• Abbott RD, White LR, Ross GW, Masaki KH, Curb JD, Petrovitch H. Walking and dementia in physically capable elderly men. JAMA. 2004; 292: 1447–53
   PubMed Web of Science ®Google Scholar
• Housley E, Leng GC, Donnan PT, Fowkes FGR. Physical activity and risk of peripheral arterial disease in the general population: Edinburgh Artery Study. J Epidemiol Community Health. 1993; 47: 475–80
   PubMed Web of Science ®Google Scholar
• Engstrom G, Ogren M, Hedblad B, Wollmer P, Janzon L. Asymptomatic leg atherosclerosis is reduced by regular physical activity: Longitudinal results from the cohort “Men born in 1914”. Eur J Endovasc Surg. 2001; 21: 502–7
   PubMed Web of Science ®Google Scholar
• Leng GC, Fowler B, Ernst E. Exercise for intermittent claudication. (Cochrane Review). The Cochrane Library, Issue 4. Chichester: John Wiley & Sons, Ltd.; 2004.
   Google Scholar
• Bulmer AC, Coombes JS. Optimising exercise training in peripheral arterial disease. Review article. Sports Med. 2004; 34: 983–1003
   PubMed Web of Science ®Google Scholar
• Parkkari J, Kannus P, Natri A, Lapinleimu I, Palvanen M, Heiskanen M, et al. Active living and injury risk. Int J Sports Med. 2004; 25: 209–16
   PubMed Web of Science ®Google Scholar
• Vuori I. Sudden death and exercise: Effects of age and type of activity. Sports Sci Rev. 1995; 4: 46–84
   Google Scholar
• Thompson PD. Exercise prescription and proscription for patients with coronary artery disease. Circulation. 2005; 112: 2354–63
   PubMed Web of Science ®Google Scholar
• Kohl HW, III, Lee I-M, Vuori I M, Wheeler F C, Bauman A, Sallis JF. The Emergence of a subdiscipline. Report from the International Congress on Physical Activity and Public Health, 17–21 April 2006, Atlanta, Georgia, USA. J Phys Activity Health. 2006; 3: 344–64
   PubMedGoogle Scholar