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Original Articles: Rheumatoid Arthritis

New adalimumab formulation associated with less injection site pain and improved motivation for treatment

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Pages 949-953 | Received 01 Nov 2017, Accepted 03 Sep 2018, Published online: 29 May 2019

References

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  • Frenken LA, van Lier HJ, Jordans JG, Leunissen KM, van Leusen R, Verstappen VM, et al. Identification of the component part in an epoetin alfa preparation that causes pain after subcutaneous injection. Am J Kidney Dis. 1993;22(4):553–6.
  • Frenken LAM, van Lier HJI, Koene RAP. Analysis of the efficacy of measures to reduce pain after subcutaneous administration of epoetin alfa. Nephrol Dial Transplant. 1994;9(9):1295–8.
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  • Laursen T, Hansen B, Fisker S. Pain perception after subcutaneous injections of media containing different buffers. Basic Clin Pharmacol Toxicol. 2006;98(2):218–21.
  • Bolge S, Eldridge H, Doshi D, et. al. Patient satisfaction and experience with golimumab, adalimumab, and etanercept for the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. Arthritis Rheum. 2012;64:817.
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  • Nash P, Vanhoof J, Hall S, Arulmani U, Tarzynski-Potempa R, Unnebrink K, et al. Randomized crossover comparison of injection site pain with 40 mg/0.4 or 0.8 ml formulations of adalimumab in patients with rheumatoid arthritis. Rheumatol Ther. 2016;3(2):257–70.

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